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Volumn 10, Issue 1, 2017, Pages

Novel immunotherapies for adult patients with B-lineage acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; BLINATUMOMAB; CHIMERIC ANTIGEN RECEPTOR; COLTUXIMAB RAVTANSINE; DENINTUZUMAB MAFODOTIN; EPRATUZUMAB; INOTUZUMAB OZOGAMICIN; OBINUTUZUMAB; OFATUMUMAB; RITUXIMAB;

EID: 85027520890     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-017-0516-x     Document Type: Review
Times cited : (81)

References (81)
  • 1
    • 84872825239 scopus 로고    scopus 로고
    • Dose intensification of daunorubicin and cytarabine during treatment of adult acute lymphoblastic leukemia: Results of Cancer and Leukemia Group B Study 19802
    • 1:CAS:528:DC%2BC38XhvVyntrnO 22744771
    • Stock W, Johnson JL, Stone RM, Kolitz JE, Powell BL, Wetzler M, et al. Dose intensification of daunorubicin and cytarabine during treatment of adult acute lymphoblastic leukemia: results of Cancer and Leukemia Group B Study 19802. Cancer. 2013;119:90-8.
    • (2013) Cancer , vol.119 , pp. 90-98
    • Stock, W.1    Johnson, J.L.2    Stone, R.M.3    Kolitz, J.E.4    Powell, B.L.5    Wetzler, M.6
  • 2
    • 77956240944 scopus 로고    scopus 로고
    • Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC3cXhtFyhsrfI 20660823 2940403
    • Thomas DA, O'Brien S, Faderl S, Garcia-Manero G, Ferrajoli A, Wierda W, et al. Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia. J Clin Oncol. 2010;28:3880-9.
    • (2010) J Clin Oncol , vol.28 , pp. 3880-3889
    • Thomas, D.A.1    O'Brien, S.2    Faderl, S.3    Garcia-Manero, G.4    Ferrajoli, A.5    Wierda, W.6
  • 3
    • 84933505636 scopus 로고    scopus 로고
    • Monoclonal antibodies in acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC2MXht12qu7%2FO 25999456 4548495
    • Jabbour E, O'Brien S, Ravandi F, Kantarjian H. Monoclonal antibodies in acute lymphoblastic leukemia. Blood. 2015;125:4010-6.
    • (2015) Blood , vol.125 , pp. 4010-4016
    • Jabbour, E.1    O'Brien, S.2    Ravandi, F.3    Kantarjian, H.4
  • 4
    • 84875716409 scopus 로고    scopus 로고
    • High-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia
    • 23169518
    • O'Brien S, Schiller G, Lister J, Damon L, Goldberg S, Aulitzky W, et al. High-dose vincristine sulfate liposome injection for advanced, relapsed, and refractory adult Philadelphia chromosome-negative acute lymphoblastic leukemia. J Clin Oncol. 2013;31:676-83.
    • (2013) J Clin Oncol , vol.31 , pp. 676-683
    • O'Brien, S.1    Schiller, G.2    Lister, J.3    Damon, L.4    Goldberg, S.5    Aulitzky, W.6
  • 5
    • 0141482004 scopus 로고    scopus 로고
    • Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia
    • 1:CAS:528:DC%2BD3sXnslykt7Y%3D 12791647
    • Kantarjian H, Gandhi V, Cortes J, Verstovsek S, Du M, Garcia-Manero G, et al. Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia. Blood. 2003;102:2379-86.
    • (2003) Blood , vol.102 , pp. 2379-2386
    • Kantarjian, H.1    Gandhi, V.2    Cortes, J.3    Verstovsek, S.4    Du, M.5    Garcia-Manero, G.6
  • 6
    • 76549108577 scopus 로고    scopus 로고
    • Adverse prognostic significance of CD20 expression in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia
    • 19773266
    • Maury S, Huguet F, Leguay T, Lacombe F, Maynadie M, Girard S, et al. Adverse prognostic significance of CD20 expression in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia. Haematologica. 2010;95:324-8.
    • (2010) Haematologica , vol.95 , pp. 324-328
    • Maury, S.1    Huguet, F.2    Leguay, T.3    Lacombe, F.4    Maynadie, M.5    Girard, S.6
  • 7
    • 84919481075 scopus 로고    scopus 로고
    • Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: Report of a large prospective multicenter trial
    • 1:CAS:528:DC%2BC2MXitFehsA%3D%3D 25359988 4271177
    • Hoelzer D, Walewski J, Dohner H, Viardot A, Hiddemann W, Spiekermann K, et al. Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial. Blood. 2014;124:3870-9.
    • (2014) Blood , vol.124 , pp. 3870-3879
    • Hoelzer, D.1    Walewski, J.2    Dohner, H.3    Viardot, A.4    Hiddemann, W.5    Spiekermann, K.6
  • 8
    • 84880816210 scopus 로고    scopus 로고
    • Outcomes continue to be favorable for de novo Philadelphia chromosome negative B-lymphoblastic leukemia (ALL) after therapy with hyper-CVAD (with or without rituximab) regimen
    • abstract 3572
    • Thomas DA, KH JJ, Faderl S, Jabbour E, Konopleva M, et al. Outcomes continue to be favorable for de novo Philadelphia chromosome negative B-lymphoblastic leukemia (ALL) after therapy with hyper-CVAD (with or without rituximab) regimen. Blood. 2012;120(suppl): abstract 3572.
    • (2012) Blood. , vol.120
    • Thomas, D.A.1    Jj, K.H.2    Faderl, S.3    Jabbour, E.4    Konopleva, M.5
  • 9
    • 84975185519 scopus 로고    scopus 로고
    • Addition of rituximab improves the outcome of adult patients with CD20-positive, Ph-negative, B-cell precursor acute lymphoblastic leukemia (BCP-ALL): Results of the randomized Graall-R 2005 study
    • abstract 1
    • Sébastien Maury SC, Xavier T, Dominik H, Thibaut L, Françoise H, Patrice C, et al. Addition of rituximab improves the outcome of adult patients with CD20-positive, Ph-negative, B-cell precursor acute lymphoblastic leukemia (BCP-ALL): results of the randomized Graall-R 2005 study. Blood. 2015;126(suppl): abstract 1.
    • (2015) Blood. , vol.126
    • Sébastien Maury, S.C.1    Xavier, T.2    Dominik, H.3    Thibaut, L.4    Françoise, H.5    Patrice, C.6
  • 10
    • 84988449072 scopus 로고    scopus 로고
    • Rituximab in B-lineage adult acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC28XhvF2ksrjN 27626518
    • Maury S, Chevret S, Thomas X, Heim D, Leguay T, Huguet F, et al. Rituximab in B-lineage adult acute lymphoblastic leukemia. N Engl J Med. 2016;375:1044-53.
