Comparison of different in vitro cell models for the assessment of pesticide-induced dopaminergic neurotoxicity

Toxicology in Vitro

Volumn 45, Issue , 2017, Pages 81-88

  Heusinkveld, Harm J ^a   Westerink, Remco H S ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Cell viability; Fura 2 Ca2+ imaging; In vitro hazard characterization; In vitro neurotoxicity screening; Oxidative stress

Indexed keywords

CALCIUM ION; DICHLORODIHYDROFLUORESCEIN DIACETATE; DIELDRIN; DINOSEB; DOPAMINE; ENILCONAZOLE; FURA 2; ION CHANNEL; LINDANE; MEMBRANE RECEPTOR; PESTICIDE; REACTIVE OXYGEN METABOLITE; ROTENONE; CALCIUM; NEUROTRANSMITTER RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CATECHOLAMINE NERVE CELL; CELL VIABILITY; CELLULAR STRESS RESPONSE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE MODEL; DOPAMINERGIC TRANSMISSION; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; IN VITRO STUDY; MES23.5 CELL LINE; MOUSE; N27 CELL LINE; NERVE CELL CULTURE; NERVE CELL MEMBRANE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PC12 CELL LINE; RAT; RESAZURIN ASSAY; SH-SY5Y CELL LINE; SINGLE CELL ANALYSIS; ANIMAL; CELL LINE; CELL SURVIVAL; DRUG EFFECT; METABOLISM; NERVE CELL; POLLUTANT; TOXICITY;

ANIMALS; CALCIUM; CELL LINE; CELL SURVIVAL; DOPAMINE; ENVIRONMENTAL POLLUTANTS; HUMANS; ION CHANNELS; NEURONS; PESTICIDES; RATS; RECEPTORS, NEUROTRANSMITTER;

EID: 85028502314     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2017.07.030     Document Type: Article

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