메뉴 건너뛰기




Volumn 94, Issue , 2017, Pages 197-205

Navel orange peel hydroethanolic extract, naringin and naringenin have anti-diabetic potentials in type 2 diabetic rats

Author keywords

NA STZ diabetes model; Narengenin; Naringin; Navel orange

Indexed keywords

ADIPONECTIN; ANTIDIABETIC AGENT; ANTIOXIDANT; AURANTIIN; C PEPTIDE; CHOLESTEROL; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSE TRANSPORTER 4; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; NARINGENIN; NAVEL ORANGE PEEL HYDROETHANOLIC EXTRACT; NICOTINAMIDE; PLANT EXTRACT; STREPTOZOCIN; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; ALCOHOL; FLAVANONE DERIVATIVE; WATER;

EID: 85026428806     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.07.094     Document Type: Article
Times cited : (116)

References (72)
  • 1
    • 84944453438 scopus 로고    scopus 로고
    • In vivo and in vitro antidiabetic effects of citrus flavonoids; a study on the mechanism of action
    • Mahmoud, A.M., Ahmed, O.M., Ashour, M.B., Abdel-Moneim, A., In vivo and in vitro antidiabetic effects of citrus flavonoids; a study on the mechanism of action. Int. J. Diabetes Dev. Ctries. 35:3 (2015), 250–263.
    • (2015) Int. J. Diabetes Dev. Ctries. , vol.35 , Issue.3 , pp. 250-263
    • Mahmoud, A.M.1    Ahmed, O.M.2    Ashour, M.B.3    Abdel-Moneim, A.4
  • 2
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: estimates for theyear 2000 and projections for 2030
    • Wild, S., Roglic, G., Green, A., Sicree, R., King, H., Global prevalence of diabetes: estimates for theyear 2000 and projections for 2030. Diabetes Care 27:5 (2004), 1047–1053.
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 3
    • 28844503938 scopus 로고    scopus 로고
    • Prevalence, predisposition and prevention of type II diabetes
    • Cheng, D., Prevalence, predisposition and prevention of type II diabetes. Nutr. Metab. (Lond.), 2, 2005, 29.
    • (2005) Nutr. Metab. (Lond.) , vol.2 , pp. 29
    • Cheng, D.1
  • 4
    • 84860845827 scopus 로고    scopus 로고
    • The use of animal models in diabetes research
    • King, A.J.F., The use of animal models in diabetes research. Br. J. Pharmacol. 166:3 (2012), 877–894.
    • (2012) Br. J. Pharmacol. , vol.166 , Issue.3 , pp. 877-894
    • King, A.J.F.1
  • 5
    • 75149130955 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association, Diagnosis and classification of diabetes mellitus. Diabetes Care 33:1 (2010), S62–S69.
    • (2010) Diabetes Care , vol.33 , Issue.1 , pp. S62-S69
    • American Diabetes Association1
  • 6
    • 84914164473 scopus 로고    scopus 로고
    • Streptozotocin-nicotinamide-induced rat model of type 2 diabetes (review)
    • Ghasemi, A., Khalifi, S., Jedi, S., Streptozotocin-nicotinamide-induced rat model of type 2 diabetes (review). Acta Physiol. Hung. 101:4 (2014), 408–420.
    • (2014) Acta Physiol. Hung. , vol.101 , Issue.4 , pp. 408-420
    • Ghasemi, A.1    Khalifi, S.2    Jedi, S.3
  • 7
    • 0036898999 scopus 로고    scopus 로고
    • Genotoxicity of streptozotocin
    • Bolzán, A.D., Bianchi, M.S., Genotoxicity of streptozotocin. Mutat. Res. 512 (2002), 121–134.
    • (2002) Mutat. Res. , vol.512 , pp. 121-134
    • Bolzán, A.D.1    Bianchi, M.S.2
  • 8
    • 12244297093 scopus 로고    scopus 로고
    • Protective effect of epicatechin against the toxic effects of STZ on rat pancreatic islets: in vivo and in vitro
    • Kim, M.J., Ryu, G.R., Chung, J.S., Sim, S.S., Min, D.S., Rhie, D.J., Protective effect of epicatechin against the toxic effects of STZ on rat pancreatic islets: in vivo and in vitro. Pancreas 26 (2003), 292–299.
