메뉴 건너뛰기




Volumn 9, Issue 7, 2017, Pages

Effects of aged garlic extract on cholinergic, glutamatergic and GABAergic systems with regard to cognitive impairment in Aβ-induced rats

Author keywords

Aged garlic extract; Alzheimer s disease; Amyloid ; Cholinergic neurons; Glutamate decarboxylase; Radial arm maze; Vesicular glutamate transporters

Indexed keywords

AMYLOID BETA PROTEIN; GARLIC EXTRACT; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR GLUTAMATE TRANSPORTER 2; 4 AMINOBUTYRIC ACID; ACETYLCHOLINE; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; PLANT EXTRACT; SLC17A6 PROTEIN, RAT; SLC17A7 PROTEIN, RAT;

EID: 85021914499     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu9070686     Document Type: Article
Times cited : (46)

References (59)
  • 4
    • 0028271089 scopus 로고
    • Neurochemical histopathological and mnemonic effects of combined lesions of the medial septal and serotonin afferents to the hippocampus
    • Murtha, S.J.; Pappas, B.A. Neurochemical histopathological and mnemonic effects of combined lesions of the medial septal and serotonin afferents to the hippocampus. Brain. Res. 1994, 651, 16–26.
    • (1994) Brain. Res. , vol.651 , pp. 16-26
    • Murtha, S.J.1    Pappas, B.A.2
  • 5
    • 0029917059 scopus 로고    scopus 로고
    • Low-frequency stimulation at the troughs of theta-oscillation induces long-term depression of previously potentiated ca1 synapses
    • Huerta, P.T.; Lisman, J.E. Low-frequency stimulation at the troughs of theta-oscillation induces long-term depression of previously potentiated ca1 synapses. J. Neurophysiol. 1996, 75, 877–884.
    • (1996) J. Neurophysiol. , vol.75 , pp. 877-884
    • Huerta, P.T.1    Lisman, J.E.2
  • 7
    • 27544493516 scopus 로고    scopus 로고
    • Postnatal changes of vesicular glutamate transporter (VGLUT)1 and VGLUT2 immunoreactivities and their colocalization in the mouse forebrain
    • Nakamura, K.; Hioki, H.; Fujiyama, F.; Kaneko, T. Postnatal changes of vesicular glutamate transporter (VGLUT)1 and VGLUT2 immunoreactivities and their colocalization in the mouse forebrain. J. Comp. Neurol. 2005, 492, 263–288.
    • (2005) J. Comp. Neurol. , vol.492 , pp. 263-288
    • Nakamura, K.1    Hioki, H.2    Fujiyama, F.3    Kaneko, T.4
  • 8
    • 33846086092 scopus 로고    scopus 로고
    • Vessicular glutamate transporters 1 and 2 are differentially associated with auditory nerve and spinal trigeminal inputs to the cochlear nucleus
    • Zhou, J.; Nannapaneni, N.; Shore, S. Vessicular glutamate transporters 1 and 2 are differentially associated with auditory nerve and spinal trigeminal inputs to the cochlear nucleus. J. Comp. Neurol. 2007, 500, 777– 787.
    • (2007) J. Comp. Neurol. , vol.500
    • Zhou, J.1    Nannapaneni, N.2    Shore, S.3
  • 9
    • 0037243740 scopus 로고    scopus 로고
    • The expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in neurochemically defined axonal populations in the rat spinal cord with emphasis on the dorsal horn
    • Todd, A.J.; Hughes, D.I.; Polgar, E.; Nagy, G.G.; Mackie, M.; Ottersen, O.P.; Maxwell, D.J. The expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in neurochemically defined axonal populations in the rat spinal cord with emphasis on the dorsal horn. Eu. J. Neurosci. 2003, 17, 13–27.
    • (2003) Eu. J. Neurosci. , vol.17 , pp. 13-27
    • Todd, A.J.1    Hughes, D.I.2    Polgar, E.3    Nagy, G.G.4    Mackie, M.5    Ottersen, O.P.6    Maxwell, D.J.7
  • 10
    • 34250869056 scopus 로고    scopus 로고
    • Role of gabaergic inhibition in hippocampal network oscillations
    • Mann, E.O.; Paulsen, O. Role of gabaergic inhibition in hippocampal network oscillations. Trends Neurosci. 2007, 30, 343–349.
