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Volumn 33, Issue 34, 2012, Pages 8771-8781

Sustained protection against photoreceptor degeneration in tubby mice by intravitreal injection of nanoceria

Author keywords

Antioxidant; Gene expression; Longevity; Nanoceria; Retinal degeneration; Tubby mouse

Indexed keywords

ANTIOXIDANTS; DRUG THERAPY; EYE PROTECTION; GENES; MAMMALS; OPHTHALMOLOGY; VISION;

EID: 85027950910     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.08.030     Document Type: Article
Times cited : (83)

References (61)
  • 1
    • 15844372440 scopus 로고    scopus 로고
    • Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family
    • Kleyn P.W., Fan W., Kovats S.G., Lee J.J., Pulido J.C., Wu Y., et al. Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family. Cell 1996, 85:281-290.
    • (1996) Cell , vol.85 , pp. 281-290
    • Kleyn, P.W.1    Fan, W.2    Kovats, S.G.3    Lee, J.J.4    Pulido, J.C.5    Wu, Y.6
  • 3
    • 0028972472 scopus 로고
    • Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15
    • Heckenlively J.R., Chang B., Erway L.C., Peng C., Hawes N.L., Hageman G.S., et al. Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15. Proc Natl Acad Sci U S A 1995, 92:11100-11104.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11100-11104
    • Heckenlively, J.R.1    Chang, B.2    Erway, L.C.3    Peng, C.4    Hawes, N.L.5    Hageman, G.S.6
  • 5
    • 33244478094 scopus 로고    scopus 로고
    • Bright cyclic light accelerates photoreceptor cell degeneration in tubby mice
    • Kong L., Li F., Soleman C.E., Li S., Elias R.V., Zhou X., et al. Bright cyclic light accelerates photoreceptor cell degeneration in tubby mice. Neurobiol Dis 2006, 21:468-477.
    • (2006) Neurobiol Dis , vol.21 , pp. 468-477
    • Kong, L.1    Li, F.2    Soleman, C.E.3    Li, S.4    Elias, R.V.5    Zhou, X.6
  • 6
    • 0038662649 scopus 로고    scopus 로고
    • Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice
    • Bode C., Wolfrum U. Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice. Mol Vis 2003, 9:144-150.
    • (2003) Mol Vis , vol.9 , pp. 144-150
    • Bode, C.1    Wolfrum, U.2
  • 7
    • 0035874928 scopus 로고    scopus 로고
    • Transcription. Translocating tubby
    • Cantley L.C. Transcription. Translocating tubby. Science 2001, 292:2019-2021.
    • (2001) Science , vol.292 , pp. 2019-2021
    • Cantley, L.C.1
  • 8
    • 27544459505 scopus 로고    scopus 로고
    • Pharmacological consequences of oxidative stress in ocular tissues
    • Ohia S.E., Opere C.A., Leday A.M. Pharmacological consequences of oxidative stress in ocular tissues. Mutat Res 2005, 579:22-36.
    • (2005) Mutat Res , vol.579 , pp. 22-36
    • Ohia, S.E.1    Opere, C.A.2    Leday, A.M.3
  • 9
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • Beatty S., Koh H., Phil M., Henson D., Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000, 45:115-134.
    • (2000) Surv Ophthalmol , vol.45 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Phil, M.3    Henson, D.4    Boulton, M.5
  • 10
    • 77949890579 scopus 로고    scopus 로고
    • Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture
    • Hollyfield J.G. Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture. Invest Ophthalmol Vis Sci 2010, 51:1275-1281.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 1275-1281
    • Hollyfield, J.G.1
  • 11
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration: where are we now?
    • Halliwell B. Oxidative stress and neurodegeneration: where are we now?. J Neurochem 2006, 97:1634-1658.
    • (2006) J Neurochem , vol.97 , pp. 1634-1658
    • Halliwell, B.1
  • 14
    • 79960566171 scopus 로고    scopus 로고
    • A phosphate-dependent shift in redox state of cerium oxide nanoparticles and its effects on catalytic properties
    • Singh S., Dosani T., Karakoti A.S., Kumar A., Seal S., Self W.T. A phosphate-dependent shift in redox state of cerium oxide nanoparticles and its effects on catalytic properties. Biomaterials 2011, 32:6745-6753.
