-
1
-
-
84976548411
-
Old-school chemotherapy in immunotherapeutic combination in cancer, a low-cost drug repurposed
-
27196429
-
Abu Eid R, Razavi GSE, Mkrtichyan M, Janik J, Khleif SN. Old-school chemotherapy in immunotherapeutic combination in cancer, a low-cost drug repurposed. Cancer Immunol Res 2016; 4:377-82; PMID:27196429; https://doi.org/10.1158/2326-6066.CIR-16-0048
-
(2016)
Cancer Immunol Res
, vol.4
, pp. 377-382
-
-
Abu Eid, R.1
Razavi, G.S.E.2
Mkrtichyan, M.3
Janik, J.4
Khleif, S.N.5
-
2
-
-
38549148416
-
Gemcitabine has significant immunomodulatory activity in murine tumor models independent of its cytotoxic effects
-
17582217
-
Suzuki E, Sun J, Kapoor V, Jassar AS, Albelda SM. Gemcitabine has significant immunomodulatory activity in murine tumor models independent of its cytotoxic effects. Cancer Biol Ther 2007; 6:880-5; PMID:17582217; https://doi.org/10.4161/cbt.6.6.4090
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 880-885
-
-
Suzuki, E.1
Sun, J.2
Kapoor, V.3
Jassar, A.S.4
Albelda, S.M.5
-
3
-
-
73949092850
-
Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
-
19917869
-
Denkert C, Loibl S, Noske A, Roller M, Muller BM, Komor M, Budczies J, Darb-Esfahani S, Kronenwett R, Hanusch C, et al. Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer. J Clin Oncol 2010; 28:105-13; PMID:19917869; https://doi.org/10.1200/JCO.2009.23.7370
-
(2010)
J Clin Oncol
, vol.28
, pp. 105-113
-
-
Denkert, C.1
Loibl, S.2
Noske, A.3
Roller, M.4
Muller, B.M.5
Komor, M.6
Budczies, J.7
Darb-Esfahani, S.8
Kronenwett, R.9
Hanusch, C.10
-
4
-
-
80052206084
-
Prognostic and predictive impact of intra- and peritumoral immune infiltrates
-
21846822
-
Fridman WH, Galon J, Pagès F, Tartour E, Sautès-Fridman C, Kroemer G. Prognostic and predictive impact of intra- and peritumoral immune infiltrates. Cancer Res 2011; 71:5601-5; PMID:21846822; https://doi.org/10.1158/0008-5472.CAN-11-1316
-
(2011)
Cancer Res
, vol.71
, pp. 5601-5605
-
-
Fridman, W.H.1
Galon, J.2
Pagès, F.3
Tartour, E.4
Sautès-Fridman, C.5
Kroemer, G.6
-
5
-
-
84956607773
-
Immunological effects of conventional chemotherapy and targeted anticancer agents
-
26678337
-
Galluzzi L, Buqué A, Kepp O, Zitvogel L, Kroemer G. Immunological effects of conventional chemotherapy and targeted anticancer agents. Cancer Cell 2015; 28:690-714; PMID:26678337; https://doi.org/10.1016/j.ccell.2015.10.012
-
(2015)
Cancer Cell
, vol.28
, pp. 690-714
-
-
Galluzzi, L.1
Buqué, A.2
Kepp, O.3
Zitvogel, L.4
Kroemer, G.5
-
6
-
-
84969590540
-
The interplay of immunotherapy and chemotherapy, a novel approach
-
27137692
-
Hanoteau A, Henin C, Moser M. The interplay of immunotherapy and chemotherapy, a novel approach. Méd Sci M/S 2016; 32:353-61; PMID:27137692; https://doi.org/10.1051/medsci/20163204013
-
(2016)
Méd Sci M/S
, vol.32
, pp. 353-361
-
-
Hanoteau, A.1
Henin, C.2
Moser, M.3
-
7
-
-
0037022573
-
Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments
-
11880642
-
Ge Q, Hu H, Eisen HN, Chen J. Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments. PNAS 2002; 99:2989-94; PMID:11880642; https://doi.org/10.1073/pnas.052714099
-
(2002)
PNAS
, vol.99
, pp. 2989-2994
-
-
Ge, Q.1
Hu, H.2
Eisen, H.N.3
Chen, J.4
-
8
-
-
25844484607
-
+ T cells
