메뉴 건너뛰기




Volumn 107, Issue , 2017, Pages 48-58

Host blood RNA signatures predict the outcome of tuberculosis treatment

(22)  Thompson, Ethan G d   Du, Ying d   Malherbe, Stephanus T a,b   Shankar, Smitha d   Braun, Jackie d   Valvo, Joe d   Ronacher, Katharina a,b,e   Tromp, Gerard a,b   Tabb, David L a,b   Alland, David f   Shenai, Shubhada f   Via, Laura E g,h   Warwick, James b,i   Aderem, Alan d   Scriba, Thomas J j   Winter, Jill k   Walzl, Gerhard a,b   Zak, Daniel E d   Du Plessis, Nelita a,b   Loxton, Andre G a,b   more..


Author keywords

Biomarkers; Host response; Mitochondria; Transcriptome; Tuberculosis treatment

Indexed keywords

BIOLOGICAL MARKER; RNA; TRANSCRIPTOME; TUBERCULOSTATIC AGENT;

EID: 85027493960     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2017.08.004     Document Type: Article
Times cited : (130)

References (33)
  • 1
    • 84987660805 scopus 로고    scopus 로고
    • Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure
    • Malherbe, S.T., Shenai, S., Ronacher, K., Loxton, A.G., Dolganov, G., Kriel, M., et al. Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure. Nat Med 22:10 (2016), 1094–1100.
    • (2016) Nat Med , vol.22 , Issue.10 , pp. 1094-1100
    • Malherbe, S.T.1    Shenai, S.2    Ronacher, K.3    Loxton, A.G.4    Dolganov, G.5    Kriel, M.6
  • 2
    • 84959505947 scopus 로고    scopus 로고
    • Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis
    • Sweeney, T.E., Braviak, L., Tato, C.M., Khatri, P., Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis. Lancet Respir Med 4:3 (2016), 213–224.
    • (2016) Lancet Respir Med , vol.4 , Issue.3 , pp. 213-224
    • Sweeney, T.E.1    Braviak, L.2    Tato, C.M.3    Khatri, P.4
  • 3
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry, M.P., Graham, C.M., McNab, F.W., Xu, Z., Bloch, S.A., Oni, T., et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466:7309 (2010), 973–977.
    • (2010) Nature , vol.466 , Issue.7309 , pp. 973-977
    • Berry, M.P.1    Graham, C.M.2    McNab, F.W.3    Xu, Z.4    Bloch, S.A.5    Oni, T.6
  • 4
    • 84886613855 scopus 로고    scopus 로고
    • Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study
    • Kaforou, M., Wright, V.J., Oni, T., French, N., Anderson, S.T., Bangani, N., et al. Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study. PLoS Med, 10(10), 2013, e1001538.
    • (2013) PLoS Med , vol.10 , Issue.10 , pp. e1001538
    • Kaforou, M.1    Wright, V.J.2    Oni, T.3    French, N.4    Anderson, S.T.5    Bangani, N.6
  • 6
    • 84957943318 scopus 로고    scopus 로고
    • Concise gene signature for point-of-care classification of tuberculosis
    • Maertzdorf, J., McEwen, G., Weiner, J. 3rd, Tian, S., Lader, E., Schriek, U., et al. Concise gene signature for point-of-care classification of tuberculosis. EMBO Mol Med 8:2 (2016), 86–95.
    • (2016) EMBO Mol Med , vol.8 , Issue.2 , pp. 86-95
    • Maertzdorf, J.1    McEwen, G.2    Weiner, J.3    Tian, S.4    Lader, E.5    Schriek, U.6
  • 7
    • 84975914135 scopus 로고    scopus 로고
    • A blood RNA signature for tuberculosis disease risk: a prospective cohort study
    • Zak, D.E., Penn-Nicholson, A., Scriba, T.J., Thompson, E., Suliman, S., Amon, L.M., et al. A blood RNA signature for tuberculosis disease risk: a prospective cohort study. Lancet 387:10035 (2016), 2312–2322.
