메뉴 건너뛰기




Volumn 2017, Issue 6, 2017, Pages

Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants

Author keywords

[No Author keywords available]

Indexed keywords

LACTOFERRIN; MALTODEXTRIN; PLACEBO; PROBIOTIC AGENT;

EID: 85021767712     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD007137.pub5     Document Type: Review
Times cited : (107)

References (68)
  • 1
    • 84929936500 scopus 로고    scopus 로고
    • Oral lactoferrin to prevent nosocomial sepsis and necrotizing enterocolitis of premature neonates and effect on T-regulatory cells
    • PUBMED: 24839144 2919955
    • Akin IM, Atasay B, Dogu F, Okulu E, Arsan S, Karatas HD, et al. Oral lactoferrin to prevent nosocomial sepsis and necrotizing enterocolitis of premature neonates and effect on T-regulatory cells. American Journal of Perinatology 2014;31(12):1111-20. [DOI: 10.1055/s-0034-1371704; PUBMED: 24839144]2919955
    • (2014) American Journal of Perinatology , vol.31 , Issue.12 , pp. 1111-1120
    • Akin, I.M.1    Atasay, B.2    Dogu, F.3    Okulu, E.4    Arsan, S.5    Karatas, H.D.6
  • 2
    • 84962016093 scopus 로고    scopus 로고
    • The Lacuna Trial: a double-blind randomized controlled pilot trial of lactoferrin supplementation in the very preterm infant
    • PUBMED: 26938920 5741111
    • Barrington KJ, Assaad MA, Janvier A. The Lacuna Trial: a double-blind randomized controlled pilot trial of lactoferrin supplementation in the very preterm infant. Journal of Perinatology 2016;36(8):666-9. [DOI: 10.1038/jp.2016.24; PUBMED: 26938920]5741111
    • (2016) Journal of Perinatology , vol.36 , Issue.8 , pp. 666-669
    • Barrington, K.J.1    Assaad, M.A.2    Janvier, A.3
  • 3
    • 84944066590 scopus 로고    scopus 로고
    • Efficacy of bovine lactoferrin supplementation in preventing late-onset sepsis in low birth weight neonates: a randomized placebo-controlled clinical trial
    • PUBMED: 26224129 5741113
    • Kaur G, Gathwala G. Efficacy of bovine lactoferrin supplementation in preventing late-onset sepsis in low birth weight neonates: a randomized placebo-controlled clinical trial. Journal of Tropical Pediatrics 2015;61(5):370-6. [DOI: 10.1093/tropej/fmv044; PUBMED: 26224129]5741113
    • (2015) Journal of Tropical Pediatrics , vol.61 , Issue.5 , pp. 370-376
    • Kaur, G.1    Gathwala, G.2
  • 4
    • 84897561629 scopus 로고    scopus 로고
    • Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: a randomized clinical trial
    • PUBMED: 24709463 2919961
    • Manzoni P, Meyer M, Stolfi I, Rinaldi M, Cattani S, Pugni L, et al. Bovine lactoferrin supplementation for prevention of necrotizing enterocolitis in very-low-birth-weight neonates: a randomized clinical trial. Early Human Development 2014;90 Suppl 1:S60-5. [DOI: 10.1016/S0378-3782(14)70020-9; PUBMED: 24709463]2919961
    • (2014) Early Human Development , vol.90 , pp. S60-S65
    • Manzoni, P.1    Meyer, M.2    Stolfi, I.3    Rinaldi, M.4    Cattani, S.5    Pugni, L.6
  • 5
    • 70349914008 scopus 로고    scopus 로고
    • Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: a randomized trial
    • PUBMED: PubMed: 19809023]]5741114
    • Manzoni P, Rinaldi M, Cattani S, Pugni L, Romeo MG, Messner H, et al. Italian Task Force for the Study and Prevention of Neonatal Fungal Infections, The Italian Society of Neonatology. Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: a randomized trial. JAMA 2009;302(13):1421-8. [PUBMED: DOI: 10.1001/jama.2009.1403; PubMed: 19809023]]5741114
    • (2009) JAMA , vol.302 , Issue.13 , pp. 1421-1428
    • Manzoni, P.1    Rinaldi, M.2    Cattani, S.3    Pugni, L.4    Romeo, M.G.5    Messner, H.6
  • 6
    • 84855281430 scopus 로고    scopus 로고
    • Bovine lactoferrin prevents invasive fungal infections in very low birth weight infants: a randomized controlled trial
    • PUBMED: PubMed: 22184648]]5741115
    • Manzoni P, Stolfi I, Messner H, Cattani S, Laforgia N, Romeo MG, et al. Italian Task Force for the Study and Prevention of Neonatal Fungal Infections, The Italian Society of Neonatology. Bovine lactoferrin prevents invasive fungal infections in very low birth weight infants: a randomized controlled trial. Pediatrics 2012;129(1):116-23. [PUBMED: DOI: 10.1542/peds.2011-0279; PubMed: 22184648]]5741115