    • (2003) Pancreas , vol.26 , pp. 292-299
    • Kim, M.J.1    Ryu, G.R.2    Chung, J.S.3    Sim, S.S.4    Min, D.S.5    Rhie, D.J.6
  • 9
    • 33744737240 scopus 로고    scopus 로고
    • Antidiabetic activity of fruits of Terminalia chebula on streptozotocin induced diabetic rats
    • Kumar, G.P.S., Arulselvan, P., Kumar, D.S., Subramanian, S.P., Antidiabetic activity of fruits of Terminalia chebula on streptozotocin induced diabetic rats. J. Health Sci. 52 (2006), 283–291.
    • (2006) J. Health Sci. , vol.52 , pp. 283-291
    • Kumar, G.P.S.1    Arulselvan, P.2    Kumar, D.S.3    Subramanian, S.P.4
  • 10
    • 0027739947 scopus 로고
    • Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets
    • Turk, J., Corbett, J.A., Ramanadham, S., Bohrer, A., McDaniel, M.L., Biochemical evidence for nitric oxide formation from streptozotocin in isolated pancreatic islets. Biochem. Biophys. Res. Commun. 197 (1993), 1458–1464.
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 1458-1464
    • Turk, J.1    Corbett, J.A.2    Ramanadham, S.3    Bohrer, A.4    McDaniel, M.L.5
  • 11
    • 84908504693 scopus 로고    scopus 로고
    • Review of the mechanism of cell death resulting from streptozotocin challenge in experimental animals, its practical use and potential risk to humans
    • Eleazu, C.O., Eleazu, K.C., Chukwuma, S., Essien, U.N., Review of the mechanism of cell death resulting from streptozotocin challenge in experimental animals, its practical use and potential risk to humans. J. Diabetes Metab. Disord. 12:60 (2013), 1–7.
    • (2013) J. Diabetes Metab. Disord. , vol.12 , Issue.60 , pp. 1-7
    • Eleazu, C.O.1    Eleazu, K.C.2    Chukwuma, S.3    Essien, U.N.4
  • 12
    • 44949237971 scopus 로고    scopus 로고
    • Adiponectin and its association with insulin resistance and type 2 diabetes
    • Sheng, T., Yang, K., Adiponectin and its association with insulin resistance and type 2 diabetes. J. Genet. Genomics 35:6 (2008), 321–326.
    • (2008) J. Genet. Genomics , vol.35 , Issue.6 , pp. 321-326
    • Sheng, T.1    Yang, K.2
  • 13
    • 85026346155 scopus 로고    scopus 로고
    • Adiponectin signaling and function in insulin target tissues
    • Ruan, H., Dong, L.Q., Adiponectin signaling and function in insulin target tissues. J. Mol. Cell Biol. 2016 (2016), 1–35.
    • (2016) J. Mol. Cell Biol. , vol.2016 , pp. 1-35
    • Ruan, H.1    Dong, L.Q.2
  • 15
    • 85026383311 scopus 로고    scopus 로고
    • Citrus Peel Benefits
    • The American University of Washington, DC
    • Fraley, A., Citrus Peel Benefits. 2010, The American University of Washington, DC.
    • (2010)
    • Fraley, A.1
  • 16
    • 85026373928 scopus 로고    scopus 로고
    • Natural Bioactive Compounds of Citrus Lemon for Food and Health
    • Elsevier B.V., USA
    • Gonzalez-Molina, E., Dominguez-Peries, R., Moreno, C., Garcia-Viguera, C., Natural Bioactive Compounds of Citrus Lemon for Food and Health. 2009, Elsevier, B.V., USA.
    • (2009)
    • Gonzalez-Molina, E.1    Dominguez-Peries, R.2    Moreno, C.3    Garcia-Viguera, C.4
  • 17
    • 0034852659 scopus 로고    scopus 로고
    • Phenols in citrus peel by-products. Concentrations of hy droxy cinnamates and poly methoxylated flavones in citrus peel molasses
    • Manthey, A., Grohmann, K., Phenols in citrus peel by-products. Concentrations of hy droxy cinnamates and poly methoxylated flavones in citrus peel molasses. J. Agric. Food Chem. 49:7 (2001), 3268–3273.