    • (2007) Trends Neurosci , vol.30 , pp. 343-349
    • Mann, E.O.1    Paulsen, O.2
  • 11
    • 0032970415 scopus 로고    scopus 로고
    • Regional distribution and relative amounts of glutamate decarboxylase isoforms in rat and mouse brain
    • Sheikh, S.N.; Martin, S.B.; Martin, D.L. Regional distribution and relative amounts of glutamate decarboxylase isoforms in rat and mouse brain. Neurochem. Int. 1999, 35, 73–80.
    • (1999) Neurochem. Int. , vol.35 , pp. 73-80
    • Sheikh, S.N.1    Martin, S.B.2    Martin, D.L.3
  • 12
    • 10944220717 scopus 로고    scopus 로고
    • The role of the hippocampus in the retrieval of a spatial location
    • Kirwan, C.B.; Gilbert, P.E.; Kesner, R.P. The role of the hippocampus in the retrieval of a spatial location. Neurobiol. Learn. Mem. 2005, 83, 65–71.
    • (2005) Neurobiol. Learn. Mem. , vol.83 , pp. 65-71
    • Kirwan, C.B.1    Gilbert, P.E.2    Kesner, R.P.3
  • 13
    • 51749083458 scopus 로고    scopus 로고
    • Interaction between glutamatergic-NMDA and cholinergic-muscarinic systems in classical fear conditioning
    • Figueredo, L.Z.P.; Moreira, K.M.; Ferreira, T.L.; Fornari, R.V.; Oliveira, M.G.M. Interaction between glutamatergic-NMDA and cholinergic-muscarinic systems in classical fear conditioning. Brain. Res. Bull. 2008, 77, 71–76.
    • (2008) Brain. Res. Bull. , vol.77 , pp. 71-76
    • Figueredo, L.Z.P.1    Moreira, K.M.2    Ferreira, T.L.3    Fornari, R.V.4    Oliveira, M.G.M.5
  • 14
    • 10044257458 scopus 로고    scopus 로고
    • Glutamate and GABA receptor signalling in the developing brain
    • Lujan, R.; Shigemoto, R.; Lopez-Bendito, G. Glutamate and GABA receptor signalling in the developing brain. Neuroscience 2005, 130, 567–580.
    • (2005) Neuroscience , vol.130 , pp. 567-580
    • Lujan, R.1    Shigemoto, R.2    Lopez-Bendito, G.3
  • 15
    • 67649656254 scopus 로고    scopus 로고
    • Effects of chronic noise exposure on spatial learning and memory of rats in relation to neurotransmitters and NMDAR2B alteration in the hippocampus
    • Cui, B.; Wu, M.Q.; She, X.J. Effects of chronic noise exposure on spatial learning and memory of rats in relation to neurotransmitters and NMDAR2B alteration in the hippocampus. J. Occup. Health 2009, 51, 152– 158.
    • (2009) J. Occup. Health , vol.51
    • Cui, B.1    Wu, M.Q.2    She, X.J.3
  • 16
    • 0141483708 scopus 로고    scopus 로고
    • Glutamatergic systems in Alzheimer’s disease
    • Francis, P.T. Glutamatergic systems in Alzheimer’s disease. Int. J. Geriatr. Psych. 2003, 18, S15–S21.
    • (2003) Int. J. Geriatr. Psych. , vol.18 , pp. S15-S21
    • Francis, P.T.1
  • 17
    • 0023707568 scopus 로고
    • Gamma-aminobutyric acid concentration in brain tissue at two stages of Alzheimer’s disease
    • Lowe, S.L.; Francis, P.T.; Procter, A.W.; Palmer, A.M.; Davison, A.N.; Bowen, D.M. Gamma-aminobutyric acid concentration in brain tissue at two stages of Alzheimer’s disease. Brain 1988, 111, 785–799.
    • (1988) Brain , vol.111 , pp. 785-799
    • Lowe, S.L.1    Francis, P.T.2    Procter, A.W.3    Palmer, A.M.4    Davison, A.N.5    Bowen, D.M.6
  • 18
    • 84947918858 scopus 로고    scopus 로고
    • Treatment options in alzheimer s disease: The GABA story
    • Solas, M.; Puerta, E.; Ramirez, M.J. Treatment options in alzheimer s disease: The GABA story. Curr. Pharm. Des. 2015, 21, 4960–4971.