    • (2012) Pediatrics , vol.129 , Issue.1 , pp. 116-123
    • Manzoni, P.1    Stolfi, I.2    Messner, H.3    Cattani, S.4    Laforgia, N.5    Romeo, M.G.6
  • 7
    • 84937712281 scopus 로고    scopus 로고
    • Randomized controlled trial of lactoferrin for prevention of sepsis in Peruvian neonates less than 2500 g
    • NCT01264536 2919963
    • Ochoa TJ, Zegarra J, Cam L, Llanos R, Pezo A, Cruz K, et al. NEOLACTO Research Group. Randomized controlled trial of lactoferrin for prevention of sepsis in Peruvian neonates less than 2500 g. Pediatric Infectious Disease Journal 2015;34(6):571-6. [DOI: 10.1097/INF.0000000000000593; NCT01264536]2919963
    • (2015) Pediatric Infectious Disease Journal , vol.34 , Issue.6 , pp. 571-576
    • Ochoa, T.J.1    Zegarra, J.2    Cam, L.3    Llanos, R.4    Pezo, A.5    Cruz, K.6
  • 8
    • 84973632318 scopus 로고    scopus 로고
    • Randomized controlled trial of talactoferrin oral solution in preterm infants
    • 3360.7 2919965
    • Sherman MP, Adamkin DH, Niklas V, Radmacher P, Sherman J, Wertheimer F, et al. Randomized controlled trial of talactoferrin oral solution in preterm infants. Journal of Pediatrics 2016;175:68-73.e3. [DOI: 10.1016/j.jpeds.2016.04.084; 3360.7]2919965
    • (2016) Journal of Pediatrics , vol.175 , pp. 68-73e3
    • Sherman, M.P.1    Adamkin, D.H.2    Niklas, V.3    Radmacher, P.4    Sherman, J.5    Wertheimer, F.6
  • 9
    • 33846598908 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, pilot study of bovine lactoferrin supplementation in bottle-fed infants
    • PUBMED: 17255839 2919967
    • King JC Jr, Cummings GE, Guo N, Trivedi L, Readmond BX, Keane V, et al. A double-blind, placebo-controlled, pilot study of bovine lactoferrin supplementation in bottle-fed infants. Journal of Pediatric Gastroenterology and Nutrition 2007;44(2):245-51. [DOI: 10.1097/01.mpg.0000243435.54958.68; PUBMED: 17255839]2919967
    • (2007) Journal of Pediatric Gastroenterology and Nutrition , vol.44 , Issue.2 , pp. 245-251
    • King, J.C.1    Cummings, G.E.2    Guo, N.3    Trivedi, L.4    Readmond, B.X.5    Keane, V.6
  • 10
    • 85021722938 scopus 로고    scopus 로고
    • Reduced rates of necrotizing enterocolitis following routine supplementation with Lactobacillus GG and lactoferrin: an observational study
    • Pediatric Academic Societies Meeting, May 16, 2016, Baltimore Convention Center. Baltimore, Maryland, E-PAS2016:4159.485]5741117
    • Meyer MP, Alexander T. Reduced rates of necrotizing enterocolitis following routine supplementation with Lactobacillus GG and lactoferrin: an observational study. Poster Session: Neonatology: Neonatal GI Physiology & NEC: Probiotics, Antibiotics and Microbiome. Pediatric Academic Societies Meeting, May 16, 2016, Baltimore Convention Center. Baltimore, Maryland, 2016. [E-PAS2016:4159.485]5741117
    • (2016) Poster Session: Neonatology: Neonatal GI Physiology & NEC: Probiotics, Antibiotics and Microbiome
    • Meyer, M.P.1    Alexander, T.2
  • 11
    • 84872292894 scopus 로고    scopus 로고
    • Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children
    • PUBMED: 22939927 2919969
    • Ochoa T, Chea-Woo E, Baiocchi N, Pecho I, Campos M, Prada A, et al. Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children. Journal of Pediatrics 2013;162(2):349-56. [DOI: 10.1016/j.jpeds.2012.07.043; PUBMED: 22939927]2919969
    • (2013) Journal of Pediatrics , vol.162 , Issue.2 , pp. 349-356
    • Ochoa, T.1    Chea-Woo, E.2    Baiocchi, N.3    Pecho, I.4    Campos, M.5    Prada, A.6
  • 12
    • 85021733819 scopus 로고    scopus 로고
    • Effect of prebiotic or lactoferrin supplementation in formula on the gut flora of preterm infants
    • (first received 05 September 2008) 2919975
    • ISRCTN71737811. Effect of prebiotic or lactoferrin supplementation in formula on the gut flora of preterm infants. www.controlled-trials.com/ISCRTN71737811 (first received 05 September 2008). [DOI: 10.1186/ISRCTN71737811]2919975
