Black Raspberries and Their Anthocyanin and Fiber Fractions Alter the Composition and Diversity of Gut Microbiota in F-344 Rats

Nutrition and Cancer

Volumn 69, Issue 6, 2017, Pages 943-951

  Pan, Pan ^a   Lam, Vy ^a   Salzman, Nita ^a   Huang, Yi Wen ^a   Yu, Jianhua ^b   Zhang, Jianying ^c   Wang, Li Shu ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHOCYANIN;

AKKERMANSIA; ANAEROSTIPES; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BACTERIAL COUNT; CONTROLLED STUDY; DESULFOVIBRIO; DIET; FECES ANALYSIS; FISCHER 344 RAT; GRAM POSITIVE BACTERIUM; INTESTINE FLORA; MALE; MICROBIAL COMMUNITY; NONHUMAN; PLANT FIBER; RASPBERRY; RAT; VERRUCOMICROBIA; ANALYSIS; ANIMAL; CHEMISTRY; CLOSTRIDIALES; DIETARY FIBER; DRUG EFFECT; FECES; FRUIT; ISOLATION AND PURIFICATION; MICROBIOLOGY; PHARMACOLOGY; RUBUS;

ANIMALS; ANTHOCYANINS; CLOSTRIDIALES; DESULFOVIBRIO; DIET; DIETARY FIBER; FECES; FRUIT; GASTROINTESTINAL MICROBIOME; RATS; RATS, INBRED F344; RUBUS; VERRUCOMICROBIA;

EID: 85024493672     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2017.1340491     Document Type: Article

References (49)

