Anticancer activity and therapeutic applications of chitosan nanoparticles

Chitin, Chitosan, Oligosaccharides and Their Derivatives: Biological Activities and Applications

Volumn , Issue , 2010, Pages 271-282

  Ta, Hang T ^a   Dunstan, Dave E ^a   Dass, Crispin R ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ST VINCENT S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85026258432     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/EBK1439816035     Document Type: Chapter

References (58)

1. Bae, K. H., Ha, Y. J., Kim, C., Lee, K.-R., and Park, T. G. 2008. Pluronic/chitosan shell crosslinked nanocapsules encapsulating magnetic nanoparticles. J. Biomater. Sci., Polym. Ed, 19: 1571-1583.
2. Berrada, M., Serreqi, A., Dabbarh, F., Owusu, A., Gupta, A., and Lehnert, S. 2005. A novel non-toxic camptothecin formulation for cancer chemotherapy. Biomaterials, 26: 2115-2120.
3. Carreno-Gomez, B. and Duncan, A. 1997. Evaluation of the biological properties of soluble chitosan and chitosan microspheres. Int. J. Pharm., 148: 231-240.
4. Chan, D. C. F., Kirpotin, D. B., and Bunn, P. A. J. 1997. Scientific and Clinical Applications of Magnetic Carriers, Plenum, New York.
5. Chandy, T. and Sharma, C. P. 1990. Chitosan as a biomaterial. Biomater. Artif. Cells Artif. Organs, 18: 1-24.
6. Chen, W. R., Adams, R. L., Carubelli, R., and Nordquist, R. E. 1997. Laser-photosensitizer assisted immunotherapy: A novel modality for cancer treatment. Cancer Lett., 115: 25-30.
7. Chihara, G., Maeda, Y., Hamuro, J., Sasaki, T., and Fukuoka, F. 1969. Inhibition of mouse sarcoma 180 by polysaccharides from Lentinus edodes (Berk.) sing. Nature, 222: 687-688.
8. Dash, A. K., Gong, Z., Miler, D. W., Huai-Yan, H., and Laforet, J. 1990. Development of a rectal nicotine delivery system for the treatment of ulcerative colitis. Int. J. Pharm., 190: 21-34.
9. Dougherty, T. J., Gomer, C. J., Henderson, B. W. et al. 1998. Photodynamic therapy. J. Natl. Cancer Inst., 90: 889-905.
10. Fiebrig, I., Harding, S. E., Rowe, A. J., Hyman, S. C., and Davis, S. S. 1995. Transmission electron microscopy on pig gastric mucin and its interaction with chitosan. Carbohydr. Polym., 28: 239-244.
11. Fukumori, Y. and Ichikawa, H. 2006. Nanoparticles for cancer therapy and diagnosis. Adv. Powder Technol., 17: 1-28.
12. Ganguly, S. and Dash, A. K. 2004. A novel in situ gel for sustained drug delivery and targeting. Int. J. Pharm., 276: 83-92.
13. Guminska, M., Ignacak, J., and Wojcik, E. 1996. In vitro inhibitory effect of chitosan and its degradation products on energy metabolism in Ehrlich ascites tumour cells (EAT). Pol. J. Pharmacol., 48: 495-501.
14. Han, H. D., Song, C. K., Park, Y. S. et al. 2007. A chitosan hydrogel-based cancer drug delivery system exhibits synergistic antitumor effects by combining with a vaccinia viral vaccine. Int. J. Pharm., 350: 27-34.
15. Hasegawa, M., Yagi, K., Iwakawa, S., and Hirai, M. 2001. Chitosan induces apoptosis via caspase-3 activation in bladder tumour cells. Jpn. J. Cancer Res., 4: 459-466.
16. He, P., Davis, S. S., and Illum, L. 1998. In vitro evaluation of the mucoadhesive properties of chitosan microspheres. Int. J. Pharm., 166: 75-88.
17. Henriksen, I., Green, K. L., and Smart, J. D. 1996. Bioadhesion of hydrated chitosans: An in vitro study. Int. J. Pharm., 145: 231-240.
18. Hirano, S., Yamaguchi, R., and Fukui, N. 1990. A chitosan oxalate gel: Its conversion to an N-acetylchitosan gel via a chitosan gel. Carbohydr. Res., 201: 145-149.