  • 13
    • 85021746902 scopus 로고    scopus 로고
    • Supplementation with lactoferrin in preterm newborns (lactoprenew)
    • (first received 28 July 2010). 2919973
    • NCT01172236. Supplementation with lactoferrin in preterm newborns (lactoprenew). clinicaltrials.gov/show/NCT01172236 (first received 28 July 2010). 2919973
  • 14
    • 85021702022 scopus 로고    scopus 로고
    • Early versus late lactoferrin in prevention of neonatal sepsis [Systematic randomized, single blinded, placebo-controlled trial of early versus late lactoferrin in prevention of neonatal sepsis]
    • (first received 27 October 2016). 5741119
    • NCT02959229. Early versus late lactoferrin in prevention of neonatal sepsis [Systematic randomized, single blinded, placebo-controlled trial of early versus late lactoferrin in prevention of neonatal sepsis]. clinicaltrials.gov/show/NCT02959229 (first received 27 October 2016). 5741119
  • 15
    • 85021778336 scopus 로고    scopus 로고
    • Lactoferrin infant feeding trial (LIFT) to prevent sepsis and death in preterm infants [Does lactoferrin improve survival free from morbidity in very low birth weight infants? Lactoferrin Infant Feeding Trial: a randomised controlled trial]
    • (first received 03 March 2011). 2919983
    • ACTRN12611000247976. Lactoferrin infant feeding trial (LIFT) to prevent sepsis and death in preterm infants [Does lactoferrin improve survival free from morbidity in very low birth weight infants? Lactoferrin Infant Feeding Trial: a randomised controlled trial]. www.anzctr.org.au/ACTRN12611000247976 (first received 03 March 2011). 2919983
  • 16
    • 85021703895 scopus 로고    scopus 로고
    • Enteral lactoferrin In neonates
    • (first received 05 June 2013) 2919979
    • ISRCTN88261002. Enteral lactoferrin In neonates. www.controlled-trials.com/ISRCTN88261002 (first received 05 June 2013). [DOI: 10.1186/ISRCTN88261002]2919979
  • 17
    • 85021767315 scopus 로고    scopus 로고
    • Lactoferrin for prevention of sepsis in infants (NEOLACTO)
    • (first received 30 January 2012). 2919981
    • NCT01525316. Lactoferrin for prevention of sepsis in infants (NEOLACTO). clinicaltrials.gov/show/NCT01525316 (first received 30 January 2012). 2919981
  • 18
    • 85021761173 scopus 로고    scopus 로고
    • Oral lactoferrin supplementation for prevention of sepsis in preterm neonate
    • (first received 27 March 2013). 2919977
    • NCT01821989. Oral lactoferrin supplementation for prevention of sepsis in preterm neonate. clinicaltrials.gov/show/NCT01821989 (first received 27 March 2013). 2919977
  • 19
    • 33646678434 scopus 로고    scopus 로고
    • Neonatal infection and long-term neurodevelopmental outcome in the preterm infant
    • PUBMED: 16645492
    • Adams-Chapman I, Stoll BJ. Neonatal infection and long-term neurodevelopmental outcome in the preterm infant. Current Opinion in Infectious Diseases 2006;19(3):290-7. [DOI: 10.1097/01.qco.0000224825.57976.87; PUBMED: 16645492]
    • (2006) Current Opinion in Infectious Diseases , vol.19 , Issue.3 , pp. 290-297
    • Adams-Chapman, I.1    Stoll, B.J.2
  • 20
    • 84942743424 scopus 로고    scopus 로고
    • Probiotics for prevention of necrotizing enterocolitis in preterm infants
    • AlFaleh K, Anabrees J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2014, Issue 4. [DOI: 10.1002/14651858.CD005496.pub4]
    • (2014) Cochrane Database of Systematic Reviews , Issue.4
    • AlFaleh, K.1    Anabrees, J.2
  • 21
    • 3142608843 scopus 로고    scopus 로고
    • Enhanced clearance of Escherichia coli and Staphylococcus aureus in mice treated with cyclophosphamide and lactoferrin
    • PUBMED: 15251111
    • Artym J, Zimecki M, Kruzel ML. Enhanced clearance of Escherichia coli and Staphylococcus aureus in mice treated with cyclophosphamide and lactoferrin. International Immunopharmacology 2004;4(9):1149-57. [DOI: 10.1016/j.intimp.2004.05.002; PUBMED: 15251111]
    • (2004) International Immunopharmacology , vol.4 , Issue.9 , pp. 1149-1157
    • Artym, J.1    Zimecki, M.2    Kruzel, M.L.3
  • 22
    • 84862141706 scopus 로고    scopus 로고
