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Volumn 8, Issue MAR, 2016, Pages

Intrinsic cholinergic neurons in the hippocampus: Fact or artifact?

Author keywords

Acetylcholine; Basal forebrain cholinergic neurons; Choline acetyltransferase ChAT; Hippocampus; Septum; Slc18a3; Transgenic mouse models; Vesicular acetylcholine transporter

Indexed keywords

ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; CRE RECOMBINASE; VESICULAR ACETYLCHOLINE TRANSPORTER;

EID: 84993940197     PISSN: None     EISSN: 16633563     Source Type: Journal    
DOI: 10.3389/fnsyn.2016.00006     Document Type: Article
Times cited : (12)

References (75)
  • 1
    • 84919951631 scopus 로고    scopus 로고
    • Regulation and function of adult neurogenesis: from genes to cognition
    • Aimone, J. B., Li, Y., Lee, S. W., Clemenson, G. D., Deng, W., and Gage, F. H. (2014). Regulation and function of adult neurogenesis: from genes to cognition. Physiol. Rev. 94, 991-1026. doi: 10.1152/physrev.00004.2014
    • (2014) Physiol. Rev , vol.94 , pp. 991-1026
    • Aimone, J.B.1    Li, Y.2    Lee, S.W.3    Clemenson, G.D.4    Deng, W.5    Gage, F.H.6
  • 2
    • 0020574342 scopus 로고
    • Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase
    • Armstrong, D. M., Saper, C. B., Levey, A. I., Wainer, B. H., and Terry, R. D. (1983). Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase. J. Comp. Neurol. 216, 53-68. doi: 10.1002/cne.902160106
    • (1983) J. Comp. Neurol , vol.216 , pp. 53-68
    • Armstrong, D.M.1    Saper, C.B.2    Levey, A.I.3    Wainer, B.H.4    Terry, R.D.5
  • 4
    • 33947242735 scopus 로고    scopus 로고
    • Extensive training in a maze task reduces neurogenesis in the adult rat dentate gyrus probably as a result of stress
    • Aztiria, E., Capodieci, G., Arancio, L., and Leanza, G. (2007). Extensive training in a maze task reduces neurogenesis in the adult rat dentate gyrus probably as a result of stress. Neurosci. Lett. 416, 133-137. doi: 10.1016/j.neulet.2007.01.069
    • (2007) Neurosci. Lett , vol.416 , pp. 133-137
    • Aztiria, E.1    Capodieci, G.2    Arancio, L.3    Leanza, G.4
  • 5
    • 0029082673 scopus 로고
    • Co-ordinated up-regulation of choline acetyltransferase and vesicular acetylcholine transporter gene expression by the retinoic acid receptor alpha, cAMP and CNTF/LIF signaling pathways in a murine septal cell line
    • Berse, B., and Blusztajn, J. K. (1995). Co-ordinated up-regulation of choline acetyltransferase and vesicular acetylcholine transporter gene expression by the retinoic acid receptor alpha, cAMP and CNTF/LIF signaling pathways in a murine septal cell line. J. Biol. Chem. 270, 22101-22104. doi: 10.1074/jbc.270.38.22101
    • (1995) J. Biol. Chem , vol.270 , pp. 22101-22104
    • Berse, B.1    Blusztajn, J.K.2
  • 6
    • 39449093617 scopus 로고    scopus 로고
    • The hippocampus and memory: insights from spatial processing
    • Bird, C. M., and Burgess, N. (2008). The hippocampus and memory: insights from spatial processing. Nat. Rev. Neurosci. 9, 182-194. doi: 10.1038/nrn2335
    • (2008) Nat. Rev. Neurosci , vol.9 , pp. 182-194
    • Bird, C.M.1    Burgess, N.2
  • 7
    • 0023888467 scopus 로고
    • Cholinergic neurons within the rat hippocampus: response to fimbria-fornix transection
    • Blaker, S. N., Armstrong, D. M., and Gage, F. H. (1988). Cholinergic neurons within the rat hippocampus: response to fimbria-fornix transection. J. Comp. Neurol. 272, 127-138. doi: 10.1002/cne.902720109
    • (1988) J. Comp. Neurol , vol.272 , pp. 127-138
    • Blaker, S.N.1    Armstrong, D.M.2    Gage, F.H.3
  • 8
    • 0020608777 scopus 로고
    • Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease
    • Bowen, D. M., Allen, S. J., Benton, J. S., Goodhardt, M. J., Haan, E. A., Palmer, A. M., et al. (1983). Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease. J. Neurochem. 41, 266-272. doi: 10.1111/j.1471-4159.1983.tb11838.x
    • (1983) J. Neurochem , vol.41 , pp. 266-272
    • Bowen, D.M.1    Allen, S.J.2    Benton, J.S.3    Goodhardt, M.J.4    Haan, E.A.5    Palmer, A.M.6
  • 9
    • 84888338639 scopus 로고    scopus 로고
    • BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease
