Chronic stress and intestinal barrier dysfunction: Glucocorticoid receptor and transcription repressor HES1 regulate tight junction protein Claudin-1 promoter

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Zheng, Gen ^a   Victor Fon, Gordon ^a   Meixner, Walter ^a   Creekmore, Amy ^a   Zong, Ye ^b   Michael Dame, M K ^a   Colacino, Justin ^c   Dedhia, Priya H ^a   Hong, Shuangsong ^a   Wiley, John W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 1; CLDN1 PROTEIN, HUMAN; GLUCOCORTICOID RECEPTOR; HES1 PROTEIN, HUMAN; NR3C1 PROTEIN, HUMAN; PROTEIN BINDING; TRANSCRIPTION FACTOR HES 1;

ANIMAL; CACO-2 CELL LINE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INTESTINE MUCOSA; MENTAL STRESS; METABOLISM; PHYSIOLOGICAL STRESS; PROMOTER REGION; RAT;

ANIMALS; CACO-2 CELLS; CELL DIFFERENTIATION; CLAUDIN-1; GENE EXPRESSION REGULATION; HUMANS; INTESTINAL MUCOSA; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; RECEPTORS, GLUCOCORTICOID; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL; TRANSCRIPTION FACTOR HES-1;

EID: 85021747050     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-04755-w     Document Type: Article

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