메뉴 건너뛰기




Volumn 3, Issue 8, 2017, Pages 559-563

The Challenge of Overcoming Antibiotic Resistance: An Adjuvant Approach?

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; PHARMACEUTICAL VEHICLES AND ADDITIVES;

EID: 85027284569     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.7b00071     Document Type: Article
Times cited : (181)

References (53)
  • 2
    • 85027267133 scopus 로고    scopus 로고
    • World Health Organization. AntimicrobialResistance - Global Report on Surveillance
    • World Health Organization. AntimicrobialResistance-Global Report on Surveillance, (2014.
    • (2014)
  • 3
    • 85010399975 scopus 로고    scopus 로고
    • Notes from the Field: Pan-Resistant New Delhi Metallo-Beta-Lactamase-Producing Klebsiella pneumoniae - Washoe County, Nevada, 2016
    • Chen, L., Todd, R., Kiehlbauch, J., Walters, M., and Kallen, A. (2017) Notes from the Field: Pan-Resistant New Delhi Metallo-Beta-Lactamase-Producing Klebsiella pneumoniae-Washoe County, Nevada, 2016 MMWR Morb. Mortal. Wkly. Rep. 66 (1) 33 10.15585/mmwr.mm6601a7
    • (2017) MMWR Morb. Mortal. Wkly. Rep. , vol.66 , Issue.1 , pp. 33
    • Chen, L.1    Todd, R.2    Kiehlbauch, J.3    Walters, M.4    Kallen, A.5
  • 8
    • 85019621483 scopus 로고    scopus 로고
    • The antibiotic resistance crisis, with a focus on the United States
    • Martens, E. and Demain, A. L. (2017) The antibiotic resistance crisis, with a focus on the United States J. Antibiot. 70, 520 10.1038/ja.2017.30
    • (2017) J. Antibiot. , vol.70 , pp. 520
    • Martens, E.1    Demain, A.L.2
  • 9
    • 84926291696 scopus 로고    scopus 로고
    • The antibiotic resistance crisis: Part 1: Causes and threats
    • Ventola, C. L. (2015) The antibiotic resistance crisis: part 1: causes and threats P&T Community 40 (4) 277-283
    • (2015) P&T Community , vol.40 , Issue.4 , pp. 277-283
    • Ventola, C.L.1
  • 10
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: Confronting the challenges of antibacterial discovery
    • Payne, D. J., Gwynn, M. N., Holmes, D. J., and Pompliano, D. L. (2007) Drugs for bad bugs: confronting the challenges of antibacterial discovery Nat. Rev. Drug Discovery 6 (1) 29-40 10.1038/nrd2201
    • (2007) Nat. Rev. Drug Discovery , vol.6 , Issue.1 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 11
    • 84955461306 scopus 로고    scopus 로고
    • Antibacterial drug discovery in the resistance era
    • Brown, E. D. and Wright, G. D. (2016) Antibacterial drug discovery in the resistance era Nature 529 (7586) 336-343 10.1038/nature17042
    • (2016) Nature , vol.529 , Issue.7586 , pp. 336-343
    • Brown, E.D.1    Wright, G.D.2
  • 12
    • 84929762051 scopus 로고    scopus 로고
    • Antibiotics: The changing regulatory and pharmaceutical industry paradigm
    • Bax, R. and Green, S. (2015) Antibiotics: the changing regulatory and pharmaceutical industry paradigm J. Antimicrob. Chemother. 70 (5) 1281-1284 10.1093/jac/dku572
    • (2015) J. Antimicrob. Chemother. , vol.70 , Issue.5 , pp. 1281-1284
    • Bax, R.1    Green, S.2
  • 14
