Interferon-stimulated gene 15, a type i interferon-dependent transcript, is involved in a negative feedback loop in innate immune reactions in human mesangial cells

Nephron

Volumn 132, Issue 2, 2016, Pages 144-152

  Imaizumi, Tadaatsu ^a   Shimada, Taku ^a   Matsumiya, Tomoh ^a   Yoshida, Hidemi ^a   Watanabe, Shojiro ^a   Tsuruga, Kazushi ^a   Kawaguchi, Shogo ^a   Murakami, Manabu ^a   Joh, Kensuke ^b   Tanaka, Hiroshi ^a  

^a HIROSAKI UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

CXCL10; Glomerulonephritis; IFN ; ISG15; Mesangial cells; Phosphorylated STAT1; Poly IC; TLR3; USP18

Indexed keywords

INTERFERON STIMULATED GENE FACTOR 15; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5; POLYINOSINIC POLYCYTIDYLIC ACID; SMALL INTERFERING RNA; STAT1 PROTEIN; TOLL LIKE RECEPTOR 3; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BETA INTERFERON; CXCL10 PROTEIN, HUMAN; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON; ISG15 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; UBIQUITIN;

ARTICLE; GENE EXPRESSION REGULATION; GENE SILENCING; GLOMERULONEPHRITIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNE DYSREGULATION; INNATE IMMUNITY; MESANGIUM CELL; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CELL CULTURE; GENETICS; IMMUNOLOGY; PHYSIOLOGICAL FEEDBACK; PHYSIOLOGY;

CELLS, CULTURED; CHEMOKINE CXCL10; CYTOKINES; FEEDBACK, PHYSIOLOGICAL; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; INTERFERON-BETA; MESANGIAL CELLS; POLY I-C; TOLL-LIKE RECEPTOR 3; UBIQUITINS;

EID: 84959204338     PISSN: 16608151     EISSN: 22353186     Source Type: Journal    
DOI: 10.1159/000443934     Document Type: Article

References (23)

