Human colonic crypts in culture: Segregation of immunochemical markers in normal versus adenoma-derived

Laboratory Investigation

Volumn 94, Issue 2, 2014, Pages 222-234

  Dame, Michael K ^a   Jiang, Yan ^b   Appelman, Henry D ^a   Copley, Kelly D ^a   McClintock, Shannon D ^a   Aslam, Muhammad Nadeem ^a   Attili, Durga ^a   Elmunzer, B Joseph ^a   Brenner, Dean E ^b,c   Varani, James ^a   Turgeon, D Kim ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

adenoma; apoptosis; chemoprevention; colon crypt culture; cytokeratin 20; Lgr5; mucin 2

Indexed keywords

BIOLOGICAL MARKER; CASPASE 3; CYTOKERATIN 20; G PROTEIN COUPLED RECEPTOR; KI 67 ANTIGEN; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; MUCIN 2; PROTEIN BAX; UNCLASSIFIED DRUG; UVOMORULIN;

ADULT; AGED; ARTICLE; BASAL CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CLINICAL ARTICLE; COLON ADENOMA; COLON BIOPSY; COLON MUCOSA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INTESTINE CRYPT; LAMINA PROPRIA; MALE; MIDDLE AGED; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; YOUNG ADULT;

ADENOMA; BIOLOGICAL MARKERS; CADHERINS; CALCIUM; COLLAGEN; COLON; COLONIC NEOPLASMS; DRUG COMBINATIONS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; KERATIN-20; KI-67 ANTIGEN; LAMININ; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MUCIN-2; PROTEOGLYCANS; RECEPTORS, G-PROTEIN-COUPLED; TISSUE CULTURE TECHNIQUES;

EID: 84893250888     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2013.145     Document Type: Article

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