    • 84994518759 scopus 로고    scopus 로고
    • Antibiotic Adjuvants: Rescuing Antibiotics from Resistance
    • Wright, G. D. (2016) Antibiotic Adjuvants: Rescuing Antibiotics from Resistance Trends Microbiol. 24 (11) 862-871 10.1016/j.tim.2016.06.009
    • (2016) Trends Microbiol. , vol.24 , Issue.11 , pp. 862-871
    • Wright, G.D.1
  • 15
    • 84867332729 scopus 로고    scopus 로고
    • Adjuvant strategies for potentiation of antibiotics to overcome antimicrobial resistance
    • Pieren, M. and Tigges, M. (2012) Adjuvant strategies for potentiation of antibiotics to overcome antimicrobial resistance Curr. Opin. Pharmacol. 12 (5) 551-5555 10.1016/j.coph.2012.07.005
    • (2012) Curr. Opin. Pharmacol. , vol.12 , Issue.5 , pp. 551-5555
    • Pieren, M.1    Tigges, M.2
  • 16
    • 66949152183 scopus 로고    scopus 로고
    • Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center
    • Hartzell, J. D., Neff, R., Ake, J., Howard, R., Olson, S., Paolino, K., Vishnepolsky, M., Weintrob, A., and Wortmann, G. (2009) Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center Clin. Infect. Dis. 48 (12) 1724-1728 10.1086/599225
    • (2009) Clin. Infect. Dis. , vol.48 , Issue.12 , pp. 1724-1728
    • Hartzell, J.D.1    Neff, R.2    Ake, J.3    Howard, R.4    Olson, S.5    Paolino, K.6    Vishnepolsky, M.7    Weintrob, A.8    Wortmann, G.9
  • 17
    • 75949092121 scopus 로고    scopus 로고
    • Anti-virulence strategies to combat bacteria-mediated disease
    • Rasko, D. A. and Sperandio, V. (2010) Anti-virulence strategies to combat bacteria-mediated disease Nat. Rev. Drug Discovery 9 (2) 117-128 10.1038/nrd3013
    • (2010) Nat. Rev. Drug Discovery , vol.9 , Issue.2 , pp. 117-128
    • Rasko, D.A.1    Sperandio, V.2
  • 18
    • 84900443098 scopus 로고    scopus 로고
    • Small Molecule Downregulation of PmrAB Reverses Lipid A Modification and Breaks Colistin Resistance
    • Harris, T. L., Worthington, R. J., Hittle, L. E., Zurawski, D. V., Ernst, R. K., and Melander, C. (2014) Small Molecule Downregulation of PmrAB Reverses Lipid A Modification and Breaks Colistin Resistance ACS Chem. Biol. 9 (1) 122-127 10.1021/cb400490k
    • (2014) ACS Chem. Biol. , vol.9 , Issue.1 , pp. 122-127
    • Harris, T.L.1    Worthington, R.J.2    Hittle, L.E.3    Zurawski, D.V.4    Ernst, R.K.5    Melander, C.6
  • 19
    • 84875212396 scopus 로고    scopus 로고
    • Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance
    • Palmer, A. C. and Kishony, R. (2013) Understanding, predicting and manipulating the genotypic evolution of antibiotic resistance Nat. Rev. Genet. 14 (4) 243-248 10.1038/nrg3351
    • (2013) Nat. Rev. Genet. , vol.14 , Issue.4 , pp. 243-248
    • Palmer, A.C.1    Kishony, R.2
  • 20
    • 84861116576 scopus 로고    scopus 로고
    • The chemotherapy of tuberculosis: Past, present and future
    • Mitchison, D. and Davies, G. (2012) The chemotherapy of tuberculosis: past, present and future Int. J. Tuberc Lung Dis 16 (6) 724-732 10.5588/ijtld.12.0083
    • (2012) Int. J. Tuberc Lung Dis , vol.16 , Issue.6 , pp. 724-732
    • Mitchison, D.1    Davies, G.2