    • (2016) N Engl J Med , vol.375 , pp. 1044-1053
    • Maury, S.1    Chevret, S.2    Thomas, X.3    Heim, D.4    Leguay, T.5    Huguet, F.6
  • 11
    • 84938603207 scopus 로고    scopus 로고
    • Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia
    • 26170206 4522086 Jul
    • Rai KR. Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia. J Hematol Oncol. 2015 Jul;8:85.
    • (2015) J Hematol Oncol , vol.8 , pp. 85
    • Rai, K.R.1
  • 12
    • 84955331603 scopus 로고    scopus 로고
    • Obinutuzumab (GA101) compared to rituximab significantly enhances cell death and antibody-dependent cytotoxicity and improves overall survival against CD20(+) rituximab-sensitive/-resistant Burkitt lymphoma (BL) and precursor B-acute lymphoblastic leukaemia (pre-B-ALL): Potential targeted therapy in patients with poor risk CD20(+) BL and pre-B-ALL
    • 1:CAS:528:DC%2BC2MXhvVyiu7%2FE 26471982
    • Awasthi A, Ayello J, Van de Ven C, Elmacken M, Sabulski A, Barth MJ, et al. Obinutuzumab (GA101) compared to rituximab significantly enhances cell death and antibody-dependent cytotoxicity and improves overall survival against CD20(+) rituximab-sensitive/-resistant Burkitt lymphoma (BL) and precursor B-acute lymphoblastic leukaemia (pre-B-ALL): potential targeted therapy in patients with poor risk CD20(+) BL and pre-B-ALL. Br J Haematol. 2015;171:763-75.
    • (2015) Br J Haematol , vol.171 , pp. 763-775
    • Awasthi, A.1    Ayello, J.2    Van De Ven, C.3    Elmacken, M.4    Sabulski, A.5    Barth, M.J.6
  • 13
    • 85027490225 scopus 로고    scopus 로고
    • Phase II Study of the Frontline Hyper-CVAD in Combination with Ofatumumab for Adult Patients (pts) with CD-20 Positive Acute Lymphoblastic Leukemia (ALL)
    • abstract 1295
    • Koji SP, Hagop MK, Deborah AT, Maria RK, Guillermo GM, Rebecca G, et al. Phase II Study of the Frontline Hyper-CVAD in Combination with Ofatumumab for Adult Patients (pts) with CD-20 Positive Acute Lymphoblastic Leukemia (ALL). Blood 2015;126(suppl): abstract 1295.
    • (2015) Blood , vol.126
    • Koji, S.P.1    Hagop, M.K.2    Deborah, A.T.3    Maria, R.K.4    Guillermo, G.M.5    Rebecca, G.6
  • 14
    • 85027516915 scopus 로고    scopus 로고
    • Frontline Ofatumumab in Combination with Hyper-CVAD for Adult Patients with CD-20 Positive Acute Lymphoblastic Leukemia (ALL): Interim Result of a Phase II Clinical Trial
    • abstract 2783
    • Koji SH, Farhad R, Naval D, Tapan MK, Rita BK, Yesid A, et al. Frontline Ofatumumab in Combination with Hyper-CVAD for Adult Patients with CD-20 Positive Acute Lymphoblastic Leukemia (ALL): Interim Result of a Phase II Clinical Trial. Blood. 2016;128(suppl): abstract 2783.
    • (2016) Blood. , vol.128
    • Koji, S.H.1    Farhad, R.2    Naval, D.3    Tapan, M.K.4    Rita, B.K.5    Yesid, A.6
  • 15
    • 85006866942 scopus 로고    scopus 로고
    • A Review of Obinutuzumab (GA101), a Novel Type II Anti-CD20 Monoclonal Antibody, for the Treatment of Patients with B-Cell Malignancies
    • 1:CAS:528:DC%2BC28XitFGisrrK 28004361
    • Tobinai K, Klein C, Oya N, Fingerle-Rowson G. A Review of Obinutuzumab (GA101), a Novel Type II Anti-CD20 Monoclonal Antibody, for the Treatment of Patients with B-Cell Malignancies. Adv Ther. 2017;34:324-56.
    • (2017) Adv Ther , vol.34 , pp. 324-356
    • Tobinai, K.1    Klein, C.2    Oya, N.3    Fingerle-Rowson, G.4
  • 16
    • 80054095609 scopus 로고    scopus 로고
    • SAR3419: An anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies
    • 1:CAS:528:DC%2BC3MXhtlSksr3O 22003072
    • Blanc V, Bousseau A, Caron A, Carrez C, Lutz RJ, Lambert JM. SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies. Clin Cancer Res. 2011;17:6448-58.
    • (2011) Clin Cancer Res , vol.17 , pp. 6448-6458
    • Blanc, V.1    Bousseau, A.2    Caron, A.3    Carrez, C.4    Lutz, R.J.5    Lambert, J.M.6
  • 17
    • 84864544136 scopus 로고    scopus 로고
    • Phase i multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma
    • 1:CAS:528:DC%2BC38XhsFertrzJ 22753910
    • Younes A, Kim S, Romaguera J, Copeland A, Farial Sde C, Kwak LW, et al. Phase I multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma. J Clin Oncol. 2012;30:2776-82.
    • (2012) J Clin Oncol , vol.30 , pp. 2776-2782
    • Younes, A.1    Kim, S.2    Romaguera, J.3    Copeland, A.4    Farial Sde, C.5    Kwak, L.W.6
  • 18
    • 84877100125 scopus 로고    scopus 로고
    • The anti-CD19 antibody-drug conjugate SAR3419 prevents hematolymphoid relapse postinduction therapy in preclinical models of pediatric acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC3sXlsVCmsLY%3D 23426279 3618498
    • Carol H, Szymanska B, Evans K, Boehm I, Houghton PJ, Smith MA, et al. The anti-CD19 antibody-drug conjugate SAR3419 prevents hematolymphoid relapse postinduction therapy in preclinical models of pediatric acute lymphoblastic leukemia. Clin Cancer Res. 2013;19:1795-805.
    • (2013) Clin Cancer Res , vol.19 , pp. 1795-1805
    • Carol, H.1    Szymanska, B.2    Evans, K.3    Boehm, I.4    Houghton, P.J.5    Smith, M.A.6
  • 19
    • 84958922276 scopus 로고    scopus 로고
    • A Phase II Study of Coltuximab Ravtansine (SAR3419) Monotherapy in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia
    • 26775883
    • Kantarjian HM, Lioure B, Kim SK, Atallah E, Leguay T, Kelly K, et al. A Phase II Study of Coltuximab Ravtansine (SAR3419) Monotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia. Clin Lymphoma Myeloma Leuk. 2016;16:139-45.
