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Volumn 9, Issue 2, 2017, Pages 587-599

MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons

Author keywords

dopamine neurons; iPSC; MAPT; Parkinson's disease; tau

Indexed keywords

BETA III TUBULIN; BETA TUBULIN; DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; SHORT HAIRPIN RNA; TAU PROTEIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; ISOPROTEIN; MAPT PROTEIN, HUMAN;

EID: 85021793016     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2017.06.005     Document Type: Article
Times cited : (41)

References (37)
  • 2
    • 0026488111 scopus 로고
    • Structure and novel exons of the human tau gene
    • Andreadis, A., Brown, W.M., Kosik, K.S., Structure and novel exons of the human tau gene. Biochemistry 31 (1992), 10626–10633.
    • (1992) Biochemistry , vol.31 , pp. 10626-10633
    • Andreadis, A.1    Brown, W.M.2    Kosik, K.S.3
  • 3
    • 0035146717 scopus 로고    scopus 로고
    • Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy
    • Arai, T., Ikeda, K., Akiyama, H., Shikamoto, Y., Tsuchiya, K., Yagishita, S., Beach, T., Rogers, J., Schwab, C., McGeer, P.L., Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy. Acta Neuropathol. 101 (2001), 167–173.
    • (2001) Acta Neuropathol. , vol.101 , pp. 167-173
    • Arai, T.1    Ikeda, K.2    Akiyama, H.3    Shikamoto, Y.4    Tsuchiya, K.5    Yagishita, S.6    Beach, T.7    Rogers, J.8    Schwab, C.9    McGeer, P.L.10
  • 6
    • 53849146387 scopus 로고    scopus 로고
    • Haplotype-specific expression of the N-terminal exons 2 and 3 at the human MAPT locus
    • Caffrey, T.M., Joachim, C., Wade-Martins, R., Haplotype-specific expression of the N-terminal exons 2 and 3 at the human MAPT locus. Neurobiol. Aging 29 (2008), 1923–1929.
    • (2008) Neurobiol. Aging , vol.29 , pp. 1923-1929
    • Caffrey, T.M.1    Joachim, C.2    Wade-Martins, R.3
  • 8
    • 84982803301 scopus 로고    scopus 로고
    • C9orf72 hexanucleotide expansions are associated with altered endoplasmic reticulum calcium homeostasis and stress granule formation in induced pluripotent stem cell-derived neurons from patients with amyotrophic lateral sclerosis and frontotemporal dementia
    • Dafinca, R., Scaber, J., Ababneh, N., Lalic, T., Weir, G., Christian, H., Vowles, J., Douglas, A.G., Fletcher-Jones, A., Browne, C., et al. C9orf72 hexanucleotide expansions are associated with altered endoplasmic reticulum calcium homeostasis and stress granule formation in induced pluripotent stem cell-derived neurons from patients with amyotrophic lateral sclerosis and frontotemporal dementia. Stem Cells 34 (2016), 2063–2078.
    • (2016) Stem Cells , vol.34 , pp. 2063-2078
    • Dafinca, R.1    Scaber, J.2    Ababneh, N.3    Lalic, T.4    Weir, G.5    Christian, H.6    Vowles, J.7    Douglas, A.G.8    Fletcher-Jones, A.9    Browne, C.10
  • 10
    • 39749165656 scopus 로고    scopus 로고
    • Differential regulation of dynein and kinesin motor proteins by tau
    • Dixit, R., Ross, J.L., Goldman, Y.E., Holzbaur, E.L., Differential regulation of dynein and kinesin motor proteins by tau. Science 319 (2008), 1086–1089.
    • (2008) Science , vol.319 , pp. 1086-1089
    • Dixit, R.1    Ross, J.L.2    Goldman, Y.E.3    Holzbaur, E.L.4
  • 13
    • 0024745894 scopus 로고
    • Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
    • Goedert, M., Spillantini, M.G., Jakes, R., Rutherford, D., Crowther, R.A., Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3 (1989), 519–526.
    • (1989) Neuron , vol.3 , pp. 519-526
    • Goedert, M.1    Spillantini, M.G.2    Jakes, R.3    Rutherford, D.4    Crowther, R.A.5
  • 19
    • 33747739192 scopus 로고    scopus 로고
    • RBM4 interacts with an intronic element and stimulates tau exon 10 inclusion