  • 21
    • 80053901787 scopus 로고    scopus 로고
    • Combination therapies for combating antimicrobial resistance
    • Fischbach, M. A. (2011) Combination therapies for combating antimicrobial resistance Curr. Opin. Microbiol. 14 (5) 519-523 10.1016/j.mib.2011.08.003
    • (2011) Curr. Opin. Microbiol. , vol.14 , Issue.5 , pp. 519-523
    • Fischbach, M.A.1
  • 22
    • 84863654489 scopus 로고    scopus 로고
    • Combination therapy for treatment of infections with gram-negative bacteria
    • Tamma, P. D., Cosgrove, S. E., and Maragakis, L. L. (2012) Combination therapy for treatment of infections with gram-negative bacteria Clin Microbiol Rev. 25 (3) 450-70 10.1128/CMR.05041-11
    • (2012) Clin Microbiol Rev. , vol.25 , Issue.3 , pp. 450-470
    • Tamma, P.D.1    Cosgrove, S.E.2    Maragakis, L.L.3
  • 23
    • 50149096410 scopus 로고    scopus 로고
    • Colistin monotherapy vs. Combination therapy: Evidence from microbiological, animal and clinical studies
    • Petrosillo, N., Ioannidou, E., and Falagas, M. E. (2008) Colistin monotherapy vs. combination therapy: evidence from microbiological, animal and clinical studies Clin. Microbiol. Infect. 14 (9) 816-827 10.1111/j.1469-0691.2008.02061.x
    • (2008) Clin. Microbiol. Infect. , vol.14 , Issue.9 , pp. 816-827
    • Petrosillo, N.1    Ioannidou, E.2    Falagas, M.E.3
  • 24
    • 84896968084 scopus 로고    scopus 로고
    • New beta-lactamase inhibitors: A therapeutic renaissance in an MDR world
    • Drawz, S. M., Papp-Wallace, K. M., and Bonomo, R. A. (2014) New beta-lactamase inhibitors: a therapeutic renaissance in an MDR world Antimicrob. Agents Chemother. 58 (4) 1835-1846 10.1128/AAC.00826-13
    • (2014) Antimicrob. Agents Chemother. , vol.58 , Issue.4 , pp. 1835-1846
    • Drawz, S.M.1    Papp-Wallace, K.M.2    Bonomo, R.A.3
  • 25
    • 84991290250 scopus 로고    scopus 로고
    • New beta-Lactamase Inhibitors in the Clinic
    • Papp-Wallace, K. M. and Bonomo, R. A. (2016) New beta-Lactamase Inhibitors in the Clinic Infect Dis Clin North Am. 30 (2) 441-464 10.1016/j.idc.2016.02.007
    • (2016) Infect Dis Clin North Am. , vol.30 , Issue.2 , pp. 441-464
    • Papp-Wallace, K.M.1    Bonomo, R.A.2
  • 26
    • 74249108028 scopus 로고    scopus 로고
    • Three decades of beta-lactamase inhibitors
    • Drawz, S. M. and Bonomo, R. A. (2010) Three decades of beta-lactamase inhibitors Clin Microbiol Rev. 23 (1) 160-201 10.1128/CMR.00037-09
    • (2010) Clin Microbiol Rev. , vol.23 , Issue.1 , pp. 160-201
    • Drawz, S.M.1    Bonomo, R.A.2
  • 27
    • 84946567642 scopus 로고    scopus 로고
    • A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens
    • Bush, K. (2015) A resurgence of beta-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens Int. J. Antimicrob. Agents 46 (5) 483-493 10.1016/j.ijantimicag.2015.08.011
    • (2015) Int. J. Antimicrob. Agents , vol.46 , Issue.5 , pp. 483-493
    • Bush, K.1
  • 29
    • 78650195466 scopus 로고    scopus 로고
    • Aminoglycoside modifying enzymes
    • Ramirez, M. S. and Tolmasky, M. E. (2010) Aminoglycoside modifying enzymes Drug Resist. Updates 13 (6) 151-71 10.1016/j.drup.2010.08.003
