Activation of an SP binding site is crucial for the expression of Claudin 1 in rat epididymal principal cells

Biology of Reproduction

Volumn 76, Issue 5, 2007, Pages 825-832

  Dufresne, Julie ^a   Cyr, Daniel G ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

Blood epididymal barrier; Epididymis; Gene regulation; Male reproductive tract; RCE cells; SP1; Tight junctions; Transcription factors

Indexed keywords

CLAUDIN 1; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL LINE; CLDN1 GENE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA FLANKING REGION; EPIDIDYMIS; EXPRESSION VECTOR; GEL MOBILITY SHIFT ASSAY; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSFECTION; MALE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RAT; REPORTER GENE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; TATA BOX; TIGHT JUNCTION; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

5' FLANKING REGION; ANIMALS; BASE SEQUENCE; BINDING SITES; BIOTRANSFORMATION; CELLS, CULTURED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPIDIDYMIS; GENES, REPORTER; LUCIFERASES; MALE; MEMBRANE PROTEINS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PLASMIDS; RATS; SP1 TRANSCRIPTION FACTOR; TIGHT JUNCTIONS; TRANSFECTION;

RATTUS;

EID: 34247528998     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.106.057430     Document Type: Article

References (39)

1. Cyr DG, Finnson KW, Dufresne J, Gregory M. Cellular interactions and the blood-epididymal barrier. In: Robaire B, Hinton B (eds.), The Epididymis: from Molecules to Clinical Practice. New York: Plenum Press; 2002:103-118.
2. Friend DS, Gilula NB. Variations in tight and gap junctions in mammalian tissues. J Cell Biol 1972; 53:758-776.
3. Cyr DG, Robaire B, Hermo L. Structure and turnover of junctional complexes between principal cells of the rat epididymis. Microsc Res Tech 1995; 30:54-66.
4. Yap AS, Mullin JM, Stevenson BR. Molecular analyses of tight junction physiology: insights and paradoxes. J Membr Biol 1998; 163:159-167.
5. Mitic LL, Unger VM, Anderson JM. Expression, solubilization, and biochemical characterization of the tight junction transmembrane protein claudin-4. Protein Sci 2003; 12:218-227.
6. Staehelin LA. Structure and function of intercellular junctions. Int Rev Cytol 1974; 39:191-283.
7. Shin K, Fogg VC, Margolis B. Tight Junctions and Cell Polarity. Annu Rev Cell Dev Biol 2006; 22:207-235.
8. Furuse M, Tsukita S. Claudins in occluding junctions of humans and flies. Trends Cell Biol 2006; 16:181-188.
9. Spring KR. Routes and mechanism of fluid transport by epithelia. Annu Rev Physiol 1998; 60:105-119.
10. Anderson JM. Cell signalling: MAGUK magic. Curr Biol 1996; 6:382-384.
11. Haskins J, Gu L, Wittchen ES, Hibbard J, Stevenson BR. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol 1998; 141:199-208.
12. Wittchen ES, Haskins J, Stevenson BR. Protein interactions at the tight junction: actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. J Biol Chem 1999; 274: 35179-35185.
13. Keon BH, Schafer S, Kuhn C, Grund C, Franke WW. Symplekin, a novel type of tight junction plaque protein. J Cell Biol 1996; 134:1003-1018.
14. Cordenonsi M, D'Atri F, Hammar E, Parry DA, Kendrick-Jones J, Shore D, Citi S. Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin. J Cell Biol 1999; 147: 1569-1582.
15. Stevenson BR, Keon BH. The tight junction: morphology to molecules. Annu Rev Cell Dev Biol 1998; 14:89-109.
16. Furuse M, Sasaki H, Fujimoto K, Tsukita S. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol 1998; 143:391-401.