    • (2011) Biomaterials , vol.32 , pp. 6745-6753
    • Singh, S.1    Dosani, T.2    Karakoti, A.S.3    Kumar, A.4    Seal, S.5    Self, W.T.6
  • 15
    • 33846314024 scopus 로고    scopus 로고
    • Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons
    • Das M., Patil S., Bhargava N., Kang J.F., Riedel L.M., Seal S., et al. Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons. Biomaterials 2007, 28:1918-1925.
    • (2007) Biomaterials , vol.28 , pp. 1918-1925
    • Das, M.1    Patil, S.2    Bhargava, N.3    Kang, J.F.4    Riedel, L.M.5    Seal, S.6
  • 16
    • 79951576940 scopus 로고    scopus 로고
    • Combined cytotoxic and anti-invasive properties of redox-active nanoparticles in tumor-stroma interactions
    • Alili L., Sack M., Karakoti A.S., Teuber S., Puschmann K., Hirst S.M., et al. Combined cytotoxic and anti-invasive properties of redox-active nanoparticles in tumor-stroma interactions. Biomaterials 2011, 32:2918-2929.
    • (2011) Biomaterials , vol.32 , pp. 2918-2929
    • Alili, L.1    Sack, M.2    Karakoti, A.S.3    Teuber, S.4    Puschmann, K.5    Hirst, S.M.6
  • 17
    • 34250367839 scopus 로고    scopus 로고
    • Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides
    • Chen J., Patil S., Seal S., McGinnis J.F. Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides. Nat Nanotechnol 2006, 1:142-150.
    • (2006) Nat Nanotechnol , vol.1 , pp. 142-150
    • Chen, J.1    Patil, S.2    Seal, S.3    McGinnis, J.F.4
  • 18
    • 79952062512 scopus 로고    scopus 로고
    • Nanoceria inhibit the development and promote the regression of pathologic retinal neovascularization in the Vldlr knockout mouse
    • Zhou X., Wong L.L., Karakoti A.S., Seal S., McGinnis J.F. Nanoceria inhibit the development and promote the regression of pathologic retinal neovascularization in the Vldlr knockout mouse. PLoS One 2011, 6:e16733.
    • (2011) PLoS One , vol.6
    • Zhou, X.1    Wong, L.L.2    Karakoti, A.S.3    Seal, S.4    McGinnis, J.F.5
  • 19
    • 79954632189 scopus 로고    scopus 로고
    • Nanoceria extend photoreceptor cell lifespan in tubby mice by modulation of apoptosis/survival signaling pathways
    • Kong L., Cai X., Zhou X., Wong L.L., Karakoti A.S., Seal S., et al. Nanoceria extend photoreceptor cell lifespan in tubby mice by modulation of apoptosis/survival signaling pathways. Neurobiol Dis 2011, 42:514-523.
    • (2011) Neurobiol Dis , vol.42 , pp. 514-523
    • Kong, L.1    Cai, X.2    Zhou, X.3    Wong, L.L.4    Karakoti, A.S.5    Seal, S.6
  • 21
    • 84855932319 scopus 로고    scopus 로고
    • Neovascularization: ocular diseases, animal models and therapies
    • Cai X., Sezate S.A., McGinnis J.F. Neovascularization: ocular diseases, animal models and therapies. Adv Exp Med Biol 2012, 723:245-252.
    • (2012) Adv Exp Med Biol , vol.723 , pp. 245-252
    • Cai, X.1    Sezate, S.A.2    McGinnis, J.F.3
  • 22
    • 65449178420 scopus 로고    scopus 로고
    • A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles
    • Cai X., Nash Z., Conley S.M., Fliesler S.J., Cooper M.J., Naash M.I. A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles. PLoS One 2009, 4:e5290.
    • (2009) PLoS One , vol.4
    • Cai, X.1    Nash, Z.2    Conley, S.M.3    Fliesler, S.J.4    Cooper, M.J.5    Naash, M.I.6
  • 23
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29:e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 24
    • 67650802500 scopus 로고    scopus 로고
    • Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress
    • Dorrell M.I., Aguilar E., Jacobson R., Yanes O., Gariano R., Heckenlively J., et al. Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress. J Clin Invest 2009, 119:611-623.
