Tranexamic acid impairs γ-aminobutyric acid receptor type a-mediated synaptic transmission in the murine amygdala: A potential mechanism for drug-induced seizures?

Anesthesiology

Volumn 120, Issue 3, 2014, Pages 639-649

  Kratzer, Stephan ^a   Irl, Hedwig ^a   Mattusch, Corinna ^a   Bürge, Martina ^a   Kurz, Jörg ^b   Kochs, Eberhard ^a   Eder, Matthias ^c   Rammes, Gerhard ^a   Haseneder, Rainer ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; TRANEXAMIC ACID;

ANIMAL TISSUE; ARTICLE; BASOLATERAL AMYGDALA; BRAIN SLICE; CONTROLLED STUDY; CONVULSION; ELECTROSTIMULATION; IC 50; MALE; MOUSE; NERVE EXCITABILITY; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; PULSE RATE; SYNAPTIC TRANSMISSION; VOLTAGE SENSITIVE DYE IMAGING;

AMYGDALA; ANIMALS; ANTIFIBRINOLYTIC AGENTS; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; MALE; MICE; MICE, INBRED C57BL; PATCH-CLAMP TECHNIQUES; PHOTOLYSIS; RECEPTORS, GABA-A; SEIZURES; SYNAPTIC TRANSMISSION; TRANEXAMIC ACID;

EID: 84895486195     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000000103     Document Type: Article

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