    • Burke, R. M., Norman, T. A., Haydar, T. F., Slack, B. E., Leeman, S. E., Blusztajn, J. K., et al. (2013). BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U S A 110, 19567-19572. doi: 10.1073/pnas.1319297110
    • (2013) Proc. Natl. Acad. Sci. U S A , vol.110 , pp. 19567-19572
    • Burke, R.M.1    Norman, T.A.2    Haydar, T.F.3    Slack, B.E.4    Leeman, S.E.5    Blusztajn, J.K.6
  • 10
    • 0022365069 scopus 로고
    • Cholinergic innervation of the rat dentate gyrus: an immunocytochemical and electron microscopical study
    • Clarke, D. J. (1985). Cholinergic innervation of the rat dentate gyrus: an immunocytochemical and electron microscopical study. Brain Res. 360, 349-354. doi: 10.1016/0006-8993(85)91253-3
    • (1985) Brain Res , vol.360 , pp. 349-354
    • Clarke, D.J.1
  • 11
    • 3042760266 scopus 로고    scopus 로고
    • Decreased neurogenesis after cholinergic forebrain lesion in the adult rat
    • Cooper-Kuhn, C. M., Winkler, J., and Kuhn, H. G. (2004). Decreased neurogenesis after cholinergic forebrain lesion in the adult rat. J. Neurosci. Res. 77, 155-165. doi: 10.1002/jnr.20116
    • (2004) J. Neurosci. Res , vol.77 , pp. 155-165
    • Cooper-Kuhn, C.M.1    Winkler, J.2    Kuhn, H.G.3
  • 12
    • 84901604220 scopus 로고    scopus 로고
    • Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice
    • Crittenden, J. R., Lacey, C. J., Lee, T., Bowden, H. A., and Graybiel, A. M. (2014). Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice. Front. Neural Circuits 8:57. doi: 10.3389/fncir.2014.00057
    • (2014) Front. Neural Circuits , vol.8 , pp. 57
    • Crittenden, J.R.1    Lacey, C.J.2    Lee, T.3    Bowden, H.A.4    Graybiel, A.M.5
  • 13
    • 0031745813 scopus 로고    scopus 로고
    • The cholinergic gene locus
    • Eiden, L. E. (1998). The cholinergic gene locus. J. Neurochem. 70, 2227-2240. doi: 10.1046/j.1471-4159.1998.70062227.x
    • (1998) J. Neurochem , vol.70 , pp. 2227-2240
    • Eiden, L.E.1
  • 14
    • 32144442520 scopus 로고    scopus 로고
    • Cell proliferation in the adult hippocampal formation of rodents and its modulation by entorhinal and fimbria-fornix afferents
    • Fontana, X., N�cher, J., Soriano, E., and del R�o, J. A. (2006). Cell proliferation in the adult hippocampal formation of rodents and its modulation by entorhinal and fimbria-fornix afferents. Cereb. Cortex 16, 301-312. doi: 10.1093/cercor/bhi120
    • (2006) Cereb. Cortex , vol.16 , pp. 301-312
    • Fontana, X.1    N�cher, J.2    Soriano, E.3    del R�o, J.A.4
  • 15
    • 58349093111 scopus 로고    scopus 로고
    • Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis
    • Fr�chette, M., Rennie, K., and Pappas, B. A. (2009). Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis. Brain Res. 1252, 172-182. doi: 10.1016/j.brainres.2008.11.082
    • (2009) Brain Res , vol.1252 , pp. 172-182
    • Fr�chette, M.1    Rennie, K.2    Pappas, B.A.3
  • 16
    • 0022553941 scopus 로고
    • Cholinergic neurons in the hippocampus. A combined light-and electron-microscopic immunocytochemical study in the rat
    • Frotscher, M., Schlander, M., and L�r�nth, C. (1986). Cholinergic neurons in the hippocampus. A combined light-and electron-microscopic immunocytochemical study in the rat. Cell Tissue Res. 246, 293-301. doi: 10.1007/bf00215891
    • (1986) Cell Tissue Res , vol.246 , pp. 293-301
    • Frotscher, M.1    Schlander, M.2    L�r�nth, C.3
  • 18
    • 0031772148 scopus 로고    scopus 로고
    • Coordinate expression of the vesicular acetylcholine transporter and choline acetyltransferase following septohippocampal pathway lesion
    • Gilmor, M. L., Counts, S. E., Wiley, R. G., and Levey, A. I. (1998). Coordinate expression of the vesicular acetylcholine transporter and choline acetyltransferase following septohippocampal pathway lesion. J. Neurochem. 71, 2411-2420. doi: 10.1046/j.1471-4159.1998.71062411.x
    • (1998) J. Neurochem , vol.71 , pp. 2411-2420
    • Gilmor, M.L.1    Counts, S.E.2    Wiley, R.G.3    Levey, A.I.4
  • 19
    • 0030009912 scopus 로고    scopus 로고
    • Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles
    • Gilmor, M. L., Nash, N. R., Roghani, A., Edwards, R. H., Yi, H., Hersch, S. M., et al. (1996). Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles. J. Neurosci. 16, 2179-2190.