    • (2016) Clin Lymphoma Myeloma Leuk , vol.16 , pp. 139-145
    • Kantarjian, H.M.1    Lioure, B.2    Kim, S.K.3    Atallah, E.4    Leguay, T.5    Kelly, K.6
  • 20
    • 85027533881 scopus 로고    scopus 로고
    • Interim analysis of a phase 1 study of the antibody-drug conjugate SGN-CD19A in relapsed or refractory B-lineage acute leukemia and highly aggressive lymphoma
    • abstract 963
    • Amir TF, Tanya MT, Maureen MO, Daniel JD, Bijal DS, Todd MC, et al. Interim analysis of a phase 1 study of the antibody-drug conjugate SGN-CD19A in relapsed or refractory B-lineage acute leukemia and highly aggressive lymphoma. Blood. 2014;124(suppl): abstract 963.
    • (2014) Blood. , vol.124
    • Amir, T.F.1    Tanya, M.T.2    Maureen, M.O.3    Daniel, J.D.4    Bijal, D.S.5    Todd, M.C.6
  • 21
    • 84938628792 scopus 로고    scopus 로고
    • Blinatumomab: A bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia
    • 26337639 4558758
    • Wu J, Fu J, Zhang M, Liu D. Blinatumomab: a bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia. J Hematol Oncol. 2015;8:104.
    • (2015) J Hematol Oncol , vol.8 , pp. 104
    • Wu, J.1    Fu, J.2    Zhang, M.3    Liu, D.4
  • 22
    • 84950989868 scopus 로고    scopus 로고
    • Bispecific antibodies and their applications
    • 26692321 4687327
    • Fan G, Wang Z, Hao M, Li J. Bispecific antibodies and their applications. J Hematol Oncol. 2015;8:130.
    • (2015) J Hematol Oncol , vol.8 , pp. 130
    • Fan, G.1    Wang, Z.2    Hao, M.3    Li, J.4
  • 23
    • 84863522243 scopus 로고    scopus 로고
    • Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab
    • 1:CAS:528:DC%2BC38XhtFSgtL7F 22592608
    • Klinger M, Brandl C, Zugmaier G, Hijazi Y, Bargou RC, Topp MS, et al. Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab. Blood. 2012;119:6226-33.
    • (2012) Blood , vol.119 , pp. 6226-6233
    • Klinger, M.1    Brandl, C.2    Zugmaier, G.3    Hijazi, Y.4    Bargou, R.C.5    Topp, M.S.6
  • 24
    • 79959312575 scopus 로고    scopus 로고
    • Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival
    • 1:CAS:528:DC%2BC3MXpsVyqtr8%3D 21576633
    • Topp MS, Kufer P, Gokbuget N, Goebeler M, Klinger M, Neumann S, et al. Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival. J Clin Oncol. 2011;29:2493-8.
    • (2011) J Clin Oncol , vol.29 , pp. 2493-2498
    • Topp, M.S.1    Kufer, P.2    Gokbuget, N.3    Goebeler, M.4    Klinger, M.5    Neumann, S.6
  • 25
    • 84959468203 scopus 로고    scopus 로고
    • Potential for bispecific T-cell engagers: Role of blinatumomab in acute lymphoblastic leukemia
    • 26937176 4762579
    • Le Jeune C, Thomas X. Potential for bispecific T-cell engagers: role of blinatumomab in acute lymphoblastic leukemia. Drug Des Devel Ther. 2016;10:757-65.
    • (2016) Drug des Devel Ther , vol.10 , pp. 757-765
    • Le Jeune, C.1    Thomas, X.2
  • 26
    • 85027501791 scopus 로고    scopus 로고
    • Long-Term Outcomes after Blinatumomab Treatment: Follow-up of a Phase 2 Study in Patients (Pts) with Minimal Residual Disease (MRD) Positive B-Cell Precursor Acute Lymphoblastic Leukemia (ALL)
    • abstract 680
    • Nicola GH, Massimiliano B, Albrecht R, Carlos G, Christoph F, Helmut D, et al. Long-Term Outcomes after Blinatumomab Treatment: Follow-up of a Phase 2 Study in Patients (Pts) with Minimal Residual Disease (MRD) Positive B-Cell Precursor Acute Lymphoblastic Leukemia (ALL). Blood. 2015;126(suppl): abstract 680.
    • (2015) Blood. , vol.126
    • Nicola, G.H.1    Massimiliano, B.2    Albrecht, R.3    Carlos, G.4    Christoph, F.5    Helmut, D.6
  • 27
    • 84916639631 scopus 로고    scopus 로고
    • Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC2MXit1entr8%3D 25385737
    • Topp MS, Gokbuget N, Zugmaier G, Klappers P, Stelljes M, Neumann S, et al. Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia. J Clin Oncol. 2014;32:4134-40.
    • (2014) J Clin Oncol , vol.32 , pp. 4134-4140
    • Topp, M.S.1    Gokbuget, N.2    Zugmaier, G.3    Klappers, P.4    Stelljes, M.5    Neumann, S.6
  • 28
    • 84926099033 scopus 로고    scopus 로고
    • Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: A multicentre, single-arm, phase 2 study
    • 1:CAS:528:DC%2BC2MXht1yhsb0%3D 25524800
    • Topp MS, Gokbuget N, Stein AS, Zugmaier G, O'Brien S, Bargou RC, et al. Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study. Lancet Oncol. 2015;16:57-66.
    • (2015) Lancet Oncol , vol.16 , pp. 57-66
    • Topp, M.S.1    Gokbuget, N.2    Stein, A.S.3    Zugmaier, G.4    O'Brien, S.5    Bargou, R.C.6
  • 29
    • 84879387212 scopus 로고    scopus 로고
    • CD19 expression in acute leukemia is not restricted to the cytogenetically aberrant populations
    • 1:CAS:528:DC%2BC3sXpvVygs78%3D 23193950
    • Francis J, Dharmadhikari AV, Sait SN, Deeb G, Wallace PK, Thompson JE, et al. CD19 expression in acute leukemia is not restricted to the cytogenetically aberrant populations. Leuk Lymphoma. 2013;54:1517-20.
