Bixin activates PPARα and improves obesity-induced abnormalities of carbohydrate and lipid metabolism in mice

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 48, 2012, Pages 11952-11958

  Goto, Tsuyoshi ^a,b   Takahashi, Nobuyuki ^a,b   Kato, Sota ^b   Kim, Young Il ^b   Kusudo, Tatsuya ^b   Taimatsu, Aki ^b   Egawa, Kahori ^b   Kang, Min Sook ^b   Hiramatsu, Takuro ^b   Sakamoto, Tomoya ^b   Uemura, Taku ^b   Hirai, Shizuka ^b   Kobayashi, Misato ^c   Horio, Fumihiko ^c   Kawada, Teruo ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

bixin; energy metabolism; hepatocyte; norbixin; PPAR

Indexed keywords

BIXIN; CARBOHYDRATE METABOLISM; ENERGY METABOLISM; FATTY ACID OXIDATION; FOOD COLORING; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HEPATOCYTES; HYPERLIPIDEMIA; INSULIN RESISTANCE; LIPID ACCUMULATIONS; LIPID METABOLISMS; LUCIFERASE REPORTER ASSAYS; MRNA EXPRESSION; MRNA LEVEL; NORBIXIN; OBESE MICE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; TARGET GENES;

CARBOHYDRATES; CYTOLOGY; GENES; GLUCOSE; INSULIN; METABOLISM; NUTRITION; OXIDATION; PHYSIOLOGY; TRANSCRIPTION FACTORS;

MAMMALS;

ADIPONECTIN; ADIPOQ PROTEIN, MOUSE; BIXIN; CAROTENOID; NORBIXIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ANIMAL; ARTICLE; BLOOD; CARBOHYDRATE METABOLISM; DRUG EFFECT; FATTY LIVER; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE TOLERANCE TEST; HYPERLIPIDEMIA; LIPID DIET; LIPID METABOLISM; LIVER CELL; MALE; METABOLISM; MOUSE; MOUSE MUTANT; OBESITY; PHYSIOLOGY;

ADIPONECTIN; ANIMALS; CARBOHYDRATE METABOLISM; CAROTENOIDS; DIET, HIGH-FAT; FATTY LIVER; GENE EXPRESSION REGULATION; GLUCOSE TOLERANCE TEST; HEPATOCYTES; HYPERLIPIDEMIAS; LIPID METABOLISM; MALE; MICE; MICE, OBESE; OBESITY; PPAR ALPHA;

MUS;

EID: 84870694688     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf303639f     Document Type: Article

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