    • (1996) J. Neurosci , vol.16 , pp. 2179-2190
    • Gilmor, M.L.1    Nash, N.R.2    Roghani, A.3    Edwards, R.H.4    Yi, H.5    Hersch, S.M.6
  • 20
    • 34548651693 scopus 로고    scopus 로고
    • Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs
    • Gong, S., Doughty, M., Harbaugh, C. R., Cummins, A., Hatten, M. E., Heintz, N., et al. (2007). Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J. Neurosci. 27, 9817-9823. doi: 10.1523/JNEUROSCI.2707-07.2007
    • (2007) J. Neurosci , vol.27 , pp. 9817-9823
    • Gong, S.1    Doughty, M.2    Harbaugh, C.R.3    Cummins, A.4    Hatten, M.E.5    Heintz, N.6
  • 21
    • 0242401835 scopus 로고    scopus 로고
    • A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
    • Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., et al. (2003). A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425, 917-925. doi: 10.1038/nature02033
    • (2003) Nature , vol.425 , pp. 917-925
    • Gong, S.1    Zheng, C.2    Doughty, M.L.3    Losos, K.4    Didkovsky, N.5    Schambra, U.B.6
  • 22
    • 39649101061 scopus 로고    scopus 로고
    • Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease
    • Goto, Y., Niidome, T., Hongo, H., Akaike, A., Kihara, T., and Sugimoto, H. (2008). Impaired muscarinic regulation of excitatory synaptic transmission in the APPswe/PS1dE9 mouse model of Alzheimer's disease. Eur. J. Pharmacol. 583, 84-91. doi: 10.1016/j.ejphar.2008.01.030
    • (2008) Eur. J. Pharmacol , vol.583 , pp. 84-91
    • Goto, Y.1    Niidome, T.2    Hongo, H.3    Akaike, A.4    Kihara, T.5    Sugimoto, H.6
  • 23
    • 84945445848 scopus 로고    scopus 로고
    • Distinguishing adaptive plasticity from vulnerability in the aging hippocampus
    • Gray, D. T., and Barnes, C. A. (2015). Distinguishing adaptive plasticity from vulnerability in the aging hippocampus. Neuroscience 309, 17-28. doi: 10.1016/j.neuroscience.2015.08.001
    • (2015) Neuroscience , vol.309 , pp. 17-28
    • Gray, D.T.1    Barnes, C.A.2
  • 24
    • 84859492616 scopus 로고    scopus 로고
    • Atrophy of the cholinergic Basal forebrain over the adult age range and in early stages of Alzheimer's disease
    • Grothe, M., Heinsen, H., and Teipel, S. J. (2012). Atrophy of the cholinergic Basal forebrain over the adult age range and in early stages of Alzheimer's disease. Biol. Psychiatry 71, 805-813. doi: 10.1016/j.biopsych.2011.06.019
    • (2012) Biol. Psychiatry , vol.71 , pp. 805-813
    • Grothe, M.1    Heinsen, H.2    Teipel, S.J.3
  • 25
    • 79955972011 scopus 로고    scopus 로고
    • A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons
    • Grybko, M. J., Hahm, E. T., Perrine, W., Parnes, J. A., Chick, W. S., Sharma, G., et al. (2011). A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons. Eur. J. Neurosci. 33, 1786-1798. doi: 10.1111/j.1460-9568.2011.07671.x
    • (2011) Eur. J. Neurosci , vol.33 , pp. 1786-1798
    • Grybko, M.J.1    Hahm, E.T.2    Perrine, W.3    Parnes, J.A.4    Chick, W.S.5    Sharma, G.6
  • 26
    • 84858342780 scopus 로고    scopus 로고
    • Cholinergic system function and cognition in mild cognitive impairment
    • Haense, C., Kalbe, E., Herholz, K., Hohmann, C., Neumaier, B., Krais, R., et al. (2012). Cholinergic system function and cognition in mild cognitive impairment. Neurobiol. Aging 33, 867-877. doi: 10.1016/j.neurobiolaging.2010.08.015
    • (2012) Neurobiol. Aging , vol.33 , pp. 867-877
    • Haense, C.1    Kalbe, E.2    Herholz, K.3    Hohmann, C.4    Neumaier, B.5    Krais, R.6
  • 27
    • 11144357454 scopus 로고    scopus 로고
    • Gene expression nervous system atlas (GENSAT)
    • Heintz, N. (2004). Gene expression nervous system atlas (GENSAT). Nat. Neurosci. 7:483. doi: 10.1038/nn0504-483
    • (2004) Nat. Neurosci , vol.7 , pp. 483
    • Heintz, N.1
  • 28
    • 67650735603 scopus 로고    scopus 로고
    • Effect of voluntary running on adult hippocampal neurogenesis in cholinergic lesioned mice
    • Ho, N. F., Han, S. P., and Dawe, G. S. (2009). Effect of voluntary running on adult hippocampal neurogenesis in cholinergic lesioned mice. BMC Neurosci. 10:57. doi: 10.1186/1471-2202-10-57
    • (2009) BMC Neurosci , vol.10 , pp. 57
    • Ho, N.F.1    Han, S.P.2    Dawe, G.S.3
  • 29
    • 0030800975 scopus 로고    scopus 로고
    • Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: in situ hybridization histochemistry and immunohistochemistry
    • Ichikawa, T., Ajiki, K., Matsuura, J., and Misawa, H. (1997). Localization of two cholinergic markers, choline acetyltransferase and vesicular acetylcholine transporter in the central nervous system of the rat: in situ hybridization histochemistry and immunohistochemistry. J. Chem. Neuroanat. 13, 23-39. doi: 10.1016/s0891-0618(97)00021-5
    • (1997) J. Chem. Neuroanat , vol.13 , pp. 23-39
    • Ichikawa, T.1    Ajiki, K.2    Matsuura, J.3    Misawa, H.4
  • 30
    • 0022569549 scopus 로고
    • Organization of choline acetyltransferase-containing structures in the forebrain of the rat
    • Ichikawa, T., and Hirata, Y. (1986). Organization of choline acetyltransferase-containing structures in the forebrain of the rat. J. Neurosci. 6, 281-292.