    • (2015) Curr. Pharm. Des. , vol.21 , pp. 4960-4971
    • Solas, M.1    Puerta, E.2    Ramirez, M.J.3
  • 19
    • 79952622790 scopus 로고    scopus 로고
    • Genistein ameliorates learning and memory deficits in amyloid beta(1-40) rat model of Alzheimer’s disease
    • Bagheri, M.; Joghataei, M.T.; Mohseni, S.; Roghani, M. Genistein ameliorates learning and memory deficits in amyloid beta(1-40) rat model of Alzheimer’s disease. Neurobiol. Learn. Mem. 2011, 95, 270–276.
    • (2011) Neurobiol. Learn. Mem. , vol.95 , pp. 270-276
    • Bagheri, M.1    Joghataei, M.T.2    Mohseni, S.3    Roghani, M.4
  • 20
    • 33751427701 scopus 로고    scopus 로고
    • Caffeine and adenosine a(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice
    • Dall'Igna, O.P.; Fett, P.; Gomes, M.W.; Souza, D.O.; Cunha, R.A.; Lara, D.R. Caffeine and adenosine a(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice. Exp. Neurol. 2007, 203, 241–245.
    • (2007) Exp. Neurol. , vol.203 , pp. 241-245
    • Dall'igna, O.P.1    Fett, P.2    Gomes, M.W.3    Souza, D.O.4    Cunha, R.A.5    Lara, D.R.6
  • 24
    • 0035503597 scopus 로고    scopus 로고
    • The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
    • Lim, G.P.; Chu, T.; Yang, F.S.; Beech, W.; Frautschy, S.A.; Cole, G.M. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 2001, 21, 8370– 8377.
    • (2001) J. Neurosci. , vol.21
    • Lim, G.P.1    Chu, T.2    Yang, F.S.3    Beech, W.4    Frautschy, S.A.5    Cole, G.M.6
  • 25
    • 84886592954 scopus 로고    scopus 로고
    • Predominant loss of glutamatergic terminal markers in a beta-amyloid peptide model of Alzheimer’s disease
    • Canas, P.M.; Simoes, A.P.; Rodrigues, R.J.; Cunha, R.A. Predominant loss of glutamatergic terminal markers in a beta-amyloid peptide model of Alzheimer’s disease. Neuropharmacology 2014, 76, 51–56.
    • (2014) Neuropharmacology , vol.76 , pp. 51-56
    • Canas, P.M.1    Simoes, A.P.2    Rodrigues, R.J.3    Cunha, R.A.4
  • 26
    • 79954415024 scopus 로고    scopus 로고
    • L-cysteine treatment in the neuronal culture and APP-Tg mouse model
    • L-cysteine treatment in the neuronal culture and APP-Tg mouse model. J. Neurochem. 2011, 117, 388–402.
    • (2011) J. Neurochem. , vol.117 , pp. 388-402
    • Ray, B.1    Chauhan, N.B.2    Lahiri, D.K.3
  • 27
    • 0029932180 scopus 로고    scopus 로고
    • Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse
    • Moriguchi, T.; Saito, H.; Nishiyama, N. Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse. Biol. Pharm. Bull. 1996, 19, 305–307.
    • (1996) Biol. Pharm. Bull. , vol.19 , pp. 305-307
    • Moriguchi, T.1    Saito, H.2    Nishiyama, N.3
  • 28
  • 29
    • 0030902690 scopus 로고    scopus 로고
    • Anti-ageing effect of aged garlic extract in the inbred brain atrophy mouse model
    • Moriguchi, T.; Saito, H.; Nishiyama, N. Anti-ageing effect of aged garlic extract in the inbred brain atrophy mouse model. Clin. Exp. Pharmacol. Physiol. 1997, 24, 235–242.
    • (1997) Clin. Exp. Pharmacol. Physiol. , vol.24 , pp. 235-242
    • Moriguchi, T.1    Saito, H.2    Nishiyama, N.3
  • 30
    • 34547553090 scopus 로고    scopus 로고
    • Spatial cognition and memory: A reversible lesion with lidocaine into the anteromedial/posterior parietal cortex (AM/PPC) affects differently working and long-term memory on two foraging tasks
    • Espina-Marchant, P.; Pinto-Hamuy, T.; Bustamante, D.; Morales, P.; Robles, L.; Herrera-Marschitz, M. Spatial cognition and memory: A reversible lesion with lidocaine into the anteromedial/posterior parietal cortex (AM/PPC) affects differently working and long-term memory on two foraging tasks. Biol. Res. 2006, 39, 601–609.