-
16203864
-
+ T cells. J Exp Med 2005; 202:907-12; PMID:16203864; https://doi.org/10.1084/jem.20050732
-
(2005)
J Exp Med
, vol.202
, pp. 907-912
-
-
Gattinoni, L.1
Finkelstein, S.E.2
Klebanoff, C.A.3
Antony, P.A.4
Palmer, D.C.5
Spiess, P.J.6
Hwang, L.N.7
Yu, Z.8
Wrzesinski, C.9
Heimann, D.M.10
-
9
-
-
0034698931
-
Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
-
10952725
-
Goldrath AW, Bogatzki LY, Bevan MJ. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J Exp Med 2000; 192:557-64; PMID:10952725; https://doi.org/10.1084/jem.192.4.557
-
(2000)
J Exp Med
, vol.192
, pp. 557-564
-
-
Goldrath, A.W.1
Bogatzki, L.Y.2
Bevan, M.J.3
-
10
-
-
0033559510
-
Identification of a second major tumor-specific antigen recognized by CTLs on mouse mastocytoma P815
-
10092811
-
Bilsborough J, Van Pel A, Uyttenhove C, Boon T, Van den Eynde BJ. Identification of a second major tumor-specific antigen recognized by CTLs on mouse mastocytoma P815. J Immunol 1999; 162:3534-40; PMID:10092811; http://www.jimmunol.org/content/162/6/3534
-
(1999)
J Immunol
, vol.162
, pp. 3534-3540
-
-
Bilsborough, J.1
Van Pel, A.2
Uyttenhove, C.3
Boon, T.4
Van den Eynde, B.J.5
-
11
-
-
84897987185
-
+ T cells
-
24249003
-
+ T cells. Int J Cancer 2014; 134:2841-52; PMID:24249003; https://doi.org/10.1002/ijc.28617
-
(2014)
Int J Cancer
, vol.134
, pp. 2841-2852
-
-
Rahir, G.1
Wathelet, N.2
Hanoteau, A.3
Henin, C.4
Oldenhove, G.5
Galuppo, A.6
Lanaya, H.7
Colau, D.8
Mackay, C.R.9
Van den Eynde, B.10
-
12
-
-
41149099559
-
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
-
18316415
-
Sarkar S, Kalia V, Haining WN, Konieczny BT, Subramaniam S, Ahmed R. Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J Exp Med 2008; 205:625-40; PMID:18316415; https://doi.org/10.1084/jem.20071641
-
(2008)
J Exp Med
, vol.205
, pp. 625-640
-
-
Sarkar, S.1
Kalia, V.2
Haining, W.N.3
Konieczny, B.T.4
Subramaniam, S.5
Ahmed, R.6
-
14
-
-
84954349779
-
Consensus nomenclature for CD8(+) T cell phenotypes in cancer
-
26137416
-
Apetoh L, Smyth MJ, Drake CG, Abastado J-P, Apte RN, Ayyoub M, Blay J-Y, Bonneville M, Butterfield LH, Caignard A, et al. Consensus nomenclature for CD8(+) T cell phenotypes in cancer. Oncoimmunology 2015; 4:e998538; PMID:26137416; https://doi.org/10.1080/2162402X.2014.998538
-
(2015)
Oncoimmunology
, vol.4
, pp. e998538
-
-
Apetoh, L.1
Smyth, M.J.2
Drake, C.G.3
Abastado, J.-P.4
Apte, R.N.5
Ayyoub, M.6
Blay, J.-Y.7
Bonneville, M.8
Butterfield, L.H.9
Caignard, A.10
-
15
-
-
60549090859
-
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs
-
19139168
-
Cruz-Guilloty F, Pipkin ME, Djuretic IM, Levanon D, Lotem J, Lichtenheld MG, Groner Y, Rao A. Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J Exp Med 2009; 206:51-9; PMID:19139168; https://doi.org/10.1084/jem.20081242
-
(2009)
J Exp Med
, vol.206
, pp. 51-59
-
-
Cruz-Guilloty, F.1
Pipkin, M.E.2
Djuretic, I.M.3
Levanon, D.4
Lotem, J.5
Lichtenheld, M.G.6
Groner, Y.7
Rao, A.8
-
16
-
-
33847137354
-
In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor
-
17261634
-
Boissonnas A, Fetler L, Zeelenberg IS, Hugues S, Amigorena S. In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor. J Exp Med 2007; 204:345-56; PMID:17261634; https://doi.org/10.1084/jem.20061890