    • (1986) J. Neurosci , vol.6 , pp. 281-292
    • Ichikawa, T.1    Hirata, Y.2
  • 31
    • 79953039354 scopus 로고    scopus 로고
    • Cholinergic activation of hippocampal neural stem cells in aged dentate gyrus
    • Itou, Y., Nochi, R., Kuribayashi, H., Saito, Y., and Hisatsune, T. (2011). Cholinergic activation of hippocampal neural stem cells in aged dentate gyrus. Hippocampus 21, 446-459. doi: 10.1002/hipo.20761
    • (2011) Hippocampus , vol.21 , pp. 446-459
    • Itou, Y.1    Nochi, R.2    Kuribayashi, H.3    Saito, Y.4    Hisatsune, T.5
  • 32
    • 0024409878 scopus 로고
    • Transient increase in the number of cholinergic neurons in the developing rat dentate gyrus
    • Kanaya-Ida, S., and Ben Ari, Y. (1989). Transient increase in the number of cholinergic neurons in the developing rat dentate gyrus. Neurosci. Lett. 101, 23-28. doi: 10.1016/0304-3940(89)90434-5
    • (1989) Neurosci. Lett , vol.101 , pp. 23-28
    • Kanaya-Ida, S.1    Ben Ari, Y.2
  • 33
    • 33748883817 scopus 로고    scopus 로고
    • Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb
    • Kaneko, N., Okano, H., and Sawamoto, K. (2006). Role of the cholinergic system in regulating survival of newborn neurons in the adult mouse dentate gyrus and olfactory bulb. Genes Cells 11, 1145-1159. doi: 10.1111/j.1365-2443.2006.01010.x
    • (2006) Genes Cells , vol.11 , pp. 1145-1159
    • Kaneko, N.1    Okano, H.2    Sawamoto, K.3
  • 34
    • 84879135819 scopus 로고    scopus 로고
    • ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains
    • Kolisnyk, B., Guzman, M. S., Raulic, S., Fan, J., Magalh�es, A. C., Feng, G., et al. (2013). ChAT-ChR2-EYFP mice have enhanced motor endurance but show deficits in attention and several additional cognitive domains. J. Neurosci. 33, 10427-10438. doi: 10.1523/JNEUROSCI.0395-13.2013
    • (2013) J. Neurosci , vol.33 , pp. 10427-10438
    • Kolisnyk, B.1    Guzman, M.S.2    Raulic, S.3    Fan, J.4    Magalh�es, A.C.5    Feng, G.6
  • 35
    • 33748760144 scopus 로고    scopus 로고
    • Pharmacological evidence of cholinergic involvement in adult hippocampal neurogenesis in rats
    • Kotani, S., Yamauchi, T., Teramoto, T., and Ogura, H. (2006). Pharmacological evidence of cholinergic involvement in adult hippocampal neurogenesis in rats. Neuroscience 142, 505-514. doi: 10.1016/j.neuroscience.2006.06.035
    • (2006) Neuroscience , vol.142 , pp. 505-514
    • Kotani, S.1    Yamauchi, T.2    Teramoto, T.3    Ogura, H.4
  • 36
    • 50649105722 scopus 로고    scopus 로고
    • Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis
    • Kotani, S., Yamauchi, T., Teramoto, T., and Ogura, H. (2008). Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis. Chem. Biol. Interact. 175, 227-230. doi: 10.1016/j.cbi.2008.04.004
    • (2008) Chem. Biol. Interact , vol.175 , pp. 227-230
    • Kotani, S.1    Yamauchi, T.2    Teramoto, T.3    Ogura, H.4
  • 37
    • 0027498346 scopus 로고
    • In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cord
    • Lauterborn, J. C., Isackson, P. J., Montalvo, R., and Gall, C. M. (1993). In situ hybridization localization of choline acetyltransferase mRNA in adult rat brain and spinal cord. Mol. Brain Res. 17, 59-69. doi: 10.1016/0169-328x(93)90073-X
    • (1993) Mol. Brain Res , vol.17 , pp. 59-69
    • Lauterborn, J.C.1    Isackson, P.J.2    Montalvo, R.3    Gall, C.M.4
  • 38
    • 84855977476 scopus 로고    scopus 로고
    • New neurons in an aged brain
    • Lee, S. W., Clemenson, G. D., and Gage, F. H. (2012). New neurons in an aged brain. Behav. Brain Res. 227, 497-507. doi: 10.1016/j.bbr.2011.10.009
    • (2012) Behav. Brain Res , vol.227 , pp. 497-507
    • Lee, S.W.1    Clemenson, G.D.2    Gage, F.H.3
  • 39
    • 77549087116 scopus 로고    scopus 로고
    • Functional cholinergic damage develops with amyloid accumulation in young adult APPswe/PS1dE9 transgenic mice
    • Machov�, E., Rudajev, V., Smyckov�, H., Koivisto, H., Tanila, H., and Dolezal, V. (2010). Functional cholinergic damage develops with amyloid accumulation in young adult APPswe/PS1dE9 transgenic mice. Neurobiol. Dis. 38, 27-35. doi: 10.1016/j.nbd.2009.12.023
    • (2010) Neurobiol. Dis , vol.38 , pp. 27-35
    • Machov�, E.1    Rudajev, V.2    Smyckov�, H.3    Koivisto, H.4    Tanila, H.5    Dolezal, V.6
  • 40
