메뉴 건너뛰기




Volumn , Issue , 2013, Pages 137-182

Toxicogenomics: Techniques, Applications, and Challenges

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85026927361     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/b14289-11     Document Type: Chapter
Times cited : (1)

References (45)
  • 1
    • 0033104629 scopus 로고    scopus 로고
    • Three machine learning techniques for automatic determination of rules to control locomotion
    • Jonic, S., T. Jankovic, V. Gajic, and D. Popovic. 1999. Three machine learning techniques for automatic determination of rules to control locomotion. IEEE Transactions on Biomedical Engineering 46:300-310.
    • (1999) IEEE Transactions on Biomedical Engineering , vol.46 , pp. 300-310
    • Jonic, S.1    Jankovic, T.2    Gajic, V.3    Popovic, D.4
  • 2
    • 0036153531 scopus 로고    scopus 로고
    • The National Center for Toxicogenomics: Using new technologies to inform mechanistic toxicology
    • Tennant, R.W. 2002. The National Center for Toxicogenomics: Using new technologies to inform mechanistic toxicology. Environmental Health Perspectives 110:A8-A10.
    • (2002) Environmental Health Perspectives , vol.110 , pp. A8-A10
    • Tennant, R.W.1
  • 3
    • 0033168968 scopus 로고    scopus 로고
    • LightCycler technology for the quantitation of bcr/abl fusion transcripts
    • Kreuzer, K.A., U. Lass, A. Bohn, O. Landt, and C.A. Schmidt. 1999. LightCycler technology for the quantitation of bcr/abl fusion transcripts. Cancer Research 59:3171-3174.
    • (1999) Cancer Research , vol.59 , pp. 3171-3174
    • Kreuzer, K.A.1    Lass, U.2    Bohn, A.3    Landt, O.4    Schmidt, C.A.5
  • 4
    • 84984932472 scopus 로고    scopus 로고
    • Exploring the new world of the genome with DNA microarrays
    • Brown, P.O., and D. Botstein. 1999. Exploring the new world of the genome with DNA microarrays. Nature Genetics 21:33-37.
    • (1999) Nature Genetics , vol.21 , pp. 33-37
    • Brown, P.O.1    Botstein, D.2
  • 5
    • 0037311919 scopus 로고    scopus 로고
    • TM4: A free, open-source system for microarray data management and analysis
    • Saeed, A.I., V. Sharov, J. White, J. Li, W. Liang, N. Bhagabati et al. 2003. TM4: A free, open-source system for microarray data management and analysis. Biotechniques 374-378.
    • (2003) Biotechniques , vol.4 , pp. 374-378
    • Saeed, A.I.1    Sharov, V.2    White, J.3    Li, J.4    Liang, W.5    Bhagabati, N.6
  • 6
    • 18144425478 scopus 로고    scopus 로고
    • A genome-wide scalable SNP genotyping assay using microarray technology
    • Gunderson, K.L., F.J. Steemers, G. Lee, L.G. Mendoza, and M.S. Chee. 2005. A genome-wide scalable SNP genotyping assay using microarray technology. Nature Genetics 37(5):549-554.
    • (2005) Nature Genetics , vol.37 , Issue.5 , pp. 549-554
    • Gunderson, K.L.1    Steemers, F.J.2    Lee, G.3    Mendoza, L.G.4    Chee, M.S.5
  • 7
  • 9
    • 67651002343 scopus 로고    scopus 로고
    • Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
    • Sotiropoulou, G., G. Pampalakis, E. Lianidou, and Z. Mourelatos. 2009. Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell. RNA 15:1443-1461.
    • (2009) RNA , vol.15 , pp. 1443-1461
    • Sotiropoulou, G.1    Pampalakis, G.2    Lianidou, E.3    Mourelatos, Z.4
  • 10
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • Aebersold, R., and M. Mann. 2003. Mass spectrometry-based proteomics. Nature 422(6928): 198-207.
    • (2003) Nature , vol.422 , Issue.6928 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 11
    • 0042420888 scopus 로고    scopus 로고
    • Mapping protein modifications with liquid chromatography-mass spectrometry and the SALSA algorithm
    • Liebler, D.C., B.T. Hansen, J.A. Jones, H. Badghisi, and D.E. Mason. 2003. Mapping protein modifications with liquid chromatography-mass spectrometry and the SALSA algorithm. Advances in Protein Chemistry 65:195-216.
    • (2003) Advances in Protein Chemistry , vol.65 , pp. 195-216
    • Liebler, D.C.1    Hansen, B.T.2    Jones, J.A.3    Badghisi, H.4    Mason, D.E.5
  • 12
    • 0031553992 scopus 로고    scopus 로고
    • Isoelectric focusing in immobilized pH gradients: Recent analytical and preparative developments
    • Righetti, P.G., and A. Bossi. 1997. Isoelectric focusing in immobilized pH gradients: Recent analytical and preparative developments. Analytical Biochemistry 247(1):1-10.