19. Jauhari, S. and Dash, A. K. 2006. A mucoadhesive in situ gel delivery system for paclitaxel. AAPS PharmSciTech, 7: Article 53: E1-E6. http://www.aapspharmscitech.org/view.asp?art=pt070253
20. Kim, D.-H., Kim, K.-N., Kim, K.-M., and Lee, Y.-K. 2009. Targeting to carcinoma cells with chitosanand starch-coated magnetic nanoparticles for magnetic hyperthermia. J. Biomed. Mater. Res. Part A, 88: 1-11.
21. Kodama, N., Harada, N., and Nanba, H. 2002. A polysaccharide, extract from Grifola frondaosa, induces Th-1 dominant responses in carcinoma-bearing BALB/c mice. Jpn. J. Pharmacol., 90: 357-360.
22. Kumar, M. N. V. R. 2000. A review of chitin and chitosan applications. React. Funct. Polym., 46: 1-27.
23. Larsson, K. 1989. Cubic lipid-water phases. Structures and biomembrane aspects. J. Phys. Chem., 93: 7304-7314.
24. Lee, S.-J., Kim, S. W., Chung, H. et al. 2005. Bioadhesive drug delivery system using glyceryl monooleate for the intravesical administration of paclitaxel. Chemotherapy, 51: 311-318.
25. Lin-Gibson, S., Walls, H. J., Kennedy, S. B., and Welsh, E. R. 2003. Chitosan hydrogels: Crosslink kinetics and gel properties. Polym. Mater. Sci. Eng., 88: 199-200.
26. Lu, Z. R., Ye, F., and Vaidya, A. 2007. Polymer platforms for drug delivery and biomedical imaging. J. Control. Release, 122: 269-277.
27. Martini, A. and Lauria, S. 2003. Sustained release injectable products. Am. Pharm. Rev., 6: 16-20.
28. Masashige, S. 2002. Functional magnetic particles for medical application. J. Biosci. Bioeng., 94: 606-613.
29. Mitraa, S., Gaura, U., Ghosha, P. C., and Maitra, A. N. 2001. Tumour targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier. J. Control. Release, 74: 317-323.
30. Murata, J., Saiki, I., Makabe, T., Tsuta, Y., Tokura, S., and Azuma, I. 1991. Inhibition of tumor-induced angiogenesis by sulfated chitin derivative. Cancer Res., 51: 22-26.
31. Murata, J., Saiki, I., Nishimura, S., Nishi, N., Tokura, S., and Azuma, I. 1989. Inhibitory effect of chitin heparinoids on the lung metastasis of B16-B16 melanoma. Jpn. J. Cancer Res., 80: 866-872.
32. Muzzarelli, R. A. A. 1993. Biochemical significance of exogenous chitins and chitosans in animals and patients. Carbohydr. Polym., 20: 7-16.
33. Nam, K.-S. and Shon, Y.-H. 2008. Suppression of metastasis of human breast cancer cells by chitosan oligosaccharides. J. Microbiol. Biotechnol., doi: 10.4014/jmb.0811.603.
34. Nam, H. Y., Kwon, S. M., Chung, H. et al. 2009. Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J. Control. Release, 135: 259-267.
35. Nielsen, L. S., Schubert, L., and Hansen, J. 1998. Bioadhesive drug delivery systems I. Characterization of mucoadhesive properties of systems based on glyceryl mono-oleate and glyceryl monolinooleate. Eur. J. Pharm. Sci., 6: 231-239.
36. Nishimura, K., Nishimura, S., Nishi, N., Saiki, I., Tokura, S., and Azuma, I. 1984. Immunological activity of chitin and its derivatives. Vaccine, 2: 93-98.
37. Obara, K., Ishiharab, M., Ozekia, Y. et al. 2005. Controlled release of paclitaxel from photocrosslinked chitosan hydrogels and its subsequent effect on subcutaneous tumor growth in mice. J. Control. Release, 110: 79-89.
38. Ono, K., Ishihara, M., Ishikawa, K. et al. 2002. Non-anticoagulant heparin carrying polystyrene (NAC-HCPS) affects angiogenesis and inhibits subcutaneous induced tumor growth and metastasis to the lung. Br. J. Cancer, 86: 1803-1812.
39. Ono, K., Saito, Y., Yura, H., and Ishikawa, K. 2000. Photocrosslinkable chitosan as a biological adhesive. J. Biomed. Mater. Res., Part A, 49: 289-295.