    • (2001) J. Agric. Food Chem. , vol.49 , Issue.7 , pp. 3268-3273
    • Manthey, A.1    Grohmann, K.2
  • 18
    • 77449129288 scopus 로고    scopus 로고
    • Patterns of carotenoid pigments extracted from two orange peel wastes (Valencia and Navel var.)
    • Chedea, V.S., Kefalas, P., Socacin, C., Patterns of carotenoid pigments extracted from two orange peel wastes (Valencia and Navel var.). J. Food Biochem. 34:9 (2010), 101–110.
    • (2010) J. Food Biochem. , vol.34 , Issue.9 , pp. 101-110
    • Chedea, V.S.1    Kefalas, P.2    Socacin, C.3
  • 19
    • 32644449264 scopus 로고    scopus 로고
    • Chemical composition and bioactive compounds of flour of orange (Citrus sinensis), tangerine (Citrus reticulate) and grapefruit (Citrus paradisl) peels cultivated in Venezuela
    • Rincon, A.M., Vasquez, A.M., Padilla, F.C., Chemical composition and bioactive compounds of flour of orange (Citrus sinensis), tangerine (Citrus reticulate) and grapefruit (Citrus paradisl) peels cultivated in Venezuela. Arch. Latinoam Nutr. 55:3 (2005), 305–310.
    • (2005) Arch. Latinoam Nutr. , vol.55 , Issue.3 , pp. 305-310
    • Rincon, A.M.1    Vasquez, A.M.2    Padilla, F.C.3
  • 20
    • 70449127048 scopus 로고    scopus 로고
    • Poly methoxy flavones are responsible for the antiflammatory activity of citrus fruit peel
    • Huang, Y.S., Ho, S.C., Poly methoxy flavones are responsible for the antiflammatory activity of citrus fruit peel. Food Chem. 119:3 (2010), 868–873.
    • (2010) Food Chem. , vol.119 , Issue.3 , pp. 868-873
    • Huang, Y.S.1    Ho, S.C.2
  • 21
    • 33746894472 scopus 로고    scopus 로고
    • Differences in the carotenoid content of ordinary citrus and lycopene-accumulating mutants
    • Xu, C.J., Fraser, P.D., Wang, W.J., Bramley, P.M., Differences in the carotenoid content of ordinary citrus and lycopene-accumulating mutants. J. Agric. Food Chem. 54:12 (2006), 5472–5481.
    • (2006) J. Agric. Food Chem. , vol.54 , Issue.12 , pp. 5472-5481
    • Xu, C.J.1    Fraser, P.D.2    Wang, W.J.3    Bramley, P.M.4
  • 23
    • 54249141439 scopus 로고    scopus 로고
    • Anti-diabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation
    • Ortiz, R.R., Sanchez, S.J.C., Navarrete, V.G., Webster, S.P., Binnie, M., Garcia, J.S., Anti-diabetic and toxicological evaluations of naringenin in normoglycaemic and NIDDM rat models and its implications on extra-pancreatic glucose regulation. Diab. Obes. Metab. 10 (2008), 1097–1104.
    • (2008) Diab. Obes. Metab. , vol.10 , pp. 1097-1104
    • Ortiz, R.R.1    Sanchez, S.J.C.2    Navarrete, V.G.3    Webster, S.P.4    Binnie, M.5    Garcia, J.S.6
  • 24
    • 85026370161 scopus 로고    scopus 로고
    • Evaluation of antihyperglycemic activity of citrus peels powders fortified biscuits in albino induced diabetic rats
    • Youssef, M.K.E., Youssef, H.M., Mousa, R.M., Evaluation of antihyperglycemic activity of citrus peels powders fortified biscuits in albino induced diabetic rats. Food Public Health 3:3 (2013), 161–167.
    • (2013) Food Public Health , vol.3 , Issue.3 , pp. 161-167
    • Youssef, M.K.E.1    Youssef, H.M.2    Mousa, R.M.3
  • 25
    • 77951229157 scopus 로고    scopus 로고
    • antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens and rutin in nicotinamide/streptozotocin diabetic albino rats
    • Ahmed, O.M., Abdel-Moneim, A., Abulyazid, I., Antihyperglycemic, Mahmoud A.M., antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens and rutin in nicotinamide/streptozotocin diabetic albino rats. Diabetol. Croat. 39 (2010), 15–32.