    • (1997) Analytical Biochemistry , vol.247 , Issue.1 , pp. 1-10
    • Righetti, P.G.1    Bossi, A.2
  • 13
    • 0035491770 scopus 로고    scopus 로고
    • Fluorescent dual colour 2D-protein gel electrophoresis for rapid detection of differences in protein pattern with standard image analysis software
    • Von Eggeling, F., A. Gawriljuk, W. Fiedler, G. Ernst, U. Claussen, J. Klose et al. 2001. Fluorescent dual colour 2D-protein gel electrophoresis for rapid detection of differences in protein pattern with standard image analysis software. International Journal of Molecular Medicine 8(4):373-377.
    • (2001) International Journal of Molecular Medicine , vol.8 , Issue.4 , pp. 373-377
    • Von Eggeling, F.1    Gawriljuk, A.2    Fiedler, W.3    Ernst, G.4    Claussen, U.5    Klose, J.6
  • 15
    • 0036935333 scopus 로고    scopus 로고
    • Altered protein profile and possible hypoxia in the placenta of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin exposed rats
    • Ishimura, R., S. Ohsako, T. Kawakami, M. Sakaue, T. Aoki, and C. Tohyama. 2002. Altered protein profile and possible hypoxia in the placenta of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin exposed rats. Toxicology and Applied Pharmacology 185(3):197-206.
    • (2002) Toxicology and Applied Pharmacology , vol.185 , Issue.3 , pp. 197-206
    • Ishimura, R.1    Ohsako, S.2    Kawakami, T.3    Sakaue, M.4    Aoki, T.5    Tohyama, C.6
  • 16
    • 5644221313 scopus 로고    scopus 로고
    • Molecular classification of liver cirrhosis in a rat model by proteomics and bioinformatics
    • Xu, X.Q., C.K. Leow, X. Lu, X. Zhang, and J.S. Liu. 2004. Molecular classification of liver cirrhosis in a rat model by proteomics and bioinformatics. Proteomics 4(10):3235-3245.
    • (2004) Proteomics , vol.4 , Issue.10 , pp. 3235-3245
    • Xu, X.Q.1    Leow, C.K.2    Lu, X.3    Zhang, X.4    Liu, J.S.5
  • 17
    • 0035582244 scopus 로고    scopus 로고
    • An automated multi-dimensional protein identification technology for shotgun proteomics
    • Wolters, D.A., M.P. Washburn, and Y.R. Yates, III. 2001. An automated multi-dimensional protein identification technology for shotgun proteomics. Analytical Chemistry 73(23):5683-5690.
    • (2001) Analytical Chemistry , vol.73 , Issue.23 , pp. 5683-5690
    • Wolters, D.A.1    Washburn, M.P.2    Yates, Y.R.3
  • 18
    • 0036535357 scopus 로고    scopus 로고
    • Analysis of quantitative proteomic data generated via multidimensional protein identification technology
    • Washburn, M.P., R. Ulaszek, R. Deciu, D.M. Schieltz, and J.R. Yates, III. 2002. Analysis of quantitative proteomic data generated via multidimensional protein identification technology. Analytical Chemistry 74(7):1650-1657.
    • (2002) Analytical Chemistry , vol.74 , Issue.7 , pp. 1650-1657
    • Washburn, M.P.1    Ulaszek, R.2    Deciu, R.3    Schieltz, D.M.4    Yates, J.R.5
  • 20
    • 0033795182 scopus 로고    scopus 로고
    • Metabonomics: Evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants
    • Robertson, D.G., M.D. Reily, R.E. Sigler, D.F. Wells, D.A. Paterson, and T.K. Braden. 2000. Metabonomics: Evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants. Toxicology Science 57:326-337.
    • (2000) Toxicology Science , vol.57 , pp. 326-337
    • Robertson, D.G.1    Reily, M.D.2    Sigler, R.E.3    Wells, D.F.4    Paterson, D.A.5    Braden, T.K.6
  • 22
    • 0344823665 scopus 로고    scopus 로고
    • Toxicogenomic approach for assessing toxicant-related disease
    • Waters, M.D., K. Olden, and R.W. Tennant. 2003. Toxicogenomic approach for assessing toxicant-related disease. Mutation Research 544:415-424.
    • (2003) Mutation Research , vol.544 , pp. 415-424
    • Waters, M.D.1    Olden, K.2    Tennant, R.W.3
  • 23
    • 0035107971 scopus 로고    scopus 로고
    • Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks
    • Holmes, E., J.K. Nicholson, and G. Tranter. 2001. Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks. Chemical Research in Toxicology 14:182-191.
    • (2001) Chemical Research in Toxicology , vol.14 , pp. 182-191
    • Holmes, E.1    Nicholson, J.K.2    Tranter, G.3
  • 24
    • 3042785758 scopus 로고    scopus 로고
    • Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets
    • Stoyanova, R., J.K. Nicholson, J.C. Lindon, and T.R. Brown. 2004. Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets. Analytical Chemistry 76(13):3666-3674.