40. Ruel-Gariepy, E., Chenite, A., Chaput, C., Guirguis, S., and Leroux, J. C. 2000. Characterization of thermosensitive chitosan gels for the sustained delivery of drugs. Int. J. Pharm., 203: 89-98.
41. Ruel-Gariepy, E., Shive, M., Bichara, A. et al. 2004. A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel. Eur. J. Pharm. Biopharm., 57: 53-63.
42. Sinha, V. R., Singla, A. K., Wadhawan, S. et al. 2004. Chitosan microspheres as a potential carrier for drugs. Int. J. Pharm., 274: 1-33.
43. Sun, Y., Chen, Z.-L., Yang, X.-X., Huang, P., Zhou, X.-P., and Du, X.-X. 2009. Magnetic chitosan nanoparticles as a drug delivery system for targeting photodynamic therapy. Nanotechnology, 20: 135102-135110.
44. Ta, H. T., Dass, C. R., Choong, P. F., and Dunstan, D. E. 2009a. Osteosarcoma treatment: State of the art. Cancer Metastasis Rev., 28: 247-263.
45. Ta, H. T., Dass, C. R., Larson, I., Choong, P. F. M., and Dunstan, D. E. 2009b. A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy. Biomaterials, doi:10.1016/j.biomaterials.2009.05.035.
46. Ta, H. T., Dass, C. R., Larson, I., Choong, P. F. M., and Dunstan, D. E. 2009c. A chitosan-dipotassium orthophosphate hydrogel for the delivery of Doxorubicin in the treatment of osteosarcoma. Biomaterials, 30: 3605-3613.
47. Ta, H. T., Han, H., Larson, I., Dass, C. R., and Dunstan, D. E. 2009d. Chitosan-dibasic orthophosphate hydrogel: A potential drug delivery system. Int. J. Pharm., doi:10.1016/j.ijpharm.2009.01.018.
48. Takeuchi, H., Yamamoto, H., Niwa, T., Hino, T., and Kawachima, Y. 1996. Enternal absorption of insulin in rats from mucoadhesive chitosan-coated liposomes. Pharm. Res., 13: 896-900.
49. Tan, W. B., Jiang, S., and Zhang, Y. 2007. Quantum-dot based nanoparticles for targeted silencing of HER2/neu gene via RNA interference. Biomaterials, 28: 1565-1571.
50. Tokoro, A., Tatewaki, N., Suzuki, K., Mikami, T., Suzuki, S., and Suzuki, M. 1988. Growth-inhibitory effect of hexa-N-acetylchitohexaose and chitohexaose against Meth-A solid tumor. Chem. Pharm. Bull., 36: 784-790.
51. Tokumitsu, H., Ichikawa, H., and Fukumori, Y. 1999. Chitosan-gadopentetic acid complex nanoparticles for gadolinium neutron capture therapy of cancer: Preparation by novel emulsion droplet coalescence technique and characterization. Pharm. Res., 16: 1830-1835.
52. Tsai, K.-C., Shieh, M.-J., Yang, S.-J., Lin, W.-L., and Chen, W.-S. 2008. Chitosan nanoparticle combined with ultrasound for cervical cancer detection. Paper presented at the 2008 NSTI Nanotechnology Conference and Trade Show, Boston, MA.
53. Ueno, H., Mori, T., and Fujinaga, T. 2001. Topical formulations and wound healing applications of chitosan. Adv. Drug Deliv. Rev., 52: 105-115.
54. Wang, X., Yang, L., Chen, Z. G., and Shin, D. M. 2008. Application of nanotechnology in cancer therapy and imaging. CA Cancer J. Clin., 58: 97-110.
55. WHO. 2006. Cancer. http://www.who.int/mediacentre/factsheets/fs297/en/ (access July 9, 2007).
56. Wong, H., Endayan, R., Rauth, A. M., Li, Y., and Wu, X. Y. 2007. Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles. Adv. Drug Deliv. Rev., 59: 491-504.
57. Wyatt, D. M. and Dorschel, D. 1992. A cubic-phase delivery system composed of glyceryl monooleate and water for sustained release of water-soluble drugs. Pharm. Tech., 10: 116-130.
58. Yang, S.-J., Chen, J.-W., and Shieh, M.-J. 2008. Colorectal cancer cell detection by chitosan nanoparticle conjugated with folic acid. Paper presented at the 2008 NSTI Nanotechnology Conference and Trade Show, Boston, MA.