    • (2010) Diabetol. Croat. , vol.39 , pp. 15-32
    • Ahmed, O.M.1    Abdel-Moneim, A.2    Abulyazid, I.3    Antihyperglycemic, M.A.M.4
  • 27
    • 84896923700 scopus 로고    scopus 로고
    • Antihyperglycemic effects of water extract of Ulva lactuca and its polysaccharides in nicotinamide-streptozotocin-induced diabetic rats, Egypt
    • Ahmed, O.M., Antihyperglycemic effects of water extract of Ulva lactuca and its polysaccharides in nicotinamide-streptozotocin-induced diabetic rats, Egypt. J. Zool. 54 (2010), 273–297.
    • (2010) J. Zool. , vol.54 , pp. 273-297
    • Ahmed, O.M.1
  • 28
    • 84896925738 scopus 로고    scopus 로고
    • Anti-hyperlipidemic, antioxidant and cardiac improving effects of water extract of Ulva lactuca and its polysaccharides in nicotinamide-streptozotocin-induced diabetic rats, Egypt
    • Ahmed, O.M., Anti-hyperlipidemic, antioxidant and cardiac improving effects of water extract of Ulva lactuca and its polysaccharides in nicotinamide-streptozotocin-induced diabetic rats, Egypt. J. Zool. 54 (2010), 253–272.
    • (2010) J. Zool. , vol.54 , pp. 253-272
    • Ahmed, O.M.1
  • 29
    • 0003072603 scopus 로고
    • Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor
    • Trinder, P., Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann. Clin. Biochem. 6 (1969), 24–27.
    • (1969) Ann. Clin. Biochem. , vol.6 , pp. 24-27
    • Trinder, P.1
  • 30
    • 12144266466 scopus 로고
    • The estimation of glycogen with anthrone reagent
    • Seifter, S., Dayton, S., Novic, B., Muntwyler, E., The estimation of glycogen with anthrone reagent. Arch. Biochem. 25 (1950), 191–200.
    • (1950) Arch. Biochem. , vol.25 , pp. 191-200
    • Seifter, S.1    Dayton, S.2    Novic, B.3    Muntwyler, E.4
  • 31
    • 0018223876 scopus 로고
    • Serum enzymes in human and experimental diabetes mellitus
    • Begum, N., Sam, G.P., Shanmugasundaram, K.R., Serum enzymes in human and experimental diabetes mellitus. Indian J. Med. Res. 68 (1978), 774–784.
    • (1978) Indian J. Med. Res. , vol.68 , pp. 774-784
    • Begum, N.1    Sam, G.P.2    Shanmugasundaram, K.R.3
  • 32
    • 0016795414 scopus 로고
    • The stimulation of liver phosphorylase b by AMP, fluoride and sulphate. A technical note on the specific determination of the a and b forms of liver glycogen phophorylase
    • Stalmans, W., Hers, H., The stimulation of liver phosphorylase b by AMP, fluoride and sulphate. A technical note on the specific determination of the a and b forms of liver glycogen phophorylase. Eur. J. Biochem. 54:2 (1975), 341–350.
    • (1975) Eur. J. Biochem. , vol.54 , Issue.2 , pp. 341-350
    • Stalmans, W.1    Hers, H.2
  • 33
    • 0003974503 scopus 로고
    • Clinical Guide to Laboratory Tests
    • 2nd edition W.B. Saunders Co. Philadelphia, PA
    • Tietz, N.W., Clinical Guide to Laboratory Tests. 2nd edition, 1990, W.B. Saunders Co., Philadelphia, PA.
    • (1990)
    • Tietz, N.W.1
  • 34
    • 0016373654 scopus 로고
    • Enzymatic determination of total serum cholesterol
    • Allain, C.C., Poon, L.S., Chan, C.S., Richmond, W., Fu, P.C., Enzymatic determination of total serum cholesterol. Clin. Chem. 20:4 (1974), 470–475.
    • (1974) Clin. Chem. , vol.20 , Issue.4 , pp. 470-475
    • Allain, C.C.1    Poon, L.S.2    Chan, C.S.3    Richmond, W.4    Fu, P.C.5
  • 35
    • 0015348189 scopus 로고
    • Estimation of concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge
    • Friedewald, W.T., Estimation of concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin. Chem. 18:7 (1972), 499–502.
