-
1
-
-
79952467900
-
Thiamin (vitamin B1) biosynthesis and regulation: A rich source of antimicrobial drug targets?
-
Du, Q., Wang, H. and Xie, J. (2011) Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets? Int. J. Biol. Sci. 7, 41–52 doi:10.7150/ijbs.7.41
-
(2011)
Int. J. Biol. Sci.
, vol.7
, pp. 41-52
-
-
Du, Q.1
Wang, H.2
Xie, J.3
-
2
-
-
67650729745
-
The structural and biochemical foundations of thiamin biosynthesis
-
Jurgenson, C.T., Begley, T.P. and Ealick, S.E. (2009) The structural and biochemical foundations of thiamin biosynthesis. Annu. Rev. Biochem. 78, 569–603 doi:10.1146/annurev.biochem.78.072407.102340
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 569-603
-
-
Jurgenson, C.T.1
Begley, T.P.2
Ealick, S.E.3
-
3
-
-
0032992583
-
Cloning and characterization of the thiD/J gene of Escherichia coli encoding a thiamin-synthesizing bifunctional enzyme, hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
-
Mizote, T., Tsuda, M., Smith, D.D.S., Nakayama, H. and Nakazawa, T. (1999) Cloning and characterization of the thiD/J gene of Escherichia coli encoding a thiamin-synthesizing bifunctional enzyme, hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase. Microbiology 145, 495–501 doi:10.1099/13500872-145-2-495
-
(1999)
Microbiology
, vol.145
, pp. 495-501
-
-
Mizote, T.1
Tsuda, M.2
Smith, D.D.S.3
Nakayama, H.4
Nakazawa, T.5
-
4
-
-
0032564596
-
Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase
-
Reddick, J.J., Kinsland, C., Nicewonger, R., Christian, T., Downs, D.M., Winkler, M.E. et al. (1998) Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase. Tetrahedron 54, 15983–15991 doi:10.1016/S0040-4020(98)01006-0
-
(1998)
Tetrahedron
, vol.54
, pp. 15983-15991
-
-
Reddick, J.J.1
Kinsland, C.2
Nicewonger, R.3
Christian, T.4
Downs, D.M.5
Winkler, M.E.6
-
5
-
-
1342283001
-
Characterization of two kinases involved in thiamine pyrophosphate and pyridoxal phosphate biosynthesis in Bacillus subtilis: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and pyridoxal kinase
-
Park, J.-H., Burns, K., Kinsland, C. and Begley, T.P. (2004) Characterization of two kinases involved in thiamine pyrophosphate and pyridoxal phosphate biosynthesis in Bacillus subtilis: 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and pyridoxal kinase. J. Bacteriol. 186, 1571–1573 doi:10.1128/ JB.186.5.1571-1573.2004
-
(2004)
J. Bacteriol.
, vol.186
, pp. 1571-1573
-
-
Park, J.-H.1
Burns, K.2
Kinsland, C.3
Begley, T.P.4
-
6
-
-
0024978257
-
Purification and properties of hydroxymethylpyrimidine kinase from Escherichia coli
-
Mizote, T. and Nakayama, H. (1989) Purification and properties of hydroxymethylpyrimidine kinase from Escherichia coli. Biochim. Biophys. Acta, Gen. Subj. 991, 109–113 doi:10.1016/0304-4165(89)90035-4
-
(1989)
Biochim. Biophys. Acta, Gen. Subj.
, vol.991
, pp. 109-113
-
-
Mizote, T.1
Nakayama, H.2
-
7
-
-
0033623202
-
Action of the thiamine antagonist bacimethrin on thiamine biosynthesis
-
Zilles, J.L., Croal, L.R. and Downs, D.M. (2000) Action of the thiamine antagonist bacimethrin on thiamine biosynthesis. J. Bacteriol. 182, 5606–5610 doi:10.1128/JB.182.19.5606-5610.2000
-
(2000)
J. Bacteriol.
, vol.182
, pp. 5606-5610
-
-
Zilles, J.L.1
Croal, L.R.2
Downs, D.M.3
-
8
-
-
0036178687
-
Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 Å resolution
-
Cheng, G., Bennett, E.M., Begley, T.P. and Ealick, S.E. (2002) Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 Å resolution. Structure 10, 225–235 doi:10.1016/S0969-2126(02)00708-6
-
(2002)
Structure
, vol.10
, pp. 225-235
-
-
Cheng, G.1
Bennett, E.M.2
Begley, T.P.3
Ealick, S.E.4
-
9
-
-
84932194594
-
Dynamics in microbial communities: Unraveling mechanisms to identify principles
-
Konopka, A., Stephen Lindemann, S. and Fredrickson, J. (2015) Dynamics in microbial communities: unraveling mechanisms to identify principles. ISME J. 9, 1488–1495 doi:10.1038/ismej.2014.251
-
(2015)
ISME J.
