RNA Nanoparticle-Based Targeted Therapy for Glioblastoma through Inhibition of Oncogenic miR-21

Molecular Therapy

Volumn 25, Issue 7, 2017, Pages 1544-1555

  Lee, Tae Jin ^a   Yoo, Ji Young ^a   Shu, Dan ^b,c   Li, Hui ^b,c   Zhang, Jianying ^a   Yu, Jun Ge ^d   Jaime Ramirez, Alena Cristina ^a   Acunzo, Mario ^a   Romano, Giulia ^a   Cui, Ri ^a   Sun, Hui Lung ^a   Luo, Zhenghua ^a   Old, Matthew ^d   Kaur, Balveen ^a   Guo, Peixuan ^b,c   Croce, Carlo M ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

Author keywords

3WJ; apoptosis; glioblastoma; microRNA; RNA nanoparticle

Indexed keywords

FOLIC ACID; MICRORNA 21; NANOCARRIER; PDCD4 PROTEIN; RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; ANTAGOMIR; APOPTOSIS REGULATORY PROTEIN; DRUG CARRIER; FOLATE RECEPTOR; LOCKED NUCLEIC ACID; MICRORNA; MIRN21 MICRORNA, HUMAN; NANOPARTICLE; OLIGONUCLEOTIDE; PDCD4 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN PROTEIN, HUMAN; RNA BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BACTERIOPHAGE; CANCER INHIBITION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE SILENCING; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OVERALL SURVIVAL; RNA SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; CHEMISTRY; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MORTALITY; NUDE MOUSE; PATHOLOGY; SURVIVAL ANALYSIS; TUMOR CELL LINE;

ANIMALS; ANTAGOMIRS; APOPTOSIS REGULATORY PROTEINS; BRAIN NEOPLASMS; CELL LINE, TUMOR; DRUG CARRIERS; FEMALE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; MICE; MICE, NUDE; MICRORNAS; NANOPARTICLES; OLIGONUCLEOTIDES; PTEN PHOSPHOHYDROLASE; RNA-BINDING PROTEINS; SURVIVAL ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85021814028     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1016/j.ymthe.2016.11.016     Document Type: Article

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