    • (1972) Clin. Chem. , vol.18 , Issue.7 , pp. 499-502
    • Friedewald, W.T.1
  • 36
    • 0003974503 scopus 로고
    • Clinical Guide to Laboratory Tests
    • 3rd edition Philadelphia PA: W.B. Saunders Co
    • Nobert, W.T., Clinical Guide to Laboratory Tests. 3rd edition, 1995, Philadelphia, PA: W.B. Saunders Co.
    • (1995)
    • Nobert, W.T.1
  • 37
    • 0001558285 scopus 로고
    • The colorimetric microdetermination of non-esterified fatty acids in plasma
    • Duncombe, W.G., The colorimetric microdetermination of non-esterified fatty acids in plasma. Clin. Chim. Acta 9 (1961), 122–125.
    • (1961) Clin. Chim. Acta , vol.9 , pp. 122-125
    • Duncombe, W.G.1
  • 38
    • 0031948697 scopus 로고    scopus 로고
    • Comparative effects of chromium, vanadium and Gymnema sylvestre on sugar inducedblood pressure elevations in SHR
    • Preuss, H.G., Jarrel, S.T., Scheckenbach, R., Lieberman, S., Anderson, R.A., Comparative effects of chromium, vanadium and Gymnema sylvestre on sugar inducedblood pressure elevations in SHR. J. Am. Coll. Nutr. 17:2 (1998), 116–123.
    • (1998) J. Am. Coll. Nutr. , vol.17 , Issue.2 , pp. 116-123
    • Preuss, H.G.1    Jarrel, S.T.2    Scheckenbach, R.3    Lieberman, S.4    Anderson, R.A.5
  • 39
    • 73649194769 scopus 로고
    • Improved method for determination of blood glutathione
    • Beutler, E., Duron, O., Kelly, B.M., Improved method for determination of blood glutathione. J. Lab. Clin. Med. 61 (1963), 882–888.
    • (1963) J. Lab. Clin. Med. , vol.61 , pp. 882-888
    • Beutler, E.1    Duron, O.2    Kelly, B.M.3
  • 40
    • 0031887415 scopus 로고    scopus 로고
    • Oxidative stress in experimental diabetes induced by streptozotocin
    • Matkovics, B., Kotorman, M., Varga, I.S., Hai, D.Q., Vrga, C., Oxidative stress in experimental diabetes induced by streptozotocin. Acta Physiol. Hung. 85:1 (1997), 29–38.
    • (1997) Acta Physiol. Hung. , vol.85 , Issue.1 , pp. 29-38
    • Matkovics, B.1    Kotorman, M.2    Varga, I.S.3    Hai, D.Q.4    Vrga, C.5
  • 41
    • 0019763615 scopus 로고
    • Glutathione transferase (human placenta)
    • Mannervik, B., Gutenberg, C., Glutathione transferase (human placenta). Methods Enzymol. 77 (1981), 231–235.
    • (1981) Methods Enzymol. , vol.77 , pp. 231-235
    • Mannervik, B.1    Gutenberg, C.2
  • 42
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanatephenol chloroform extraction
    • Chomzynski, P., Sacchi, N., Single step method of RNA isolation by acid guanidinium thiocyanatephenol chloroform extraction. Annu. Rev. Biochem. 162 (1987), 156–159.
    • (1987) Annu. Rev. Biochem. , vol.162 , pp. 156-159
    • Chomzynski, P.1    Sacchi, N.2
  • 43
    • 0025089978 scopus 로고
    • P.M. Wertheim-van Dillen, J. van der Noordaa, Rapid and simple method for purification of nucleic acids
    • Boom, R., Sol, C.J., Salimans, M.M., Jansen, C.L., P.M. Wertheim-van Dillen, J. van der Noordaa, Rapid and simple method for purification of nucleic acids. J. Clin. Microbiol. 28:3 (1990), 495–503.
    • (1990) J. Clin. Microbiol. , vol.28 , Issue.3 , pp. 495-503
    • Boom, R.1    Sol, C.J.2    Salimans, M.M.3    Jansen, C.L.4
  • 44
    • 0003903343 scopus 로고    scopus 로고
    • Molecular Cloning Laboratory Manual
    • 5th ed. Chemical Industry Press Beijing
    • Sambrook, J., Russell, D.W., Molecular Cloning Laboratory Manual. 5th ed., 2008, Chemical Industry Press, Beijing.