, vol.9
, pp. 1488-1495
-
-
Konopka, A.1
Stephen Lindemann, S.2
Fredrickson, J.3
-
10
-
-
0001153455
-
Bacimethrin, a new antibiotic produced by Bacillus megaterium
-
Tanaka, F., Takeuchi, S., Tanaka, N., Yonehara, H., Umezawa, H. and Sumiki, Y. (1961) Bacimethrin, a new antibiotic produced by Bacillus megaterium. J. Antibiot. Ser. A 14, 161–162
-
(1961)
J. Antibiot. Ser. A
, vol.14
, pp. 161-162
-
-
Tanaka, F.1
Takeuchi, S.2
Tanaka, N.3
Yonehara, H.4
Umezawa, H.5
Sumiki, Y.6
-
11
-
-
0023619263
-
Metabolic products of microorganisms. 239. Bacimethrin isolated from Streptomyces albus. Identification, derivatives, synthesis and biological properties
-
Drautz, H., Messerer, W., Zähner, H., Breiding-Mack, S. and Zeeck, A. (1987) Metabolic products of microorganisms. 239. Bacimethrin isolated from Streptomyces albus. Identification, derivatives, synthesis and biological properties. J. Antibiot. 40, 1431–1439 doi:10.7164/antibiotics.40.1431
-
(1987)
J. Antibiot.
, vol.40
, pp. 1431-1439
-
-
Drautz, H.1
Messerer, W.2
Zähner, H.3
Breiding-Mack, S.4
Zeeck, A.5
-
12
-
-
84898888859
-
Biosynthesis of a thiamin antivitamin in Clostridium botulinum
-
Cooper, L.E., O’Leary, S.E. and Begley, T.P. (2014) Biosynthesis of a thiamin antivitamin in Clostridium botulinum. Biochemistry 53, 2215–2217 doi:10.1021/bi500281a
-
(2014)
Biochemistry
, vol.53
, pp. 2215-2217
-
-
Cooper, L.E.1
O’Leary, S.E.2
Begley, T.P.3
-
13
-
-
0035801805
-
The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite
-
Reddick, J.J., Saha, S., Lee, J.-m., Melnick, J.S., Perkins, J. and Begley, T.P. (2001) The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite. Bioorg. Med. Chem. Lett. 11, 2245–2248 doi:10.1016/S0960-894X(01)00373-0
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 2245-2248
-
-
Reddick, J.J.1
Saha, S.2
Lee, J.-M.3
Melnick, J.S.4
Perkins, J.5
Begley, T.P.6
-
14
-
-
0000453831
-
Some analogs of toxopyrimidine and methioprim
-
Okuda, T. and Price, C.C. (1958) Some analogs of toxopyrimidine and methioprim. J. Org. Chem. 23, 1738–1741 doi:10.1021/jo01105a043
-
(1958)
J. Org. Chem.
, vol.23
, pp. 1738-1741
-
-
Okuda, T.1
Price, C.C.2
-
15
-
-
49749189574
-
The antithiamine activity of the 2-alkylthio analogs of thiamine in microorganisms
-
Sakuragi, T. (1958) The antithiamine activity of the 2-alkylthio analogs of thiamine in microorganisms. Arch. Biochem. Biophys. 74, 362–371 doi:10.1016/0003-9861(58)90007-9
-
(1958)
Arch. Biochem. Biophys.