    • (2013) Leuk Lymphoma , vol.54 , pp. 1517-1520
    • Francis, J.1    Dharmadhikari, A.V.2    Sait, S.N.3    Deeb, G.4    Wallace, P.K.5    Thompson, J.E.6
  • 30
    • 84929868959 scopus 로고    scopus 로고
    • Crucial role of regulatory T cells in predicting the outcome of the T cell engaging antibody blinatumomab in relapsed and refractory B precursor ALL patients
    • abstract 2291
    • Duell J, Dittrich M, Bedke T, Mueller T, Rasche L, Dandekar T, et al. Crucial role of regulatory T cells in predicting the outcome of the T cell engaging antibody blinatumomab in relapsed and refractory B precursor ALL patients. Blood. 2014;124(suppl): abstract 2291.
    • (2014) Blood. , vol.124
    • Duell, J.1    Dittrich, M.2    Bedke, T.3    Mueller, T.4    Rasche, L.5    Dandekar, T.6
  • 31
    • 84943302629 scopus 로고    scopus 로고
    • Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab
    • 26449653 4599591
    • Kohnke T, Krupka C, Tischer J, Knosel T, Subklewe M. Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab. J Hematol Oncol. 2015;8:111.
    • (2015) J Hematol Oncol , vol.8 , pp. 111
    • Kohnke, T.1    Krupka, C.2    Tischer, J.3    Knosel, T.4    Subklewe, M.5
  • 32
    • 84971280558 scopus 로고    scopus 로고
    • Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy
    • 27234522 4884396
    • Ma W, Gilligan BM, Yuan J, Li T. Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy. J Hematol Oncol. 2016;9:47.
    • (2016) J Hematol Oncol , vol.9 , pp. 47
    • Ma, W.1    Gilligan, B.M.2    Yuan, J.3    Li, T.4
  • 33
    • 84942853133 scopus 로고    scopus 로고
    • Redirection of CD4+ and CD8+ T lymphocytes via an anti-CD3 × anti-CD19 bi-specific antibody combined with cytosine arabinoside and the efficient lysis of patient-derived B-ALL cells
    • 26444983 4596481 Oct
    • Fan D, Li W, Yang Y, Zhang X, Zhang Q, Yan Y, et al. Redirection of CD4+ and CD8+ T lymphocytes via an anti-CD3 × anti-CD19 bi-specific antibody combined with cytosine arabinoside and the efficient lysis of patient-derived B-ALL cells. J Hematol Oncol. 2015 Oct;8:108.
    • (2015) J Hematol Oncol , vol.8 , pp. 108
    • Fan, D.1    Li, W.2    Yang, Y.3    Zhang, X.4    Zhang, Q.5    Yan, Y.6
  • 34
    • 12444270688 scopus 로고    scopus 로고
    • Epratuzumab, a humanized monoclonal antibody targeting CD22: Characterization of in vitro properties
    • Carnahan J, Wang P, Kendall R, Chen C, Hu S, Boone T, et al. Epratuzumab, a humanized monoclonal antibody targeting CD22: characterization of in vitro properties. Clin Cancer Res. 2003;9(suppl):3982s-3990s.
    • (2003) Clin Cancer Res. , vol.9 , pp. 3982s-3990s
    • Carnahan, J.1    Wang, P.2    Kendall, R.3    Chen, C.4    Hu, S.5    Boone, T.6
  • 35
    • 84964499378 scopus 로고    scopus 로고
    • Engagement of CD22 on B cells with the monoclonal antibody epratuzumab stimulates the phosphorylation of upstream inhibitory signals of the B cell receptor
    • 27125377 4882304
    • Lumb S, Fleischer SJ, Wiedemann A, Daridon C, Maloney A, Shock A, et al. Engagement of CD22 on B cells with the monoclonal antibody epratuzumab stimulates the phosphorylation of upstream inhibitory signals of the B cell receptor. J Cell Commun Signal. 2016;10:143-51.
    • (2016) J Cell Commun Signal , vol.10 , pp. 143-151
    • Lumb, S.1    Fleischer, S.J.2    Wiedemann, A.3    Daridon, C.4    Maloney, A.5    Shock, A.6
  • 36
    • 84859159818 scopus 로고    scopus 로고
    • Reinduction chemoimmunotherapy with epratuzumab in relapsed acute lymphoblastic leukemia (ALL) in children, adolescents and young adults: Results from Children's Oncology Group (COG) study
    • abstract 573
    • Raetz EA CM, Borowitz MJ. Reinduction chemoimmunotherapy with epratuzumab in relapsed acute lymphoblastic leukemia (ALL) in children, adolescents and young adults: results from Children's Oncology Group (COG) study. Blood. 2011;118(suppl): abstract 573.
    • (2011) Blood. , vol.118
    • Raetz, E.A.C.M.1    Borowitz, M.J.2
  • 37
    • 84899493381 scopus 로고    scopus 로고
    • SWOG S0910: A phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia
    • 1:CAS:528:DC%2BC2cXmvF2rtb8%3D 24579885 4209396
    • Advani AS, McDonough S, Coutre S, Wood B, Radich J, Mims M, et al. SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia. Br J Haematol. 2014;165:504-9.
    • (2014) Br J Haematol , vol.165 , pp. 504-509
    • Advani, A.S.1    McDonough, S.2    Coutre, S.3    Wood, B.4    Radich, J.5    Mims, M.6
  • 38
    • 85027493987 scopus 로고    scopus 로고
    • Hyper-CVAD plus epratuzumab as salvage regimen for younger relapsed/refractory CD22+ B acute lymphoblastic leukemia (ALL) patients: Results of the Phase 2 Prospective Cheprall Study
    • abstract 4018
    • Patrice SC, Françoise H, Emmanuel R, Xavier T, Thibaut L, Tony M, et al. Hyper-CVAD plus epratuzumab as salvage regimen for younger relapsed/refractory CD22+ B acute lymphoblastic leukemia (ALL) patients: results of the Phase 2 Prospective Cheprall Study. Blood. 2016;128(suppl): abstract 4018.
    • (2016) Blood. , vol.128
    • Patrice, S.C.1    Françoise, H.2    Emmanuel, R.3    Xavier, T.4    Thibaut, L.5    Tony, M.6
  • 39
    • 84862555569 scopus 로고    scopus 로고
    • Patient adherence to tyrosine kinase inhibitor therapy in chronic myeloid leukemia
    • 22473898
    • Jabbour EJ, Kantarjian H, Eliasson L, Cornelison AM, Marin D. Patient adherence to tyrosine kinase inhibitor therapy in chronic myeloid leukemia. Am J Hematol. 2012;87:687-91.
