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Volumn 6, Issue 7, 2017, Pages 1296-1304

A Glucose-Sensing Toggle Switch for Autonomous, High Productivity Genetic Control

Author keywords

genetic toggle switch; glucose sensing; metabolic engineering; PHB production

Indexed keywords

GLUCOSE; HYDROXYBUTYRIC ACID; POLYHYDROXYBUTYRATE; UNCLASSIFIED DRUG;

EID: 85025134872     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.6b00257     Document Type: Article
Times cited : (45)

References (30)
  • 1
    • 84966269203 scopus 로고    scopus 로고
    • Energy- and carbon-efficient synthesis of functionalized small molecules in bacteria using non-decarboxylative Claisen condensation reactions
    • Cheong, S., Clomburg, J. M., and Gonzalez, R. (2016) Energy- and carbon-efficient synthesis of functionalized small molecules in bacteria using non-decarboxylative Claisen condensation reactions Nat. Biotechnol. 34, 1-8 10.1038/nbt.3505
    • (2016) Nat. Biotechnol. , vol.34 , pp. 1-8
    • Cheong, S.1    Clomburg, J.M.2    Gonzalez, R.3
  • 2
    • 51049094673 scopus 로고    scopus 로고
    • High cell density media for Escherichia coli are generally designed for aerobic cultivations - Consequences for large-scale bioprocesses and shake flask cultures
    • Soini, J., Ukkonen, K., and Neubauer, P. (2008) High cell density media for Escherichia coli are generally designed for aerobic cultivations-consequences for large-scale bioprocesses and shake flask cultures Microb. Cell Fact. 7, 26 10.1186/1475-2859-7-26
    • (2008) Microb. Cell Fact. , vol.7 , pp. 26
    • Soini, J.1    Ukkonen, K.2    Neubauer, P.3
  • 3
    • 85028550972 scopus 로고    scopus 로고
    • Synthetic and systems biology for microbial production of commodity chemicals: From target selection to scale-up
    • Chubukov, V., Mukhopadhyay, A., Petzold, C. J., Keasling, J. D., and García Martín, H. (2016) Synthetic and systems biology for microbial production of commodity chemicals: from target selection to scale-up NPJ Syst. Biol. Appl. 2, 16009 10.1038/npjsba.2016.9
    • (2016) NPJ Syst. Biol. Appl. , vol.2 , pp. 16009
    • Chubukov, V.1    Mukhopadhyay, A.2    Petzold, C.J.3    Keasling, J.D.4    García Martín, H.5
  • 4
    • 68449103617 scopus 로고    scopus 로고
    • Stabilized gene duplication enables long-term selection-free heterologous pathway expression
    • Tyo, K. E. J., Ajikumar, P. K., and Stephanopoulos, G. (2009) Stabilized gene duplication enables long-term selection-free heterologous pathway expression Nat. Biotechnol. 27, 760-767 10.1038/nbt.1555
    • (2009) Nat. Biotechnol. , vol.27 , pp. 760-767
    • Tyo, K.E.J.1    Ajikumar, P.K.2    Stephanopoulos, G.3
  • 5
    • 84898613992 scopus 로고    scopus 로고
    • Environmental dependence of stationary-phase metabolism in Bacillus subtilis and Escherichia coli
    • Chubukov, V. and Sauer, U. (2014) Environmental dependence of stationary-phase metabolism in Bacillus subtilis and Escherichia coli Appl. Environ. Microbiol. 80, 2901-9 10.1128/AEM.00061-14
    • (2014) Appl. Environ. Microbiol. , vol.80 , pp. 2901-2909
    • Chubukov, V.1    Sauer, U.2
  • 6
    • 14244270260 scopus 로고    scopus 로고
    • Analysis of Gene Expression in Escherichia coli in Response to Changes of Growth-Limiting Nutrient in Chemostat Cultures