    • (2016) Lancet , vol.387 , Issue.10035 , pp. 2312-2322
    • Zak, D.E.1    Penn-Nicholson, A.2    Scriba, T.J.3    Thompson, E.4    Suliman, S.5    Amon, L.M.6
  • 8
    • 84867031010 scopus 로고    scopus 로고
    • Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy
    • Bloom, C.I., Graham, C.M., Berry, M.P., Wilkinson, K.A., Oni, T., Rozakeas, F., et al. Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy. PLoS One, 7(10), 2012, e46191.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e46191
    • Bloom, C.I.1    Graham, C.M.2    Berry, M.P.3    Wilkinson, K.A.4    Oni, T.5    Rozakeas, F.6
  • 9
    • 84872978097 scopus 로고    scopus 로고
    • Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response
    • Cliff, J.M., Lee, J.S., Constantinou, N., Cho, J.E., Clark, T.G., Ronacher, K., et al. Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response. J Infect Dis 207:1 (2013), 18–29.
    • (2013) J Infect Dis , vol.207 , Issue.1 , pp. 18-29
    • Cliff, J.M.1    Lee, J.S.2    Constantinou, N.3    Cho, J.E.4    Clark, T.G.5    Ronacher, K.6
  • 10
    • 84983470396 scopus 로고    scopus 로고
    • Bacterial loads measured by the Xpert MTB/RIF assay as markers of culture conversion and bacteriological cure in pulmonary TB
    • Shenai, S., Ronacher, K., Malherbe, S., Stanley, K., Kriel, M., Winter, J., et al. Bacterial loads measured by the Xpert MTB/RIF assay as markers of culture conversion and bacteriological cure in pulmonary TB. PLoS One, 11(8), 2016, e0160062.
    • (2016) PLoS One , vol.11 , Issue.8 , pp. e0160062
    • Shenai, S.1    Ronacher, K.2    Malherbe, S.3    Stanley, K.4    Kriel, M.5    Winter, J.6
  • 11
  • 12
    • 84928987900 scopus 로고    scopus 로고
    • HTSeq–a Python framework to work with high-throughput sequencing data
    • Anders, S., Pyl, P.T., Huber, W., HTSeq–a Python framework to work with high-throughput sequencing data. Bioinformatics 31:2 (2015), 166–169.
    • (2015) Bioinformatics , vol.31 , Issue.2 , pp. 166-169
    • Anders, S.1    Pyl, P.T.2    Huber, W.3
  • 13
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson, M.D., McCarthy, D.J., Smyth, G.K., edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26:1 (2010), 139–140.
    • (2010) Bioinformatics , vol.26 , Issue.1 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 14
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini, Y., Hochberg, Y., Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser Bioinforma 57 (1995), 289–300.
    • (1995) J R Stat Soc Ser Bioinforma , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 15
    • 84962031735 scopus 로고    scopus 로고
    • A language and environment for statistical computing
    • R Foundation for Statistical Compuing Vienna, Austria
    • Team, R.C., A language and environment for statistical computing. 2015, R Foundation for Statistical Compuing, Vienna, Austria.
    • (2015)
    • Team, R.C.1
  • 16
    • 84889826520 scopus 로고    scopus 로고
    • Exploring alternative biomaterials for diagnosis of pulmonary tuberculosis in HIV-negative patients by use of the GeneXpert MTB/RIF assay
    • Shenai, S., Amisano, D., Ronacher, K., Kriel, M., Banada, P.P., Song, T., et al. Exploring alternative biomaterials for diagnosis of pulmonary tuberculosis in HIV-negative patients by use of the GeneXpert MTB/RIF assay. J Clin Microbiol 51:12 (2013), 4161–4166.
