Upregulation of cytosolic NADP+-dependent isocitrate dehydrogenase by hyperglycemia protects renal cells against oxidative stress

Molecules and Cells

Volumn 29, Issue 2, 2010, Pages 203-208

  Lee, Soh Hyun ^a   Ha, Sun Ok ^a   Koh, Ho Jin ^a   Kim, Kilsoo ^a   Jeon, Seon Min ^a   Choi, Myung Sook ^a   Kwon, Oh Shin ^a   Huh, Tae Lin ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Diabetic nephropathy; Hyperglycemia; NADPH; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; GLUTATHIONE; ISOCITRATE DEHYDROGENASE (NADP); REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOSOL; DIABETES MELLITUS; DIABETIC NEPHROPATHY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HYPERGLYCEMIA; KIDNEY CORTEX; KIDNEY FIBROSIS; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; UPREGULATION;

MURINAE; MUS; RATTUS;

EID: 85027928696     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10059-009-0183-z     Document Type: Article

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