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Volumn 30, Issue 37, 2011, Pages 3967-3978

SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis

Author keywords

colorectal neoplasia; cytokinesis; early detection; methylation; SP; Spartin

Indexed keywords

MESSENGER RNA; SPARTIN PROTEIN; SPASTIC PARAPLEGIA 20; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 85027949861     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.109     Document Type: Article
Times cited : (62)

References (46)
  • 2
    • 34248193319 scopus 로고    scopus 로고
    • Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking
    • DOI 10.1091/mbc.E06-09-0833
    • Bakowska JC, Jupille H, Fatheddin P, Puertollano R, Blackstone C. (2007). Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor trafficking. Mol Biol Cell 18: 1683-1692. (Pubitemid 46717550)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.5 , pp. 1683-1692
    • Bakowska, J.C.1    Jupille, H.2    Fatheddin, P.3    Puertollano, R.4    Blackstone, C.5
  • 3
    • 42249086660 scopus 로고    scopus 로고
    • Lack of spartin protein in Troyer syndrome: A loss-of-function disease mechanism?
    • DOI 10.1001/archneur.65.4.520
    • Bakowska JC, Wang H, Xin B, Sumner CJ, Blackstone C. (2008). Lack of spartin protein in Troyer syndrome: a loss-of-function disease mechanism? Arch Neurol 65: 520-524. (Pubitemid 351549962)
    • (2008) Archives of Neurology , vol.65 , Issue.4 , pp. 520-524
    • Bakowska, J.C.1    Wang, H.2    Xin, B.3    Sumner, C.J.4    Blackstone, C.5
  • 4
    • 49549100682 scopus 로고    scopus 로고
    • Silencing of polo-like kinase (Plk) 1 via siRNA causes inhibition of growth and induction of apoptosis in human esophageal cancer cells
    • Bu Y, Yang Z, Li Q, Song F. (2008). Silencing of polo-like kinase (Plk) 1 via siRNA causes inhibition of growth and induction of apoptosis in human esophageal cancer cells. Oncology 74: 198-206.
    • (2008) Oncology , vol.74 , pp. 198-206
    • Bu, Y.1    Yang, Z.2    Li, Q.3    Song, F.4
  • 5
    • 21644443846 scopus 로고    scopus 로고
    • Alix regulates cortical actin and the spatial distribution of endosomes
    • DOI 10.1242/jcs.02382
    • Cabezas A, Bache KG, Brech A, Stenmark H. (2005). Alix regulates cortical actin and the spatial distribution of endosomes. J Cell Sci 118: 2625-2635. (Pubitemid 40932888)
    • (2005) Journal of Cell Science , vol.118 , Issue.12 , pp. 2625-2635
    • Cabezas, A.1    Bache, K.G.2    Brech, A.3    Stenmark, H.4
  • 8
    • 0037381932 scopus 로고    scopus 로고
    • The identification of a conserved domain in both spartin and spastin, mutated in hereditary spastic paraplegia
    • DOI 10.1016/S0888-7543(03)00011-9
    • Ciccarelli FD, Proukakis C, Patel H, Cross H, Azam S, Patton MA et al. (2003). The identification of a conserved domain in both spartin and spastin, mutated in hereditary spastic paraplegia. Genomics 81: 437-441. (Pubitemid 36379166)
    • (2003) Genomics , vol.81 , Issue.4 , pp. 437-441
    • Ciccarelli, F.D.1    Proukakis, C.2    Patel, H.3    Cross, H.4    Azam, S.5    Patton, M.A.6    Bork, P.7    Crosby, A.H.8
  • 9
    • 58149181351 scopus 로고    scopus 로고
    • Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion
    • Connell JW, Lindon C, Luzio JP, Reid E. (2009). Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion. Traffic 10: 42-56.
    • (2009) Traffic , vol.10 , pp. 42-56
    • Connell, J.W.1    Lindon, C.2    Luzio, J.P.3    Reid, E.4
  • 10
    • 67650077151 scopus 로고    scopus 로고
    • Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer
    • Devos T, Tetzner R, Model F, Weiss G, Schuster M, Distler J et al. (2009). Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer. Clin Chem 55: 1337-1346.
    • (2009) Clin Chem , vol.55 , pp. 1337-1346
    • Devos, T.1    Tetzner, R.2    Model, F.3    Weiss, G.4    Schuster, M.5    Distler, J.6
  • 11
    • 64049118343 scopus 로고    scopus 로고