    • (2012) Am J Hematol , vol.87 , pp. 687-691
    • Jabbour, E.J.1    Kantarjian, H.2    Eliasson, L.3    Cornelison, A.M.4    Marin, D.5
  • 40
    • 84880574025 scopus 로고    scopus 로고
    • Results of inotuzumab ozogamicin, a CD22 monoclonal antibody, in refractory and relapsed acute lymphocytic leukemia
    • 1:CAS:528:DC%2BC3sXhtFGmtrnK 23633004 3720844
    • Kantarjian H, Thomas D, Jorgensen J, Kebriaei P, Jabbour E, Rytting M, et al. Results of inotuzumab ozogamicin, a CD22 monoclonal antibody, in refractory and relapsed acute lymphocytic leukemia. Cancer. 2013;119:2728-36.
    • (2013) Cancer , vol.119 , pp. 2728-2736
    • Kantarjian, H.1    Thomas, D.2    Jorgensen, J.3    Kebriaei, P.4    Jabbour, E.5    Rytting, M.6
  • 41
    • 84984677465 scopus 로고    scopus 로고
    • Inotuzumab ozogamicin versus standard therapy for acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC28XhvF2ks7%2FI 27292104
    • Kantarjian HM, DeAngelo DJ, Stelljes M, Martinelli G, Liedtke M, Stock W, et al. Inotuzumab ozogamicin versus standard therapy for acute lymphoblastic leukemia. N Engl J Med. 2016;375:740-53.
    • (2016) N Engl J Med , vol.375 , pp. 740-753
    • Kantarjian, H.M.1    DeAngelo, D.J.2    Stelljes, M.3    Martinelli, G.4    Liedtke, M.5    Stock, W.6
  • 42
    • 85027516915 scopus 로고    scopus 로고
    • Phase II study of the salvage mini-hyper-CVD in combination with inotuzumab ozogamicin (INO) for adult patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL)
    • abstract 1606
    • Koji SE, Susan MO, Farhad R, Deborah AT, Tapan MK, Guillermo GM, et al. Phase II study of the salvage mini-hyper-CVD in combination with inotuzumab ozogamicin (INO) for adult patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL). Blood. 2016;128(suppl): abstract 1606.
    • (2016) Blood. , vol.128
    • Koji, S.E.1    Susan, M.O.2    Farhad, R.3    Deborah, A.T.4    Tapan, M.K.5    Guillermo, G.M.6
  • 43
    • 85027493926 scopus 로고    scopus 로고
    • Inotuzumab ozogamicin in combination with low-intensity chemotherapy (mini-hyper-CVD) as frontline therapy for older patients with acute lymphoblastic leukemia (ALL): Interim result of a phase II clinical trial
    • abstract 588
    • Koji SE, Susan MO, Farhad R, Deborah AT, Tapan MK, Guillermo GM, et al. Inotuzumab ozogamicin in combination with low-intensity chemotherapy (mini-hyper-CVD) as frontline therapy for older patients with acute lymphoblastic leukemia (ALL): interim result of a phase II clinical trial. blood;128(suppl): abstract 588.
    • Blood , vol.128
    • Koji, S.E.1    Susan, M.O.2    Farhad, R.3    Deborah, A.T.4    Tapan, M.K.5    Guillermo, G.M.6
  • 44
    • 85027496786 scopus 로고    scopus 로고
    • Alemtuzumab can be incorporated into front-line therapy of adult acute lymphoblastic leukemia (ALL): Final phase i results of a cancer and leukemia group B study (CALGB 10102)
    • abstract 838
    • Wendy SB, Gerard L, Ravi V, John CB, Bayard LP, Meir W, et al. Alemtuzumab can be incorporated into front-line therapy of adult acute lymphoblastic leukemia (ALL): final phase I results of a cancer and leukemia group B study (CALGB 10102). Blood. 2009;114(suppl): abstract 838.
    • (2009) Blood. , vol.114
    • Wendy, S.B.1    Gerard, L.2    Ravi, V.3    John, C.B.4    Bayard, L.P.5    Meir, W.6
  • 45
    • 84884820093 scopus 로고    scopus 로고
    • Administration of alemtuzumab and G-CSF to adults with relapsed or refractory acute lymphoblastic leukemia: Results of a phase II study
    • 1:CAS:528:DC%2BC3sXhsFGgtrrM 23738686
    • Gorin NC, Isnard F, Garderet L, Ikhlef S, Corm S, Quesnel B, et al. Administration of alemtuzumab and G-CSF to adults with relapsed or refractory acute lymphoblastic leukemia: results of a phase II study. Eur J Haematol. 2013;91:315-21.
    • (2013) Eur J Haematol , vol.91 , pp. 315-321
    • Gorin, N.C.1    Isnard, F.2    Garderet, L.3    Ikhlef, S.4    Corm, S.5    Quesnel, B.6
  • 47
    • 84899631361 scopus 로고    scopus 로고
    • Antibody-modified T cells: CARs take the front seat for hematologic malignancies
    • 1:CAS:528:DC%2BC2cXnvFWls7w%3D 24578504 3999751
    • Maus MV, Grupp SA, Porter DL, June CH. Antibody-modified T cells: CARs take the front seat for hematologic malignancies. Blood. 2014;123:2625-35.
    • (2014) Blood , vol.123 , pp. 2625-2635
    • Maus, M.V.1    Grupp, S.A.2    Porter, D.L.3    June, C.H.4
  • 48
    • 34848842554 scopus 로고    scopus 로고
    • Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts
    • 1:CAS:528:DC%2BD2sXhtVCitLzL 17855649
    • Brentjens RJ, Santos E, Nikhamin Y, Yeh R, Matsushita M, La Perle K, et al. Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts. Clin Cancer Res. 2007;13:5426-35.
    • (2007) Clin Cancer Res , vol.13 , pp. 5426-5435
    • Brentjens, R.J.1    Santos, E.2    Nikhamin, Y.3    Yeh, R.4    Matsushita, M.5    La Perle, K.6
  • 49
    • 84876050411 scopus 로고    scopus 로고
    • CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC3sXmsVOjsrg%3D 23585892 3621858
    • Davila ML, Kloss CC, Gunset G, Sadelain M. CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia. PLoS One. 2013;8:e61338.
    • (2013) PLoS One , vol.8 , pp. e61338
    • Davila, M.L.1    Kloss, C.C.2    Gunset, G.3    Sadelain, M.4
  • 50
    • 84982181799 scopus 로고    scopus 로고
    • Predominant cerebral cytokine release syndrome in CD19-directed chimeric antigen receptor-modified T cell therapy
    • 27526682 4986179
    • Hu Y, Sun J, Wu Z, Yu J, Cui Q, Pu C, et al. Predominant cerebral cytokine release syndrome in CD19-directed chimeric antigen receptor-modified T cell therapy. J Hematol Oncol. 2016;9:70.