    • Glycosylation of human milk lactoferrin exhibits dynamic changes during early lactation enhancing its role in pathogenic bacteria-host interactions
    • M111015248 PUBMED: 22261723
    • Barboza M, Pinzon J, Wickramasinghe S, Froehlich J, Moeller I, Smilowitz J, et al. Glycosylation of human milk lactoferrin exhibits dynamic changes during early lactation enhancing its role in pathogenic bacteria-host interactions. Molecular Cell Proteomics 2012;11(6):M111.015248. [DOI: 10.1074/mcp.M111.015248; PUBMED: 22261723]
    • (2012) Molecular Cell Proteomics , vol.11 , Issue.6
    • Barboza, M.1    Pinzon, J.2    Wickramasinghe, S.3    Froehlich, J.4    Moeller, I.5    Smilowitz, J.6
  • 23
    • 0017917048 scopus 로고
    • Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging
    • PUBMED: 413500]
    • Bell MJ, Ternberg JL, Feigin RD, Keating JP, Marshall R, Barton L, et al. Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Annals of Surgery 1978;187(1):1-7. [PUBMED: 413500]
    • (1978) Annals of Surgery , vol.187 , Issue.1 , pp. 1-7
    • Bell, M.J.1    Ternberg, J.L.2    Feigin, R.D.3    Keating, J.P.4    Marshall, R.5    Barton, L.6
  • 24
    • 0026475489 scopus 로고
    • Antibacterial spectrum of lactoferricin B, a potent bactericidal peptide derived from the N-terminal region of bovine lactoferrin
    • PUBMED: 1490908]
    • Bellamy W, Takase M, Wakabayashi H, Kawase K, Tomita M. Antibacterial spectrum of lactoferricin B, a potent bactericidal peptide derived from the N-terminal region of bovine lactoferrin. Journal of Applied Bacteriology 1992;73(6):472-9. [PUBMED: 1490908]
    • (1992) Journal of Applied Bacteriology , vol.73 , Issue.6 , pp. 472-479
    • Bellamy, W.1    Takase, M.2    Wakabayashi, H.3    Kawase, K.4    Tomita, M.5
  • 26
    • 34147147026 scopus 로고    scopus 로고
    • Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation
    • PUBMED: 17515863
    • Buccigrossi V, de Marco G, Bruzzese E, Ombrato L, Bracale I, Polito G, et al. Lactoferrin induces concentration-dependent functional modulation of intestinal proliferation and differentiation. Pediatric Research 2007;61(4):410-4. [DOI: 10.1203/pdr.0b013e3180332c8d; PUBMED: 17515863]
    • (2007) Pediatric Research , vol.61 , Issue.4 , pp. 410-414
    • Buccigrossi, V.1    de Marco, G.2    Bruzzese, E.3    Ombrato, L.4    Bracale, I.5    Polito, G.6
  • 27
    • 85011798221 scopus 로고    scopus 로고
    • Prebiotic effects of bovine lactoferrin on specific probiotic bacteria
    • Chen PW, Liu ZS, Kuo TC, Hsieh MC, Li ZW. Prebiotic effects of bovine lactoferrin on specific probiotic bacteria. Biometals 2017;30(2):237-48.
    • (2017) Biometals , vol.30 , Issue.2 , pp. 237-248
    • Chen, P.W.1    Liu, Z.S.2    Kuo, T.C.3    Hsieh, M.C.4    Li, Z.W.5
  • 28
    • 85013059552 scopus 로고    scopus 로고
    • The "golden age" of probiotics: a systematic review and meta-analysis of randomized and observational studies in preterm infants
    • Dermyshi E, Wang Y, Yan C, Hong W, Qiu G, Gong X, Zhang T. The "golden age" of probiotics: a systematic review and meta-analysis of randomized and observational studies in preterm infants. Neonatology 2017;112(1):9-23.
    • (2017) Neonatology , vol.112 , Issue.1 , pp. 9-23
    • Dermyshi, E.1    Wang, Y.2    Yan, C.3    Hong, W.4    Qiu, G.5    Gong, X.6    Zhang, T.7
  • 30
    • 28344438950 scopus 로고    scopus 로고
    • Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties
    • PUBMED: 16261252
    • Gifford JL, Hunter HN, Vogel HJ. Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties. Cellular and Molecular Life Sciences 2005;62(22):2588-98. [DOI: 10.1007/s00018-005-5373-z; PUBMED: 16261252]
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2588-2598
    • Gifford, J.L.1    Hunter, H.N.2    Vogel, H.J.3
  • 31
    • 84963723096 scopus 로고    scopus 로고
    • GRADEpro GDT
    • Version accessed 09 March 2017. Hamilton (ON): GRADE Working Group, McMaster University,
    • GRADE Working Group, McMaster University. GRADEpro GDT. Version accessed 09 March 2017. Hamilton (ON): GRADE Working Group, McMaster University, 2014.