    • (2010) Drug Resist. Updates , vol.13 , Issue.6 , pp. 151-171
    • Ramirez, M.S.1    Tolmasky, M.E.2
  • 30
    • 84893427971 scopus 로고    scopus 로고
    • Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections
    • Labby, K. J. and Garneau-Tsodikova, S. (2013) Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections Future Med. Chem. 5 (11) 1285-1309 10.4155/fmc.13.80
    • (2013) Future Med. Chem. , vol.5 , Issue.11 , pp. 1285-1309
    • Labby, K.J.1    Garneau-Tsodikova, S.2
  • 31
    • 22144476125 scopus 로고    scopus 로고
    • Bacterial resistance to antibiotics: Enzymatic degradation and modification
    • Wright, G. D. (2005) Bacterial resistance to antibiotics: enzymatic degradation and modification Adv. Drug Delivery Rev. 57 (10) 1451-1470 10.1016/j.addr.2005.04.002
    • (2005) Adv. Drug Delivery Rev. , vol.57 , Issue.10 , pp. 1451-1470
    • Wright, G.D.1
  • 32
    • 4544361918 scopus 로고    scopus 로고
    • Macrolide resistance based on the Erm-mediated rRNA methylation
    • Maravic, G. (2004) Macrolide resistance based on the Erm-mediated rRNA methylation Curr. Drug Targets: Infect. Disord. 4 (3) 193-202 10.2174/1568005043340777
    • (2004) Curr. Drug Targets: Infect. Disord. , vol.4 , Issue.3 , pp. 193-202
    • Maravic, G.1
  • 33
    • 84908457716 scopus 로고    scopus 로고
    • Bacterial multidrug efflux pumps: Mechanisms, physiology and pharmacological exploitations
    • Sun, J., Deng, Z., and Yan, A. (2014) Bacterial multidrug efflux pumps: mechanisms, physiology and pharmacological exploitations Biochem. Biophys. Res. Commun. 453 (2) 254-267 10.1016/j.bbrc.2014.05.090
    • (2014) Biochem. Biophys. Res. Commun. , vol.453 , Issue.2 , pp. 254-267
    • Sun, J.1    Deng, Z.2    Yan, A.3
  • 35
    • 0025667590 scopus 로고
    • Antibiotic uptake and transport by bacteria
    • Livermore, D. M. (1990) Antibiotic uptake and transport by bacteria Scand. J. Infect. Dis. Suppl. 74, 15-22
    • (1990) Scand. J. Infect. Dis. Suppl. , vol.74 , pp. 15-22
    • Livermore, D.M.1
  • 36
    • 0036096326 scopus 로고    scopus 로고
    • Cellular impermeability and uptake of biocides and antibiotics in Gram-positive bacteria and mycobacteria
    • Lambert, P. A. (2002) Cellular impermeability and uptake of biocides and antibiotics in Gram-positive bacteria and mycobacteria J. Appl. Microbiol. 92 (Suppl.) 46S-54S 10.1046/j.1365-2672.92.5s1.7.x
    • (2002) J. Appl. Microbiol. , vol.92 , pp. 46S-54S
    • Lambert, P.A.1
  • 38
    • 84969597463 scopus 로고    scopus 로고
    • Treatment of Gram-negative bacterial infections by potentiation of antibiotics
    • Zabawa, T. P., Pucci, M. J., Parr, T. R., Jr., and Lister, T. (2016) Treatment of Gram-negative bacterial infections by potentiation of antibiotics Curr. Opin. Microbiol. 33, 7-12 10.1016/j.mib.2016.05.005
    • (2016) Curr. Opin. Microbiol. , vol.33 , pp. 7-12
    • Zabawa, T.P.1    Pucci, M.J.2    Parr, Jr.T.R.3    Lister, T.4
  • 39
    • 84969269067 scopus 로고    scopus 로고
    • Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and Its Abrogation by Small Molecules
    • Boudreau, M. A., Fishovitz, J., Llarrull, L. I., Xiao, Q. B., and Mobashery, S. (2015) Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and Its Abrogation by Small Molecules ACS Infect. Dis. 1 (10) 454-459 10.1021/acsinfecdis.5b00086
    • (2015) ACS Infect. Dis. , vol.1 , Issue.10 , pp. 454-459
    • Boudreau, M.A.1    Fishovitz, J.2    Llarrull, L.I.3    Xiao, Q.B.4    Mobashery, S.5
  • 40
    • 84965113547 scopus 로고    scopus 로고
    • RecA Inhibitors Potentiate Antibiotic Activity and Block Evolution of Antibiotic Resistance
    • Alam, M. K., Alhhazmi, A., DeCoteau, J. F., Luo, Y., and Geyer, C. R. (2016) RecA Inhibitors Potentiate Antibiotic Activity and Block Evolution of Antibiotic Resistance Cell Chem. Biol. 23 (3) 381-391 10.1016/j.chembiol.2016.02.010
    • (2016) Cell Chem. Biol. , vol.23 , Issue.3 , pp. 381-391
    • Alam, M.K.1    Alhhazmi, A.2    DeCoteau, J.F.3    Luo, Y.4    Geyer, C.R.5
  • 41
    • 84892980568 scopus 로고    scopus 로고
    • Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence
    • Worthington, R. J., Blackledge, M. S., and Melander, C. (2013) Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence Future Med. Chem. 5 (11) 1265-1284 10.4155/fmc.13.58
    • (2013) Future Med. Chem. , vol.5 , Issue.11 , pp. 1265-1284
    • Worthington, R.J.1    Blackledge, M.S.2    Melander, C.3
  • 42
    • 84865687625 scopus 로고    scopus 로고
    • Small molecule control of bacterial biofilms
    • Worthington, R. J., Richards, J. J., and Melander, C. (2012) Small molecule control of bacterial biofilms Org. Biomol. Chem. 10 (37) 7457-74 10.1039/c2ob25835h
    • (2012) Org. Biomol. Chem. , vol.10 , Issue.37 , pp. 7457-7474
    • Worthington, R.J.1    Richards, J.J.2    Melander, C.3
  • 43
    • 84957593042 scopus 로고    scopus 로고
    • The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release
    • Brackman, G., Breyne, K., De Rycke, R., Vermote, A., Van Nieuwerburgh, F., Meyer, E., Van Calenbergh, S., and Coenye, T. (2016) The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release Sci. Rep. 6, 20321 10.1038/srep20321
    • (2016) Sci. Rep. , vol.6 , pp. 20321
    • Brackman, G.1    Breyne, K.2    De Rycke, R.3    Vermote, A.4    Van Nieuwerburgh, F.5    Meyer, E.6    Van Calenbergh, S.7    Coenye, T.8
  • 44
    • 67650708892 scopus 로고    scopus 로고
    • Importance of DNase and alginate lyase for enhancing free and liposome encapsulated aminoglycoside activity against Pseudomonas aeruginosa
    • Alipour, M., Suntres, Z. E., and Omri, A. (2009) Importance of DNase and alginate lyase for enhancing free and liposome encapsulated aminoglycoside activity against Pseudomonas aeruginosa J. Antimicrob. Chemother. 64 (2) 317-325 10.1093/jac/dkp165
    • (2009) J. Antimicrob. Chemother. , vol.64 , Issue.2 , pp. 317-325
    • Alipour, M.1    Suntres, Z.E.2    Omri, A.3
  • 45
    • 0029945042 scopus 로고    scopus 로고
    • The role of dornase alfa in the treatment of cystic fibrosis
