Thymol inhibits bladder cancer cell proliferation via inducing cell cycle arrest and apoptosis

Biochemical and Biophysical Research Communications

Volumn 491, Issue 2, 2017, Pages 530-536

  Li, Yi ^a,b   Wen, Jia ming ^a   Du, Chuan jun ^a   Hu, Su min ^a   Chen, Jia xi ^a   Zhang, Shi geng ^a   Zhang, Nan ^a   Gao, Feng ^a   Li, Shao jiang ^a   Mao, Xia wa ^a   Miyamoto, Hiroshi ^b   Ding, Ke feng ^a  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Bladder cancer; MAPKs; ROS; Thymol

Indexed keywords

CASPASE 3; CASPASE 9; CYCLIN A; CYCLIN B1; CYCLIN DEPENDENT KINASE 2; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; THYMOL; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANTHRACENE DERIVATIVE; ANTINEOPLASTIC AGENT; BCL2 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN KINASE INHIBITOR; PYRAZOLANTHRONE; PYRIDINE DERIVATIVE; SCAVENGER;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BLADDER CANCER CELL LINE; CANCER INHIBITION; CELL CYCLE ARREST; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; IC50; INTRACELLULAR SIGNALING; MTT ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; TRANSFORMED CELL LINE; TUMOR CELL LINE; UROTHELIUM;

ACETYLCYSTEINE; ANTHRACENES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASE 9; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; EPITHELIAL CELLS; FREE RADICAL SCAVENGERS; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMIDAZOLES; MAP KINASE KINASE 4; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRIDINES; REACTIVE OXYGEN SPECIES; THYMOL; UROTHELIUM;

EID: 85025428516     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.04.009     Document Type: Article

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