    • (2016) J Hematol Oncol , vol.9 , pp. 70
    • Hu, Y.1    Sun, J.2    Wu, Z.3    Yu, J.4    Cui, Q.5    Pu, C.6
  • 51
    • 84908073316 scopus 로고    scopus 로고
    • Chimeric antigen receptor T cells for sustained remissions in leukemia
    • 1:CAS:528:DC%2BC2cXitVSls73K 25317870 4267531
    • Maude SL, Frey N, Shaw PA, Aplenc R, Barrett DM, Bunin NJ, et al. Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med. 2014;371:1507-17.
    • (2014) N Engl J Med , vol.371 , pp. 1507-1517
    • Maude, S.L.1    Frey, N.2    Shaw, P.A.3    Aplenc, R.4    Barrett, D.M.5    Bunin, N.J.6
  • 52
    • 84923019006 scopus 로고    scopus 로고
    • T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: A phase 1 dose-escalation trial
    • 1:CAS:528:DC%2BC2cXhslGjtLbM 25319501
    • Lee DW, Kochenderfer JN, Stetler-Stevenson M, Cui YK, Delbrook C, Feldman SA, et al. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial. Lancet. 2015;385:517-28.
    • (2015) Lancet , vol.385 , pp. 517-528
    • Lee, D.W.1    Kochenderfer, J.N.2    Stetler-Stevenson, M.3    Cui, Y.K.4    Delbrook, C.5    Feldman, S.A.6
  • 53
    • 84976287948 scopus 로고    scopus 로고
    • Implications of minimal residual disease negative complete remission (MRD-CR) and allogeneic stem cell transplant on safety and clinical outcome of CD19-targeted 19-28z CAR modified T cells in adult patients with relapsed, refractory B-cell ALL
    • abstract 682
    • Jae H, Park IR, Wang X, Yvette B, Terence P, Halton E, et al. Implications of minimal residual disease negative complete remission (MRD-CR) and allogeneic stem cell transplant on safety and clinical outcome of CD19-targeted 19-28z CAR modified T cells in adult patients with relapsed, refractory B-cell ALL. Blood. 2015;126(suppl): abstract 682.
    • (2015) Blood. , vol.126
    • Jae, H.1    Park, I.R.2    Wang, X.3    Yvette, B.4    Terence, P.5    Halton, E.6
  • 54
    • 85027515256 scopus 로고    scopus 로고
    • Long-Term Outcomes Following CD19 CAR T Cell Therapy for B-ALL Are Superior in Patients Receiving a Fludarabine/Cyclophosphamide Preparative Regimen and Post-CAR Hematopoietic Stem Cell Transplantation
    • abstract 218
    • Lee DW, Yuan CM, Shah NN, Delbrook C, Yates B, Zhang H, et al. Long-Term Outcomes Following CD19 CAR T Cell Therapy for B-ALL Are Superior in Patients Receiving a Fludarabine/Cyclophosphamide Preparative Regimen and Post-CAR Hematopoietic Stem Cell Transplantation. Blood. 2016;128(suppl): abstract 218.
    • (2016) Blood. , vol.128
    • Lee, D.W.1    Yuan, C.M.2    Shah, N.N.3    Delbrook, C.4    Yates, B.5    Zhang, H.6
  • 55
    • 85027522591 scopus 로고    scopus 로고
    • High rates of minimal residual disease-negative (MRD-) complete responses (CR) in adult and pediatric and patients with relapsed/refractory acute lymphoblastic leukemia (R/R ALL) treated with KTE-C19 (anti-CD19 chimeric antigen receptor [CAR] T cells): Preliminary results of the ZUMA-3 and ZUMA-4 trials
    • abstract 2803
    • Shah B, Sender LS, Lee DW, Castro JE, Wierda WG, Dietz AC, et al. High rates of minimal residual disease-negative (MRD-) complete responses (CR) in adult and pediatric and patients with relapsed/refractory acute lymphoblastic leukemia (R/R ALL) treated with KTE-C19 (anti-CD19 chimeric antigen receptor [CAR] T cells): preliminary results of the ZUMA-3 and ZUMA-4 trials. Blood. 2016;128(suppl): abstract 2803.
    • (2016) Blood. , vol.128
    • Shah, B.1    Sender, L.S.2    Lee, D.W.3    Castro, J.E.4    Wierda, W.G.5    Dietz, A.C.6
  • 56
    • 84975172606 scopus 로고    scopus 로고
    • Durable remissions in children with relapsed/refractory ALL treated with T cells engineered with a CD19-targeted chimeric antigen receptor (CTL019)
    • abstract 681
    • Grupp SA, Shaw PA, Aplenc R, Barrett DM, Callahan C, Lacey SF, et al. Durable remissions in children with relapsed/refractory ALL treated with T cells engineered with a CD19-targeted chimeric antigen receptor (CTL019). Blood. 2015;126(suppl): abstract 681.
    • (2015) Blood. , vol.126
    • Grupp, S.A.1    Shaw, P.A.2    Aplenc, R.3    Barrett, D.M.4    Callahan, C.5    Lacey, S.F.6
  • 57
    • 85015622033 scopus 로고    scopus 로고
    • Analysis of a global registration trial of the efficacy and safety of CTL019 in pediatric and young adults with relapsed/refractory acute lymphoblastic leukemia (ALL)
    • abstract 221
    • Grupp SA, Buechner J, Bittencourt H, Maude SL, Verneris MR, Myers GD, et al. Analysis of a global registration trial of the efficacy and safety of CTL019 in pediatric and young adults with relapsed/refractory acute lymphoblastic leukemia (ALL). Blood. 2016;128(suppl): abstract 221.
    • (2016) Blood. , vol.128
    • Grupp, S.A.1    Buechner, J.2    Bittencourt, H.3    Maude, S.L.4    Verneris, M.R.5    Myers, G.D.6
  • 58
    • 85015649864 scopus 로고    scopus 로고
    • Efficacy and safety of CTL019 in the first US phase II multicenter trial in pediatric relapsed/refractory acute lymphoblastic leukemia: Results of an interim analysis
    • abstract 2801
    • Maude SL, Boyer MW, Grupp SA, Davies SM, Phillips CL, Verneris MR, et al. Efficacy and safety of CTL019 in the first US phase II multicenter trial in pediatric relapsed/refractory acute lymphoblastic leukemia: results of an interim analysis. Blood. 2016;128(suppl): abstract 2801.