    • Cramer, G. W. and Bosso, J. A. (1996) The role of dornase alfa in the treatment of cystic fibrosis Ann. Pharmacother 30 (6) 656-661 10.1177/106002809603000614
    • (1996) Ann. Pharmacother , vol.30 , Issue.6 , pp. 656-661
    • Cramer, G.W.1    Bosso, J.A.2
  • 46
    • 33845607284 scopus 로고    scopus 로고
    • Persister cells, dormancy and infectious disease
    • Lewis, K. (2007) Persister cells, dormancy and infectious disease Nat. Rev. Microbiol. 5 (1) 48-56 10.1038/nrmicro1557
    • (2007) Nat. Rev. Microbiol. , vol.5 , Issue.1 , pp. 48-56
    • Lewis, K.1
  • 48
    • 84868149433 scopus 로고    scopus 로고
    • A Forward Chemical Screen Identifies Antibiotic Adjuvants in Escherichia coli
    • Taylor, P. L., Rossi, L., De Pascale, G., and Wright, G. D. (2012) A Forward Chemical Screen Identifies Antibiotic Adjuvants in Escherichia coli ACS Chem. Biol. 7 (9) 1547-1555 10.1021/cb300269g
    • (2012) ACS Chem. Biol. , vol.7 , Issue.9 , pp. 1547-1555
    • Taylor, P.L.1    Rossi, L.2    De Pascale, G.3    Wright, G.D.4
  • 49
    • 34547770279 scopus 로고    scopus 로고
    • New uses for old drugs
    • Chong, C. R. and Sullivan, D. J., Jr. (2007) New uses for old drugs Nature 448 (7154) 645-646 10.1038/448645a
    • (2007) Nature , vol.448 , Issue.7154 , pp. 645-646
    • Chong, C.R.1    Sullivan, Jr.D.J.2
  • 50
    • 79955079817 scopus 로고    scopus 로고
    • Genome-scale identification of resistance functions in Pseudomonas aeruginosa using Tn-seq
    • Gallagher, L. A., Shendure, J., and Manoil, C. (2011) Genome-scale identification of resistance functions in Pseudomonas aeruginosa using Tn-seq MBio 2 (1) e00315-10 10.1128/mBio.00315-10
    • (2011) MBio , vol.2 , Issue.1 , pp. e00315-e00410
    • Gallagher, L.A.1    Shendure, J.2    Manoil, C.3
  • 51
    • 82255181188 scopus 로고    scopus 로고
    • Antagonism of chemical genetic interaction networks resensitize MRSA to beta-lactam antibiotics
    • Lee, S. H., Jarantow, L. W., Wang, H., Sillaots, S., Cheng, H., Meredith, T. C., Thompson, J., and Roemer, T. (2011) Antagonism of chemical genetic interaction networks resensitize MRSA to beta-lactam antibiotics Chem. Biol. 18 (11) 1379-1389 10.1016/j.chembiol.2011.08.015
    • (2011) Chem. Biol. , vol.18 , Issue.11 , pp. 1379-1389
    • Lee, S.H.1    Jarantow, L.W.2    Wang, H.3    Sillaots, S.4    Cheng, H.5    Meredith, T.C.6    Thompson, J.7    Roemer, T.8
  • 52
    • 33747494199 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of truncated bisubstrate inhibitors of aminoglycoside 6′-N-acetyltransferases
    • Gao, F., Yan, X., Shakya, T., Baettig, O. M., Ait-Mohand-Brunet, S., Berghuis, A. M., Wright, G. D., and Auclair, K. (2006) Synthesis and structure-activity relationships of truncated bisubstrate inhibitors of aminoglycoside 6′-N-acetyltransferases J. Med. Chem. 49 (17) 5273-5281 10.1021/jm060732n
    • (2006) J. Med. Chem. , vol.49 , Issue.17 , pp. 5273-5281
    • Gao, F.1    Yan, X.2    Shakya, T.3    Baettig, O.M.4    Ait-Mohand-Brunet, S.5    Berghuis, A.M.6    Wright, G.D.7    Auclair, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.