The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes

Cell Reports

Volumn 20, Issue 3, 2017, Pages 613-626

  Jeevan Raj, Beena ^a,c   Gehrig, Jasmine ^a,d   Charmoy, Mélanie ^a   Chennupati, Vijaykumar ^a   Grandclément, Camille ^a,e   Angelino, Paolo ^b   Delorenzi, Mauro ^b   Held, Werner ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF BASEL   (Switzerland)

^d ASTRAZENECA   (United Kingdom)

^e R and D Transcure Bioservices   (France)

Author keywords

granzyme B; NK cells; self destruction; T cell factor 1; Tcf1

Indexed keywords

GRANZYME B; TRANSCRIPTION FACTOR 7; GRANZYME; GZMB PROTEIN, MOUSE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HNF1A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW PROGENITOR CELL; CELL EXPANSION; CELL LINEAGE; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; FEMALE; LYMPHOCYTE FUNCTION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE;

ANIMALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANZYMES; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; KILLER CELLS, NATURAL; MICE; MICE, KNOCKOUT;

EID: 85025112624     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.06.071     Document Type: Article

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