    • Hua, Q., Yang, C., Oshima, T., Mori, H., and Shimizu, K. (2004) Analysis of Gene Expression in Escherichia coli in Response to Changes of Growth-Limiting Nutrient in Chemostat Cultures Appl. Environ. Microbiol. 70, 2354-2366 10.1128/AEM.70.4.2354-2366.2004
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 2354-2366
    • Hua, Q.1    Yang, C.2    Oshima, T.3    Mori, H.4    Shimizu, K.5
  • 7
    • 79251538647 scopus 로고    scopus 로고
    • Transcriptional regulation of main metabolic pathways of cyoA, cydB, fnr, and fur gene knockout Escherichia coli in C-limited and N-limited aerobic continuous cultures
    • Kumar, R. and Shimizu, K. (2011) Transcriptional regulation of main metabolic pathways of cyoA, cydB, fnr, and fur gene knockout Escherichia coli in C-limited and N-limited aerobic continuous cultures Microb. Cell Fact. 10, 3 10.1186/1475-2859-10-3
    • (2011) Microb. Cell Fact. , vol.10 , pp. 3
    • Kumar, R.1    Shimizu, K.2
  • 8
    • 0034688174 scopus 로고    scopus 로고
    • Construction of a genetic toggle switch in Escherichia coli
    • Gardner, T. S., Cantor, C. R., and Collins, J. J. (2000) Construction of a genetic toggle switch in Escherichia coli Nature 403, 339-342 10.1038/35002131
    • (2000) Nature , vol.403 , pp. 339-342
    • Gardner, T.S.1    Cantor, C.R.2    Collins, J.J.3
  • 9
    • 84869078490 scopus 로고    scopus 로고
    • Iterative plug-and- play methodology for constructing and modifying synthetic gene networks
    • Litcofsky, K. D., Afeyan, R. B., Krom, R. J., Khalil, A. S., and Collins, J. J. (2012) Iterative plug-and- play methodology for constructing and modifying synthetic gene networks Nat. Methods 9, 1077-1081 10.1038/nmeth.2205
    • (2012) Nat. Methods , vol.9 , pp. 1077-1081
    • Litcofsky, K.D.1    Afeyan, R.B.2    Krom, R.J.3    Khalil, A.S.4    Collins, J.J.5
  • 10
    • 84899628032 scopus 로고    scopus 로고
    • Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch
    • Soma, Y., Tsuruno, K., Wada, M., Yokota, A., and Hanai, T. (2014) Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch Metab. Eng. 23, 175-184 10.1016/j.ymben.2014.02.008
    • (2014) Metab. Eng. , vol.23 , pp. 175-184
    • Soma, Y.1    Tsuruno, K.2    Wada, M.3    Yokota, A.4    Hanai, T.5
  • 11
    • 84928753819 scopus 로고    scopus 로고
    • Self-induced metabolic state switching by a tunable cell density sensor for microbial isopropanol production
    • Soma, Y. and Hanai, T. (2015) Self-induced metabolic state switching by a tunable cell density sensor for microbial isopropanol production Metab. Eng. 30, 7-15 10.1016/j.ymben.2015.04.005
    • (2015) Metab. Eng. , vol.30 , pp. 7-15
    • Soma, Y.1    Hanai, T.2
  • 13
    • 84904720029 scopus 로고    scopus 로고
    • Regulation Systems of Bacteria such as Escherichia coli in Response to Nutrient Limitation and Environmental Stresses
    • Shimizu, K. (2014) Regulation Systems of Bacteria such as Escherichia coli in Response to Nutrient Limitation and Environmental Stresses Metabolites 4, 1-35 10.3390/metabo4010001
    • (2014) Metabolites , vol.4 , pp. 1-35
    • Shimizu, K.1
  • 14
    • 0035811172 scopus 로고    scopus 로고
    • Determination of the maximum specific uptake capacities for glucose and oxygen in glucose-limited fed-batch cultivations of Escherichia coli
