Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae

mBio

Volumn 5, Issue 1, 2014, Pages

  Mellroth, Peter ^a   Sandalova, Tatyana ^b   Kikhney, Alexey ^c   Vilaplana, Francisco ^d   Hesek, Dusan ^e   Lee, Mijoon ^e   Mobashery, Shahriar ^b   Normark, Staffan ^a   Svergun, Dmitri ^c   Henriques Normark, Birgitta ^a,b   Achour, Adnane ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d ALBANOVA UNIVERSITY CENTER   (Sweden)

^e UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDASE; DIMER; PEPTIDOGLYCAN; PROTEIN LYTA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL WALL; CARBOHYDRATE SYNTHESIS; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; STREPTOCOCCUS PNEUMONIAE;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DNA MUTATIONAL ANALYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; PEPTIDOGLYCAN; PROTEIN BINDING; PROTEIN CONFORMATION; STREPTOCOCCUS PNEUMONIAE;

EID: 84903370963     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01120-13     Document Type: Article

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