    • (2006) Biol. Res. , vol.39 , pp. 601-609
    • Espina-Marchant, P.1    Pinto-Hamuy, T.2    Bustamante, D.3    Morales, P.4    Robles, L.5    Herrera-Marschitz, M.6
  • 31
    • 33644823580 scopus 로고    scopus 로고
    • Stimulation of neurogenesis in the hippocampus of the adult rat by fluoxetine requires rhythmic change in corticosterone
    • Huang, G.J.; Herbert, J. Stimulation of neurogenesis in the hippocampus of the adult rat by fluoxetine requires rhythmic change in corticosterone. Biol. Psychiat. 2006, 59, 619–624.
    • (2006) Biol. Psychiat. , vol.59 , pp. 619-624
    • Huang, G.J.1    Herbert, J.2
  • 32
    • 48249126198 scopus 로고    scopus 로고
    • 5-fluorouracil chemotherapy affects spatial working memory and newborn neurons in the adult rat hippocampus
    • Mustafa, S.; Walker, A.; Bennett, G.; Wigmore, P.M. 5-fluorouracil chemotherapy affects spatial working memory and newborn neurons in the adult rat hippocampus. Eur. J. Neurosci. 2008, 28, 323–330.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 323-330
    • Mustafa, S.1    Walker, A.2    Bennett, G.3    Wigmore, P.M.4
  • 33
    • 0030513943 scopus 로고    scopus 로고
    • Structural correlates of cognition in dementia: Quantification and assessment of synapse change
    • DeKosky, S.T.; Scheff, S.W.; Styren, S.D. Structural correlates of cognition in dementia: Quantification and assessment of synapse change. Neurodegeneration 1996, 5, 417–421.
    • (1996) Neurodegeneration , vol.5 , pp. 417-421
    • Dekosky, S.T.1    Scheff, S.W.2    Styren, S.D.3
  • 34
    • 0036810329 scopus 로고    scopus 로고
    • Alzheimer’s disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies
    • Auld, D.S.; Kornecook, T.J.; Bastianetto, S.; Quirion, R. Alzheimer’s disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies. Prog. Neurobiol. 2002, 68, 209–245.
    • (2002) Prog. Neurobiol. , vol.68 , pp. 209-245
    • Auld, D.S.1    Kornecook, T.J.2    Bastianetto, S.3    Quirion, R.4
  • 35
    • 0032031815 scopus 로고    scopus 로고
    • Gabaergic deafferentation hypothesis of brain aging and Alzheimer’s disease revisited
    • Marczynski, T.J. Gabaergic deafferentation hypothesis of brain aging and Alzheimer’s disease revisited. Brain. Res. Bull. 1998, 45, 341–379.
    • (1998) Brain. Res. Bull. , vol.45 , pp. 341-379
    • Marczynski, T.J.1
  • 36
    • 34249027009 scopus 로고    scopus 로고
    • Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer’s disease: Relevance for the behavioral and synaptic deficits induced by amyloid beta protein
    • Medeiros, R.; Prediger, R.D.S.; Passos, G.F.; Pandolfo, P.; Duarte, F.S.; Franco, J.L.; Dafre, A.L.; Di Giunta, G.; Figueiredo, C.P.; Takahashi, R.N.; et al. Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer’s disease: Relevance for the behavioral and synaptic deficits induced by amyloid beta protein. J. Neurosci. 2007, 27, 5394–5404.
    • (2007) J. Neurosci. , vol.27 , pp. 5394-5404
    • Medeiros, R.1    Prediger, R.D.S.2    Passos, G.F.3    Pandolfo, P.4    Duarte, F.S.5    Franco, J.L.6    Dafre, A.L.7    Di Giunta, G.8    Figueiredo, C.P.9    Takahashi, R.N.10
  • 37
    • 72449208698 scopus 로고    scopus 로고
    • Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway
    • Canas, P.M.; Porciuncula, L.O.; Cunha, G.M.A.; Silva, C.G.; Machado, N.J.; Oliveira, J.M.A.; Oliveira, C.R.; Cunha, R.A. Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway. J. Neurosci. 2009, 29, 14741– 14751.
