-
2
-
-
12444270688
-
Epratuzumab, a humanized monoclonal antibody targeting CD22: characterization of in vitro properties
-
PID: 14506197
-
Carnahan J, Wang P, Kendall R, Chen C, Hu S, Boone T, Juan T, Talvenheimo J, Montestruque S, Sun J (2003) Epratuzumab, a humanized monoclonal antibody targeting CD22: characterization of in vitro properties. Clin Cancer Res 9:3982s–3990s
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3982s-3990s
-
-
Carnahan, J.1
Wang, P.2
Kendall, R.3
Chen, C.4
Hu, S.5
Boone, T.6
Juan, T.7
Talvenheimo, J.8
Montestruque, S.9
Sun, J.10
-
3
-
-
77950803212
-
B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy
-
Catalán D, Aravena O, Sabugo F, Wumann P, Soto L, Kalergis AM, Cuchacovich M, Aguillón JC (2010) B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy. Arth Res Ther 12:R68
-
(2010)
Arth Res Ther
, vol.12
, pp. R68
-
-
Catalán, D.1
Aravena, O.2
Sabugo, F.3
Wumann, P.4
Soto, L.5
Kalergis, A.M.6
Cuchacovich, M.7
Aguillón, J.C.8
-
4
-
-
0344936020
-
Inhibitory signals by B cell FcγRIIb
-
PID: 9638367
-
Coggeshall KM (1998) Inhibitory signals by B cell FcγRIIb. Curr Opin Immunol 10:306–312
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 306-312
-
-
Coggeshall, K.M.1
-
6
-
-
84945485927
-
The mechanistic impact of CD22 engagement with epratuzumab on B cell function: implications for the treatment of systemic lupus erythematosus
-
PID: 26212727
-
Dörner T, Shock A, Goldenberg DM, Lipsky PE (2015) The mechanistic impact of CD22 engagement with epratuzumab on B cell function: implications for the treatment of systemic lupus erythematosus. Autoimmun Rev 14:1079–1086
-
(2015)
Autoimmun Rev
, vol.14
, pp. 1079-1086
-
-
Dörner, T.1
Shock, A.2
Goldenberg, D.M.3
Lipsky, P.E.4
-
7
-
-
84937213929
-
Epratuzumab inhibits the production of proinflammatory but not regulatory cytokines by B cells from healthy donors and SLE-patients
-
Fleischer V, Sieber J, Fleischer SJ, Shock A, Heine G, Daridon C, Doerner T (2015a) Epratuzumab inhibits the production of proinflammatory but not regulatory cytokines by B cells from healthy donors and SLE-patients. Arth Res Ther 17:185
-
(2015)
Arth Res Ther
, vol.17
, pp. 185
-
-
Fleischer, V.1
Sieber, J.2
Fleischer, S.J.3
Shock, A.4
Heine, G.5
Daridon, C.6
Doerner, T.7
-
8
-
-
84964618012
-
Enhanced tyrosine phosphatase activity underlies dysregulated B-cell receptor signaling and promotes survival of human lupus B-cells
-
Fleischer SJ, Daridon C, Fleischer V, Lipsky PE, Dörner T (2015b) Enhanced tyrosine phosphatase activity underlies dysregulated B-cell receptor signaling and promotes survival of human lupus B-cells. Arthritis Rheumatol Accept Article. doi:10.1002/art.39559
-
(2015)
Arthritis Rheumatol Accept Article
-
-
Fleischer, S.J.1
Daridon, C.2
Fleischer, V.3
Lipsky, P.E.4
Dörner, T.5
-
9
-
-
33750699969
-
Epratuzumab in the therapy of oncological and immunological diseases
-
PID: 17069520
-
Goldenberg DM (2006) Epratuzumab in the therapy of oncological and immunological diseases. Expert Rev Anticancer Ther 6:1341–1353
-
(2006)
Expert Rev Anticancer Ther
, vol.6
, pp. 1341-1353
-
-
Goldenberg, D.M.1
-
10
-
-
13544259968
-
B cell selection and susceptibility to autoimmunity
-
PID: 15699102
-
Grimaldi CM, Hicks R, Diamond B (2005) B cell selection and susceptibility to autoimmunity. J Immunol 174:1775–1781
-
(2005)
J Immunol
, vol.174
, pp. 1775-1781
-
-
Grimaldi, C.M.1
Hicks, R.2
Diamond, B.3
-
11
-
-
10644277800
-
Two distinct tyrosine-based motifs enable the inhibitory receptor FcRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap
-
PID: 15456754
-
Isnardi I, Lesourne R, Bruhns P, Fridman WH, Cambier JC, Daëron M (2004) Two distinct tyrosine-based motifs enable the inhibitory receptor FcRIIB to cooperatively recruit the inositol phosphatases SHIP1/2 and the adapters Grb2/Grap. J Biol Chem 279:51931–51938
-
(2004)
J Biol Chem
, vol.279
, pp. 51931-51938
-
-