1. Robson MG: Toll-like receptors and renal disease. Nephron Exp Nephrol 2009;113:e1-e7.
2. Coppo R, Amore A, Peruzzi L, Vergano L, Camilla R: Innate immunity and IgA nephropathy. J Nephrol 2010;23:626-632.
3. Anders HJ: Pseudoviral immunity-a novel concept for lupus. Trends Mol Med 2009;15:553-561.
4. Tanaka H, Imaizumi T: Inflammatory chemokine expression via toll-like receptor 3 signaling in normal human mesangial cells. Clin Dev Immunol 2013;2013:984708.
5. Imaizumi T, Tanaka H, Matsumiya T, Yoshida H, Tanji K, Tsuruga K, Oki E, Aizawa-Yashiro T, Ito E, Satoh K: Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CC chemokine ligand (CCL) 5 in human mesangial cells. Nephrol Dial Transplant 2010;25:3534-3539.
6. Imaizumi T, Tanaka H, Mechti N, Matsumiya T, Yoshida H, Sato F, Aizawa-Yashiro T, Tsuruga K, Hayakari R, Satoh K: Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells. Nephron Exp Nephrol 2011;119:e40-e48.
7. Imaizumi T, Aizawa-Yashiro T, Tsuruga K, Tanaka H, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Hayakari R, Satoh K: Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells: implications for chronic inflammatory renal diseases. Tohoku J Exp Med 2012;228:17-26.
8. Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H: Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in toll-like receptor 3 signaling in normal human mesangial cells. Am J Nephrol 2013;37:118-125.
9. Imaizumi T, Aizawa T, Segawa C, Shimada M, Tsuruga K, Kawaguchi S, Matsumiya T, Yoshida H, Joh K, Tanaka H: Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells. Clin Exp Nephrol 2015;19:761-770.
10. Aizawa-Yashiro T, Imaizumi T, Tsuruga K, Watanabe S, Matsumiya T, Hayakari R, Yoshida H, Satoh K, Ito E, Tanaka H: Glomerular expression of fractalkine is induced by polyinosinic-polycytidylic acid in human mesangial cells: possible involvement of fractalkine after viral infection. Pediatr Res 2013;73:180-186.
11. Feng X, Wu H, Grossman JM, Hanvivadhanakul P, FitzGerald JD, Park GS, Dong X, Chen W, Kim MH, Weng HH, Furst DE, Gorn A, McMahon M, Taylor M, Brahn E, Hahn BH, Tsao BP: Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus. Arthritis Rheum 2006;54:2951-2962.
12. Haas AL, Ahrens P, Bright PM, Ankel H: Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin. J Biol Chem 1987;262:11315-11323.
13. Nielsch U, Pine R, Zimmer SG, Babiss LE: Induced expression of the endogenous beta interferon gene in adenovirus type 5-transformed rat fibroblasts. J Virol 1992;66:1884-1890.
14. Jeon YJ, Yoo HM, Chung CH: ISG15 and immune diseases. Biochim Biophys Acta 2010;1802:485-496.
15. Zhao C, Denison C, Huibregtse JM, Gygi S, Krug RM: Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways. Proc Natl Acad Sci USA 2005;102:10200-10205.
16. Migliorini A, Ebid R, Scherbaum CR, Anders HJ: The danger control concept in kidney disease: mesangial cells. J Nephrol 2013;26:437-449.
17. Watanabe S, Imaizumi T, Tsuruga K, Aizawa T, Ito T, Matsumiya T, Yoshida H, Joh K, Ito E, Tanaka H: Glomerular expression of myxovirus resistance protein 1 in human mesangial cells: possible activation of innate immunity in the pathogenesis of lupus nephritis. Nephrology (Carlton) 2013;18:833-837.
18. Zhang X, Bogunovic D, Payelle-Brogard B, Francois-Newton V, Speer SD, Yuan C, Volpi S, Li Z, Sanal O, Mansouri D, Tezcan I, Rice GI, Chen C, Mansouri N, Mahdaviani SA, Itan Y, Boisson B, Okada S, Zeng L, Wang X, Jiang H, Liu W, Han T, Liu D, Ma T, Wang B, Liu M, Liu JY, Wang QK, Yalnizoglu D, Radoshevich L, Uzé G, Gros P, Rozenberg F, Zhang SY, Jouanguy E, Bustamante J, García-Sastre A, Abel L, Lebon P, Notarangelo LD, Crow YJ, Boisson-Dupuis S, Casanova JL, Pellegrini S: Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation. Nature 2015;517:89-93.
19. Osiak A, Utermöhlen O, Niendorf S, Horak I, Knobeloch KP: ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus. Mol Cell Biol 2005;25:6338-6345.
20. Kim JH, Luo JK, Zhang DE: The level of hepatitis B virus replication is not affected by protein ISG15 modification but is reduced by inhibition of UBP43 (USP18) expression. J Immunol 2008;181:6467-6472.
21. Malakhova OA, Kim KI, Luo JK, Zou W, Kumar KG, Fuchs SY, Shuai K, Zhang DE: UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. EMBO J 2006;25:2358-2367.
22. Malakhov MP, Kim KI, Malakhova OA, Jacobs BS, Borden EC, Zhang DE: High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction. J Biol Chem 2003;278:16608-16613.
23. Bogunovic D, Byun M, Durfee LA, Abhyankar A, Sanal O, Mansouri D, Salem S, Radovanovic I, Grant AV, Adimi P, Mansouri N, Okada S, Bryant VL, Kong XF, Kreins A, Velez MM, Boisson B, Khalilzadeh S, Ozcelik U, Darazam IA, Schoggins JW, Rice CM, Al-Muhsen S, Behr M, Vogt G, Puel A, Bustamante J, Gros P, Huibregtse JM, Abel L, Boisson-Dupuis S, Casanova JL: Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency. Science 2012;337:1684-1688.