    • (2016) Blood. , vol.128
    • Maude, S.L.1    Boyer, M.W.2    Grupp, S.A.3    Davies, S.M.4    Phillips, C.L.5    Verneris, M.R.6
  • 59
    • 85010711853 scopus 로고    scopus 로고
    • Allogeneic CD19-CAR-T cell infusion after allogeneic hematopoietic stem cell transplantation in B cell malignancies
    • 28143567 5282795 Jan
    • Liu J, Zhong JF, Zhang X, Zhang C. Allogeneic CD19-CAR-T cell infusion after allogeneic hematopoietic stem cell transplantation in B cell malignancies. J Hematol Oncol. 2017 Jan;10(1):35.
    • (2017) J Hematol Oncol , vol.10 , Issue.1 , pp. 35
    • Liu, J.1    Zhong, J.F.2    Zhang, X.3    Zhang, C.4
  • 60
    • 84890827981 scopus 로고    scopus 로고
    • Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation
    • 1:CAS:528:DC%2BC3sXhvFOqsr7P 24055823 3862276
    • Kochenderfer JN, Dudley ME, Carpenter RO, Kassim SH, Rose JJ, Telford WG, et al. Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation. Blood. 2013;122:4129-39.
    • (2013) Blood , vol.122 , pp. 4129-4139
    • Kochenderfer, J.N.1    Dudley, M.E.2    Carpenter, R.O.3    Kassim, S.H.4    Rose, J.J.5    Telford, W.G.6
  • 61
    • 84887821770 scopus 로고    scopus 로고
    • Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: A phase 1 study
    • 1:CAS:528:DC%2BC3sXhslejurnN 24030379 3811171
    • Cruz CR, Micklethwaite KP, Savoldo B, Ramos CA, Lam S, Ku S, et al. Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood. 2013;122:2965-73.
    • (2013) Blood , vol.122 , pp. 2965-2973
    • Cruz, C.R.1    Micklethwaite, K.P.2    Savoldo, B.3    Ramos, C.A.4    Lam, S.5    Ku, S.6
  • 62
    • 84963594644 scopus 로고    scopus 로고
    • Allogeneic T cells that express an anti-CD19 chimeric antigen receptor induce remissions of B-cell malignancies that progress after allogeneic hematopoietic stem-cell transplantation without causing graft-versus-host disease
    • 1:CAS:528:DC%2BC28XitFCksLnE 26811520 4872017
    • Brudno JN, Somerville RP, Shi V, Rose JJ, Halverson DC, Fowler DH, et al. Allogeneic T cells that express an anti-CD19 chimeric antigen receptor induce remissions of B-cell malignancies that progress after allogeneic hematopoietic stem-cell transplantation without causing graft-versus-host disease. J Clin Oncol. 2016;34:1112-21.
    • (2016) J Clin Oncol , vol.34 , pp. 1112-1121
    • Brudno, J.N.1    Somerville, R.P.2    Shi, V.3    Rose, J.J.4    Halverson, D.C.5    Fowler, D.H.6
  • 63
    • 84979268324 scopus 로고    scopus 로고
    • Chimeric antigen receptors modified T-cells for cancer therapy
    • doi: 10.1093/jnci/djv439
    • Dai H, Wang Y, Lu X, Han W. Chimeric antigen receptors modified T-cells for cancer therapy. J Natl Cancer Inst. 2016;108: djv439. doi: 10.1093/jnci/djv439
    • (2016) J Natl Cancer Inst. , vol.108 , pp. djv439
    • Dai, H.1    Wang, Y.2    Lu, X.3    Han, W.4
  • 64
    • 85027527343 scopus 로고    scopus 로고
    • Murine donor 1928z CAR T cells exert potent graft-versus-lymphoma activity without graft-versus-host-disease
    • abstract 653
    • Smith M, James S, Davila ML, Velardi E, Argyropoulos EV, Gunset G, et al. Murine donor 1928z CAR T cells exert potent graft-versus-lymphoma activity without graft-versus-host-disease. Blood. 2016;128 (suppl): abstract 653.
    • (2016) Blood. , vol.128
    • Smith, M.1    James, S.2    Davila, M.L.3    Velardi, E.4    Argyropoulos, E.V.5    Gunset, G.6
  • 65
    • 84997241574 scopus 로고    scopus 로고
    • Co-infusion of haplo-identical CD19-chimeric antigen receptor T cells and stem cells achieved full donor engraftment in refractory acute lymphoblastic leukemia
    • Cai B, Guo M, Wang Y, Zhang Y, Yang J, Guo Y, et al. Co-infusion of haplo-identical CD19-chimeric antigen receptor T cells and stem cells achieved full donor engraftment in refractory acute lymphoblastic leukemia. J Hematol Oncol. 2016;9(1):131.
    • (2016) J Hematol Oncol. , vol.9 , Issue.1 , pp. 131
    • Cai, B.1    Guo, M.2    Wang, Y.3    Zhang, Y.4    Yang, J.5    Guo, Y.6
  • 66
    • 84904097189 scopus 로고    scopus 로고
    • Current concepts in the diagnosis and management of cytokine release syndrome
    • Lee DW, Gardner R, Porter DL, Louis CU, Ahmed N, Jensen M, et al. Current concepts in the diagnosis and management of cytokine release syndrome. Blood. 2014;124:188-95.
    • (2014) Blood. , vol.124 , pp. 188-195
    • Lee, D.W.1    Gardner, R.2    Porter, D.L.3    Louis, C.U.4    Ahmed, N.5    Jensen, M.6
  • 67
    • 84895066532 scopus 로고    scopus 로고
    • Toxicity management for patients receiving novel T-cell engaging therapies
    • 1:CAS:528:DC%2BC2cXnsVKmuw%3D%3D 24362408 4198063
    • Barrett DM, Teachey DT, Grupp SA. Toxicity management for patients receiving novel T-cell engaging therapies. Curr Opin Pediatr. 2014;26:43-9.
    • (2014) Curr Opin Pediatr , vol.26 , pp. 43-49
    • Barrett, D.M.1    Teachey, D.T.2    Grupp, S.A.3
  • 68
    • 84876325876 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
    • 1:CAS:528:DC%2BC3sXmsFKgtLo%3D 23527958 4058440
    • Grupp SA, Kalos M, Barrett D, Aplenc R, Porter DL, Rheingold SR, et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med. 2013;368:1509-18.
    • (2013) N Engl J Med , vol.368 , pp. 1509-1518
    • Grupp, S.A.1    Kalos, M.2    Barrett, D.3    Aplenc, R.4    Porter, D.L.5    Rheingold, S.R.6
  • 69
    • 85003952268 scopus 로고    scopus 로고
    • From CARs to TRUCKs and beyond: Safely en route to adoptive T-cell therapy for cancer
    • 1:STN:280:DC%2BC1c%2Fls1emsg%3D%3D
    • Dummy. From CARs to TRUCKs and beyond: safely en route to adoptive T-cell therapy for cancer. EBio Medicine. 2016;14:1-2.