    • Lin, H. Y., Mathiszik, B., Xu, B., Enfors, S., and Neubauer, P. (2001) Determination of the maximum specific uptake capacities for glucose and oxygen in glucose-limited fed-batch cultivations of Escherichia coli Biotechnol. Bioeng. 73, 347 10.1002/bit.1068
    • (2001) Biotechnol. Bioeng. , vol.73 , pp. 347
    • Lin, H.Y.1    Mathiszik, B.2    Xu, B.3    Enfors, S.4    Neubauer, P.5
  • 15
    • 79957788648 scopus 로고    scopus 로고
    • Novel Roles of cAMP Receptor Protein (CRP) in Regulation of Transport and Metabolism of Carbon Sources
    • Shimada, T., Fujita, N., Yamamoto, K., and Ishihama, A. (2011) Novel Roles of cAMP Receptor Protein (CRP) in Regulation of Transport and Metabolism of Carbon Sources PLoS One 6, e20081 10.1371/journal.pone.0020081
    • (2011) PLoS One , vol.6 , pp. e20081
    • Shimada, T.1    Fujita, N.2    Yamamoto, K.3    Ishihama, A.4
  • 16
    • 0032698634 scopus 로고    scopus 로고
    • Transcription Activation by Catabolite Activator Protein (CAP)
    • Busby, S. and Ebright, R. H. (1999) Transcription Activation by Catabolite Activator Protein (CAP) J. Mol. Biol. 293, 199-213 10.1006/jmbi.1999.3161
    • (1999) J. Mol. Biol. , vol.293 , pp. 199-213
    • Busby, S.1    Ebright, R.H.2
  • 17
    • 0032526956 scopus 로고    scopus 로고
    • Transcription activation at Class II CRP-dependent promoters: Identification of determinants in the C-terminal domain of the RNA polymerase α subunit
    • Savery, N. J., Lloyd, G. S., Kainz, M., Gaal, T., Ross, W., Ebright, R. H., Gourse, R. L., and Busby, S. J. W. (1998) Transcription activation at Class II CRP-dependent promoters: identification of determinants in the C-terminal domain of the RNA polymerase α subunit EMBO J. 17, 3439-3447 10.1093/emboj/17.12.3439
    • (1998) EMBO J. , vol.17 , pp. 3439-3447
    • Savery, N.J.1    Lloyd, G.S.2    Kainz, M.3    Gaal, T.4    Ross, W.5    Ebright, R.H.6    Gourse, R.L.7    Busby, S.J.W.8
  • 18
    • 77950858901 scopus 로고    scopus 로고
    • Analysis of polyhydroxybutyrate flux limitations by systematic genetic and metabolic perturbations
    • Tyo, K. E. J., Fischer, C. R., Simeon, F., and Stephanopoulos, G. (2010) Analysis of polyhydroxybutyrate flux limitations by systematic genetic and metabolic perturbations Metab. Eng. 12, 187-195 10.1016/j.ymben.2009.10.005
    • (2010) Metab. Eng. , vol.12 , pp. 187-195
    • Tyo, K.E.J.1    Fischer, C.R.2    Simeon, F.3    Stephanopoulos, G.4
  • 20
    • 0032519978 scopus 로고    scopus 로고
    • Spacing Requirements for interactions between the C-terminal domain of α subunit of Escherichia coli RNA polymerase and the cAMP receptor protein
    • Lloyd, G. S., Busby, S. J. W., and Savery, N. J. (1998) Spacing Requirements for interactions between the C-terminal domain of α subunit of Escherichia coli RNA polymerase and the cAMP receptor protein Biochem. J. 420, 413-420 10.1042/bj3300413
    • (1998) Biochem. J. , vol.420 , pp. 413-420
    • Lloyd, G.S.1    Busby, S.J.W.2    Savery, N.J.3
  • 21
  • 23
    • 84922462319 scopus 로고    scopus 로고
    • Regulatory effects on central carbon metabolism from poly-3-hydroxybutryate synthesis
    • Sekar, K. and Tyo, K. E. J. (2015) Regulatory effects on central carbon metabolism from poly-3-hydroxybutryate synthesis Metab. Eng. 28, 180-9 10.1016/j.ymben.2015.01.003