, vol.74
, pp. 362-371
-
-
Sakuragi, T.1
-
16
-
-
80053946165
-
A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: Comparative genomic and experimental evidence for a cryptic role in thiamin metabolism
-
Pribat, A., Blaby, I.K., Lara-Núñez, A., Jeanguenin, L., Fouquet, R., Frelin, O. et al. (2011) A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism. Funct. Integr. Genomics 11, 467–478 doi:10.1007/s10142-011-0224-5
-
(2011)
Funct. Integr. Genomics
, vol.11
, pp. 467-478
-
-
Pribat, A.1
Blaby, I.K.2
Lara-Núñez, A.3
Jeanguenin, L.4
Fouquet, R.5
Frelin, O.6
-
17
-
-
0021241330
-
Reversal of pyrithiamine-induced growth inhibition of Saccharomyces cerevisiae by oxythiamine
-
Iwashima, A., Yoshioka, K., Nishimura, H. and Nosaka, K. (1984) Reversal of pyrithiamine-induced growth inhibition of Saccharomyces cerevisiae by oxythiamine. Experientia 40, 582–583 doi:10.1007/BF01982343
-
(1984)
Experientia
, vol.40
, pp. 582-583
-
-
Iwashima, A.1
Yoshioka, K.2
Nishimura, H.3
Nosaka, K.4
-
18
-
-
32544451943
-
Modification of thiamine pyrophosphate dependent enzyme activity by oxythiamine in Saccharomyces cerevisiae cells
-
Tylicki, A., Czerniecki, J., Dobrzyn, P., Matanowska, A., Olechno, A. and Strumilo, S. (2005) Modification of thiamine pyrophosphate dependent enzyme activity by oxythiamine in Saccharomyces cerevisiae cells. Can. J. Microbiol. 51, 833–839 doi:10.1139/w05-072
-
(2005)
Can. J. Microbiol.
, vol.51
, pp. 833-839
-
-
Tylicki, A.1
Czerniecki, J.2
Dobrzyn, P.3
Matanowska, A.4
Olechno, A.5
Strumilo, S.6
-
19
-
-
84883313454
-
A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism
-
Goyer, A., Hasnain, G., Frelin, O., Ralat, M.A., Gregory, III, J.F. and Hanson, A.D. (2013) A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism. Biochem. J. 454, 533–542 doi:10.1042/BJ20130516
-
(2013)
Biochem. J.
, vol.454
, pp. 533-542
-
-
Goyer, A.1
Hasnain, G.2
Frelin, O.3
Ralat, M.A.4
Gregory, J.F.5
Hanson, A.D.6
-
20
-
-
6344235639
-
A genetic screen for the identification of thiamin metabolic genes
-
Lawhorn, B.G., Gerdes, S.Y. and Begley, T.P. (2004) A genetic screen for the identification of thiamin metabolic genes. J. Biol. Chem. 279, 43555–43559 doi:10.1074/jbc.M404284200
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43555-43559
-
-
Lawhorn, B.G.1
Gerdes, S.Y.2
Begley, T.P.3
-
21
-
-
84872715396
-
Metabolite damage and its repair or pre-emption
-
Linster, C.L., Van Schaftingen, E. and Hanson, A.D. (2013) Metabolite damage and its repair or pre-emption. Nat. Chem. Biol. 9, 72–80 doi:10.1038/ nchembio.1141
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 72-80
-
-
Linster, C.L.1
Van Schaftingen, E.2
Hanson, A.D.3
-
22
-
-
84877770147
-
Metabolite proofreading, a neglected aspect of intermediary metabolism
-
Van Schaftingen, E., Rzem, R., Marbaix, A., Collard, F., Veiga-da-Cunha, M. and Linster, C.L. (2013) Metabolite proofreading, a neglected aspect of intermediary metabolism. J. Inherit. Metab. Dis. 36, 427–434 doi:10.1007/s10545-012-9571-1
-
(2013)
J. Inherit. Metab. Dis.
, vol.36
, pp. 427-434
-
-
Van Schaftingen, E.1
Rzem, R.2
Marbaix, A.3
Collard, F.4
Veiga-Da-Cunha, M.5
Linster, C.L.6
-
23
-
-
25644458211
-
The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes
-
Overbeek, R., Begley, T., Butler, R.M., Choudhuri, J.V., Chuang, H.-Y., Cohoon, M. et al. (2005) The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes. Nucleic Acids Res. 33, 5691–5702 doi:10.1093/nar/gki866
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5691-5702
-
-
Overbeek, R.1
Begley, T.2
Butler, R.M.3
Choudhuri, J.V.4
Chuang, H.-Y.5
Cohoon, M.6
-
24
-
-
36448991500
-
Clustal W and Clustal X version 2.0
-
Larkin, M.A., Blackshields, G., Brown, N.P., Chenna, R., McGettigan, P.A., McWilliam, H. et al. (2007) Clustal W and Clustal X version 2.0. Bioinformatics 23, 2947–2948 doi:10.1093/bioinformatics/btm404
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
Blackshields, G.2
Brown, N.P.3
Chenna, R.4
McGettigan, P.A.5
McWilliam, H.6
-
25
-
-
79957613599
-
MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
-
Tamura, K., Peterson, D., Peterson, N., Stecher, G., Nei, M. and Kumar, S. (2011) MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28, 2731–2739 doi:10.1093/molbev/msr121
-
(2011)
Mol. Biol. Evol.