Isnardi, I.1
Lesourne, R.2
Bruhns, P.3
Fridman, W.H.4
Cambier, J.C.5
Daëron, M.6
-
12
-
-
41849121941
-
Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls
-
PID: 17673490
-
Jacobi AM, Goldenberg DM, Hiepe F, Radbruch A, Burmester GR, Dörner T (2008) Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls. Ann Rheum Dis 67:450–457
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 450-457
-
-
Jacobi, A.M.1
Goldenberg, D.M.2
Hiepe, F.3
Radbruch, A.4
Burmester, G.R.5
Dörner, T.6
-
13
-
-
70350431786
-
Grb2, a simple adapter with complex roles in lymphocyte development, function, and signaling
-
PID: 19909362
-
Jang IK, Zhang J, Gu H (2009) Grb2, a simple adapter with complex roles in lymphocyte development, function, and signaling. Immunol Rev 232:150–159
-
(2009)
Immunol Rev
, vol.232
, pp. 150-159
-
-
Jang, I.K.1
Zhang, J.2
Gu, H.3
-
14
-
-
11144348754
-
Antigen receptor signaling competence and the determination of B cell fate in B-lymphopoiesis
-
PID: 15578437
-
Keren Z, Melamed D (2005) Antigen receptor signaling competence and the determination of B cell fate in B-lymphopoiesis. Histol Histopathol 20:187–196
-
(2005)
Histol Histopathol
, vol.20
, pp. 187-196
-
-
Keren, Z.1
Melamed, D.2
-
15
-
-
33748467673
-
Selective dysregulation of the FcγRIIB receptor on memory B cells in SLE
-
PID: 16923849
-
Mackay M, Stanevsky A, Wang T, Aranow C, Li M, Koenig S, Ravetch JV, Diamond B (2006) Selective dysregulation of the FcγRIIB receptor on memory B cells in SLE. J Exp Med 203:2157–2164
-
(2006)
J Exp Med
, vol.203
, pp. 2157-2164
-
-
Mackay, M.1
Stanevsky, A.2
Wang, T.3
Aranow, C.4
Li, M.5
Koenig, S.6
Ravetch, J.V.7
Diamond, B.8
-
16
-
-
84945466055
-
Epratuzumab induces broad inhibition of B cell receptor proximal signaling but has opposing effects on distal signaling in B cell subsets: a profile of effects on functional immune signaling by single cell network profiling
-
Maloney A, Hotson D, Rapecki S, Fossati G, Lumb S, Rosen D, Putta S, Wale N, Spellmeyer D, Cesano A, Hawtin R, Shock A (2014) Epratuzumab induces broad inhibition of B cell receptor proximal signaling but has opposing effects on distal signaling in B cell subsets: a profile of effects on functional immune signaling by single cell network profiling. Arthritis Rheum 66:S1255
-
(2014)
Arthritis Rheum
, vol.66
, pp. S1255
-
-
Maloney, A.1
Hotson, D.2
Rapecki, S.3
Fossati, G.4
Lumb, S.5
Rosen, D.6
Putta, S.7
Wale, N.8
Spellmeyer, D.9
Cesano, A.10
Hawtin, R.11
Shock, A.12
-
17
-
-
0028347321
-
A 13-amino-acid motif in the cytoplasmic domain of Fc gamma RIIB modulates B-cell receptor signalling
-
PID: 8107887
-
Muta T, Kurosaki T, Misulovin Z, Sanchez M, Nussenzweig MC, Ravetch JV (1994) A 13-amino-acid motif in the cytoplasmic domain of Fc gamma RIIB modulates B-cell receptor signalling. Nature 368:70–73
-
(1994)
Nature
, vol.368
, pp. 70-73
-
-
Muta, T.1
Kurosaki, T.2
Misulovin, Z.3
Sanchez, M.4
Nussenzweig, M.C.5
Ravetch, J.V.6
-
18
-
-
79951853901
-
Fc gamma receptor IIb modulates the molecular Grb2 interaction network in activated B cells
-
PID: 21262349
-
Neumann K, Oellerich T, Heine I, Urlaub H, Engelke M (2011) Fc gamma receptor IIb modulates the molecular Grb2 interaction network in activated B cells. Cell Signal 23:893–900
-
(2011)
Cell Signal
, vol.23
, pp. 893-900
-
-
Neumann, K.1
Oellerich, T.2
Heine, I.3
Urlaub, H.4
Engelke, M.5
-
19
-
-
18844424394
-
The role of CD22 and other inhibitory co-receptors in B-cell activation
-
PID: 15886119
-
Nitschke L (2005) The role of CD22 and other inhibitory co-receptors in B-cell activation. Curr Opin Immunol 17:290–297
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 290-297
-
-
Nitschke, L.1
-
20
-
-
0035941215
-
CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1
-
PID: 11551923
-
Otipoby KL, Draves KE, Clark EA (2001) CD22 regulates B cell receptor-mediated signals via two domains that independently recruit Grb2 and SHP-1. J Biol Chem 276:44315–44322