17. Morita K, Furuse M, Fujimoto K, Tsukita S. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Nad Acad Sci U S A 1999; 96:511-516.
18. Van Itallie CM, Rogan S, Yu AS, Seminario-Vidal L, Holmes J, Anderson JM. Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities. Am J Physiol Renal Physiol 2006; 291:F1288-F1299.
19. Van Itallie CM, Anderson JM. Claudins and epithelial paracellular transport. Annu Rev Physiol 2006; 68:403-429.
20. Levy S, Robaire B. Segment-specific changes with age in the expression of junctional proteins and the permeability of the blood-epididymis barrier in rats. Biol Reprod 1999; 60:1392-1401.
21. Cyr DG, Hermo L, Egenberger N, Mertineit C, Trasler JM, Laird DW. Cellular immunolocalization of occludin during embryonic and postnatal development of the mouse testis and epididymis. Endocrinology 1999; 140:3815-3825.
22. Gregory M, Dufresne J, Hermo L, Cyr D. Claudin-1 is not restricted to tight junctions in the rat epididymis. Endocrinology 2001; 142:854-863.
23. Guan X, Inai T, Shibata Y. Segment-specific expression of tight junction proteins, claudin-2 and -10, in the rat epididymal epithelium. Arch Histol Cytol 2005; 68:213-225.
24. Gregory M, Cyr DG. Identification of multiple claudins in the rat epididymis. Mol Reprod Dev 2006; 73:580-588.
25. Suzuki F, Nagano T. Development of tight junctions in the caput epididymal epithelium of the mouse. Dev Biol 1978; 63:321-334.
26. Swisshelm K, Machl A, Planitzer S, Robertson R, Kubbies M, Hosier S. SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily. Gene 1999; 226:285-295.
27. Miwa N, Furuse M, Tsukita S, Niikawa N, Nakamura Y, Furukawa Y. Involvement of claudin-1 in the beta-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers. Oncol Res 2000; 12: 469-476.
28. Martinez-Estrada OM, Culleres A, Soriano FX, Peinado H, Bolos V, Martinez FO, Reina M, Cano A, Fabre M, Vilaro S. The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells. Biochem J 2006; 394:449-457.
29. Ohkubo T, Ozawa M. The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation. J Cell Sci 2004; 117:1675-1685.
30. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-159.
31. Dufresne J, St-Pierre N, Viger RS, Hermo L, Cyr DG. Characterization of a novel rat epididymal cell line to study epididymal function. Endocrinology 2005; 146:4710-4720.
32. Krämer F, White K, Kubbies M, Swisshelm K, Weber BH. Genomic organization of claudin-1 and its assessment in hereditary and sporadic breast cancer. Hum Genet 2000; 107:249-256.
33. Smale ST, Kadonaga JT. The RNA polymerase II core promoter. Annu Rev Biochem 2003; 72:449-479.
34. Seenundun S, Robaire B. Cloning and characterization of the 5alpha-reductase type 2 promoter in the rat epididymis. Biol Reprod 2005; 72: 851-861.
35. Li L, He S, Sun JM, Davie JR. Gene regulation by Sp1 and Sp3. Biochem Cell Biol 2004; 82:460-471.
36. Lan ZJ, Lye RJ, Holic N, Labus JC, Hinton BT. Involvement of polyomavirus enhancer activator 3 in the regulation of expression of gamma-glutamyl transpeptidase messenger ribonucleic acid-IV in the rat epididymis. Biol Reprod 1999; 60:664-673.
37. Honda H, Pazin MJ, Ji H, Wemyj RP, Morin PJ. Crucial roles of Sp1 and epigenetic modifications in the regulation of the CLDN4 promoter in ovarian cancer cells. J Biol Chem 2006; 281:21433-21444.
38. Luk JM, Tong MK, Mok BW, Tam PC, Yeung WS, Lee KF. Sp1 site is crucial for the mouse claudin-19 gene expression in the kidney cells. FEBS Lett 2004; 578:251-256.
39. Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 1998; 141:1539-1550.