    • (2009) J Clin Invest , vol.119 , pp. 611-623
    • Dorrell, M.I.1    Aguilar, E.2    Jacobson, R.3    Yanes, O.4    Gariano, R.5    Heckenlively, J.6
  • 25
    • 33645748724 scopus 로고    scopus 로고
    • Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors
    • Farjo R., Skaggs J.S., Nagel B.A., Quiambao A.B., Nash Z.A., Fliesler S.J., et al. Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors. J Cell Biol 2006, 173:59-68.
    • (2006) J Cell Biol , vol.173 , pp. 59-68
    • Farjo, R.1    Skaggs, J.S.2    Nagel, B.A.3    Quiambao, A.B.4    Nash, Z.A.5    Fliesler, S.J.6
  • 26
    • 34247558673 scopus 로고    scopus 로고
    • Delay of photoreceptor degeneration in tubby mouse by sulforaphane
    • Kong L., Tanito M., Huang Z., Li F., Zhou X., Zaharia A., et al. Delay of photoreceptor degeneration in tubby mouse by sulforaphane. J Neurochem 2007, 101:1041-1052.
    • (2007) J Neurochem , vol.101 , pp. 1041-1052
    • Kong, L.1    Tanito, M.2    Huang, Z.3    Li, F.4    Zhou, X.5    Zaharia, A.6
  • 27
    • 66149103602 scopus 로고    scopus 로고
    • Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver
    • Cohen J.I., Roychowdhury S., DiBello P.M., Jacobsen D.W., Nagy L.E. Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver. Hepatology 2009, 49:1709-1717.
    • (2009) Hepatology , vol.49 , pp. 1709-1717
    • Cohen, J.I.1    Roychowdhury, S.2    DiBello, P.M.3    Jacobsen, D.W.4    Nagy, L.E.5
  • 28
    • 3142721782 scopus 로고    scopus 로고
    • Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage
    • Gao X., Talalay P. Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proc Natl Acad Sci U S A 2004, 101:10446-10451.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10446-10451
    • Gao, X.1    Talalay, P.2
  • 29
    • 77952543205 scopus 로고    scopus 로고
    • Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice
    • Kong L., Zhou X., Li F., Yodoi J., McGinnis J., Cao W. Neuroprotective effect of overexpression of thioredoxin on photoreceptor degeneration in Tubby mice. Neurobiol Dis 2010, 38:446-455.
    • (2010) Neurobiol Dis , vol.38 , pp. 446-455
    • Kong, L.1    Zhou, X.2    Li, F.3    Yodoi, J.4    McGinnis, J.5    Cao, W.6
  • 31
    • 16244378900 scopus 로고    scopus 로고
    • Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice
    • Tanito M., Masutani H., Kim Y.C., Nishikawa M., Ohira A., Yodoi J. Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice. Invest Ophthalmol Vis Sci 2005, 46:979-987.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 979-987
    • Tanito, M.1    Masutani, H.2    Kim, Y.C.3    Nishikawa, M.4    Ohira, A.5    Yodoi, J.6
  • 33
    • 0036264862 scopus 로고    scopus 로고
    • Photoreceptor renewal: a role for peripherin/rds
    • Boesze-Battaglia K., Goldberg A.F. Photoreceptor renewal: a role for peripherin/rds. Int Rev Cytol 2002, 217:183-225.
    • (2002) Int Rev Cytol , vol.217 , pp. 183-225
    • Boesze-Battaglia, K.1    Goldberg, A.F.2
  • 34
    • 0026078839 scopus 로고
    • Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse
    • Connell G., Bascom R., Molday L., Reid D., McInnes R.R., Molday R.S. Photoreceptor peripherin is the normal product of the gene responsible for retinal degeneration in the rds mouse. Proc Natl Acad Sci U S A 1991, 88:723-726.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 723-726
    • Connell, G.1    Bascom, R.2    Molday, L.3    Reid, D.4    McInnes, R.R.5    Molday, R.S.6
  • 35
    • 0023064180 scopus 로고
    • Peripherin. A rim-specific membrane protein of rod outer segment discs
    • Molday R.S., Hicks D., Molday L. Peripherin. A rim-specific membrane protein of rod outer segment discs. Invest Ophthalmol Vis Sci 1987, 28:50-61.