    • (2009) J. Neurosci , vol.29
    • Canas, P.M.1    Porciuncula, L.O.2    Cunha, G.M.A.3    Silva, C.G.4    Machado, N.J.5    Oliveira, J.M.A.6    Oliveira, C.R.7    Cunha, R.A.8
  • 38
    • 0031051960 scopus 로고    scopus 로고
    • Continuous infusion of beta-amyloid protein into the rat cerebral ventricle induces learning impairment and neuronal and morphological degeneration
    • Nitta, A.; Fukuta, T.; Hasegawa, T.; Nabeshima, T. Continuous infusion of beta-amyloid protein into the rat cerebral ventricle induces learning impairment and neuronal and morphological degeneration. Jpn. J. Pharmacol. 1997, 73, 51–57.
    • (1997) Jpn. J. Pharmacol. , vol.73 , pp. 51-57
    • Nitta, A.1    Fukuta, T.2    Hasegawa, T.3    Nabeshima, T.4
  • 39
    • 84861727534 scopus 로고    scopus 로고
    • Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-beta peptide oligomers
    • Nunes-Tavares, N.; Santos, L.E.; Stutz, B.; Brito-Moreira, J.; Klein, W.L.; Ferreira, S.T.; de Mello, F.G. Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-beta peptide oligomers. J. Biol. Chem. 2012, 287, 19377–19385.
    • (2012) J. Biol. Chem. , vol.287 , pp. 19377-19385
    • Nunes-Tavares, N.1    Santos, L.E.2    Stutz, B.3    Brito-Moreira, J.4    Klein, W.L.5    Ferreira, S.T.6    De Mello, F.G.7
  • 40
    • 84993940197 scopus 로고    scopus 로고
    • Intrinsic cholinergic neurons in the hippocampus: Fact or artifact?
    • Blusztajn, J.K.; Rinnofner, J. Intrinsic cholinergic neurons in the hippocampus: Fact or artifact? Front. Synaptic Neurosci. 2016, 8, 6.
    • (2016) Front. Synaptic Neurosci. , vol.8 , pp. 6
    • Blusztajn, J.K.1    Rinnofner, J.2
  • 41
    • 0022553941 scopus 로고
    • Cholinergic neurons in the hippocampus. A combined light- and electron-microscopic immunocytochemical study in the rat
    • Frotscher, M.; Schlander, M.; Léránth, C. Cholinergic neurons in the hippocampus. A combined light- and electron-microscopic immunocytochemical study in the rat. Cell. Tissue. Res. 1986, 246, 293–301.
    • (1986) Cell. Tissue. Res. , vol.246 , pp. 293-301
    • Frotscher, M.1    Schlander, M.2    Léránth, C.3
  • 42
    • 0023888467 scopus 로고
    • Cholinergic neurons within the rat hippocampus: Response to fimbria-fornix transection
    • Blaker, S.N.; Armstrong, D.M.; Gage F.H. Cholinergic neurons within the rat hippocampus: Response to fimbria-fornix transection. J. Comp. Neurol. 1988, 272, 127–138.
    • (1988) J. Comp. Neurol. , vol.272 , pp. 127-138
    • Blaker, S.N.1    Armstrong, D.M.2    Gage, F.H.3
  • 43
    • 0023119044 scopus 로고
    • An immunocytochemical study of choline acetyltransferase-containing neurons and axon terminals in normal and partially deafferented hippocampal formation
    • Matthews, D.A.; Salvaterra, P.M.; Crawford, G.D.; Houser, C.R.; Vaughn, J.E. An immunocytochemical study of choline acetyltransferase-containing neurons and axon terminals in normal and partially deafferented hippocampal formation. Brain. Res. 1987, 402, 30–43.
    • (1987) Brain. Res. , vol.402 , pp. 30-43
    • Matthews, D.A.1    Salvaterra, P.M.2    Crawford, G.D.3    Houser, C.R.4    Vaughn, J.E.5
  • 44
    • 84942376390 scopus 로고    scopus 로고
    • Hippocampal “cholinergic interneurons” visualized with the choline acetyltransferase promoter: Anatomical distribution, intrinsic membrane properties, neurochemical characteristics, and capacity for cholinergic modulation
    • Yi, F.; Catudio-Garrett, E.; Gabriel, R.; Wilhelm, M.; Erdelyi, F.; Szabo, G.; Deisseroth, K.; Lawrence, J. Hippocampal “cholinergic interneurons” visualized with the choline acetyltransferase promoter: Anatomical distribution, intrinsic membrane properties, neurochemical characteristics, and capacity for cholinergic modulation. Front. Synaptic. Neurosci. 2015, 7, 4.