, vol.28
, pp. 2731-2739
-
-
Tamura, K.1
Peterson, D.2
Peterson, N.3
Stecher, G.4
Nei, M.5
Kumar, S.6
-
26
-
-
31544450286
-
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
-
2006.0008
-
Baba, T., Ara, T., Hasegawa, M., Takai, Y., Okumura, Y., Baba, M. et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006.0008 doi:10.1038/msb4100050
-
(2006)
Mol. Syst. Biol.
, vol.2
-
-
Baba, T.1
Ara, T.2
Hasegawa, M.3
Takai, Y.4
Okumura, Y.5
Baba, M.6
-
27
-
-
0034612342
-
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
-
Datsenko, K.A. and Wanner, B.L. (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl Acad. Sci. U.S.A. 97, 6640–6645 doi:10.1073/pnas.120163297
-
(2000)
Proc. Natl Acad. Sci. U.S.A.
, vol.97
, pp. 6640-6645
-
-
Datsenko, K.A.1
Wanner, B.L.2
-
28
-
-
38949155961
-
Pseudomonas aeruginosa PqsA is an anthranilate-coenzyme A ligase
-
Coleman, J.P., Hudson, L.L., McKnight, S.L., Farrow, III, J.M., Calfee, M.W., Lindsey, C.A. et al. (2008) Pseudomonas aeruginosa PqsA is an anthranilate-coenzyme A ligase. J. Bacteriol. 190, 1247–1255 doi:10.1128/JB.01140-07
-
(2008)
J. Bacteriol.
, vol.190
, pp. 1247-1255
-
-
Coleman, J.P.1
Hudson, L.L.2
McKnight, S.L.3
Farrow, J.M.4
Calfee, M.W.5
Lindsey, C.A.6
-
29
-
-
0030249023
-
Non-orthologous gene displacement
-
Koonin, E.V., Mushegian, A.R. and Bork, P. (1996) Non-orthologous gene displacement. Trends Genet. 12, 334–336 doi:10.1016/0168-9525(96)20010-1
-
(1996)
Trends Genet
, vol.12
, pp. 334-336
-
-
Koonin, E.V.1
Mushegian, A.R.2
Bork, P.3
-
30
-
-
0036407027
-
Suspected utility of enzymes with multiple activities in the small genome Mycoplasma species: The replacement of the missing ‘household’ nucleoside diphosphate kinase gene and activity by glycolytic kinases
-
Pollack, J.D., Myers, M.A., Dandekar, T. and Herrmann, R. (2002) Suspected utility of enzymes with multiple activities in the small genome Mycoplasma species: the replacement of the missing ‘household’ nucleoside diphosphate kinase gene and activity by glycolytic kinases. OMICS 6, 247–258 doi:10.1089/15362310260256909
-
(2002)
OMICS
, vol.6
, pp. 247-258
-
-
Pollack, J.D.1
Myers, M.A.2
Dandekar, T.3
Herrmann, R.4
-
31
-
-
0035717513
-
Nonorthologous gene displacement of phosphomevalonate kinase
-
Houten, S.M. and Waterham, H.R. (2001) Nonorthologous gene displacement of phosphomevalonate kinase. Mol. Genet. Metab. 72, 273–276 doi:10.1006/mgme.2000.3133
-
(2001)
Mol. Genet. Metab.
, vol.72
, pp. 273-276
-
-
Houten, S.M.1
Waterham, H.R.2
-
32
-
-
70350449245
-
Zinc-independent folate biosynthesis: Genetic, biochemical, and structural investigations reveal new metal dependence for GTP cyclohydrolase IB
-
Sankaran, B., Bonnett, S.A., Shah, K., Gabriel, S., Reddy, R., Schimmel, P. et al. (2009) Zinc-independent folate biosynthesis: genetic, biochemical, and structural investigations reveal new metal dependence for GTP cyclohydrolase IB. J. Bacteriol. 191, 6936–6949 doi:10.1128/JB.00287-09
-
(2009)
