Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis

Development (Cambridge)

Volumn 144, Issue 13, 2017, Pages 2480-2489

  Firulli, Beth A ^a   Milliar, Hannah ^a   Toolan, Kevin P ^a   Harkin, Jade ^a   Fuchs, Robyn K ^b   Robling, Alex G ^a   Firulli, Anthony B ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

BHLH; Dimerization; Hand1; Limb development; Mouse; Transcription

Indexed keywords

ALX4 PROTEIN; HAND1 PROTEIN; IRX3 PROTIEN; IRX5 PROTIEN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI3; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CRE RECOMBINASE; HAND1 PROTEIN, MOUSE; HAND2 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; INTEGRASE; PRRX1 PROTEIN, MOUSE; SHH PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CONTROLLED STUDY; DIMERIZATION; EMBRYO; FEMALE; GAIN OF FUNCTION MUTATION; GENE CONTROL; GENE DOSAGE; LIMB BUD; LIMB DEVELOPMENT; LOSS OF FUNCTION MUTATION; MALE; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; ANIMAL; EMBRYOLOGY; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MESODERM; METABOLISM; MUTATION; PHENOTYPE; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ALLELES; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY PATTERNING; CELL DEATH; FEMALE; GENE DELETION; GENE DOSAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; INTEGRASES; LIMB BUDS; MALE; MESODERM; MICE; MORPHOGENESIS; MUTATION; PHENOTYPE; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 85021773847     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.149963     Document Type: Article

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