    • (2015) Front. Synaptic. Neurosci. , vol.7 , pp. 4
    • Yi, F.1    Catudio-Garrett, E.2    Gabriel, R.3    Wilhelm, M.4    Erdelyi, F.5    Szabo, G.6    Deisseroth, K.7    Lawrence, J.8
  • 45
    • 0033953377 scopus 로고    scopus 로고
    • Evidence for the existence of non-gabaergic, cholinergic interneurons in the rodent hippocampus
    • Frotscher, M.; Vida, I.; Bender, R. Evidence for the existence of non-gabaergic, cholinergic interneurons in the rodent hippocampus. Neuroscience 2000, 96, 27–31.
    • (2000) Neuroscience , vol.96 , pp. 27-31
    • Frotscher, M.1    Vida, I.2    Bender, R.3
  • 46
    • 0033559842 scopus 로고    scopus 로고
    • Synaptic transmission at nicotinic acetylcholine receptors in rat hippocampal organotypic cultures and slices
    • Hefft, S.; Hulo, S.; Bertrand, D.; Muller, D. Synaptic transmission at nicotinic acetylcholine receptors in rat hippocampal organotypic cultures and slices. J. Physiol. 1999, 515, 769–776.
    • (1999) J. Physiol. , vol.515 , pp. 769-776
    • Hefft, S.1    Hulo, S.2    Bertrand, D.3    Muller, D.4
  • 47
    • 0345096618 scopus 로고    scopus 로고
    • Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology
    • Bell, K.F.S.; de Kort, G.J.L.; Steggerda, S.; Shigemoto, R.; Ribeiro-da-Silva, A.; Cuello, A.C. Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology. Neurosci. Lett. 2003, 353, 143–147.
    • (2003) Neurosci. Lett. , vol.353 , pp. 143-147
    • Bell, K.F.S.1    De Kort, G.J.L.2    Steggerda, S.3    Shigemoto, R.4    Ribeiro-Da-Silva, A.5    Cuello, A.C.6
  • 49
    • 0032458593 scopus 로고    scopus 로고
    • Functional relationship between age-related immunodeficiency and learning deterioration
    • Zhang, Y.X.; Moriguchi, T.; Saito, H.; Nishiyama, N. Functional relationship between age-related immunodeficiency and learning deterioration. Eur. J. Neurosci. 1998, 10, 3869–3875.
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 3869-3875
    • Zhang, Y.X.1    Moriguchi, T.2    Saito, H.3    Nishiyama, N.4
  • 50
    • 58149498818 scopus 로고    scopus 로고
    • Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: Relevance to Alzheimer’s disease
    • Gupta, V.B.; Indi, S.S.; Rao, K.S. Garlic extract exhibits antiamyloidogenic activity on amyloid-beta fibrillogenesis: Relevance to Alzheimer’s disease. Phytother. Res. 2009, 23, 111–115.
    • (2009) Phytother. Res. , vol.23 , pp. 111-115
    • Gupta, V.B.1    Indi, S.S.2    Rao, K.S.3
  • 51
    • 64549091520 scopus 로고    scopus 로고
    • Comparative evaluation of adenosine deaminase activity in cerebral cortex and hippocampus of young and adult rats: Effect of garlic extract (Allium sativum L.) on their susceptibility to heavy metal exposure
    • Belle, L.P.; de Bona, K.S.; Abdalla, F.H.; Pimentel, V.C.; Pigatto, A.S.; Moretto, M.B. Comparative evaluation of adenosine deaminase activity in cerebral cortex and hippocampus of young and adult rats: Effect of garlic extract (Allium sativum L.) on their susceptibility to heavy metal exposure. Basic Clin. Pharmacol. Toxicol. 2009, 104, 408–413.