    • (2014)
  • 32
    • 43049113533 scopus 로고    scopus 로고
    • GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    • PUBMED: 18436948
    • Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008;336(7650):924-6. [DOI: 10.1136/bmj.39489.470347.AD; PUBMED: 18436948]
    • (2008) BMJ , vol.336 , Issue.7650 , pp. 924-926
    • Guyatt, G.H.1    Oxman, A.D.2    Vist, G.E.3    Kunz, R.4    Falck-Ytter, Y.5    Alonso-Coello, P.6
  • 34
    • 84887346660 scopus 로고    scopus 로고
    • Cochrane Handbook for Systematic Reviews of Interventions
    • Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011 The Cochrane Collaboration
    • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. handbook.cochrane.org. The Cochrane Collaboration. Available from www.cochrane-handbook.org.
    • Higgins, J.P.T.1    Green, S.2
  • 35
    • 0036127867 scopus 로고    scopus 로고
    • Lactoferrin inhibits hepatitis C virus viremia in chronic hepatitis C patients with high viral loads and HCV genotype 1b
    • PUBMED: 11922584
    • Iwasa M, Kaito M, Ikoma J, Takeo M, Imoto I, Yamauchi K, et al. Lactoferrin inhibits hepatitis C virus viremia in chronic hepatitis C patients with high viral loads and HCV genotype 1b. American Journal of Gastroenterology 2002;97(3):766-7. [DOI: 10.1111/j.1572-0241.2002.05573.x; PUBMED: 11922584]
    • (2002) American Journal of Gastroenterology , vol.97 , Issue.3 , pp. 766-767
    • Iwasa, M.1    Kaito, M.2    Ikoma, J.3    Takeo, M.4    Imoto, I.5    Yamauchi, K.6
  • 36
    • 0032707616 scopus 로고    scopus 로고
    • Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates
    • PUBMED: 10543740]
    • Kuipers ME, de Vries HG, Eikelboom MC, Meijer DK, Swart PJ. Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates. Antimicrobial Agents and Chemotherapy 1999;43(11):2635-41. [PUBMED: 10543740]
    • (1999) Antimicrobial Agents and Chemotherapy , vol.43 , Issue.11 , pp. 2635-2641
    • Kuipers, M.E.1    de Vries, H.G.2    Eikelboom, M.C.3    Meijer, D.K.4    Swart, P.J.5
  • 37
    • 33646471734 scopus 로고    scopus 로고
    • Estimating the causes of 4 million neonatal deaths in the year 2000
    • PUBMED: 16556647
    • Lawn JE, Wilczynska-Ketende K, Cousens SN. Estimating the causes of 4 million neonatal deaths in the year 2000. International Journal of Epidemiology 2006;35(3):706-18. [DOI: 10.1093/ije/dyl043; PUBMED: 16556647]
    • (2006) International Journal of Epidemiology , vol.35 , Issue.3 , pp. 706-718
    • Lawn, J.E.1    Wilczynska-Ketende, K.2    Cousens, S.N.3
  • 38
    • 84970004115 scopus 로고    scopus 로고
    • Overview of lactoferrin as a natural immune modulator
    • Legrand D. Overview of lactoferrin as a natural immune modulator. Journal of Pediatrics 2016;173(Suppl):S10-5. [DOI: 10.1016/j.jpeds.2016.02.071]
    • (2016) Journal of Pediatrics , vol.173 , pp. S10-S15
    • Legrand, D.1
  • 39
    • 0032991901 scopus 로고    scopus 로고
    • Lactoferrin increases the susceptibility of S. epidermidis biofilms to lysozyme and vancomycin
    • [PUBMED: 10415452]
    • Leitch EC, Willcox MD. Lactoferrin increases the susceptibility of S. epidermidis biofilms to lysozyme and vancomycin. Current Eye Research 1999;19(1):12-9. [PUBMED: 10415452]
    • (1999) Current Eye Research , vol.19 , Issue.1 , pp. 12-19
    • Leitch, E.C.1    Willcox, M.D.2
  • 40
    • 0032486989 scopus 로고    scopus 로고
    • Antimicrobial resistance: bacteria on the defence. Resistance stems from misguided efforts to try to sterilize our environment
    • [PUBMED: 9727983]