    • (2013) J Clin Microbiol , vol.51 , Issue.12 , pp. 4161-4166
    • Shenai, S.1    Amisano, D.2    Ronacher, K.3    Kriel, M.4    Banada, P.P.5    Song, T.6
  • 19
    • 84896345445 scopus 로고    scopus 로고
    • Molecular signatures of antibody responses derived from a systems biology study of five human vaccines
    • Li, S., Rouphael, N., Duraisingham, S., Romero-Steiner, S., Presnell, S., Davis, C., et al. Molecular signatures of antibody responses derived from a systems biology study of five human vaccines. Nat Immunol 15:2 (2014), 195–204.
    • (2014) Nat Immunol , vol.15 , Issue.2 , pp. 195-204
    • Li, S.1    Rouphael, N.2    Duraisingham, S.3    Romero-Steiner, S.4    Presnell, S.5    Davis, C.6
  • 20
    • 84876745847 scopus 로고    scopus 로고
    • Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines
    • Obermoser, G., Presnell, S., Domico, K., Xu, H., Wang, Y., Anguiano, E., et al. Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines. Immunity 38:4 (2013), 831–844.
    • (2013) Immunity , vol.38 , Issue.4 , pp. 831-844
    • Obermoser, G.1    Presnell, S.2    Domico, K.3    Xu, H.4    Wang, Y.5    Anguiano, E.6
  • 21
    • 84881369293 scopus 로고    scopus 로고
    • Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment
    • Friedrich, S.O., Rachow, A., Saathoff, E., Singh, K., Mangu, C.D., Dawson, R., et al. Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment. Lancet Respir Med 1:6 (2013), 462–470.
    • (2013) Lancet Respir Med , vol.1 , Issue.6 , pp. 462-470
    • Friedrich, S.O.1    Rachow, A.2    Saathoff, E.3    Singh, K.4    Mangu, C.D.5    Dawson, R.6
  • 22
    • 0036838699 scopus 로고    scopus 로고
    • Critical role of mitochondrial damage in determining outcome of macrophage infection with Mycobacterium tuberculosis
    • Duan, L., Gan, H., Golan, D.E., Remold, H.G., Critical role of mitochondrial damage in determining outcome of macrophage infection with Mycobacterium tuberculosis. J Immunol 169:9 (2002), 5181–5187.
    • (2002) J Immunol , vol.169 , Issue.9 , pp. 5181-5187
    • Duan, L.1    Gan, H.2    Golan, D.E.3    Remold, H.G.4
  • 24
    • 33644837680 scopus 로고    scopus 로고
    • A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis
    • Chen, M., Gan, H., Remold, H.G., A mechanism of virulence: virulent Mycobacterium tuberculosis strain H37Rv, but not attenuated H37Ra, causes significant mitochondrial inner membrane disruption in macrophages leading to necrosis. J Immunol 176:6 (2006), 3707–3716.
    • (2006) J Immunol , vol.176 , Issue.6 , pp. 3707-3716
    • Chen, M.1    Gan, H.2    Remold, H.G.3
  • 26
    • 85008645140 scopus 로고    scopus 로고
    • Unbiased identification of blood-based biomarkers for pulmonary tuberculosis by modeling and mining molecular interaction networks
    • Sambarey, A., Devaprasad, A., Mohan, A., Ahmed, A., Nayak, S., Swaminathan, S., et al. Unbiased identification of blood-based biomarkers for pulmonary tuberculosis by modeling and mining molecular interaction networks. EBioMedicine 15 (2017), 112–126.
    • (2017) EBioMedicine , vol.15 , pp. 112-126
    • Sambarey, A.1    Devaprasad, A.2    Mohan, A.3    Ahmed, A.4    Nayak, S.5    Swaminathan, S.6
  • 27
    • 84961290384 scopus 로고    scopus 로고
    • UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis
    • Moon, J.S., Lee, S., Park, M.A., Siempos, I.I., Haslip, M., Lee, P.J., et al. UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis. J Clin Investig 125:2 (2015), 665–680.
    • (2015) J Clin Investig , vol.125 , Issue.2 , pp. 665-680
    • Moon, J.S.1    Lee, S.2    Park, M.A.3    Siempos, I.I.4    Haslip, M.5    Lee, P.J.6
  • 28
    • 84894277461 scopus 로고    scopus 로고
    • Human gene variants linked to enhanced NLRP3 activity limit intramacrophage growth of Mycobacterium tuberculosis
    • Eklund, D., Welin, A., Andersson, H., Verma, D., Soderkvist, P., Stendahl, O., et al. Human gene variants linked to enhanced NLRP3 activity limit intramacrophage growth of Mycobacterium tuberculosis. J Infect Dis 209:5 (2014), 749–753.
    • (2014) J Infect Dis , vol.209 , Issue.5 , pp. 749-753
    • Eklund, D.1    Welin, A.2    Andersson, H.3    Verma, D.4    Soderkvist, P.5    Stendahl, O.6
  • 29
    • 84856033488 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis
    • Dorhoi, A., Nouailles, G., Jorg, S., Hagens, K., Heinemann, E., Pradl, L., et al. Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis. Eur J Immunol 42:2 (2012), 374–384.
    • (2012) Eur J Immunol , vol.42 , Issue.2 , pp. 374-384
    • Dorhoi, A.1    Nouailles, G.2    Jorg, S.3    Hagens, K.4    Heinemann, E.5    Pradl, L.6
  • 30
    • 77951157392 scopus 로고    scopus 로고
    • Pattern recognition receptors require N-glycosylation to mediate plant immunity
    • Haweker, H., Rips, S., Koiwa, H, Salomon, S., Saijo, Y., Chinchilla, D., et al. Pattern recognition receptors require N-glycosylation to mediate plant immunity. J Biol Chem 285:7 (2010), 4629–4636.
    • (2010) J Biol Chem , vol.285 , Issue.7 , pp. 4629-4636
    • Haweker, H.1    Rips, S.2    Koiwa, H.3    Salomon, S.4    Saijo, Y.5    Chinchilla, D.6
  • 31
    • 85000919274 scopus 로고    scopus 로고
    • Intracellular innate immune surveillance devices in plants and animals
    • Jones, J.D., Vance, R.E., Dangl, J.L., Intracellular innate immune surveillance devices in plants and animals. Science, 354(6316), 2016.
    • (2016) Science , vol.354 , Issue.6316
    • Jones, J.D.1    Vance, R.E.2    Dangl, J.L.3
  • 32
    • 84881478367 scopus 로고    scopus 로고
    • A long noncoding RNA mediates both activation and repression of immune response genes
    • Carpenter, S., Aiello, D., Atianand, M.K., Ricci, E.P., Gandhi, P., Hall, L.L., et al. A long noncoding RNA mediates both activation and repression of immune response genes. Science 341:6147 (2013), 789–792.
    • (2013) Science , vol.341 , Issue.6147 , pp. 789-792
    • Carpenter, S.1    Aiello, D.2    Atianand, M.K.3    Ricci, E.P.4    Gandhi, P.5    Hall, L.L.6
  • 33
    • 84897959389 scopus 로고    scopus 로고
    • Progress in tuberculosis vaccine development and host-directed therapies–a state of the art review
    • Kaufmann, S.H., Lange, C., Rao, M., Balaji, K.N., Lotze, M., Schito, M., et al. Progress in tuberculosis vaccine development and host-directed therapies–a state of the art review. Lancet Respir Med 2:4 (2014), 301–320.
    • (2014) Lancet Respir Med , vol.2 , Issue.4 , pp. 301-320
    • Kaufmann, S.H.1    Lange, C.2    Rao, M.3    Balaji, K.N.4    Lotze, M.5    Schito, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.