Knockdown of frizzled-7 inhibits cell growth and metastasis and promotes chemosensitivity of esophageal squamous cell carcinoma cells by inhibiting Wnt signaling

Biochemical and Biophysical Research Communications

Volumn 490, Issue 3, 2017, Pages 1112-1118

  Liu, Xiaoping ^a   Yan, Yanli ^a   Ma, Weiping ^a   Wu, Suge ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Drug resistance; Esophageal squamous cell carcinoma; FZD7; Wnt

Indexed keywords

CISPLATIN; FRIZZLED 7 PROTEIN; FRIZZLED PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; FZD7 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL GROWTH; CELL INVASION; CELL MIGRATION; CHEMOSENSITIVITY; CONTROLLED STUDY; ESOPHAGEAL CANCER CELL LINE; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WNT SIGNALING PATHWAY; CARCINOMA, SQUAMOUS CELL; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; DRUG RESISTANCE; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CISPLATIN; DRUG RESISTANCE, NEOPLASM; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; P-GLYCOPROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; WNT SIGNALING PATHWAY;

EID: 85021785006     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.06.185     Document Type: Article

References (33)

1. Siegel, R.L., Miller, K.D., Jemal, A., Cancer statistics, 2016. CA Cancer J. Clin. 66 (2016), 7–30.
2. Fu, H.L., Wu, D.P., Wang, X.F., et al. Altered miRNA expression is associated with differentiation, invasion, and metastasis of esophageal squamous cell carcinoma (ESCC) in patients from Huaian, China. Cell Biochem. Biophys. 67 (2013), 657–668.
3. van Hagen, P., Hulshof, M.C., van Lanschot, J.J., et al. Preoperative chemoradiotherapy for esophageal or junctional cancer. N. Engl. J. Med. 366 (2012), 2074–2084.
4. Sanford, N.N., Catalano, P.J., Enzinger, P.C., et al. A retrospective comparison of neoadjuvant chemoradiotherapy regimens for locally advanced esophageal cancer. Dis. Esophagus 30 (2017), 1–8.
5. Takahashi, H., Arimura, Y., Yamashita, K., et al. Phase I/II study of docetaxel/cisplatin/fluorouracil combination chemotherapy against metastatic esophageal squamous cell carcinoma. J. Thorac. Oncol. 5 (2010), 122–128.
6. Miyata, H., Yoshioka, A., Yamasaki, M., et al. Tumor budding in tumor invasive front predicts prognosis and survival of patients with esophageal squamous cell carcinomas receiving neoadjuvant chemotherapy. Cancer 115 (2009), 3324–3334.
7. King, T.D., Zhang, W., Suto, M.J., et al. Frizzled7 as an emerging target for cancer therapy. Cell Signal 24 (2012), 846–851.
8. Sagara, N., Toda, G., Hirai, M., et al. Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7. Biochem. Biophys. Res. Commun. 252 (1998), 117–122.
9. Ueno, K., Hiura, M., Suehiro, Y., et al. Frizzled-7 as a potential therapeutic target in colorectal cancer. Neoplasia 10 (2008), 697–705.
10. Merle, P., de la Monte, S., Kim, M., et al. Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma. Gastroenterology 127 (2004), 1110–1122.
11. Kirikoshi, H., Sekihara, H., Katoh, M., Up-regulation of Frizzled-7 (FZD7) in human gastric cancer. Int. J. Oncol. 19 (2001), 111–115.
12. Yang, L., Wu, X., Wang, Y., et al. FZD7 has a critical role in cell proliferation in triple negative breast cancer. Oncogene 30 (2011), 4437–4446.
13. Deng, B., Zhang, S., Miao, Y., et al. Down-regulation of Frizzled-7 expression inhibits migration, invasion, and epithelial-mesenchymal transition of cervical cancer cell lines. Med. Oncol., 32, 2015, 102.
14. Qiu, X., Jiao, J., Li, Y., et al. Overexpression of FZD7 promotes glioma cell proliferation by upregulating TAZ. Oncotarget 7 (2016), 85987–85999.
15. Deng, B., Zhang, Y., Zhang, S., et al. MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7. Tumour Biol. 36 (2015), 8065–8073.
16. Wu, W., Dang, S., Feng, Q., et al. MicroRNA-542-3p inhibits the growth of hepatocellular carcinoma cells by targeting FZD7/Wnt signaling pathway. Biochem. Biophys. Res. Commun. 482 (2017), 100–105.
17. Chen, Z., Ma, T., Huang, C., et al. MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/beta-catenin pathway in hepatocellular carcinoma cells. Cell Signal 25 (2013), 2693–2701.
18. Wei, W., Chua, M.S., Grepper, S., et al. Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin. Mol. Cancer, 10, 2011, 16.
19. Liu, N., Zang, S., Liu, Y., et al. FZD7 regulates BMSCs-mediated protection of CML cells. Oncotarget 7 (2016), 6175–6187.
20. Phesse, T., Flanagan, D., Vincan, E., Frizzled7: a promising achilles' heel for targeting the Wnt receptor complex to treat cancer. Cancers (Basel), 8, 2016.
21. Moghbeli, M., Abbaszadegan, M.R., Golmakani, E., et al. Correlation of Wnt and NOTCH pathways in esophageal squamous cell carcinoma. J. Cell Commun. Signal 10 (2016), 129–135.
22. Wang, P., Li, L., Li, T., Positive correlation of cysteine-rich 61 and target genes of Wnt/beta-catenin pathway in esophageal squamous cell carcinoma. J. Cancer Res. Ther. 12 (2016), 19–22.
23. Ai, R., Sun, Y., Guo, Z., et al. NDRG1 overexpression promotes the progression of esophageal squamous cell carcinoma through modulating Wnt signaling pathway. Cancer Biol. Ther. 17 (2016), 943–954.
24. Zhang, J.X., Tong, Z.T., Yang, L., et al. PITX2: a promising predictive biomarker of patients' prognosis and chemoradioresistance in esophageal squamous cell carcinoma. Int. J. Cancer 132 (2013), 2567–2577.
25. Su, H., Jin, X., Zhang, X., et al. FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R. J. Transl. Med., 13, 2015, 104.
26. Mealey, K.L., Fidel, J., P-glycoprotein mediated drug interactions in animals and humans with cancer. J. Vet. Intern Med. 29 (2015), 1–6.
27. Merle, P., Kim, M., Herrmann, M., et al. Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma. J. Hepatol. 43 (2005), 854–862.
28. Kim, M., Lee, H.C., Tsedensodnom, O., et al. Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells. J. Hepatol. 48 (2008), 780–791.
29. Xu, H., Gong, L., Xia, Y., et al. Frizzled-7 promoter is highly active in tumors and promoter-driven Shiga-like toxin I inhibits hepatocellular carcinoma growth. Oncotarget 6 (2015), 39908–39923.
30. Ueno, K., Hazama, S., Mitomori, S., et al. Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells. Br. J. Cancer 101 (2009), 1374–1381.
31. Ren, W., Li, C., Duan, W., et al. MicroRNA-613 represses prostate cancer cell proliferation and invasion through targeting Frizzled7. Biochem. Biophys. Res. Commun. 469 (2016), 633–638.
32. Anastas, J.N., Kulikauskas, R.M., Tamir, T., et al. WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors. J. Clin. Invest 124 (2014), 2877–2890.
33. Li, X.X., Zheng, H.T., Peng, J.J., et al. RNA-seq reveals determinants for irinotecan sensitivity/resistance in colorectal cancer cell lines. Int. J. Clin. Exp. Pathol. 7 (2014), 2729–2736.