    • Levy SB. Antimicrobial resistance: bacteria on the defence. Resistance stems from misguided efforts to try to sterilize our environment. BMJ 1998;317(7159):612-3. [PUBMED: 9727983]
    • (1998) BMJ , vol.317 , Issue.7159 , pp. 612-613
    • Levy, S.B.1
  • 41
    • 33749256460 scopus 로고    scopus 로고
    • Necrotizing enterocolitis
    • PUBMED: 17027734
    • Lin PW, Stoll BJ. Necrotizing enterocolitis. Lancet 2006;368(9543):1271-83. [DOI: 10.1016/S0140-6736(06)69525-1; PUBMED: 17027734]
    • (2006) Lancet , vol.368 , Issue.9543 , pp. 1271-1283
    • Lin, P.W.1    Stoll, B.J.2
  • 42
    • 84880854801 scopus 로고    scopus 로고
    • Lactoferrin and the newborn: current perspectives
    • PUBMED: 23879609
    • Lingappan K, Arunachalam A, Pammi M. Lactoferrin and the newborn: current perspectives. Expert Reviews of Anti-Infective Therapy 2013;11(7):695-707. [DOI: 10.1586/14787210.2013.811927; PUBMED: 23879609]
    • (2013) Expert Reviews of Anti-Infective Therapy , vol.11 , Issue.7 , pp. 695-707
    • Lingappan, K.1    Arunachalam, A.2    Pammi, M.3
  • 43
    • 84969920049 scopus 로고    scopus 로고
    • Clinical benefits of lactoferrin for infants and children
    • PUBMED: 27234411
    • Manzoni P. Clinical benefits of lactoferrin for infants and children. Journal of Pediatrics 2016;173(Suppl):S43-52. [DOI: 10.1016/j.jpeds.2016.02.075; PUBMED: 27234411]
    • (2016) Journal of Pediatrics , vol.173 , pp. S43-S52
    • Manzoni, P.1
  • 44
    • 1542410492 scopus 로고    scopus 로고
    • Molecular aspects of intestinal epithelial cell-bacterial interactions that determine the development of intestinal inflammation
    • [PUBMED: 15168817]
    • Neish AS. Molecular aspects of intestinal epithelial cell-bacterial interactions that determine the development of intestinal inflammation. Inflammatory Bowel Diseases 2004;10(2):159-68. [PUBMED: 15168817]
    • (2004) Inflammatory Bowel Diseases , vol.10 , Issue.2 , pp. 159-168
    • Neish, A.S.1
  • 45
    • 0035112330 scopus 로고    scopus 로고
    • Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria
    • PUBMED: 11179314
    • Nibbering PH, Ravensbergen E, Welling MM, van Berkel LA, van Berkel PH, Pauwels EK, et al. Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria. Infection and Immunity 2001;69(3):1469-76. [DOI: 10.1128/IAI.69.3.1469-1476.2001; PUBMED: 11179314]
    • (2001) Infection and Immunity , vol.69 , Issue.3 , pp. 1469-1476
    • Nibbering, P.H.1    Ravensbergen, E.2    Welling, M.M.3    van Berkel, L.A.4    van Berkel, P.H.5    Pauwels, E.K.6
  • 46
    • 85012240376 scopus 로고    scopus 로고
    • Lactoferrin and prematurity: a promising milk protein?
    • Ochoa TJ, Sizonenko SV. Lactoferrin and prematurity: a promising milk protein?. Biochemistry and Cell Biology 2017;95(1):22-30. [DOI: 10.1139/bcb-2016-0066]
    • (2017) Biochemistry and Cell Biology , vol.95 , Issue.1 , pp. 22-30
    • Ochoa, T.J.1    Sizonenko, S.V.2
  • 48
    • 84986221380 scopus 로고    scopus 로고
    • Review Manager 5 (RevMan 5)
    • Version 5.3. Copenhagen: Nordic Cochrane Centre, The Cochrane Collaboration,
    • Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager 5 (RevMan 5). Version 5.3. Copenhagen: Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
    • (2014)
  • 49
    • 70350275459 scopus 로고    scopus 로고
    • GRADE Handbook for Grading Quality of Evidence and Strength of Recommendations
    • editors. [Updated October 2013]
    • Schünemann H, Brozek J, Guyatt G, Oxman A, editors. GRADE Working Group. GRADE Handbook for Grading Quality of Evidence and Strength of Recommendations. https://gdt.gradepro.org/app/handbook/handbook.html [Updated October 2013].