    • A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover
    • Eastman SW, Yassaee M, Bieniasz PD. (2009). A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover. J Cell Biol 184: 881-894.
    • (2009) J Cell Biol , vol.184 , pp. 881-894
    • Eastman, S.W.1    Yassaee, M.2    Bieniasz, P.D.3
  • 12
    • 70349780028 scopus 로고    scopus 로고
    • Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5
    • Edwards TL, Clowes VE, Tsang HT, Connell JW, Sanderson CM, Luzio JP et al. (2009). Endogenous spartin (SPG20) is recruited to endosomes and lipid droplets and interacts with the ubiquitin E3 ligases AIP4 and AIP5. Biochem J 423: 31-39.
    • (2009) Biochem J , vol.423 , pp. 31-39
    • Edwards, T.L.1    Clowes, V.E.2    Tsang, H.T.3    Connell, J.W.4    Sanderson, C.M.5    Luzio, J.P.6
  • 13
    • 5744240094 scopus 로고    scopus 로고
    • Spastin interacts with the centrosomal protein NA14, and is enriched in the spindle pole, the midbody and the distal axon
    • DOI 10.1093/hmg/ddh223
    • Errico A, Claudiani P, D'Addio M, Rugarli EI. (2004). Spastin interacts with the centrosomal protein NA14, and is enriched in the spindle pole, the midbody and the distal axon. Hum Mol Genet 13: 2121-2132. (Pubitemid 39377834)
    • (2004) Human Molecular Genetics , vol.13 , Issue.18 , pp. 2121-2132
    • Errico, A.1    Claudiani, P.2    D'Addio, M.3    Rugarli, E.I.4
  • 14
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • DOI 10.1038/nrg1748
    • Feinberg AP, Ohlsson R, Henikoff S. (2006). The epigenetic progenitor origin of human cancer. Nat Rev Genet 7: 21-33. (Pubitemid 41828945)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.1 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 15
    • 33847638137 scopus 로고    scopus 로고
    • Estimates of the cancer incidence and mortality in Europe in 2006
    • DOI 10.1093/annonc/mdl498
    • Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P. (2007). Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 18: 581-592. (Pubitemid 46359643)
    • (2007) Annals of Oncology , vol.18 , Issue.3 , pp. 581-592
    • Ferlay, J.1    Autier, P.2    Boniol, M.3    Heanue, M.4    Colombet, M.5    Boyle, P.6
  • 16
    • 27144507868 scopus 로고    scopus 로고
    • Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
    • DOI 10.1038/nature04217, PII N04217
    • Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D. (2005). Cytokinesis failure generating tetraploids promotes tumor-igenesis in p53-null cells. Nature 437: 1043-1047. (Pubitemid 41486987)
    • (2005) Nature , vol.437 , Issue.7061 , pp. 1043-1047
    • Fujiwara, T.1    Bandi, M.2    Nitta, M.3    Ivanova, E.V.4    Bronson, R.T.5    Pellman, D.6
  • 17
  • 18
    • 33847266422 scopus 로고    scopus 로고
    • Genomic sweeping for hypermethylated genes
    • DOI 10.1093/bioinformatics/btl620
    • Goh L, Murphy SK, Muhkerjee S, Furey TS. (2007). Genomic sweeping for hypermethylated genes. Bioinformatics 23: 281-288. (Pubitemid 46323149)
    • (2007) Bioinformatics , vol.23 , Issue.3 , pp. 281-288
    • Goh, L.1    Murphy, S.K.2    Muhkerjee, S.3    Furey, T.S.4
  • 20
    • 77952616841 scopus 로고    scopus 로고
    • Spartin activates atrophin-1-interacting protein 4 (AIP 4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets
    • Hooper C, Puttamadappa SS, Loring Z, Shekhtman A, Bakowska JC. (2010). Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets. BMC Biol 8: 72.
    • (2010) BMC Biol , vol.8 , pp. 72
    • Hooper, C.1    Puttamadappa, S.S.2    Loring, Z.3    Shekhtman, A.4    Bakowska, J.C.5
  • 22
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. (2002). The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428. (Pubitemid 34587077)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 23
    • 77349107376 scopus 로고    scopus 로고
    • DNA methylation markers in colorectal cancer