    • 0023119044 scopus 로고
    • An immunocytochemical study of choline acetyltransferase-containing neurons and axon terminals in normal and partially deafferented hippocampal formation
    • Matthews, D. A., Salvaterra, P. M., Crawford, G. D., Houser, C. R., and Vaughn, J. E. (1987). An immunocytochemical study of choline acetyltransferase-containing neurons and axon terminals in normal and partially deafferented hippocampal formation. Brain Res. 402, 30-43. doi: 10.1016/0006-8993(87)91044-4
    • (1987) Brain Res , vol.402 , pp. 30-43
    • Matthews, D.A.1    Salvaterra, P.M.2    Crawford, G.D.3    Houser, C.R.4    Vaughn, J.E.5
  • 41
    • 84899621158 scopus 로고    scopus 로고
    • IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice
    • Mellott, T. J., Pender, S. M., Burke, R. M., Langley, E. A., and Blusztajn, J. K. (2014). IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. PLoS One 9:e94287. doi: 10.1371/journal.pone.0094287
    • (2014) PLoS One , vol.9
    • Mellott, T.J.1    Pender, S.M.2    Burke, R.M.3    Langley, E.A.4    Blusztajn, J.K.5
  • 42
    • 13844296729 scopus 로고    scopus 로고
    • Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning
    • Mohapel, P., Leanza, G., Kokaia, M., and Lindvall, O. (2005). Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning. Neurobiol. Aging 26, 939-946. doi: 10.1016/j.neurobiolaging.2004.07.015
    • (2005) Neurobiol. Aging , vol.26 , pp. 939-946
    • Mohapel, P.1    Leanza, G.2    Kokaia, M.3    Lindvall, O.4
  • 43
    • 55849111494 scopus 로고    scopus 로고
    • Cholinergic system during the progression of Alzheimer's disease: therapeutic implications
    • Mufson, E. J., Counts, S. E., Perez, S. E., and Ginsberg, S. D. (2008). Cholinergic system during the progression of Alzheimer's disease: therapeutic implications. Expert Rev. Neurother. 8, 1703-1718. doi: 10.1586/14737175.8.11.1703
    • (2008) Expert Rev. Neurother , vol.8 , pp. 1703-1718
    • Mufson, E.J.1    Counts, S.E.2    Perez, S.E.3    Ginsberg, S.D.4
  • 44
    • 84863780825 scopus 로고    scopus 로고
    • Overexpression of the vesicular acetylcholine transporter increased acetylcholine release in the hippocampus
    • Nagy, P. M., and Aubert, I. (2012). Overexpression of the vesicular acetylcholine transporter increased acetylcholine release in the hippocampus. Neuroscience 218, 1-11. doi: 10.1016/j.neuroscience.2012.05.047
    • (2012) Neuroscience , vol.218 , pp. 1-11
    • Nagy, P.M.1    Aubert, I.2
  • 45
    • 84893470167 scopus 로고    scopus 로고
    • B6eGFPChAT mice overexpressing the vesicular acetylcholine transporter exhibit spontaneous hypoactivity and enhanced exploration in novel environments
    • Nagy, P. M., and Aubert, I. (2013). B6eGFPChAT mice overexpressing the vesicular acetylcholine transporter exhibit spontaneous hypoactivity and enhanced exploration in novel environments. Brain Behav. 3, 367-383. doi: 10.1002/brb3.139
    • (2013) Brain Behav , vol.3 , pp. 367-383
    • Nagy, P.M.1    Aubert, I.2
  • 46
    • 84933180246 scopus 로고    scopus 로고
    • Overexpression of the vesicular acetylcholine transporter enhances dendritic complexity of adult-born hippocampal neurons and improves acquisition of spatial memory during aging
    • Nagy, P. M., and Aubert, I. (2015). Overexpression of the vesicular acetylcholine transporter enhances dendritic complexity of adult-born hippocampal neurons and improves acquisition of spatial memory during aging. Neurobiol. Aging 36, 1881-1889. doi: 10.1016/j.neurobiolaging.2015.02.021
    • (2015) Neurobiol. Aging , vol.36 , pp. 1881-1889
    • Nagy, P.M.1    Aubert, I.2
  • 47
    • 67649842352 scopus 로고    scopus 로고
    • Donepezil improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus
    • Narimatsu, N., Harada, N., Kurihara, H., Nakagata, N., Sobue, K., and Okajima, K. (2009). Donepezil improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus. J. Pharmacol. Exp. Ther. 330, 2-12. doi: 10.1124/jpet.108.147280
    • (2009) J. Pharmacol. Exp. Ther , vol.330 , pp. 2-12
    • Narimatsu, N.1    Harada, N.2    Kurihara, H.3    Nakagata, N.4    Sobue, K.5    Okajima, K.6
  • 48
    • 80052617736 scopus 로고    scopus 로고
    • Cholinergic axon length reduced by 300 meters in the brain of an Alzheimer mouse model