    • Schünemann, H.1    Brozek, J.2    Guyatt, G.3    Oxman, A.4
  • 50
    • 0032745094 scopus 로고    scopus 로고
    • Inflammatory mechanisms in neonatal chronic lung disease
    • [PUBMED: 10592094]
    • Speer CP. Inflammatory mechanisms in neonatal chronic lung disease. European Journal of Pediatrics 1999;158(Suppl 1):S18-22. [PUBMED: 10592094]
    • (1999) European Journal of Pediatrics , vol.158 , pp. S18-S22
    • Speer, C.P.1
  • 51
    • 18444388276 scopus 로고    scopus 로고
    • Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network
    • PUBMED: 12165580]
    • Stoll BJ, Hansen N, Fanaroff AA, Wright LL, Carlo WA, Ehrenkranz RA, et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 2002;110(2 Pt 1):285-91. [PUBMED: 12165580]
    • (2002) Pediatrics , vol.110 , Issue.2 PART. 1 , pp. 285-291
    • Stoll, B.J.1    Hansen, N.2    Fanaroff, A.A.3    Wright, L.L.4    Carlo, W.A.5    Ehrenkranz, R.A.6
  • 52
    • 8544252449 scopus 로고    scopus 로고
    • Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection
    • PUBMED: 15547163
    • Stoll BJ, Hansen NI, Adams-Chapman I, Fanaroff AA, Hintz SR, Vohr B, et al. National Institute of Child Health and Human Development Neonatal Research Network. Neurodevelopmental and growth impairment among extremely low-birth-weight infants with neonatal infection. JAMA 2004;292(19):2357-65. [DOI: 10.1001/jama.292.19.2357; PUBMED: 15547163]
    • (2004) JAMA , vol.292 , Issue.19 , pp. 2357-2365
    • Stoll, B.J.1    Hansen, N.I.2    Adams-Chapman, I.3    Fanaroff, A.A.4    Hintz, S.R.5    Vohr, B.6
  • 53
    • 17744362226 scopus 로고    scopus 로고
    • Infections of the neonatal infant
    • In: Behrman RE, Kliegman R, Jenson HB editor(s). 17th Edition. Philadelphia: Saunders
    • Stoll BJ. Infections of the neonatal infant. In: Behrman RE, Kliegman R, Jenson HB editor(s). Nelson's Textbook of Pediatrics. 17th Edition. Philadelphia: Saunders, 2004:623-40.
    • (2004) Nelson's Textbook of Pediatrics , pp. 623-640
    • Stoll, B.J.1
  • 54
    • 22244462944 scopus 로고    scopus 로고
    • Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003
    • PUBMED: 15999007]
    • Stoll BJ, Hansen NI, Higgins RD, Fanaroff AA, Duara S, Goldberg R, et al. National Institute of Child Health and Human Development. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003. Pediatric Infectious Disease Journal 2005;24(7):635-9. [PUBMED: 15999007]
    • (2005) Pediatric Infectious Disease Journal , vol.24 , Issue.7 , pp. 635-639
    • Stoll, B.J.1    Hansen, N.I.2    Higgins, R.D.3    Fanaroff, A.A.4    Duara, S.5    Goldberg, R.6
  • 55
    • 0032962172 scopus 로고    scopus 로고
    • Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study
    • PUBMED: 10363572]
    • Tanaka K, Ikeda M, Nozaki A, Kato N, Tsuda H, Saito S, et al. Lactoferrin inhibits hepatitis C virus viremia in patients with chronic hepatitis C: a pilot study. Japanese Journal of Cancer Research 1999;90(4):367-71. [PUBMED: 10363572]
    • (1999) Japanese Journal of Cancer Research , vol.90 , Issue.4 , pp. 367-371
    • Tanaka, K.1    Ikeda, M.2    Nozaki, A.3    Kato, N.4    Tsuda, H.5    Saito, S.6
  • 56
    • 77953285465 scopus 로고    scopus 로고
    • Influence of bovine lactoferrin on selected probiotic bacteria and intestinal pathogens
    • Tian H, Maddox IS, Ferguson LR, Shu Q. Influence of bovine lactoferrin on selected probiotic bacteria and intestinal pathogens. Biometals 2010;23(3):593-6.