    • (2016) EBio Medicine , vol.14 , pp. 1-2
    • Dummy1
  • 70
    • 84933510694 scopus 로고    scopus 로고
    • CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC2MXhtlSnsrfI 25999455 4481592
    • Maude SL, Teachey DT, Porter DL, Grupp SA. CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia. Blood. 2015;125:4017-23.
    • (2015) Blood , vol.125 , pp. 4017-4023
    • Maude, S.L.1    Teachey, D.T.2    Porter, D.L.3    Grupp, S.A.4
  • 71
    • 85027518580 scopus 로고    scopus 로고
    • CD19CAR T cell products of defined CD4:CD8 composition and transgene expression show prolonged persistence and durable MRD-negative remission in pediatric and young adult B-cell ALL
    • abstract 219
    • Gardner R, Smithers H, Leger KJ, Annesley CE, Summers C, Brown C, et al. CD19CAR T cell products of defined CD4:CD8 composition and transgene expression show prolonged persistence and durable MRD-negative remission in pediatric and young adult B-cell ALL. Blood. 2016;128(suppl): abstract 219.
    • (2016) Blood. , vol.128
    • Gardner, R.1    Smithers, H.2    Leger, K.J.3    Annesley, C.E.4    Summers, C.5    Brown, C.6
  • 72
    • 84974555520 scopus 로고    scopus 로고
    • CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
    • 27111235 4887159
    • Turtle CJ, Hanafi LA, Berger C, Gooley TA, Cherian S, Hudecek M, et al. CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients. J Clin Invest. 2016;126:2123-38.
    • (2016) J Clin Invest , vol.126 , pp. 2123-2138
    • Turtle, C.J.1    Hanafi, L.A.2    Berger, C.3    Gooley, T.A.4    Cherian, S.5    Hudecek, M.6
  • 73
    • 84975172606 scopus 로고    scopus 로고
    • Durable remissions in children with relapsed/refractory ALL treated with T cells engineered with a CD19-targeted chimeric antigen receptor (CTL019)
    • abstract 681
    • Grupp SA, Maude SL, Shaw PA, Aplenc R, Barrett DM, Callahan C, et al. Durable remissions in children with relapsed/refractory ALL treated with T cells engineered with a CD19-targeted chimeric antigen receptor (CTL019). Blood. 2015;126(suppl): abstract 681.
    • (2015) Blood. , vol.126
    • Grupp, S.A.1    Maude, S.L.2    Shaw, P.A.3    Aplenc, R.4    Barrett, D.M.5    Callahan, C.6
  • 74
    • 85027506970 scopus 로고    scopus 로고
    • Efficacy of humanized CD19-targeted chimeric antigen receptor (CAR)-modified T cells in children and young adults with relapsed/refractory acute lymphoblastic leukemia
    • abstract 217
    • Maude SL, Rheingold SR, Aplenc R, Teachey DT, Callahan C, Baniewicz D, et al. Efficacy of humanized CD19-targeted chimeric antigen receptor (CAR)-modified T cells in children and young adults with relapsed/refractory acute lymphoblastic leukemia. Blood. 2016;128 (suppl): abstract 217.
    • (2016) Blood. , vol.128
    • Maude, S.L.1    Rheingold, S.R.2    Aplenc, R.3    Teachey, D.T.4    Callahan, C.5    Baniewicz, D.6
  • 76
    • 85027531455 scopus 로고    scopus 로고
    • The effect of pembrolizumab in combination with CD19-targeted chimeric antigen receptor (CAR) T cells in relapsed acute lymphoblastic leukemia (ALL)
    • abstract 103
    • Maude SL, Hucks GE, Seif AE, Talekar MK, Teachey DT, Baniewicz D, et al. The effect of pembrolizumab in combination with CD19-targeted chimeric antigen receptor (CAR) T cells in relapsed acute lymphoblastic leukemia (ALL). J Clin Oncol. 2017;35(suppl): abstract 103.
    • (2017) J Clin Oncol. , vol.35
    • Maude, S.L.1    Hucks, G.E.2    Seif, A.E.3    Talekar, M.K.4    Teachey, D.T.5    Baniewicz, D.6
  • 78
    • 85027513422 scopus 로고    scopus 로고
    • Cars in leukemia: Relapse with antigen-negative leukemia originating from a single B cell expressing the leukemia-targeting CAR
    • abstract 281
    • Lacey SF, Xu J, Ruella M. Cars in leukemia: relapse with antigen-negative leukemia originating from a single B cell expressing the leukemia-targeting CAR. Blood 2016, 128 (suppl): abstract 281
    • (2016) Blood , vol.128
    • Lacey, S.F.1    Xu, J.2    Ruella, M.3
  • 79
    • 84886944148 scopus 로고    scopus 로고
    • Lessons learned from a highly-active CD22-specific chimeric antigen receptor
    • 23734316 3654586
    • Long AH, Haso WM, Orentas RJ. Lessons learned from a highly-active CD22-specific chimeric antigen receptor. Oncoimmunology. 2013;2:e23621.
    • (2013) Oncoimmunology , vol.2 , pp. e23621
    • Long, A.H.1    Haso, W.M.2    Orentas, R.J.3
  • 80
    • 84874027123 scopus 로고    scopus 로고
    • Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia
    • 1:CAS:528:DC%2BC3sXjt1WhsLw%3D 23243285 3575759
    • Haso W, Lee DW, Shah NN, Stetler-Stevenson M, Yuan CM, Pastan IH, et al. Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia. Blood. 2013;121:1165-74.
    • (2013) Blood , vol.121 , pp. 1165-1174
    • Haso, W.1    Lee, D.W.2    Shah, N.N.3    Stetler-Stevenson, M.4    Yuan, C.M.5    Pastan, I.H.6
  • 81
    • 85017333976 scopus 로고    scopus 로고
    • Minimal residual disease negative complete remissions following anti-CD22 chimeric antigen receptor (CAR) in children and young adults with relapsed/refractory acute lymphoblastic leukemia (ALL)
    • abstract 650
    • Shah nn, Yuan CM, Shalabi H, Yates B, Delbrook C, Zhang L, et al. Minimal residual disease negative complete remissions following anti-CD22 chimeric antigen receptor (CAR) in children and young adults with relapsed/refractory acute lymphoblastic leukemia (ALL). Blood. 2016;128(suppl): abstract 650.
    • (2016) Blood. , vol.128
    • Shah, N.N.1    Yuan, C.M.2    Shalabi, H.3    Yates, B.4    Delbrook, C.5    Zhang, L.6


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