    • (2015) Metab. Eng. , vol.28 , pp. 180-189
    • Sekar, K.1    Tyo, K.E.J.2
  • 24
    • 33646542650 scopus 로고    scopus 로고
    • High-Throughput Screen for Poly-3-Hydroxybutyrate in Escherichia coli and Synechocystis sp. Strain PCC6803
    • Tyo, K. E., Zhou, H., and Stephanopoulos, G. N. (2006) High-Throughput Screen for Poly-3-Hydroxybutyrate in Escherichia coli and Synechocystis sp. Strain PCC6803 Appl. Environ. Microbiol. 72, 3412-3417 10.1128/AEM.72.5.3412-3417.2006
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 3412-3417
    • Tyo, K.E.1    Zhou, H.2    Stephanopoulos, G.N.3
  • 25
    • 0030861452 scopus 로고    scopus 로고
    • Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
    • Lutz, R. and Bujard, H. (1997) Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements Nucleic Acids Res. 25, 1203-1210 10.1093/nar/25.6.1203
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1203-1210
    • Lutz, R.1    Bujard, H.2
  • 26
    • 83055177124 scopus 로고    scopus 로고
    • Tuning gene expression in Yarrowia lipolytica by a hybrid promoter approach
    • Blazeck, J., Liu, L., Redden, H., and Alper, H. (2011) Tuning gene expression in Yarrowia lipolytica by a hybrid promoter approach Appl. Environ. Microbiol. 77, 7905-7914 10.1128/AEM.05763-11
    • (2011) Appl. Environ. Microbiol. , vol.77 , pp. 7905-7914
    • Blazeck, J.1    Liu, L.2    Redden, H.3    Alper, H.4
  • 27
    • 84856586594 scopus 로고    scopus 로고
    • A strategy of gene overexpression based on tandem repetitive promoters in Escherichia coli
    • Li, M., Wang, J., Geng, Y., Li, Y., Wang, Q., Liang, Q., and Qi, Q. (2012) A strategy of gene overexpression based on tandem repetitive promoters in Escherichia coli Microb. Cell Fact. 11, 19 10.1186/1475-2859-11-19
    • (2012) Microb. Cell Fact. , vol.11 , pp. 19
    • Li, M.1    Wang, J.2    Geng, Y.3    Li, Y.4    Wang, Q.5    Liang, Q.6    Qi, Q.7
  • 28
    • 78651397316 scopus 로고    scopus 로고
    • Robust multicellular computing using genetically encoded NOR gates and chemical "wires
    • Tamsir, A., Tabor, J. J., and Voigt, C. A. (2011) Robust multicellular computing using genetically encoded NOR gates and chemical "wires Nature 469, 212-5 10.1038/nature09565
    • (2011) Nature , vol.469 , pp. 212-215
    • Tamsir, A.1    Tabor, J.J.2    Voigt, C.A.3
  • 29
    • 84867389802 scopus 로고    scopus 로고
    • RNA processing enables predictable programming of gene expression
    • Qi, L., Haurwitz, R. E., Shao, W., Doudna, J. A., and Arkin, A. P. (2012) RNA processing enables predictable programming of gene expression Nat. Biotechnol. 30, 1002-1006 10.1038/nbt.2355
    • (2012) Nat. Biotechnol. , vol.30 , pp. 1002-1006
    • Qi, L.1    Haurwitz, R.E.2    Shao, W.3    Doudna, J.A.4    Arkin, A.P.5
  • 30
    • 84948395539 scopus 로고    scopus 로고
    • The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite
    • Huergo, L. F. and Dixon, R. (2015) The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite Microbiol. Mol. Biol. Rev. 79, 419-435 10.1128/MMBR.00038-15
    • (2015) Microbiol. Mol. Biol. Rev. , vol.79 , pp. 419-435
    • Huergo, L.F.1    Dixon, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.