    • Nikolajsen, G. N., Jensen, M. S., and West, M. J. (2011). Cholinergic axon length reduced by 300 meters in the brain of an Alzheimer mouse model. Neurobiol. Aging 32, 1927-1931. doi: 10.1016/j.neurobiolaging.2011.05.006
    • (2011) Neurobiol. Aging , vol.32 , pp. 1927-1931
    • Nikolajsen, G.N.1    Jensen, M.S.2    West, M.J.3
  • 49
    • 0026521779 scopus 로고
    • Cholinergic neurons in the rat central nervous system demonstrated by in situ hybridization of choline acetyltransferase mRNA
    • Oh, J. D., Woolf, N. J., Roghani, A., Edwards, R. H., and Butcher, L. L. (1992). Cholinergic neurons in the rat central nervous system demonstrated by in situ hybridization of choline acetyltransferase mRNA. Neuroscience 47, 807-822. doi: 10.1016/0306-4522(92)90031-v
    • (1992) Neuroscience , vol.47 , pp. 807-822
    • Oh, J.D.1    Woolf, N.J.2    Roghani, A.3    Edwards, R.H.4    Butcher, L.L.5
  • 50
    • 33846616940 scopus 로고    scopus 로고
    • Reduction in CHT1-mediated choline uptake in primary neurons from presenilin-1 M146V mutant knock-in mice
    • Payette, D. J., Xie, J., and Guo, Q. (2007). Reduction in CHT1-mediated choline uptake in primary neurons from presenilin-1 M146V mutant knock-in mice. Brain Res. 1135, 12-21. doi: 10.1016/j.brainres.2006.12.005
    • (2007) Brain Res , vol.1135 , pp. 12-21
    • Payette, D.J.1    Xie, J.2    Guo, Q.3
  • 51
    • 34548810808 scopus 로고    scopus 로고
    • Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse
    • Perez, S. E., Dar, S., Ikonomovic, M. D., DeKosky, S. T., and Mufson, E. J. (2007). Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse. Neurobiol. Dis. 28, 3-15. doi: 10.1016/j.nbd.2007.06.015
    • (2007) Neurobiol. Dis , vol.28 , pp. 3-15
    • Perez, S.E.1    Dar, S.2    Ikonomovic, M.D.3    DeKosky, S.T.4    Mufson, E.J.5
  • 52
    • 79151484921 scopus 로고    scopus 로고
    • The effects of neonatal forebrain cholinergic lesion on adult hippocampal neurogenesis
    • Rennie, K., Fr�chette, M., and Pappas, B. A. (2011). The effects of neonatal forebrain cholinergic lesion on adult hippocampal neurogenesis. Brain Res. 1373, 79-90. doi: 10.1016/j.brainres.2010.11.091
    • (2011) Brain Res , vol.1373 , pp. 79-90
    • Rennie, K.1    Fr�chette, M.2    Pappas, B.A.3
  • 53
    • 0343554026 scopus 로고    scopus 로고
    • Distribution of the vesicular transporter for acetylcholine in the rat central nervous system
    • Roghani, A., Shirzadi, A., Butcher, L. L., and Edwards, R. H. (1998). Distribution of the vesicular transporter for acetylcholine in the rat central nervous system. Neuroscience 82, 1195-1212. doi: 10.1016/s0306-4522(97)00291-1
    • (1998) Neuroscience , vol.82 , pp. 1195-1212
    • Roghani, A.1    Shirzadi, A.2    Butcher, L.L.3    Edwards, R.H.4
  • 54
    • 0030608513 scopus 로고    scopus 로고
    • Differential distribution of the putative vesicular transporter for acetylcholine in the rat central nervous system
    • Roghani, A., Shirzadi, A., Kohan, S. A., Edwards, R. H., and Butcher, L. L. (1996). Differential distribution of the putative vesicular transporter for acetylcholine in the rat central nervous system. Mol. Brain Res. 43, 65-76. doi: 10.1016/s0169-328x(96)00145-3
    • (1996) Mol. Brain Res , vol.43 , pp. 65-76
    • Roghani, A.1    Shirzadi, A.2    Kohan, S.A.3    Edwards, R.H.4    Butcher, L.L.5
  • 55
    • 79551555006 scopus 로고    scopus 로고
    • Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis
    • Rossi, J., Balthasar, N., Olson, D., Scott, M., Berglund, E., Lee, C. E., et al. (2011). Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metab. 13, 195-204. doi: 10.1016/j.cmet.2011.01.010
    • (2011) Cell Metab , vol.13 , pp. 195-204
    • Rossi, J.1    Balthasar, N.2    Olson, D.3    Scott, M.4    Berglund, E.5    Lee, C.E.6
  • 56
    • 58149343632 scopus 로고    scopus 로고
    • Genetically-directed, cell type-specific sparse labeling for the analysis of neuronal morphology
    • Rotolo, T., Smallwood, P. M., Williams, J., and Nathans, J. (2008). Genetically-directed, cell type-specific sparse labeling for the analysis of neuronal morphology. PLoS One 3:e4099. doi: 10.1371/journal.pone.0004099
    • (2008) PLoS One , vol.3
    • Rotolo, T.1    Smallwood, P.M.2    Williams, J.3    Nathans, J.4
  • 57
    • 84879216808 scopus 로고    scopus 로고