    • (2010) Biometals , vol.23 , Issue.3 , pp. 593-596
    • Tian, H.1    Maddox, I.S.2    Ferguson, L.R.3    Shu, Q.4
  • 58
    • 0036191042 scopus 로고    scopus 로고
    • Bovine lactoferrin and lactoferricin derived from milk: production and applications
    • PUBMED: 11908633]
    • Tomita M, Wakabayashi H, Yamauchi K, Teraguchi S, Hayasawa H. Bovine lactoferrin and lactoferricin derived from milk: production and applications. Biochemistry and Cell Biology 2002;80(1):109-12. [PUBMED: 11908633]
    • (2002) Biochemistry and Cell Biology , vol.80 , Issue.1 , pp. 109-112
    • Tomita, M.1    Wakabayashi, H.2    Yamauchi, K.3    Teraguchi, S.4    Hayasawa, H.5
  • 60
    • 84920263812 scopus 로고    scopus 로고
    • Lactoferrin for prevention of neonatal sepsis
    • PUBMED: 24935001
    • Turin CG, Zea-Vera A, Pezo A, Cruz K, Zegarra J, Bellomo S, et al. NEOLACTO Research Group. Lactoferrin for prevention of neonatal sepsis. Biometals 2014;27(5):1007-16. [DOI: 10.1007/s10534-014-9754-3; PUBMED: 24935001]
    • (2014) Biometals , vol.27 , Issue.5 , pp. 1007-1016
    • Turin, C.G.1    Zea-Vera, A.2    Pezo, A.3    Cruz, K.4    Zegarra, J.5    Bellomo, S.6
  • 61
    • 28344457682 scopus 로고    scopus 로고
    • Lactoferrin: an important host defence against microbial and viral attack
    • PUBMED: 16261253
    • Valenti P, Antonini G. Lactoferrin: an important host defence against microbial and viral attack. Cellular and Molecular Life Sciences 2005;62(22):2576-87. [DOI: 10.1007/s00018-005-5372-0; PUBMED: 16261253]
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2576-2587
    • Valenti, P.1    Antonini, G.2
  • 62
    • 37249093508 scopus 로고    scopus 로고
    • Prophylaxis with lactoferrin, a novel antimicrobial agent, enhances survival in a neonatal rat model of co-infection
    • PUBMED: 18029319]
    • Venkatesh M, Pham D, Kong L, Weisman L. Prophylaxis with lactoferrin, a novel antimicrobial agent, enhances survival in a neonatal rat model of co-infection. Advances in Therapy 2007;24(5):941-54. [PUBMED: 18029319]
    • (2007) Advances in Therapy , vol.24 , Issue.5 , pp. 941-954
    • Venkatesh, M.1    Pham, D.2    Kong, L.3    Weisman, L.4
  • 63
    • 0004263777 scopus 로고
    • 3rd Edition. Philadelphia, London: WB Saunders,
    • Volpe JJ. Neurology of the Newborn. 3rd Edition. Philadelphia, London: WB Saunders, 1995.
    • (1995) Neurology of the Newborn
    • Volpe, J.J.1
  • 64
    • 0024842051 scopus 로고
    • Lactoferrin can protect mice against a lethal dose of Escherichia coli in experimental infection in vivo
    • PUBMED: 2690922]
    • Zagulski T, Lipinski P, Zagulska A, Broniek S, Jarzabek Z. Lactoferrin can protect mice against a lethal dose of Escherichia coli in experimental infection in vivo. British Journal of Experimental Pathology 1989;70(6):697-704. [PUBMED: 2690922]
    • (1989) British Journal of Experimental Pathology , vol.70 , Issue.6 , pp. 697-704
    • Zagulski, T.1    Lipinski, P.2    Zagulska, A.3    Broniek, S.4    Jarzabek, Z.5
  • 65
    • 15744389852 scopus 로고    scopus 로고
    • Hospital-acquired neonatal infections in developing countries
    • PUBMED: 15794973
    • Zaidi AK, Huskins WC, Thaver D, Bhutta ZA, Abbas Z, Goldmann DA. Hospital-acquired neonatal infections in developing countries. Lancet 2005;365(9465):1175-88. [DOI: 10.1016/S0140-6736(05)71881-X; PUBMED: 15794973]
    • (2005) Lancet , vol.365 , Issue.9465 , pp. 1175-1188
    • Zaidi, A.K.1    Huskins, W.C.2    Thaver, D.3    Bhutta, Z.A.4    Abbas, Z.5    Goldmann, D.A.6
  • 66
    • 85021767712 scopus 로고    scopus 로고
    • Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants
    • Pammi M, Abrams SA. Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2010, Issue 5. [DOI: 10.1002/14651858.CD007137.pub2]
    • (2010) Cochrane Database of Systematic Reviews , Issue.5
    • Pammi, M.1    Abrams, S.A.2
  • 67
    • 80155128889 scopus 로고    scopus 로고
    • Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants
    • Pammi M, Abrams SA. Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2011, Issue 10. [DOI: 10.1002/14651858.CD007137.pub3]
    • (2011) Cochrane Database of Systematic Reviews , Issue.10
    • Pammi, M.1    Abrams, S.A.2
  • 68
    • 84934326069 scopus 로고    scopus 로고
    • Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants
    • Pammi M, Abrams SA. Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2015, Issue 2. [DOI: 10.1002/14651858.CD007137.pub4]
    • (2015) Cochrane Database of Systematic Reviews , Issue.2
    • Pammi, M.1    Abrams, S.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.