Action of the thiamine protagonist bacimethrin on thiamine biosynthesis

Journal of Bacteriology

Volumn 182, Issue 19, 2000, Pages 5606-5610

  Zilles, J L ^a   Croal, L R ^a   Downs, D M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACIMETHRIN; UNCLASSIFIED DRUG; 4 AMINO 5 (HYDROXYMETHYL) 2 METHYLPYRIMIDINE PHOSPHATE KINASE; 4-AMINO-5-(HYDROXYMETHYL)-2-METHYLPYRIMIDINE PHOSPHATE KINASE; BACTERIAL PROTEIN; CARRIER PROTEIN; ESCHERICHIA COLI PROTEIN; NUCLEOTIDYLTRANSFERASE; PHOSPHOTRANSFERASE; PYRIMIDINE DERIVATIVE; THIAMINE; THIC PROTEIN, BACTERIA; THIF PROTEIN, E COLI; THIG1 PROTEIN, E COLI;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIUM CULTURE; CULTURE MEDIUM; DRUG EFFECT; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; NONHUMAN; OPERON; PHENOTYPE; PRIORITY JOURNAL; SALMONELLA ENTERICA; VITAMIN METABOLISM; ANTIBIOTIC RESISTANCE; BIOSYNTHESIS; DRUG ANTAGONISM; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTAGENESIS;

BACTERIAL PROTEINS; CARRIER PROTEINS; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI PROTEINS; MUTAGENESIS; NUCLEOTIDYLTRANSFERASES; OPERON; PHENOTYPE; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); PYRIMIDINES; SALMONELLA ENTERICA; THIAMINE; TRANSCRIPTION, GENETIC;

EID: 0033623202     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.19.5606-5610.2000     Document Type: Article

References (33)

1. Evidence that rseC, a gene in the rpoE cluster, has a role in thiamine synthesis in Salmonella typhimurium
2. Thiamin synthesis in prokaryotes
3. The biosynthesis of folic acid. Inhibition by sulfonamides
4. Development of a trpE promoter-strength measuring system and its use in comparison of the trpEDCA, trpR and aroH promoters
5. Defects in pyruvate kinase cause a conditional increase of thiamine synthesis in Salmonella typhimurium
6. Lesions in the nuo operon, encoding NADH dehydrogenase complex I, prevent PurF-independent thiamine synthesis and reduce flux through the oxidative pentose phosphate pathway in Salmonella enterica serovar Typhimurium
7. Bacimethrin isolated from Streptomyces albus identification, derivatives, synthesis and biological properties
8. Involvement of the oxidative pentose phosphate pathway in thiamine biosynthesis in Salmonella typhimurium
9. Regulation of cobalamin biosynthetic operons in Salmonella typhimurium
10. The panE gene, encoding ketopantoate reductase, maps at 10 minutes and is allelic to apbA in Salmonella typhimurium
11. Reduced flux through the purine biosynthetic pathway results in an increased requirement for coenzyme A in thiamine synthesis in Salmonella enterica serovar Typhimurium
12. ApbA, the ketopantoate reductase enzyme of Salmonella typhimurium is required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway
13. Lesions in gshA (encoding γ-L-glutamyl-L-cystein synthetase) prevent aerobic synthesis of thiamine in Salmonella enterica serovar Typhimurium LT2
14. Genes of the Escherichia coli pur regulon are negatively controlled by a repressor-operator interaction
15. Localized mutagenesis of any specific small region of the bacterial chromosome
16. Role of hypoxanthine and guanine in regulation of Salmonella typhimurium pur gene expression
17. Genetic analysis of the histidine operon control region of Salmonella typhimurium
18. IscS is a sulfurtransferase for the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA
19. Leaky pantothenate and thiamin mutations of Salmonella typhimurium conferring sulphometuron methyl sensitivity
20. Utilization of sulfometuron methyl, an acetolactate synthase inhibitor, in molecular biological and metabolic studies of plants and microbes
21. Toxic accumulation of α-ketobutyrate caused by inhibition of the branched-chain amino acid biosynthetic enzyme acetolactate synthase in Salmonella typhimurium
22. pACYC184-derived cloning vectors containing the multiple cloning site and lacAa reporter gene of pUC8/9 and pUC18/19 plasmids
23. Glutamine phosphoribosyl pyrophosphate amidotransferase from Escherichia coli
24. Identification of an operon in Salmonella typhimurium involved in thiamine biosynthesis
25. Mutations in apbC (mrp) prevent function of the alternative pyrimidine biosynthetic pathway in Salmonella typhimurium
26. Genetic analysis of metabolic crosstalk and its impact on thiamine synthesis in Salmonella typhimurium
27. Overexpression, purification and characterization of two phyrimidne kinase involved in the biosynthesis of thiamin; 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase
28. Phenotypic characterization of mutants defective in the isc locus of Salmonella enterica serovar Typhimurium: Implications for thiamine synthesis
29. Bacimethrin, a new antibiotic produced by B. megatherium
30. Structural genes for thiamine biosynthetic enzymes (thiCEFGH) in Escherichia coli K-12
31. 6) kinase in Escherichia coli K-12
32. Biosynthesis of purine nucleotides