    • (2009) Basic Clin. Pharmacol. Toxicol. , vol.104 , pp. 408-413
    • Belle, L.P.1    De Bona, K.S.2    Abdalla, F.H.3    Pimentel, V.C.4    Pigatto, A.S.5    Moretto, M.B.6
  • 52
    • 84863269708 scopus 로고    scopus 로고
    • Involvement of adenosine and standardization of aqueous extract of garlic (Allium sativum Linn.) on cardioprotective and cardiodepressant properties in ischemic preconditioning and myocardial ischemia-reperfusion induced cardiac injury
    • Sharma, A.K.; Munajjam, A.; Vaishnav, B.; Sharma, R.; Sharma, A.; Kishore, K.; Sharma, A.; Sharma, D.; Kumari, R.; Tiwari, A.; et al. Involvement of adenosine and standardization of aqueous extract of garlic (Allium sativum Linn.) on cardioprotective and cardiodepressant properties in ischemic preconditioning and myocardial ischemia-reperfusion induced cardiac injury. J. Biomed. Res 2012, 26, 24–36.
    • (2012) J. Biomed. Res , vol.26 , pp. 24-36
    • Sharma, A.K.1    Munajjam, A.2    Vaishnav, B.3    Sharma, R.4    Sharma, A.5    Kishore, K.6    Sharma, A.7    Sharma, D.8    Kumari, R.9    Tiwari, A.10
  • 53
    • 0024364877 scopus 로고
    • Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease
    • Masliah, E.; Terry, R.D.; DeTeresa, R.M.; Hansen, L.A. Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease. Neurosci. Lett. 1989, 103, 234–239.
    • (1989) Neurosci. Lett. , vol.103 , pp. 234-239
    • Masliah, E.1    Terry, R.D.2    Deteresa, R.M.3    Hansen, L.A.4
  • 54
    • 0034656234 scopus 로고    scopus 로고
    • Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer’s disease brains
    • Sze, C.I.; Bi, H.; Kleinschmidt-DeMasters, B.K.; Filley, C.M.; Martin, L.J. Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer’s disease brains. J. Neurol. Sci. 2000, 175, 81–90.
    • (2000) J. Neurol. Sci. , vol.175 , pp. 81-90
    • Sze, C.I.1    Bi, H.2    Kleinschmidt-Demasters, B.K.3    Filley, C.M.4    Martin, L.J.5
  • 55
    • 61749093782 scopus 로고    scopus 로고
    • Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-beta (25– 35)
    • Limon, I.D.; Mendieta, L.; Diaz, A.; Chamorro, G.; Espinosa, B.; Zenteno, E.; Guevara, J. Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-beta (25– 35). Neurosci. Lett. 2009, 453, 98–103.
    • (2009) Neurosci. Lett. , vol.453 , pp. 98-103
    • Limon, I.D.1    Mendieta, L.2    Diaz, A.3    Chamorro, G.4    Espinosa, B.5    Zenteno, E.6    Guevara, J.7
  • 56
    • 70349706154 scopus 로고    scopus 로고
    • Amyloid beta and impairment in multiple memory systems in older transgenic APP TgCRND8 mice
    • Hanna, A.; Horne, P.; Yager, D.; Eckman, C.; Eckman, E.; Janus, C. Amyloid beta and impairment in multiple memory systems in older transgenic APP TgCRND8 mice. Genes. Brain. Behav. 2009, 8, 676–684.
    • (2009) Genes. Brain. Behav. , vol.8 , pp. 676-684
    • Hanna, A.1    Horne, P.2    Yager, D.3    Eckman, C.4    Eckman, E.5    Janus, C.6
  • 57
    • 84880759156 scopus 로고    scopus 로고
    • Neurotoxicity of amyloid beta-protein: Synaptic and network dysfunction
    • Mucke, L.; Selkoe, D.J. Neurotoxicity of amyloid beta-protein: Synaptic and network dysfunction. Csh. Perspect. Med. 2012, 2, doi:10.1101/cshperspect.a006338.
    • (2012) Csh. Perspect. Med. , vol.2
    • Mucke, L.1    Selkoe, D.J.2
  • 59
    • 84901865665 scopus 로고    scopus 로고
    • Use of an eight-arm radial water maze to assess working and reference memory following neonatal brain injury
    • Penley, S.C.; Gaudet, C.M.; Threlkeld, S.W. Use of an eight-arm radial water maze to assess working and reference memory following neonatal brain injury. J. Vis. Exp. 2013, doi:10.3791/50940.
    • (2013) J. Vis. Exp.
    • Penley, S.C.1    Gaudet, C.M.2    Threlkeld, S.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.