-
(2007)
J Exp Med
, vol.204
, pp. 345-356
-
-
Boissonnas, A.1
Fetler, L.2
Zeelenberg, I.S.3
Hugues, S.4
Amigorena, S.5
-
17
-
-
79551523389
-
Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis
-
21156650
-
Schiavoni G, Sistigu A, Valentini M, Mattei F, Sestili P, Spadaro F, Sanchez M, Lorenzi S, D'Urso MT, Belardelli F, et al. Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis. Cancer Res 2011; 71:768-78; PMID:21156650; https://doi.org/10.1158/0008-5472.CAN-10-2788
-
(2011)
Cancer Res
, vol.71
, pp. 768-778
-
-
Schiavoni, G.1
Sistigu, A.2
Valentini, M.3
Mattei, F.4
Sestili, P.5
Spadaro, F.6
Sanchez, M.7
Lorenzi, S.8
D'Urso, M.T.9
Belardelli, F.10
-
18
-
-
84953308149
-
T cell help amplifies innate signals in CD8(+) DCs for optimal CD8(+) T cell priming
-
26774484
-
Greyer M, Whitney PG, Stock AT, Davey GM, Tebartz C, Bachem A, Mintern JD, Strugnell RA, Turner SJ, Gebhardt T, et al. T cell help amplifies innate signals in CD8(+) DCs for optimal CD8(+) T cell priming. Cell Rep 2016; 14:586-97; PMID:26774484; https://doi.org/10.1016/j.celrep.2015.12.058
-
(2016)
Cell Rep
, vol.14
, pp. 586-597
-
-
Greyer, M.1
Whitney, P.G.2
Stock, A.T.3
Davey, G.M.4
Tebartz, C.5
Bachem, A.6
Mintern, J.D.7
Strugnell, R.A.8
Turner, S.J.9
Gebhardt, T.10
-
19
-
-
84933277745
-
Type I interferons in anticancer immunity
-
26027717
-
Zitvogel L, Galluzzi L, Kepp O, Smyth MJ, Kroemer G. Type I interferons in anticancer immunity. Nat Rev Immunol 2015; 15:405-14; PMID:26027717; https://doi.org/10.1038/nri3845
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 405-414
-
-
Zitvogel, L.1
Galluzzi, L.2
Kepp, O.3
Smyth, M.J.4
Kroemer, G.5
-
20
-
-
84879562239
-
+ T cells in the memory population mediate potent protective immunity
-
23746652
-
+ T cells in the memory population mediate potent protective immunity. Immunity 2013; 38:1250-60; PMID:23746652; https://doi.org/10.1016/j.immuni.2013.05.009
-
(2013)
Immunity
, vol.38
, pp. 1250-1260
-
-
Olson, J.A.1
McDonald-Hyman, C.2
Jameson, S.C.3
Hamilton, S.E.4
-
21
-
-
84990828267
-
Continuous effector CD8(+) T cell production in a controlled persistent infection is sustained by a proliferative intermediate population
-
27421704
-
Chu HH, Chan S-W, Gosling JP, Blanchard N, Tsitsiklis A, Lythe G, Shastri N, Molina-París C, Robey EA. Continuous effector CD8(+) T cell production in a controlled persistent infection is sustained by a proliferative intermediate population. Immunity 2016; 45:159-71; PMID:27421704; https://doi.org/10.1016/j.immuni.2016.06.013
-
(2016)
Immunity
, vol.45
, pp. 159-171
-
-
Chu, H.H.1
Chan, S.-W.2
Gosling, J.P.3
Blanchard, N.4
Tsitsiklis, A.5
Lythe, G.6
Shastri, N.7
Molina-París, C.8
Robey, E.A.9
-
22
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
19423728
-
Ahmadzadeh M, Johnson LA, Heemskerk B, Wunderlich JR, Dudley ME, White DE, Rosenberg SA. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 2009; 114:1537-44; PMID:19423728; https://doi.org/10.1182/blood-2008-12-195792
-
(2009)
Blood
, vol.114
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
Johnson, L.A.2
Heemskerk, B.3
Wunderlich, J.R.4
Dudley, M.E.5
White, D.E.6
Rosenberg, S.A.7
-
23
-
-
84948430497
-
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells
-
26034050
-
Odorizzi PM, Pauken KE, Paley Ma, Sharpe A, Wherry EJ. Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells. J Exp Med 2015; 212:1125-37; PMID:26034050; https://doi.org/10.1084/jem.20142237
-
(2015)
J Exp Med
, vol.212
, pp. 1125-1137
-
-
Odorizzi, P.M.1
Pauken, K.E.2
Paley, M.3
Sharpe, A.4
Wherry, E.J.5
-
24
-
-
34047163529
-
KLRG1 binds cadherins and preferentially associates with SHIP-1
-
17307799
-
Tessmer MS, Fugere C, Stevenaert F, Naidenko OV, Chong HJ, Leclercq G, Brossay L. KLRG1 binds cadherins and preferentially associates with SHIP-1. Int Immunol 2007; 19:391-400; PMID:17307799; https://doi.org/10.1093/intimm/dxm004
-
(2007)
Int Immunol
, vol.19
, pp. 391-400
-
-
Tessmer, M.S.1
Fugere, C.2
Stevenaert, F.3
Naidenko, O.V.4
Chong, H.J.5
Leclercq, G.6
Brossay, L.7
-
25
-
-
69249238113
-
KLRG-1 signalling induced proliferative dysfunction and defective Aktser473 phosphorylation in highly differentiated human CD8+ T cells
-
19406987
-
Henson S, Franzese O, Macaulay R, Libri V, Azevedo R, Kiani-Alikhan S, Plunkett F, Masters J, Jackson S, Griffiths S, et al. KLRG-1 signalling induced proliferative dysfunction and defective Aktser473 phosphorylation in highly differentiated human CD8+ T cells. Blood 2009; 113:1-3; PMID:19406987; https://doi.org/10.1182/blood-2009-01-199588
-
(2009)
Blood
, vol.113
, pp. 1-3
-
-
Henson, S.1
Franzese, O.2
Macaulay, R.3
Libri, V.4
Azevedo, R.5
Kiani-Alikhan, S.6
Plunkett, F.7
Masters, J.8
Jackson, S.9
Griffiths, S.10
-
26
-
-
84954545506
-
Situational aldehyde dehydrogenase expression by regulatory T cells may explain the contextual duality of cyclophosphamide as both a pro-inflammatory and tolerogenic agent
-
25949893
-
Kanakry CG, Ganguly S, Luznik L. Situational aldehyde dehydrogenase expression by regulatory T cells may explain the contextual duality of cyclophosphamide as both a pro-inflammatory and tolerogenic agent. Oncoimmunology 2015; 4:e974393; PMID:25949893; https://doi.org/10.4161/2162402X.2014.974393
-
(2015)
Oncoimmunology
, vol.4
, pp. e974393
-
-
Kanakry, C.G.1
Ganguly, S.2
Luznik, L.3
-
27
-
-
0034653477
-
Cyclophosphamide induces type I interferon and augments the number of CD44 hi T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer
-
10706870
-
Schiavoni G, Mattei F, Di Pucchio T, Santini SM, Bracci L, Proietti E, Belardelli F. Cyclophosphamide induces type I interferon and augments the number of CD44 hi T lymphocytes in mice:implications for strategies of chemoimmunotherapy of cancer. Blood 2000; 95:2024-30; PMID:10706870; http://www.bloodjournal.org/content/95/6/2024
-
(2000)
Blood
, vol.95
, pp. 2024-2030
-
-
Schiavoni, G.1
Mattei, F.2
Di Pucchio, T.3
Santini, S.M.4
Bracci, L.5
Proietti, E.6
Belardelli, F.7
-
28
-
-
84978419964
-
The host STING pathway at the interface of cancer and immunity
-
27367184
-
Corrales L, McWhirter SM, Dubensky TW, Gajewski TF. The host STING pathway at the interface of cancer and immunity. J Clin Invest 2016; 126:2404-11; PMID:27367184; https://doi.org/10.1172/JCI86892
-
(2016)
J Clin Invest
, vol.126
, pp. 2404-2411
-
-
Corrales, L.1
McWhirter, S.M.2
Dubensky, T.W.3
Gajewski, T.F.4
-
29
-
-
66149156276
-
Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment
-
19293190