J. Bacteriol.
, vol.191
, pp. 6936-6949
-
-
Sankaran, B.1
Bonnett, S.A.2
Shah, K.3
Gabriel, S.4
Reddy, R.5
Schimmel, P.6
-
33
-
-
34447518986
-
A new thiamin salvage pathway
-
Jenkins, A.H., Schyns, G., Potot, S., Sun, G. and Begley, T.P. (2007) A new thiamin salvage pathway. Nat. Chem. Biol. 3, 492–497 doi:10.1038/nchembio.2007.13
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 492-497
-
-
Jenkins, A.H.1
Schyns, G.2
Potot, S.3
Sun, G.4
Begley, T.P.5
-
34
-
-
84907015131
-
Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine
-
Zallot, R., Yazdani, M., Goyer, A., Ziemak, M.J., Guan, J.-C., McCarty, D.R. et al. (2014) Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine. Biochem. J. 463, 145–155 doi:10.1042/BJ20140522
-
(2014)
Biochem. J.
, vol.463
, pp. 145-155
-
-
Zallot, R.1
Yazdani, M.2
Goyer, A.3
Ziemak, M.J.4
Guan, J.-C.5
McCarty, D.R.6
-
35
-
-
58149490653
-
A novel class of modular transporters for vitamins in prokaryotes
-
Rodionov, D.A., Hebbeln, P., Eudes, A., ter Beek, J., Rodionova, I.A., Erkens, G.B. et al. (2009) A novel class of modular transporters for vitamins in prokaryotes. J. Bacteriol. 191, 42–51 doi:10.1128/JB.01208-08
-
(2009)
J. Bacteriol.
, vol.191
, pp. 42-51
-
-
Rodionov, D.A.1
Hebbeln, P.2
Eudes, A.3
Ter Beek, J.4
Rodionova, I.A.5
Erkens, G.B.6
-
36
-
-
2242446202
-
Comparative genomics of thiamin biosynthesis in prokaryotes. New genes and regulatory mechanisms
-
Rodionov, D.A., Vitreschak, A.G., Mironov, A.A. and Gelfand, M.S. (2002) Comparative genomics of thiamin biosynthesis in prokaryotes. New genes and regulatory mechanisms. J. Biol. Chem. 277, 48949–48959 doi:10.1074/jbc.M208965200
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48949-48959
-
-
Rodionov, D.A.1
Vitreschak, A.G.2
Mironov, A.A.3
Gelfand, M.S.4
-
37
-
-
84896275530
-
Enzymatic and structural characterization of an archaeal thiamin phosphate synthase
-
Hayashi, M., Kobayashi, K., Esaki, H., Konno, H., Akaji, K., Tazuya, K. et al. (2014) Enzymatic and structural characterization of an archaeal thiamin phosphate synthase. Biochim. Biophys. Acta, Proteins Proteomics 1844, 803–809 doi:10.1016/j.bbapap.2014.02.017
-
(2014)
Biochim. Biophys. Acta, Proteins Proteomics
, vol.1844
, pp. 803-809
-
-
Hayashi, M.1
Kobayashi, K.2
Esaki, H.3
Konno, H.4
Akaji, K.5
Tazuya, K.6
-
38
-
-
0010607725
-
Reversal of aminopterin inhibition in Bacillus subtilis at the site of drug entry
-
PMID:14433044
-
Pine, M.J. (1960) Reversal of aminopterin inhibition in Bacillus subtilis at the site of drug entry. J. Bacteriol. 79, 835–840 PMID:14433044
-
(1960)
J. Bacteriol.
, vol.79
, pp. 835-840
-
-
Pine, M.J.1
-
39
-
-
84999006613
-
Does abiotic stress cause functional B vitamin deficiency in plants?
-
Hanson, A.D., Beaudoin, G.A., McCarty, D.R. and Gregory, III, J.F. (2016) Does abiotic stress cause functional B vitamin deficiency in plants? Plant Physiol. 172, 2082–2097 doi:10.1104/pp.16.01371
-
(2016)
Plant Physiol.
, vol.172
, pp. 2082-2097
-
-
Hanson, A.D.1
Beaudoin, G.A.2
McCarty, D.R.3
Gregory, J.F.4
-
40
-
-
0030842519
-
Identification and characterization of an operon in Salmonella typhimurium involved in thiamine biosynthesis
-
Petersen, L.A. and Downs, D.M. (1997) Identification and characterization of an operon in Salmonella typhimurium involved in thiamine biosynthesis. J. Bacteriol. 179, 4894–4900 doi:10.1128/jb.179.15.4894-4900.1997
-
(1997)
J. Bacteriol.
, vol.179
, pp. 4894-4900
-
-
Petersen, L.A.1
Downs, D.M.2
|