    • (2008)
    • Sambrook, J.1    Russell, D.W.2
  • 45
    • 58549085809 scopus 로고    scopus 로고
    • Chronic ethanol consumption resulting in the downregulation of insulin receptor-beta subunit, insulin receptor substrate-1, and glucose transporter 4 expression in rat cardiac muscles
    • Limin, T., Hou, X., Liu, J., Zhang, X., Sun, N., Gao, L., Zhao, J., Chronic ethanol consumption resulting in the downregulation of insulin receptor-beta subunit, insulin receptor substrate-1, and glucose transporter 4 expression in rat cardiac muscles. Alcohol 43:1 (2009), 51–58.
    • (2009) Alcohol , vol.43 , Issue.1 , pp. 51-58
    • Limin, T.1    Hou, X.2    Liu, J.3    Zhang, X.4    Sun, N.5    Gao, L.6    Zhao, J.7
  • 48
    • 84871749061 scopus 로고    scopus 로고
    • Vaspin gene in rat adipose tissue: relation to obesity-induced insulin resistance
    • Shaker, O.G., Sadik, N.A., Vaspin gene in rat adipose tissue: relation to obesity-induced insulin resistance. Mol. Cell Biochem. 373 (2013), 229–239.
    • (2013) Mol. Cell Biochem. , vol.373 , pp. 229-239
    • Shaker, O.G.1    Sadik, N.A.2
  • 49
    • 85017140386 scopus 로고
    • One Way Analysis, Version 1A(C), PC-STAT
    • University of Georgia Athens, USA
    • Roa, M., Blane, K., Zonneberg, M., One Way Analysis, Version 1A(C), PC-STAT. 1985, University of Georgia, Athens, USA.
    • (1985)
    • Roa, M.1    Blane, K.2    Zonneberg, M.3
  • 50
    • 84862006013 scopus 로고    scopus 로고
    • Streptozotocin-nicotinamide-induced diabetes in the rat. Characteristics of the experimental model
    • Szkudelski, T., Streptozotocin-nicotinamide-induced diabetes in the rat. Characteristics of the experimental model. Exp. Biol. Med. (Maywood) 237 (2012), 481–490.
    • (2012) Exp. Biol. Med. (Maywood) , vol.237 , pp. 481-490
    • Szkudelski, T.1
  • 51
    • 84900362297 scopus 로고    scopus 로고
    • Antihyperglycemic: hypolipidemic and antioxidant activities of total saponins extracted from Aralia taibaiensis in experimental type 2 diabetic rats
    • Weng, Y., Yu, L., Cui, J., Zhu, R.Z., Guo, C., Wei, G., et al. Antihyperglycemic: hypolipidemic and antioxidant activities of total saponins extracted from Aralia taibaiensis in experimental type 2 diabetic rats. J. Ethnopharmacol. 152 (2014), 553–560.
    • (2014) J. Ethnopharmacol. , vol.152 , pp. 553-560
    • Weng, Y.1    Yu, L.2    Cui, J.3    Zhu, R.Z.4    Guo, C.5    Wei, G.6
  • 52
    • 65249171452 scopus 로고    scopus 로고
    • Westernized-like-diet-fed rats: effect on glucose homeostasis, lipid profile, and adipocyte hormones and their modulation by rosiglitazone and glimepiride
    • Schaalan, M., El-Abhar, H.S., Barakat, M., El-Denshary, E.S., Westernized-like-diet-fed rats: effect on glucose homeostasis, lipid profile, and adipocyte hormones and their modulation by rosiglitazone and glimepiride. J. Diabetes Complicat. 23 (2009), 199–208.
    • (2009) J. Diabetes Complicat. , vol.23 , pp. 199-208
    • Schaalan, M.1    El-Abhar, H.S.2    Barakat, M.3    El-Denshary, E.S.4
  • 53
    • 84867612534 scopus 로고    scopus 로고
    • Antidiabetic effects of hesperdin and naringin in type 2 diabetic rats
    • Ahmed, O.M., Mahmoud, A.M., Abdel-Moneim, A., Ashour, M.B., Antidiabetic effects of hesperdin and naringin in type 2 diabetic rats. Diabetol. Croat. 41:2 (2012), 53–67.
