An exome sequencing study to assess the role of rare genetic variation in pulmonary fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 196, Issue 1, 2017, Pages 82-93

  Petrovski, Slavé ^a,b   Todd, Jamie L ^c,d   Durheim, Michael T ^c,d   Wang, Quanli ^a   Chien, Jason W ^e   Kelly, Fran L ^c   Frankel, Courtney ^c   Mebane, Caroline M ^a   Ren, Zhong ^a   Bridgers, Joshua ^a   Urban, Thomas J ^f   Malone, Colin D ^a   Copeland, Ashley Finlen ^c   Brinkley, Christie ^c   Allen, Andrew S ^g   O'Riordan, Thomas ^e   McHutchison, John G ^e   Palmer, Scott M ^c,d   Goldstein, David B ^a  

^a Department of Medicine   (United States)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^e GILEAD SCIENCES   (United States)

^f UNC Hamner Institute for Drug Safety Sciences   (United States)

^g DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Collapsing analysis; Exome sequencing; Genetics; Interstitial lung disease; Pulmonary fibrosis

Indexed keywords

DNA; MUCIN 5B; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; ARTICLE; CASE CONTROL STUDY; COMPUTER ASSISTED TOMOGRAPHY; DNA EXTRACTION; FEMALE; GENE; GENE STRUCTURE; GENETIC RISK; GENETIC VARIATION; GENOTYPING TECHNIQUE; HUMAN; INTERSTITIAL PNEUMONIA; LUNG FIBROSIS; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; PARN GENE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; RTEL1 GENE; SEROLOGY; TELOMERE; WHOLE EXOME SEQUENCING; EXOME; FIBROSING ALVEOLITIS; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED;

EXOME; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; MIDDLE AGED;

EID: 85021728012     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201610-2088OC     Document Type: Article

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