    • Impact of aging brain circuits on cognition
    • Samson, R. D., and Barnes, C. A. (2013). Impact of aging brain circuits on cognition. Eur. J. Neurosci. 37, 1903-1915. doi: 10.1111/ejn.12183
    • (2013) Eur. J. Neurosci , vol.37 , pp. 1903-1915
    • Samson, R.D.1    Barnes, C.A.2
  • 58
    • 3543048639 scopus 로고    scopus 로고
    • Developmental origins of the age-related decline in cortical cholinergic function and associated cognitive abilities
    • Sarter, M., and Bruno, J. P. (2004). Developmental origins of the age-related decline in cortical cholinergic function and associated cognitive abilities. Neurobiol. Aging 25, 1127-1139. doi: 10.1016/j.neurobiolaging.2003.11.011
    • (2004) Neurobiol. Aging , vol.25 , pp. 1127-1139
    • Sarter, M.1    Bruno, J.P.2
  • 59
    • 20044383377 scopus 로고    scopus 로고
    • Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities
    • Savonenko, A., Xu, G. M., Melnikova, T., Morton, J. L., Gonzales, V., Wong, M. P., et al. (2005). Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities. Neurobiol. Dis. 18, 602-617. doi: 10.1016/j.nbd.2004.10.022
    • (2005) Neurobiol. Dis , vol.18 , pp. 602-617
    • Savonenko, A.1    Xu, G.M.2    Melnikova, T.3    Morton, J.L.4    Gonzales, V.5    Wong, M.P.6
  • 60
    • 17444446041 scopus 로고    scopus 로고
    • Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. I. Central nervous system
    • Sch�fer, M. K. H., Eiden, L. E., and Weihe, E. (1998). Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. I. Central nervous system. Neuroscience 84, 331-359. doi: 10.1016/s0306-4522(97)00516-2
    • (1998) Neuroscience , vol.84 , pp. 331-359
    • Sch�fer, M.K.H.1    Eiden, L.E.2    Weihe, E.3
  • 61
    • 38149028515 scopus 로고    scopus 로고
    • Purification and culture of nerve growth factor receptor (p75)-expressing basal forebrain cholinergic neurons
    • Schnitzler, A. C., Lopez-Coviella, I., and Blusztajn, J. K. (2008). Purification and culture of nerve growth factor receptor (p75)-expressing basal forebrain cholinergic neurons. Nat. Protoc. 3, 34-40. doi: 10.1038/nprot.2007.477
    • (2008) Nat. Protoc , vol.3 , pp. 34-40
    • Schnitzler, A.C.1    Lopez-Coviella, I.2    Blusztajn, J.K.3
  • 62
    • 77953806362 scopus 로고    scopus 로고
    • BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons
    • Schnitzler, A. C., Mellott, T. J., Lopez-Coviella, I., Tallini, Y. N., Kotlikoff, M. I., Follettie, M. T., et al. (2010). BMP9 (bone morphogenetic protein 9) induces NGF as an autocrine/paracrine cholinergic trophic factor in developing basal forebrain neurons. J. Neurosci. 30, 8221-8228. doi: 10.1523/jneurosci.5611-09.2010
    • (2010) J. Neurosci , vol.30 , pp. 8221-8228
    • Schnitzler, A.C.1    Mellott, T.J.2    Lopez-Coviella, I.3    Tallini, Y.N.4    Kotlikoff, M.I.5    Follettie, M.T.6
  • 63
    • 33845742356 scopus 로고    scopus 로고
    • BAC transgenic mice express enhanced green fluorescent protein in central and peripheral cholinergic neurons
    • Tallini, Y. N., Shui, B., Greene, K. S., Deng, K. Y., Doran, R., Fisher, P. J., et al. (2006). BAC transgenic mice express enhanced green fluorescent protein in central and peripheral cholinergic neurons. Physiol. Genomics 27, 391-397. doi: 10.1152/physiolgenomics.00092.2006
    • (2006) Physiol. Genomics , vol.27 , pp. 391-397
    • Tallini, Y.N.1    Shui, B.2    Greene, K.S.3    Deng, K.Y.4    Doran, R.5    Fisher, P.J.6
  • 64
    • 84903020411 scopus 로고    scopus 로고
    • Cholinergic modulation of hippocampal network function
    • Teles-Grilo Ruivo, L. M., and Mellor, J. R. (2013). Cholinergic modulation of hippocampal network function. Front. Synaptic Neurosci. 5:2. doi: 10.3389/fnsyn.2013.00002
    • (2013) Front. Synaptic Neurosci , vol.5 , pp. 2
    • Teles-Grilo Ruivo, L.M.1    Mellor, J.R.2
  • 65
    • 84897539406 scopus 로고    scopus 로고
    • Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond
    • Ting, J. T., and Feng, G. (2014). Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond. Front. Behav. Neurosci. 8:111. doi: 10.3389/fnbeh.2014.00111
    • (2014) Front. Behav. Neurosci , vol.8 , pp. 111
    • Ting, J.T.1    Feng, G.2
  • 67
    • 77649338178 scopus 로고    scopus 로고
    • Agonist-induced restoration of hippocampal neurogenesis and cognitive improvement in a model of cholinergic denervation