-
(2001)
J Biol Chem
, vol.276
, pp. 44315-44322
-
-
Otipoby, K.L.1
Draves, K.E.2
Clark, E.A.3
-
21
-
-
0034625416
-
CD22 Forms a quaternary complex with SHIP, Grb2, and Shc: a pathway for regulation of B lymphocyte antigen receptor-induced calcium flux
-
PID: 10748054
-
Poe JC, Fujimoto M, Jansen PJ, Miller AS, Tedder TF (2000) CD22 Forms a quaternary complex with SHIP, Grb2, and Shc: a pathway for regulation of B lymphocyte antigen receptor-induced calcium flux. J Biol Chem 275:17420–17427
-
(2000)
J Biol Chem
, vol.275
, pp. 17420-17427
-
-
Poe, J.C.1
Fujimoto, M.2
Jansen, P.J.3
Miller, A.S.4
Tedder, T.F.5
-
22
-
-
41349118741
-
Bispecific anti-CD20/22 antibodies inhibit B-cell lymphoma proliferation by a unique mechanism of action
-
PID: 18025153
-
Qu Z, Goldenberg DM, Cardillo TM, Shi V, Hansen HJ, Chang C-H (2008) Bispecific anti-CD20/22 antibodies inhibit B-cell lymphoma proliferation by a unique mechanism of action. Blood 111:2211–2219
-
(2008)
Blood
, vol.111
, pp. 2211-2219
-
-
Qu, Z.1
Goldenberg, D.M.2
Cardillo, T.M.3
Shi, V.4
Hansen, H.J.5
Chang, C.-H.6
-
24
-
-
84885332343
-
Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab
-
PID: 23821660
-
Rossi EA, Goldenberg DM, Michel R, Rossi DL, Wallace DJ, Chang C-H (2013) Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab. Blood 122:3020–3029
-
(2013)
Blood
, vol.122
, pp. 3020-3029
-
-
Rossi, E.A.1
Goldenberg, D.M.2
Michel, R.3
Rossi, D.L.4
Wallace, D.J.5
Chang, C.-H.6
-
25
-
-
0017124844
-
Single step separation of human T and B cells using AET treated SRBC rosettes
-
PID: 1085784
-
Saxon A, Feldhaus J, Robins RA (1976) Single step separation of human T and B cells using AET treated SRBC rosettes. J Immunol Methods 12:285–288
-
(1976)
J Immunol Methods
, vol.12
, pp. 285-288
-
-
Saxon, A.1
Feldhaus, J.2
Robins, R.A.3
-
26
-
-
84971238155
-
Pharmacodynamic effects of the CD22-targeted monoclonal antibody epratuzumab on B cells in patients with systemic lupus erythematosus
-
Shock A, Kilgallen B, Koetse W, Stach C, Bongardt S, Galateanu C (2014) Pharmacodynamic effects of the CD22-targeted monoclonal antibody epratuzumab on B cells in patients with systemic lupus erythematosus. Arthritis Rheum 66:S856
-
(2014)
Arthritis Rheum
, vol.66
, pp. S856
-
-
Shock, A.1
Kilgallen, B.2
Koetse, W.3
Stach, C.4
Bongardt, S.5
Galateanu, C.6
-
27
-
-
84874429605
-
CD22 ligation inhibits downstream B cell receptor signaling and Ca2+ flux upon activation
-
PID: 23233360
-
Sieger N, Fleischer S, Mei H, Reiter K, Shock A, Burmester G, Daridon C, Dörner T (2013) CD22 ligation inhibits downstream B cell receptor signaling and Ca2+ flux upon activation. Arthritis Rheum 65:770–779
-
(2013)
Arthritis Rheum
, vol.65
, pp. 770-779
-
-
Sieger, N.1
Fleischer, S.2
Mei, H.3
Reiter, K.4
Shock, A.5
Burmester, G.6
Daridon, C.7
Dörner, T.8
-
28
-
-
84861161715
-
Role of inhibitory BCR co-receptors in immunity
-
PID: 22394175
-
Tsubata T (2012) Role of inhibitory BCR co-receptors in immunity. Infect Disord Drug Targets 12:181–190
-
(2012)
Infect Disord Drug Targets
, vol.12
, pp. 181-190
-
-
Tsubata, T.1
-
29
-
-
77954232707
-
Therapeutic control of B cell activation via recruitment of Fcγ receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold
-
PID: 20506263
-
Veri M-C, Burke S, Huang L, Li H, Gorlatov S, Tuaillon N, Rainey GJ, Ciccarone V, Zhang T, Shah K, Jin L, Ning L, Minor T, Moore PA, Koenig S, Hohnson S, Bonvini E (2010) Therapeutic control of B cell activation via recruitment of Fcγ receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold. Arthritis Rheum 62:1933–1943
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1933-1943
-
-
Veri, M.-C.1
Burke, S.2
Huang, L.3
Li, H.4
Gorlatov, S.5
Tuaillon, N.6
Rainey, G.J.7
Ciccarone, V.8
Zhang, T.9
Shah, K.10
Jin, L.11
Ning, L.12
Minor, T.13
Moore, P.A.14
Koenig, S.15
Hohnson, S.16
Bonvini, E.17
|