    • (2012) Diabetol. Croat. , vol.41 , Issue.2 , pp. 53-67
    • Ahmed, O.M.1    Mahmoud, A.M.2    Abdel-Moneim, A.3    Ashour, M.B.4
  • 54
    • 0037089037 scopus 로고    scopus 로고
    • Insulin resistance: organ manifestations and cellular mechanisms
    • Beck-Nielsen, H., Insulin resistance: organ manifestations and cellular mechanisms. Ugeskr. Laeger 164 (2002), 2130–2135.
    • (2002) Ugeskr. Laeger , vol.164 , pp. 2130-2135
    • Beck-Nielsen, H.1
  • 55
    • 0014961401 scopus 로고
    • The effect of diabetes and insulin on liver glycogen synthetase activation
    • Gold, A.H., The effect of diabetes and insulin on liver glycogen synthetase activation. J. Biol. Chem. 245 (1970), 903–905.
    • (1970) J. Biol. Chem. , vol.245 , pp. 903-905
    • Gold, A.H.1
  • 56
    • 0003146514 scopus 로고    scopus 로고
    • Diabetes mellitus
    • D.L. Kasper A.S. Fauci D.L. Longo E. Braunwald S.L. Hauser J.L. Jameson 16th ed. McGraw-Hill Co. Inc. 2005
    • Powers, A.C., Diabetes mellitus. Kasper, D.L., Fauci, A.S., Longo, D.L., Braunwald, E., Hauser, S.L., Jameson, J.L., (eds.) Harrison's Principles of Internal Medicine, 16th ed., 2017, McGraw-Hill Co. Inc., 2005.
    • (2017) Harrison's Principles of Internal Medicine
    • Powers, A.C.1
  • 58
    • 0037452139 scopus 로고    scopus 로고
    • Adiponectin and protection against type 2 diabetes mellitus
    • Spranger, J., Kroke, A., Mohlig, M., et al. Adiponectin and protection against type 2 diabetes mellitus. Lancet 361 (2003), 226–228.
    • (2003) Lancet , vol.361 , pp. 226-228
    • Spranger, J.1    Kroke, A.2    Mohlig, M.3
  • 59
    • 0028997729 scopus 로고
    • The beta-cell in diabetes: from molecular genetics to clinical research
    • Polonsky, K.S., The beta-cell in diabetes: from molecular genetics to clinical research. Diabetes 44:6 (1995), 705–717.
    • (1995) Diabetes , vol.44 , Issue.6 , pp. 705-717
    • Polonsky, K.S.1
  • 61
    • 0036206555 scopus 로고    scopus 로고
    • Attenuating CV risk factors in patient with diabetes: clinical evidence to clinical practice
    • Garber, A.J., Attenuating CV risk factors in patient with diabetes: clinical evidence to clinical practice. Diabetes Obes. Metab. 4:Suppl. (1) (2002), S5–12.
    • (2002) Diabetes Obes. Metab. , vol.4 , pp. S5-12
    • Garber, A.J.1
  • 62
    • 27644562695 scopus 로고    scopus 로고
    • Antihyperlipidemic and antiperoxidative effect of Diasulin, a polyherbal formulation in alloxan induced hyperglycemic rats
    • Saravanan, R., Pari, L., Antihyperlipidemic and antiperoxidative effect of Diasulin, a polyherbal formulation in alloxan induced hyperglycemic rats. BMC Complement Altern. Med. 22 (2005), 14–21.
    • (2005) BMC Complement Altern. Med. , vol.22 , pp. 14-21
    • Saravanan, R.1    Pari, L.2
  • 63
    • 85016143779 scopus 로고    scopus 로고
    • Role of antioxidant in oxidative stress and diabetes mellitus
    • Khan, A.N., Khan, R.A., Ahmad, M., Mushtaq, N., Role of antioxidant in oxidative stress and diabetes mellitus. J. Pharmacogn. Phytochem. 3:6 (2015), 217–220.
    • (2015) J. Pharmacogn. Phytochem. , vol.3 , Issue.6 , pp. 217-220
    • Khan, A.N.1    Khan, R.A.2    Ahmad, M.3    Mushtaq, N.4
  • 64
    • 33645241629 scopus 로고    scopus 로고
    • Chronic administration of Satsuma mandarin fruit improves oxidative stress in streptozotocin induced diabetic rat liver
    • Sugiura, M., Ohshima, M., Ogawa, K., Yano, M., Chronic administration of Satsuma mandarin fruit improves oxidative stress in streptozotocin induced diabetic rat liver. Biol. Pharmacol. Bull. 29 (2006), 588–591.
