A new multifunctional hydroxytyrosol-fenofibrate with antidiabetic, antihyperlipidemic, antioxidant and antiinflammatory action

Biomedicine and Pharmacotherapy

Volumn 95, Issue , 2017, Pages 1749-1758

  Xie, Yundong ^a   Xu, Yanhong ^a   Chen, Zizhang ^a   Lu, Wenfang ^c   Li, Na ^b   Wang, Qiutang ^a   Shao, Lihua ^a   Li, Yiping ^a   Yang, Guangde ^a   Bian, Xiaoli ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b SHAANXI UNIVERSITY OF CHINESE MEDICINE   (China)

^c Xianyang Central Hospital   (China)

Author keywords

Anti diabetes; Anti inflammation; Antihyperlipidemia; Antioxidant; Hydroxytyrosol fenofibrate

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; C REACTIVE PROTEIN; CATALASE; CHOLESTEROL; FENOFIBRATE; GLUCOSE; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYTYROSOL; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR; TYLOXAPOL; TYROSOL; 3,4-DIHYDROXYPHENYLETHANOL; 4-HYDROXYPHENYLETHANOL; ANTIDIABETIC AGENT; ANTIINFLAMMATORY AGENT; ANTILIPEMIC AGENT; ANTIOXIDANT; PHENETHYL ALCOHOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIHYPERLIPIDEMIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETIC COMPLICATION; HISTOLOGY; HISTOPATHOLOGY; HYPERLIPIDEMIA; IC50; IN VITRO STUDY; LIPID LIVER LEVEL; LIPID STORAGE; LIVER TISSUE; LIVER TOXICITY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS TISSUE; PRIORITY JOURNAL; SINGLE DRUG DOSE; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DRUG DESIGN; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; INSTITUTE FOR CANCER RESEARCH MOUSE; MEDICINAL CHEMISTRY; OXIDATIVE STRESS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CHEMISTRY, PHARMACEUTICAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DRUG DESIGN; FENOFIBRATE; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; MALE; MICE; MICE, INBRED ICR; OXIDATIVE STRESS; PHENYLETHYL ALCOHOL;

EID: 85029805897     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.09.073     Document Type: Article

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