    • (1987) Invest Ophthalmol Vis Sci , vol.28 , pp. 50-61
    • Molday, R.S.1    Hicks, D.2    Molday, L.3
  • 36
    • 32944462134 scopus 로고    scopus 로고
    • Commentary: an aye for eye gene therapy
    • Bennett J. Commentary: an aye for eye gene therapy. Hum Gene Ther 2006, 17:177-179.
    • (2006) Hum Gene Ther , vol.17 , pp. 177-179
    • Bennett, J.1
  • 39
    • 3843127507 scopus 로고    scopus 로고
    • SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I
    • Qi X., Lewin A.S., Sun L., Hauswirth W.W., Guy J. SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I. Ann Neurol 2004, 56:182-191.
    • (2004) Ann Neurol , vol.56 , pp. 182-191
    • Qi, X.1    Lewin, A.S.2    Sun, L.3    Hauswirth, W.W.4    Guy, J.5
  • 40
    • 77956514096 scopus 로고    scopus 로고
    • Unveiling the mechanism of uptake and sub-cellular distribution of cerium oxide nanoparticles
    • Singh S., Kumar A., Karakoti A., Seal S., Self W.T. Unveiling the mechanism of uptake and sub-cellular distribution of cerium oxide nanoparticles. Mol Biosyst 2010, 6:1813-1820.
    • (2010) Mol Biosyst , vol.6 , pp. 1813-1820
    • Singh, S.1    Kumar, A.2    Karakoti, A.3    Seal, S.4    Self, W.T.5
  • 41
    • 30644473786 scopus 로고    scopus 로고
    • Vacancy engineered ceria nanostructures for protection from radiation-induced cellular damage
    • Tarnuzzer R.W., Colon J., Patil S., Seal S. Vacancy engineered ceria nanostructures for protection from radiation-induced cellular damage. Nano Lett 2005, 5:2573-2577.
    • (2005) Nano Lett , vol.5 , pp. 2573-2577
    • Tarnuzzer, R.W.1    Colon, J.2    Patil, S.3    Seal, S.4
  • 42
    • 42049113200 scopus 로고    scopus 로고
    • The role of cerium redox state in the SOD mimetic activity of nanoceria
    • Heckert E.G., Karakoti A.S., Seal S., Self W.T. The role of cerium redox state in the SOD mimetic activity of nanoceria. Biomaterials 2008, 29:2705-2709.
    • (2008) Biomaterials , vol.29 , pp. 2705-2709
    • Heckert, E.G.1    Karakoti, A.S.2    Seal, S.3    Self, W.T.4
  • 43
    • 33847304591 scopus 로고    scopus 로고
    • Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles
    • Korsvik C., Patil S., Seal S., Self W.T. Superoxide dismutase mimetic properties exhibited by vacancy engineered ceria nanoparticles. Chem Commun 2007, 1056-1058.
    • (2007) Chem Commun , pp. 1056-1058
    • Korsvik, C.1    Patil, S.2    Seal, S.3    Self, W.T.4
  • 45
    • 33748869718 scopus 로고    scopus 로고
    • Rod and cone opsin mislocalization in an autopsy eye from a carrier of X-linked retinitis pigmentosa with a Gly436Asp mutation in the RPGR gene
    • Adamian M., Pawlyk B.S., Hong D.H., Berson E.L. Rod and cone opsin mislocalization in an autopsy eye from a carrier of X-linked retinitis pigmentosa with a Gly436Asp mutation in the RPGR gene. Am J Ophthalmol 2006, 142:515-518.
    • (2006) Am J Ophthalmol , vol.142 , pp. 515-518
    • Adamian, M.1    Pawlyk, B.S.2    Hong, D.H.3    Berson, E.L.4
  • 46
    • 77955199065 scopus 로고    scopus 로고
    • Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration
    • Concepcion F., Chen J. Q344ter mutation causes mislocalization of rhodopsin molecules that are catalytically active: a mouse model of Q344ter-induced retinal degeneration. PLoS One 2010, 5:e10904.
