ISG'ylation increases stability of numerous proteins including Stat1, which prevents premature termination of immune response in LPS-stimulated microglia

Neurochemistry International

Volumn 112, Issue , 2018, Pages 227-233

  Przanowski, Piotr ^a   Loska, Stefan ^a   Cysewski, Dominik ^b   Dabrowski, Michal ^a   Kaminska, Bozena ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

Inflammation; ISG'ylation; ISG15; Mass spectrometry; Microglia; STAT1; UBA7

Indexed keywords

ENZYME; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; LYSINE; MESSENGER RNA; PROTEIN HERC5; PROTEIN HERC6; PROTEIN ISG15; PROTEIN UBA7; PROTEIN UBCH8; PROTEIN UBE2L6; RANTES; STAT1 PROTEIN; UNCLASSIFIED DRUG; CYTOKINE; G1P2 PROTEIN, MOUSE; STAT1 PROTEIN, MOUSE; UBIQUITIN;

ANIMAL CELL; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; IMMUNE RESPONSE; ISG'YLATION; MASS SPECTROMETRY; MICROGLIAL CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN TARGETING; ANIMAL; CELLULAR IMMUNITY; DRUG EFFECT; METABOLISM; MICROGLIA; MOUSE; NEWBORN; PHYSIOLOGY; RAT; TRANSFORMED CELL LINE; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; CELL LINE, TRANSFORMED; CYTOKINES; IMMUNITY, CELLULAR; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; PROTEIN STABILITY; RATS; RATS, WISTAR; STAT1 TRANSCRIPTION FACTOR; UBIQUITINS;

EID: 85028048773     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2017.07.013     Document Type: Article

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