Id genes are essential for early heart formation

Genes and Development

Volumn 31, Issue 13, 2017, Pages 1325-1338

  Cunningham, Thomas J ^a   Yu, Michael S ^a,b   McKeithan, Wesley L ^a,c   Spiering, Sean ^a   Carrette, Florent ^a   Huang, Chun Teng ^a   Bushway, Paul J ^b   Tierney, Matthew ^a   Albini, Sonia ^a   Giacca, Mauro ^d   Mano, Miguel ^e   Puri, Pier Lorenzo ^a,f   Sacco, Alessandra ^a   Ruiz Lozano, Pilar ^a,g   Riou, Jean Francois ^h   Umbhauer, Muriel ^h   Duester, Gregg ^a   Mercola, Mark ^a,c   Colas, Alexandre R ^a  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY   (United States)

^d INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^e UNIVERSITY OF COIMBRA   (Portugal)

^f IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^g Regencor Inc Incorporated   (United States)

^h SORBONNE UNIVERSITÉ   (France)

Author keywords

Cardiac mesoderm specification; Cardiac progenitors; CRISPR Cas9 mediated quadruple knockout; Heartless; Id proteins; Platform for cardiac disease modeling and drug discovery

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; HEPATOCYTE NUCLEAR FACTOR 3BETA; INHIBITOR OF DIFFERENTIATION PROTEIN; PROTEIN; PROTEIN ID1 4; TRANSCRIPTION FACTOR 7 LIKE 1; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CARDIAC STEM CELL; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; CRISPR CAS SYSTEM; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE; GENE EXPRESSION; GENE SILENCING; HEART DEVELOPMENT; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; ID GENE; MESODERM; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGENERATIVE MEDICINE; REGULATORY MECHANISM; ANIMAL; CELL LINE; CELL LINEAGE; CONGENITAL HEART MALFORMATION; CYTOLOGY; EMBRYOLOGY; EMBRYONIC STEM CELL; GENE EDITING; GENE EXPRESSION REGULATION; GENETICS; HEART; MAMMALIAN EMBRYO; METABOLISM; MUTATION; NONMAMMALIAN EMBRYO; ORGANOGENESIS; PHYSIOLOGY; PLANT SEED; XENOPUS LAEVIS;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; EMBRYO, MAMMALIAN; EMBRYO, NONMAMMALIAN; EMBRYONIC STEM CELLS; GENE EDITING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HEART DEFECTS, CONGENITAL; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEINS; MESODERM; MICE; MUTATION; ORGANOGENESIS; SEEDS; XENOPUS LAEVIS;

EID: 85027567189     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.300400.117     Document Type: Article

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