Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 37, 2017, Pages 9870-9875

  Johnson, Kirsten M ^a,b   Mahler, Nathan R ^a   Saund, Ranajeet S ^b   Theisen, Emily R ^b   Taslim, Cenny ^b   Callender, Nathan W ^b   Crow, Jesse C ^b   Miller, Kyle R ^b   Lessnick, Stephen L ^a,b,c  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA BINDING PROTEIN EWS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TPI; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CELL RECEPTOR; DNA BINDING PROTEIN; EWSR1 PROTEIN, HUMAN; FLII PROTEIN, HUMAN; FUSION PROTEIN; MICROSATELLITE DNA; NR0B1 PROTEIN, HUMAN; NUCLEAR RECEPTOR DAX 1;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; BIOCHEMICAL ANALYSIS; CONTROLLED STUDY; EMBRYO; EWING SARCOMA; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NR0B1 GENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; STOICHIOMETRY; TRANSCRIPTION INITIATION; CELL PROLIFERATION; CRISPR CAS SYSTEM; DNA RESPONSIVE ELEMENT; GENETICS; HEK293 CELL LINE; METABOLISM; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL PROLIFERATION; CRISPR-CAS SYSTEMS; DAX-1 ORPHAN NUCLEAR RECEPTOR; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; MICROFILAMENT PROTEINS; MICROSATELLITE REPEATS; PROTEIN DOMAINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; RESPONSE ELEMENTS; RNA-BINDING PROTEIN EWS; SARCOMA, EWING;

EID: 85029476765     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1701872114     Document Type: Article

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