    • Van Kampen, J. M., and Eckman, C. B. (2010). Agonist-induced restoration of hippocampal neurogenesis and cognitive improvement in a model of cholinergic denervation. Neuropharmacology 58, 921-929. doi: 10.1016/j.neuropharm.2009.12.005
    • (2010) Neuropharmacology , vol.58 , pp. 921-929
    • Van Kampen, J.M.1    Eckman, C.B.2
  • 68
    • 84949661704 scopus 로고    scopus 로고
    • Editorial: brain cholinergic mechanisms
    • Vijayaraghavan, S., and Sharma, G. (2015). Editorial: brain cholinergic mechanisms. Front. Synaptic Neurosci. 7:14. doi: 10.3389/fnsyn.2015.00014
    • (2015) Front. Synaptic Neurosci , vol.7 , pp. 14
    • Vijayaraghavan, S.1    Sharma, G.2
  • 69
    • 34250644907 scopus 로고    scopus 로고
    • Functional characterization of intrinsic cholinergic interneurons in the cortex
    • von Engelhardt, J., Eliava, M., Meyer, A. H., Rozov, A., and Monyer, H. (2007). Functional characterization of intrinsic cholinergic interneurons in the cortex. J. Neurosci. 27, 5633-5642. doi: 10.1523/jneurosci.4647-06.2007
    • (2007) J. Neurosci , vol.27 , pp. 5633-5642
    • von Engelhardt, J.1    Eliava, M.2    Meyer, A.H.3    Rozov, A.4    Monyer, H.5
  • 70
    • 0021944259 scopus 로고
    • Cholinergic and non-cholinergic septohippocampal pathways
    • Wainer, B. H., Levey, A. I., Rye, D. B., Mesulam, M. M., and Mufson, E. J. (1985). Cholinergic and non-cholinergic septohippocampal pathways. Neurosci. Lett. 54, 45-52. doi: 10.1016/s0304-3940(85)80116-6
    • (1985) Neurosci. Lett , vol.54 , pp. 45-52
    • Wainer, B.H.1    Levey, A.I.2    Rye, D.B.3    Mesulam, M.M.4    Mufson, E.J.5
  • 71
    • 0020072221 scopus 로고
    • Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain
    • Whitehouse, P. J., Price, D. L., Struble, R. G., Clark, A. W., Coyle, J. T., and Delong, M. R. (1982). Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 215, 1237-1239. doi: 10.1126/science.7058341
    • (1982) Science , vol.215 , pp. 1237-1239
    • Whitehouse, P.J.1    Price, D.L.2    Struble, R.G.3    Clark, A.W.4    Coyle, J.T.5    Delong, M.R.6
  • 72
    • 84900479248 scopus 로고    scopus 로고
    • Complete morphologies of basal forebrain cholinergic neurons in the mouse
    • Wu, H., Williams, J., and Nathans, J. (2014). Complete morphologies of basal forebrain cholinergic neurons in the mouse. Elife 3:e02444. doi: 10.7554/elife.02444
    • (2014) Elife , vol.3
    • Wu, H.1    Williams, J.2    Nathans, J.3
  • 73
    • 84942376390 scopus 로고    scopus 로고
    • Hippocampal "cholinergic interneurons" visualized with the choline acetyltransferase promoter: anatomical distribution, intrinsic membrane properties, neurochemical characteristics and capacity for cholinergic modulation
    • Yi, F., Catudio-Garrett, E., G�briel, R., Wilhelm, M., Erdelyi, F., Szabo, G., et al. (2015). Hippocampal "cholinergic interneurons" visualized with the choline acetyltransferase promoter: anatomical distribution, intrinsic membrane properties, neurochemical characteristics and capacity for cholinergic modulation. Front. Synaptic Neurosci. 7:4. doi: 10.3389/fnsyn.2015.00004
    • (2015) Front. Synaptic Neurosci , vol.7 , pp. 4
    • Yi, F.1    Catudio-Garrett, E.2    G�briel, R.3    Wilhelm, M.4    Erdelyi, F.5    Szabo, G.6
  • 74
    • 80052282876 scopus 로고    scopus 로고
    • Cell type-specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function
    • Zhao, S., Ting, J. T., Atallah, H. E., Qiu, L., Tan, J., Gloss, B., et al. (2011). Cell type-specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function. Nat. Methods 8, 745-752. doi: 10.1038/nmeth.1668
    • (2011) Nat. Methods , vol.8 , pp. 745-752
    • Zhao, S.1    Ting, J.T.2    Atallah, H.E.3    Qiu, L.4    Tan, J.5    Gloss, B.6
  • 75
    • 38149092393 scopus 로고    scopus 로고
    • Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage
    • Zhao, N., Zhong, C., Wang, Y., Zhao, Y., Gong, N., Zhou, G., et al. (2008). Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stage. Neurobiol. Dis. 29, 176-185. doi: 10.1016/j.nbd.2007.08.014
    • (2008) Neurobiol. Dis , vol.29 , pp. 176-185
    • Zhao, N.1    Zhong, C.2    Wang, Y.3    Zhao, Y.4    Gong, N.5    Zhou, G.6


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