    • Kim MS, Lee J, Sidransky D. (2010). DNA methylation markers in colorectal cancer. Cancer Metastasis Rev 29: 181-206.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 181-206
    • Kim, M.S.1    Lee, J.2    Sidransky, D.3
  • 24
    • 63049098369 scopus 로고    scopus 로고
    • Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays
    • Kron K, Pethe V, Briollais L, Sadikovic B, Ozcelik H, Sunderji A et al. (2009). Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays. PLoS ONE 4: e4830.
    • (2009) PLoS ONE , vol.4
    • Kron, K.1    Pethe, V.2    Briollais, L.3    Sadikovic, B.4    Ozcelik, H.5    Sunderji, A.6
  • 25
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • DOI 10.1038/386623a0
    • Lengauer C, Kinzler KW, Vogelstein B. (1997). Genetic instability in colorectal cancers. Nature 386: 623-627. (Pubitemid 27175430)
    • (1997) Nature , vol.386 , Issue.6625 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 26
    • 34247491523 scopus 로고    scopus 로고
    • DNA Hypermethylation of MAL: A Promising Diagnostic Biomarker for Colorectal Tumors
    • DOI 10.1053/j.gastro.2007.03.003, PII S0016508507004970
    • Lind GE, Ahlquist T, Lothe RA. (2007). DNA hypermethylation of MAL: a promising diagnostic biomarker for colorectal tumors. Gastroenterology 132: 1631-1632. (Pubitemid 46656256)
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1631-1632
    • Lind, G.E.1    Ahlquist, T.2    Lothe, R.A.3
  • 28
    • 33748043331 scopus 로고    scopus 로고
    • The hereditary spastic paraplegia protein spartin localises to mitochondria
    • DOI 10.1111/j.1471-4159.2006.04008.x
    • Lu J, Rashid F, Byrne PC. (2006). The hereditary spastic paraplegia protein spartin localises to mitochondria. J Neurochem 98: 1908-1919. (Pubitemid 44298254)
    • (2006) Journal of Neurochemistry , vol.98 , Issue.6 , pp. 1908-1919
    • Lu, J.1    Rashid, F.2    Byrne, P.C.3
  • 29
    • 70350128630 scopus 로고    scopus 로고
    • Identification of novel spartin-interactors shows spartin is a multifunctional protein
    • Milewska M, McRedmond J, Byrne PC. (2009). Identification of novel spartin-interactors shows spartin is a multifunctional protein. J Neurochem 111: 1022-1030.
    • (2009) J Neurochem , vol.111 , pp. 1022-1030
    • Milewska, M.1    McRedmond, J.2    Byrne, P.C.3
  • 31
    • 0036223382 scopus 로고    scopus 로고
    • Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis
    • DOI 10.1091/mbc.01-09-0467
    • Murata-Hori M, Tatsuka M, Wang YL. (2002). Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis. Mol Biol Cell 13: 1099-1108. (Pubitemid 34309608)
    • (2002) Molecular Biology of the Cell , vol.13 , Issue.4 , pp. 1099-1108
    • Murata-Hori, M.1    Tatsuka, M.2    Wang, Y.-L.3
  • 33
    • 77952752185 scopus 로고    scopus 로고
    • Physiological and physiopathological aspects of connexins and communicating gap junctions in spermatogenesis
    • Pointis G, Gilleron J, Carette D, Segretain D. (2010). Physiological and physiopathological aspects of connexins and communicating gap junctions in spermatogenesis. Philos Trans R Soc Lond B Biol Sci 365: 1607-1620.
    • (2010) Philos Trans R Soc Lond B Biol Sci , vol.365 , pp. 1607-1620
    • Pointis, G.1    Gilleron, J.2    Carette, D.3    Segretain, D.4
  • 34
    • 4644268519 scopus 로고    scopus 로고
    • Troyer syndrome revisited: A clinical and radiological study of a complicated hereditary spastic paraplegia
    • DOI 10.1007/s00415-004-0491-3
    • Proukakis C, Cross H, Patel H, Patton MA, Valentine A, Crosby AH. (2004). Troyer syndrome revisited. A clinical and radiological study of a complicated hereditary spastic paraplegia. J Neurol 251: 1105-1110. (Pubitemid 39297207)
    • (2004) Journal of Neurology , vol.251 , Issue.9 , pp. 1105-1110
    • Proukakis, C.1    Cross, H.2    Patel, H.3    Patton, M.A.4    Valentine, A.5    Crosby, A.H.6
  • 35
    • 77958064894 scopus 로고    scopus 로고
    • SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis
    • Renvoise B, Parker RL, Yang D, Bakowska JC, Hurley JH, Blackstone C. (2010). SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis. Mol Biol Cell 21: 3293-3303.
    • (2010) Mol Biol Cell , vol.21 , pp. 3293-3303
    • Renvoise, B.1    Parker, R.L.2    Yang, D.3    Bakowska, J.C.4    Hurley, J.H.5    Blackstone, C.6
  • 36
    • 33747611457 scopus 로고    scopus 로고
    • Endogenous spartin, mutated in hereditary spastic paraplegia, has a complex subcellular localization suggesting diverse roles in neurons
    • DOI 10.1016/j.yexcr.2006.05.003, PII S0014482706001765
    • Robay D, Patel H, Simpson MA, Brown NA, Crosby AH. (2006). Endogenous spartin, mutated in hereditary spastic paraplegia, has a complex subcellular localization suggesting diverse roles in neurons. Exp Cell Res 312: 2764-2777. (Pubitemid 44262352)
    • (2006) Experimental Cell Research , vol.312 , Issue.15 , pp. 2764-2777
    • Robay, D.1    Patel, H.2    Simpson, M.A.3    Brown, N.A.4    Crosby, A.H.5
  • 37
    • 77950510375 scopus 로고    scopus 로고
    • PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
    • Sagona AP, Nezis IP, Pedersen NM, Liestol K, Poulton J, Rusten TE et al. (2010). PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. Nat Cell Biol 12: 362-371.
    • (2010) Nat Cell Biol , vol.12 , pp. 362-371
    • Sagona, A.P.1    Nezis, I.P.2    Pedersen, N.M.3    Liestol, K.4    Poulton, J.5    Rusten, T.E.6
  • 38
    • 77953128969 scopus 로고    scopus 로고
    • Cytokinesis and cancer
    • Sagona AP, Stenmark H. (2010). Cytokinesis and cancer. FEBS Lett 584: 2652-2661.
    • (2010) FEBS Lett , vol.584 , pp. 2652-2661
    • Sagona, A.P.1    Stenmark, H.2
  • 40
    • 70350343134 scopus 로고    scopus 로고
    • Cytokinetic abscission: Cellular dynamics at the midbody
    • Steigemann P, Gerlich DW. (2009). Cytokinetic abscission: cellular dynamics at the midbody. Trends Cell Biol 19: 606-616.
    • (2009) Trends Cell Biol , vol.19 , pp. 606-616
    • Steigemann, P.1    Gerlich, D.W.2
  • 41
    • 59049101302 scopus 로고    scopus 로고
    • Aurora B-mediated abscission checkpoint protects against tetraploidization
    • Steigemann P, Wurzenberger C, Schmitz MH, Held M, Guizetti J, Maar S et al. (2009). Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell 136: 473-484.
    • (2009) Cell , vol.136 , pp. 473-484
    • Steigemann, P.1    Wurzenberger, C.2    Schmitz, M.H.3    Held, M.4    Guizetti, J.5    Maar, S.6
  • 42
    • 70349579493 scopus 로고    scopus 로고
    • The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling
    • Tsang HT, Edwards TL, Wang X, Connell JW, Davies RJ, Durrington HJ et al. (2009). The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling. Hum Mol Genet 18: 3805-3821.
    • (2009) Hum Mol Genet , vol.18 , pp. 3805-3821
    • Tsang, H.T.1    Edwards, T.L.2    Wang, X.3    Connell, J.W.4    Davies, R.J.5    Durrington, H.J.6
  • 43
    • 0038107491 scopus 로고    scopus 로고
    • Intercellular organelle traffic through cytoplasmic bridges in early spermatids of the rat: Mechanisms of haploid gene product sharing
    • DOI 10.1091/mbc.E02-10-0647
    • Ventela S, Toppari J, Parvinen M. (2003). Intercellular organelle traffic through cytoplasmic bridges in early spermatids of the rat: mechanisms of haploid gene product sharing. Mol Biol Cell 14: 2768-2780. (Pubitemid 36871520)
    • (2003) Molecular Biology of the Cell , vol.14 , Issue.7 , pp. 2768-2780
    • Ventela, S.1    Toppari, J.2    Parvinen, M.3
  • 46
    • 33847355677 scopus 로고    scopus 로고
    • DNA methylation in colorectal cancer - Impact on screening and therapy monitoring modalities?
    • Epigenetic Markers
    • Zitt M, Zitt M, Muller HM. (2007). DNA methylation in colorectal cancer-impact on screening and therapy monitoring modalities? Dis Markers 23: 51-71. (Pubitemid 46333641)
    • (2007) Disease Markers , vol.23 , Issue.1-2 , pp. 51-71
    • Zitt, M.1    Zitt, M.2    Muller, H.M.3


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