1. Ley RE, Peterson DA, Gordon JI, : Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 124, 837–848, 2006.
2. Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, et al.: A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464, 59–65, 2010.
3. Guinane CM, Cotter PD, : Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ. Therap Adv Gastroenterol 6, 295–308, 2013.
4. Zhang H, DiBaise JK, Zuccolo A, Kudrna D, Braidotti M, et al.: Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci U S A 106, 2365–2370, 2009.
5. Qin J, Li Y, Cai Z, Li S, Zhu J, et al.: A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490, 55–60, 2012.
6. Kau AL, Ahern PP, Griffin NW, Goodman AL, Gordon JI, : Human nutrition, the gut microbiome and the immune system. Nature 474, 327–336, 2011.
7. Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, et al.: Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 104, 13780–13785, 2007.
8. Claesson MJ, Jeffery IB, Conde S, Power SE, O'Connor EM, et al.: Gut microbiota composition correlates with diet and health in the elderly. Nature 488, 178–184, 2012.
9. O'Keefe SJ, Li JV, Lahti L, Ou J, Carbonero F, et al.: Fat, fibre and cancer risk in African Americans and rural Africans. Nat Commun 6, 6342, 2015.
10. Kresty LA, Morse MA, Morgan C, Carlton PS, Lu J, et al.: Chemoprevention of esophageal tumorigenesis by dietary administration of lyophilized black raspberries. Cancer Res 61, 6112–6119, 2001.
11. Wang LS, Hecht SS, Carmella SG, Yu N, Larue B, et al.: Anthocyanins in black raspberries prevent esophageal tumors in rats. Cancer Prev Res (Phila) 2, 84–93, 2009.
12. Voragen FGJ, Timmers JPJ, Linssen JPH, Schols HA, Pilnik W, : Methods of analysis for cell-wall polysaccharides of fruit and vegetables. Z Lebensm Unters Forsch 177, 251–256, 1983.
13. Ross HA, McDougall GJ, Stewart D, : Antiproliferative activity is predominantly associated with ellagitannins in raspberry extracts. Phytochemistry 68, 218–228, 2007.
14. Stoner GD, : Foodstuffs for preventing cancer: the preclinical and clinical development of berries. Cancer Prev Res 2, 187–194, 2009.
15. McKenna P, Hoffmann C, Minkah N, Aye PP, Lackner A, et al.: The macaque gut microbiome in health, lentiviral infection, and chronic enterocolitis. PLoS Pathog 4, e20, 2008.
16. Dethlefsen L, Huse S, Sogin ML, Relman DA, : The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol 6, e280, 2008.
17. Ohtani N, : Microbiome and cancer. Semin Immunopathol 37, 65–72, 2015.
18. Greiner AK, Papineni RV, Umar S, : Chemoprevention in gastrointestinal physiology and disease. Natural products and microbiome. Am J Physiol Gastrointest Liver Physiol 307, G1–G15, 2014.
19. Frank DN, Zhu W, Sartor RB, Li E, : Investigating the biological and clinical significance of human dysbioses. Trends Microbiol 19, 427–434, 2011.
20. Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, et al.: Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 482, 179–185, 2012.
21. Ley RE, Turnbaugh PJ, Klein S, Gordon JI, : Microbial ecology: human gut microbes associated with obesity. Nature 444, 1022–1023, 2006.
22. Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, et al.: Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 455, 1109–1113, 2008.
23. Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, et al.: Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 328, 228–231, 2010.
24. Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, et al.: Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 472, 57–63, 2011.
25. Miyoshi J, Chang EB, : The gut microbiota and inflammatory bowel diseases. Transl Res 2016.
26. Akin H, Tozun N, : Diet, microbiota, and colorectal cancer. J Clin Gastroenterol 48(Suppl 1), S67–S69, 2014.
27. Vendrame S, Guglielmetti S, Riso P, Arioli S, Klimis-Zacas D, et al.: Six-week consumption of a wild blueberry powder drink increases bifidobacteria in the human gut. J Agric Food Chem 59, 12815–12820, 2011.
28. Paturi G, Butts CA, Bentley-Hewitt KL, Ansell J, : Influence of green and gold kiwifruit on indices of large bowel function in healthy rats. J Food Sci 79, H1611–H1620, 2014.
29. Wang LS, Arnold M, Huang YW, Sardo C, Seguin C, et al.: Modulation of genetic and epigenetic biomarkers of colorectal cancer in humans by black raspberries: a phase I pilot study. Clin Cancer Res 17, 598–610, 2011.
30. Wang LS, Burke CA, Hasson H, Kuo CT, Molmenti CL, et al.: A phase Ib study of the effects of black raspberries on rectal polyps in patients with familial adenomatous polyposis. Cancer Prev Res (Phila) 7, 666–674, 2014.
31. Pan P, Skaer CW, Stirdivant SM, Young MR, Stoner GD, et al.: Beneficial regulation of metabolic profiles by black raspberries in human colorectal cancer patients. Cancer Prev Res (Phila) 8, 743–750, 2015.
32. Pan P, Skaer CW, Wang HT, Stirdivant SM, Young MR, et al.: Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles. Carcinogenesis 36, 1245–1253, 2015.
33. Wang LS, Kuo CT, Huang TH, Yearsley M, Oshima K, et al.: Black raspberries protectively regulate methylation of Wnt pathway genes in precancerous colon tissue. Cancer Prev Res (Phila) 6, 1317–1327, 2013.
34. Wang LS, Kuo CT, Stoner K, Yearsley M, Oshima K, et al.: Dietary black raspberries modulate DNA methylation in dextran sodium sulfate (DSS)-induced ulcerative colitis. Carcinogenesis 34, 2842–2850, 2013.
35. Pan P, C WS, Wang HT, Oshima K, Huang YW, et al.: Loss of free fatty acid receptor 2 enhances colonic adenoma development and reduces the chemopreventive effects of black raspberries in ApcMin/+ mice. Carcinogenesis 38, 86–93, 2017.
36. Pan P, Skaer CW, Wang HT, Kreiser MA, Stirdivant SM, et al.: Systemic metabolite changes in wild-type C57BL/6 mice fed black raspberries. Nutr Cancer 69, 299–306, 2017.
37. Sobhani I, Tap J, Roudot-Thoraval F, Roperch JP, Letulle S, et al.: Microbial dysbiosis in colorectal cancer (CRC) patients. PLoS ONE 6, e16393, 2011.
38. Shen XJ, Rawls JF, Randall T, Burcal L, Mpande CN, et al.: Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas. Gut Microbes 1, 138–147, 2010.
39. Derrien M, Belzer C, de Vos WM, : Akkermansia muciniphila and its role in regulating host functions. Microb Pathog 2016.
40. Zhao S, Liu W, Wang J, Shi J, Sun Y, et al.: Akkermansia muciniphila improves metabolic profiles by reducing inflammation in chow diet-fed mice. J Mol Endocrinol 2016.
41. Song H, Chu Q, Yan F, Yang Y, Han W, et al.: Red pitaya betacyanins protects from diet-induced obesity, liver steatosis and insulin resistance in association with modulation of gut microbiota in mice. J Gastroenterol Hepatol 31, 1462–1469, 2016.
42. Liu W, Crott JW, Lyu L, Pfalzer AC, Li J, et al.: Diet- and genetically-induced obesity produces alterations in the microbiome, inflammation and Wnt pathway in the intestine of Apc+/1638N mice: comparisons and contrasts. J Cancer 7, 1780–1790, 2016.
43. Peiffer DS, Zimmerman NP, Wang LS, Ransom BW, Carmella SG, et al.: Chemoprevention of esophageal cancer with black raspberries, their component anthocyanins, and a major anthocyanin metabolite, protocatechuic acid. Cancer Prev Res (Phila) 7, 574–584, 2014.
44. Peiffer DS, Wang LS, Zimmerman NP, Ransom BW, Carmella SG, et al.: Dietary consumption of black raspberries or their anthocyanin constituents alters innate immune cell trafficking in esophageal cancer. Cancer Immunol Res 4, 72–82, 2016.
45. Riviere A, Selak M, Lantin D, Leroy F, De Vuyst L, : Bifidobacteria and butyrate-producing colon bacteria: importance and strategies for their stimulation in the human gut. Front Microbiol 7, 979, 2016.
46. Elli M, Cattivelli D, Soldi S, Bonatti M, Morelli L, : Evaluation of prebiotic potential of refined psyllium (Plantago ovata) fiber in healthy women. J Clin Gastroenterol 42(Suppl 3 Pt 2), S174–S176, 2008.
47. David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, et al.: Diet rapidly and reproducibly alters the human gut microbiome. Nature 505, 559–563, 2014.
48. Duncan SH, Louis P, Thomson JM, Flint HJ, : The role of pH in determining the species composition of the human colonic microbiota. Environ Microbiol 11, 2112–2122, 2009.
49. De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M, Poullet JB, et al.: Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 107, 14691–14696, 2010.