    • (2004) Analytical Chemistry , vol.76 , Issue.13 , pp. 3666-3674
    • Stoyanova, R.1    Nicholson, J.K.2    Lindon, J.C.3    Brown, T.R.4
  • 25
    • 3142661160 scopus 로고    scopus 로고
    • An integrated reverse functional genomics and metabolic approach to understanding orotic acid-induced fatty liver
    • Griffin, J.L., S.A. Bonney, A. Mann, A.M. Hebbachi, and G.F Gibbons. 2001. An integrated reverse functional genomics and metabolic approach to understanding orotic acid-induced fatty liver. Physiology Genomics 17(2):140-149.
    • (2001) Physiology Genomics , vol.17 , Issue.2 , pp. 140-149
    • Griffin, J.L.1    Bonney, S.A.2    Mann, A.3    Hebbachi, A.M.4    Gibbons, G.F.5
  • 27
    • 0037444362 scopus 로고    scopus 로고
    • Contemporary issues in toxicology: The role of metabonomics in toxicology and its evaluation by the COMET project
    • Lindon, J.C. 2003. Contemporary issues in toxicology: The role of metabonomics in toxicology and its evaluation by the COMET project. Toxicology and Applied Pharmacology 187:137-146.
    • (2003) Toxicology and Applied Pharmacology , vol.187 , pp. 137-146
    • Lindon, J.C.1
  • 30
    • 34548616496 scopus 로고    scopus 로고
    • Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia
    • Lum, P.Y., Y.D. He, J.G. Slatter, J.F. Waring, and N. Zelinsky 2007. Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia. Genomics 90:464-473.
    • (2007) Genomics , vol.90 , pp. 464-473
    • Lum, P.Y.1    He, Y.D.2    Slatter, J.G.3    Waring, J.F.4    Zelinsky, N.5
  • 31
    • 24644440225 scopus 로고    scopus 로고
    • Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals
    • Stierum, R., W. Heijne, A. Kienhuis, B. van Ommen, and J. Groten. 2005. Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals. Toxicology and Applied Pharmacology 207(2 Suppl):179-188.
    • (2005) Toxicology and Applied Pharmacology , vol.207 , Issue.2 , pp. 179-188
    • Stierum, R.1    Heijne, W.2    Kienhuis, A.3    van Ommen, B.4    Groten, J.5
  • 32
    • 0001877251 scopus 로고    scopus 로고
    • Chemical carcinogenesis
    • edited by Klaassen, C.D., New York: McGraw-Hill Companies Inc
    • Pitot, III H.C., and Y.P. Dragan. 2001. Chemical carcinogenesis. In Casarett and Doull’s Toxicology, edited by Klaassen, C.D., vol. 6:266-280. New York: McGraw-Hill Companies Inc.
    • (2001) Casarett and Doull’s Toxicology , vol.6 , pp. 266-280
    • Pitot, H.C.1    Dragan, Y.P.2
  • 34
    • 0030028664 scopus 로고    scopus 로고
    • Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis and is blocked by insulin-like growth factor II
    • Ueda, K., and D. Ganem. 1996. Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis and is blocked by insulin-like growth factor II. Journal of Virology 70:1375-1383.
    • (1996) Journal of Virology , vol.70 , pp. 1375-1383
    • Ueda, K.1    Ganem, D.2
  • 36
  • 39
    • 0034251950 scopus 로고    scopus 로고
    • The alcohol-inducible form of cytochrome P450 (CYP 2E1): Role in toxicology and regulation of expression
    • Novak, R.F., and K.J. Woodcroft. 2000. The alcohol-inducible form of cytochrome P450 (CYP 2E1): Role in toxicology and regulation of expression. Archives of Pharmaceutical Research 23:267-282.
    • (2000) Archives of Pharmaceutical Research , vol.23 , pp. 267-282
    • Novak, R.F.1    Woodcroft, K.J.2
  • 42
    • 0033939186 scopus 로고    scopus 로고
    • Endocrine disruptors and human health-is there a problem? An update
    • Safe, S.H. 2001. Endocrine disruptors and human health-is there a problem? An update. Environmental Health Perspectives 108:487-493.
    • (2001) Environmental Health Perspectives , vol.108 , pp. 487-493
    • Safe, S.H.1
  • 43
    • 0034918037 scopus 로고    scopus 로고
    • Effects of developmental exposure to diethylstilbestrol (DES) in rodents: Clues for other environmental estrogens
    • Newbold, R.R. 2001. Effects of developmental exposure to diethylstilbestrol (DES) in rodents: Clues for other environmental estrogens. APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica 109:S261-S271.
    • (2001) APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica , vol.109 , pp. S261-S271
    • Newbold, R.R.1
  • 45
    • 0035002848 scopus 로고    scopus 로고
    • Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: Evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man
    • Williams, K., C. McKinnell, P.T.K. Saunders, M. Walker, J.S. Fisher, K.J. Turner et al. 2001. Neonatal exposure to potent and environmental oestrogens and abnormalities of the male reproductive system in the rat: Evidence for importance of the androgen-oestrogen balance and assessment of the relevance to man. Human Reproduction Update 7:236-247.
    • (2001) Human Reproduction Update , vol.7 , pp. 236-247
    • Williams, K.1    McKinnell, C.2    Saunders, P.T.K.3    Walker, M.4    Fisher, J.S.5    Turner, K.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.