T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein

PLoS Pathogens

Volumn 13, Issue 7, 2017, Pages

  Fisher, Camilla R ^a   Sutton, Henry J ^b   Kaczmarski, Joe A ^a   McNamara, Hayley A ^b   Clifton, Ben ^a   Mitchell, Joshua ^a   Cai, Yeping ^b   Dups, Johanna N ^b   D'Arcy, Nicholas J ^b   Singh, Mandeep ^b   Chuah, Aaron ^b   Peat, Thomas S ^c   Jackson, Colin J ^a   Cockburn, Ian A ^b  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b Australian National University   (Australia)

^c CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CIRCUMSPOROZOITE PROTEIN; NEUTRALIZING ANTIBODY; CIRCUMSPOROZOITE PROTEIN, PROTOZOAN; MALARIA VACCINE; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DOCKING; MOUSE; NONHUMAN; PLASMODIUM; PROTEIN INTERACTION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SOMATIC HYPERMUTATION; STRUCTURAL PROTEOMICS; X RAY CRYSTALLOGRAPHY; ANIMAL; ANTIBODY AFFINITY; BAGG ALBINO MOUSE; C57BL MOUSE; CHEMISTRY; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; MALE; PLASMODIUM FALCIPARUM; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIBODY AFFINITY; B-LYMPHOCYTES; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; MALARIA VACCINES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; T-LYMPHOCYTES;

EID: 85026888674     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006469     Document Type: Article

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