-
Harlin H, Meng Y, Peterson AC, Zha Y, Tretiakova M, Slingluff C, McKee M, Gajewski TF. Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment. Cancer Res 2009; 69:3077-85; PMID:19293190; https://doi.org/10.1158/0008-5472.CAN-08-2281
-
(2009)
Cancer Res
, vol.69
, pp. 3077-3085
-
-
Harlin, H.1
Meng, Y.2
Peterson, A.C.3
Zha, Y.4
Tretiakova, M.5
Slingluff, C.6
McKee, M.7
Gajewski, T.F.8
-
30
-
-
80355136945
-
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells
-
21930765
-
Fuertes MB, Kacha AK, Kline J, Woo S-R, Kranz DM, Murphy KM, Gajewski TF. Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells. J Exp Med 2011; 208:2005-16; PMID:21930765; https://doi.org/10.1084/jem.20101159
-
(2011)
J Exp Med
, vol.208
, pp. 2005-2016
-
-
Fuertes, M.B.1
Kacha, A.K.2
Kline, J.3
Woo, S.-R.4
Kranz, D.M.5
Murphy, K.M.6
Gajewski, T.F.7
-
31
-
-
67649220219
-
IFN-a enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activity
-
19494262
-
Sikora AG, Jaffarzad N, Hailemichael Y, Gelbard A, Stonier SW, Schluns KS, Frasca L, Lou Y, Liu C, Andersson HA, et al. IFN-a enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activity. J Immunol 2009; 182:7398-407; PMID:19494262; https://doi.org/10.4049/jimmunol.0802982
-
(2009)
J Immunol
, vol.182
, pp. 7398-7407
-
-
Sikora, A.G.1
Jaffarzad, N.2
Hailemichael, Y.3
Gelbard, A.4
Stonier, S.W.5
Schluns, K.S.6
Frasca, L.7
Lou, Y.8
Liu, C.9
Andersson, H.A.10
-
32
-
-
84978499806
-
Chemotherapy and immunotherapy: a close interplay to fight cancer?
-
27622046
-
Hanoteau A, Moser M. Chemotherapy and immunotherapy:a close interplay to fight cancer? Oncoimmunology 2016; 5:e1190061; PMID:27622046; https://doi.org/10.1080/2162402X.2016.1190061
-
(2016)
Oncoimmunology
, vol.5
, pp. e1190061
-
-
Hanoteau, A.1
Moser, M.2
-
33
-
-
84959152038
-
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients
-
26901407
-
Gros A, Parkhurst MR, Tran E, Pasetto A, Robbins PF, Ilyas S, Prickett TD, Gartner JJ, Crystal JS, Roberts IM, et al. Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients. Nat Med 2016; 22:433-8; PMID:26901407; https://doi.org/10.1038/nm.4051
-
(2016)
Nat Med
, vol.22
, pp. 433-438
-
-
Gros, A.1
Parkhurst, M.R.2
Tran, E.3
Pasetto, A.4
Robbins, P.F.5
Ilyas, S.6
Prickett, T.D.7
Gartner, J.J.8
Crystal, J.S.9
Roberts, I.M.10
-
34
-
-
84928761118
-
Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
25765070
-
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, Lee W, Yuan J, Wong P, Ho TS, et al. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 2015; 348:124-8; PMID:25765070; https://doi.org/10.1126/science.aaa1348
-
(2015)
Science
, vol.348
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
Kvistborg, P.4
Makarov, V.5
Havel, J.J.6
Lee, W.7
Yuan, J.8
Wong, P.9
Ho, T.S.10
-
35
-
-
84994364943
-
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
-
27789795
-
Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen D, Kurachi M, et al. Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade. Science 2016; 2807:1-10; PMID:27789795; https://doi.org/10.1126/science.aaf2807
-
(2016)
Science
, vol.2807
, pp. 1-10
-
-
Pauken, K.E.1
Sammons, M.A.2
Odorizzi, P.M.3
Manne, S.4
Godec, J.5
Khan, O.6
Drake, A.M.7
Chen, Z.8
Sen, D.9
Kurachi, M.10
|