    • Kar, A., Havlioglu, N., Tarn, W.Y., Wu, J.Y., RBM4 interacts with an intronic element and stimulates tau exon 10 inclusion. J. Biol. Chem. 281 (2006), 24479–24488.
    • (2006) J. Biol. Chem. , vol.281 , pp. 24479-24488
    • Kar, A.1    Havlioglu, N.2    Tarn, W.Y.3    Wu, J.Y.4
  • 26
    • 84857687714 scopus 로고    scopus 로고
    • SpliceAid 2: a database of human splicing factors expression data and RNA target motifs
    • Piva, F., Giulietti, M., Burini, A.B., Principato, G., SpliceAid 2: a database of human splicing factors expression data and RNA target motifs. Hum. Mutat. 33 (2012), 81–85.
    • (2012) Hum. Mutat. , vol.33 , pp. 81-85
    • Piva, F.1    Giulietti, M.2    Burini, A.B.3    Principato, G.4
  • 27
    • 85013170355 scopus 로고    scopus 로고
    • Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease
    • Sandor, C., Robertson, P., Lang, C., Heger, A., Booth, H., Vowles, J., Witty, L., Bowden, R., Hu, M., Cowley, S.A., et al. Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease. Hum. Mol. Genet. 26 (2017), 552–566.
    • (2017) Hum. Mol. Genet. , vol.26 , pp. 552-566
    • Sandor, C.1    Robertson, P.2    Lang, C.3    Heger, A.4    Booth, H.5    Vowles, J.6    Witty, L.7    Bowden, R.8    Hu, M.9    Cowley, S.A.10
  • 28
    • 0030748399 scopus 로고    scopus 로고
    • Different distribution of phosphorylated tau protein isoforms in Alzheimer's and Pick's diseases
    • Sergeant, N., David, J.P., Lefranc, D., Vermersch, P., Wattez, A., Delacourte, A., Different distribution of phosphorylated tau protein isoforms in Alzheimer's and Pick's diseases. FEBS Lett. 412 (1997), 578–582.
    • (1997) FEBS Lett. , vol.412 , pp. 578-582
    • Sergeant, N.1    David, J.P.2    Lefranc, D.3    Vermersch, P.4    Wattez, A.5    Delacourte, A.6
  • 30
    • 84990061214 scopus 로고    scopus 로고
    • Human iPSC-derived neuronal model of tau-A152T frontotemporal dementia reveals tau-mediated mechanisms of neuronal vulnerability
    • Silva, M.C., Cheng, C., Mair, W., Almeida, S., Fong, H., Biswas, M.H., Zhang, Z., Huang, Y., Temple, S., Coppola, G., et al. Human iPSC-derived neuronal model of tau-A152T frontotemporal dementia reveals tau-mediated mechanisms of neuronal vulnerability. Stem Cell Reports 7 (2016), 325–340.
    • (2016) Stem Cell Reports , vol.7 , pp. 325-340
    • Silva, M.C.1    Cheng, C.2    Mair, W.3    Almeida, S.4    Fong, H.5    Biswas, M.H.6    Zhang, Z.7    Huang, Y.8    Temple, S.9    Coppola, G.10
  • 32
    • 84940664560 scopus 로고    scopus 로고
    • Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT
    • Sposito, T., Preza, E., Mahoney, C.J., Seto-Salvia, N., Ryan, N.S., Morris, H.R., Arber, C., Devine, M.J., Houlden, H., Warner, T.T., et al. Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT. Hum. Mol. Genet. 24 (2015), 5260–5269.
    • (2015) Hum. Mol. Genet. , vol.24 , pp. 5260-5269
    • Sposito, T.1    Preza, E.2    Mahoney, C.J.3    Seto-Salvia, N.4    Ryan, N.S.5    Morris, H.R.6    Arber, C.7    Devine, M.J.8    Houlden, H.9    Warner, T.T.10
  • 36
    • 1442348429 scopus 로고    scopus 로고
    • Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors
    • Wang, J., Gao, Q.S., Wang, Y., Lafyatis, R., Stamm, S., Andreadis, A., Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. J. Neurochem. 88 (2004), 1078–1090.
    • (2004) J. Neurochem. , vol.88 , pp. 1078-1090
    • Wang, J.1    Gao, Q.S.2    Wang, Y.3    Lafyatis, R.4    Stamm, S.5    Andreadis, A.6
  • 37
    • 33748372746 scopus 로고    scopus 로고
    • Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau
    • Williams, D.R., Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule-associated protein tau. Intern. Med. J. 36 (2006), 652–660.
    • (2006) Intern. Med. J. , vol.36 , pp. 652-660
    • Williams, D.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.