    • (2010) PLoS One , vol.5
    • Concepcion, F.1    Chen, J.2
  • 47
    • 0037117491 scopus 로고    scopus 로고
    • Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene
    • Gao J., Cheon K., Nusinowitz S., Liu Q., Bei D., Atkins K., et al. Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene. Proc Natl Acad Sci U S A 2002, 99:5698-5703.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 5698-5703
    • Gao, J.1    Cheon, K.2    Nusinowitz, S.3    Liu, Q.4    Bei, D.5    Atkins, K.6
  • 48
    • 78650161159 scopus 로고    scopus 로고
    • Dysfunction of heterotrimeric kinesin-2 in rod photoreceptor cells and the role of opsin mislocalization in rapid cell death
    • Lopes V.S., Jimeno D., Khanobdee K., Song X., Chen B., Nusinowitz S., et al. Dysfunction of heterotrimeric kinesin-2 in rod photoreceptor cells and the role of opsin mislocalization in rapid cell death. Mol Biol Cell 2010, 21:4076-4088.
    • (2010) Mol Biol Cell , vol.21 , pp. 4076-4088
    • Lopes, V.S.1    Jimeno, D.2    Khanobdee, K.3    Song, X.4    Chen, B.5    Nusinowitz, S.6
  • 50
    • 79952446169 scopus 로고    scopus 로고
    • Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model
    • Ito Y., Shimazawa M., Inokuchi Y., Yamanaka H., Tsuruma K., Imamura K., et al. Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model. Eur J Neurosci 2011, 33:843-855.
    • (2011) Eur J Neurosci , vol.33 , pp. 843-855
    • Ito, Y.1    Shimazawa, M.2    Inokuchi, Y.3    Yamanaka, H.4    Tsuruma, K.5    Imamura, K.6
  • 52
    • 78149262655 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization
    • Salminen A., Kauppinen A., Hyttinen J.M., Toropainen E., Kaarniranta K. Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization. Mol Med 2010, 16:535-542.
    • (2010) Mol Med , vol.16 , pp. 535-542
    • Salminen, A.1    Kauppinen, A.2    Hyttinen, J.M.3    Toropainen, E.4    Kaarniranta, K.5
  • 53
    • 36049049392 scopus 로고    scopus 로고
    • IRE1 signaling affects cell fate during the unfolded protein response
    • Lin J.H., Li H., Yasumura D., Cohen H.R., Zhang C., Panning B., et al. IRE1 signaling affects cell fate during the unfolded protein response. Science 2007, 318:944-949.
    • (2007) Science , vol.318 , pp. 944-949
    • Lin, J.H.1    Li, H.2    Yasumura, D.3    Cohen, H.R.4    Zhang, C.5    Panning, B.6
  • 55
    • 77953356504 scopus 로고    scopus 로고
    • S-opsin protein is incompletely modified during N-glycan processing in Rpe65(-/-) mice
    • Sato K., Nakazawa M., Takeuchi K., Mizukoshi S., Ishiguro S. S-opsin protein is incompletely modified during N-glycan processing in Rpe65(-/-) mice. Exp Eye Res 2010, 91:54-62.
    • (2010) Exp Eye Res , vol.91 , pp. 54-62
    • Sato, K.1    Nakazawa, M.2    Takeuchi, K.3    Mizukoshi, S.4    Ishiguro, S.5
  • 56
    • 42549144606 scopus 로고    scopus 로고
    • Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis
    • Rong Y., Distelhorst C.W. Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis. Ann Rev Physiol 2008, 70:73-91.
    • (2008) Ann Rev Physiol , vol.70 , pp. 73-91
    • Rong, Y.1    Distelhorst, C.W.2
  • 57
    • 77149134285 scopus 로고    scopus 로고
    • Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo
    • Dong Y., Zhang M., Liang B., Xie Z., Zhao Z., Asfa S., et al. Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo. Circulation 2010, 121:792-803.
    • (2010) Circulation , vol.121 , pp. 792-803
    • Dong, Y.1    Zhang, M.2    Liang, B.3    Xie, Z.4    Zhao, Z.5    Asfa, S.6
  • 58
    • 34447535286 scopus 로고    scopus 로고
    • Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals
    • Yang J., Pawlyk B., Wen X.H., Adamian M., Soloviev M., Michaud N., et al. Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals. Hum Mol Genet 2007, 16:1017-1029.
    • (2007) Hum Mol Genet , vol.16 , pp. 1017-1029
    • Yang, J.1    Pawlyk, B.2    Wen, X.H.3    Adamian, M.4    Soloviev, M.5    Michaud, N.6


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