    • (2006) Biol. Pharmacol. Bull. , vol.29 , pp. 588-591
    • Sugiura, M.1    Ohshima, M.2    Ogawa, K.3    Yano, M.4
  • 65
    • 84895888771 scopus 로고    scopus 로고
    • O-hexadecyl-dextran entrapped berberine nanoparticles abrogate high glucose stress induced apoptosis in primary rat hepatocytes
    • Singh, K.S., Tripathi, M., Bhatnagar, P., Kakkar, P., Gupta, K.C., O-hexadecyl-dextran entrapped berberine nanoparticles abrogate high glucose stress induced apoptosis in primary rat hepatocytes. PLoS One, 9(2), 2014, e89124.
    • (2014) PLoS One , vol.9 , Issue.2 , pp. e89124
    • Singh, K.S.1    Tripathi, M.2    Bhatnagar, P.3    Kakkar, P.4    Gupta, K.C.5
  • 66
    • 84884562299 scopus 로고    scopus 로고
    • Hemeoxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy
    • Zhao, Y., Zhang, L., Qiao, Y., Zhou, X., Wu, G., Hemeoxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy. PLoS One, 8(9), 2013, e75927.
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e75927
    • Zhao, Y.1    Zhang, L.2    Qiao, Y.3    Zhou, X.4    Wu, G.5
  • 67
    • 6344249036 scopus 로고    scopus 로고
    • The influence of naringin on the oxidative state of rats with streptozotocin-induced acute hyperglycaemia
    • Ali, M.M., Abd El-Kader, M.A., The influence of naringin on the oxidative state of rats with streptozotocin-induced acute hyperglycaemia. Zeitschriftfur Naturforschung Section C 59:9–10 (2004), 726–733.
    • (2004) Zeitschriftfur Naturforschung Section C , vol.59 , Issue.9-10 , pp. 726-733
    • Ali, M.M.1    Abd El-Kader, M.A.2
  • 68
    • 0004250729 scopus 로고    scopus 로고
    • Harper’ Biochemistry
    • 25th ed. Appleton and Lange Stanford, CT
    • Murray, R.K., Granner, D.K., Mayes, P.A., Rodwell, V.W., Harper’ Biochemistry. 25th ed., 2000, Appleton and Lange, Stanford, CT.
    • (2000)
    • Murray, R.K.1    Granner, D.K.2    Mayes, P.A.3    Rodwell, V.W.4
  • 69
    • 84922722787 scopus 로고    scopus 로고
    • Naringenin accords hepatoprotection from streptozotocin induced diabetes in vivo by modulating mitochondrial dysfunction and apoptotic signaling cascade
    • Kapoor, R., Kakkar, P., Naringenin accords hepatoprotection from streptozotocin induced diabetes in vivo by modulating mitochondrial dysfunction and apoptotic signaling cascade. Toxicol. Rep. 1 (2014), 569–581.
    • (2014) Toxicol. Rep. , vol.1 , pp. 569-581
    • Kapoor, R.1    Kakkar, P.2
  • 70
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi, T., Kamon, J., Waki, H., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7 (2001), 941–946.
    • (2001) Nat. Med. , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 71
    • 13444270891 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived hepatic insulin sensitizer regulation during development
    • Kim, J.Y., Scherer, P.E., Adiponectin, an adipocyte-derived hepatic insulin sensitizer regulation during development. Pediatr. Endocrinol. Rev. 1:Suppl (3) (2004), 428–431.
    • (2004) Pediatr. Endocrinol. Rev. , vol.1 , pp. 428-431
    • Kim, J.Y.1    Scherer, P.E.2
  • 72
    • 0032211979 scopus 로고    scopus 로고
    • Searching for ways to upregulate GLUT4 glucose transporter expression in muscle
    • Zorzano, A., Santalucia, A., Palacín, M., Guma, A., Camps, M., Searching for ways to upregulate GLUT4 glucose transporter expression in muscle. Gen. Pharmacol. 31 (1998), 705–713.
    • (1998) Gen. Pharmacol. , vol.31 , pp. 705-713
    • Zorzano, A.1    Santalucia, A.2    Palacín, M.3    Guma, A.4    Camps, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.