Clinical outcomes of lung transplant recipients with telomerase mutations

Journal of Heart and Lung Transplantation

Volumn 34, Issue 10, 2015, Pages 1318-1324

  Tokman, Sofya ^a   Singer, Jonathan P ^a   Devine, Megan S ^b   Westall, Glen P ^c   Aubert, John David ^d   Tamm, Michael ^e   Snell, Gregory I ^c   Lee, Joyce S ^a   Goldberg, Hilary J ^f   Kukreja, Jasleen ^a   Golden, Jeffrey A ^a   Leard, Lorriana E ^a   Garcia, Christine K ^b   Hays, Steven R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c ALFRED HOSPITAL   (Australia)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e UNIVERSITY HOSPITAL BASEL   (Switzerland)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

lung transplantation; pulmonary fibrosis; telomerase mutations; telomere; telomere syndrome

Indexed keywords

AZATHIOPRINE; CALCINEURIN INHIBITOR; MYCOPHENOLATE MOFETIL; PREDNISONE; TACROLIMUS; TELOMERASE REVERSE TRANSCRIPTASE; VORICONAZOLE; TELOMERASE;

ACUTE GRAFT REJECTION; ACUTE KIDNEY FAILURE; ADULT; ANEMIA; ARTICLE; ASPERGILLUS; BACTERIAL INFECTION; BRONCHIOLITIS OBLITERANS; BRONCHOSCOPY; CANDIDA TROPICALIS; CHOLESTASIS; CHROMOSOME MUTATION; CHRONIC DISEASE; CHRONIC LUNG ALLOGRAFT DYSFUNCTION; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; DECORTICATION; DISEASE SURVEILLANCE; EMPYEMA; FEMALE; GENETIC ANALYSIS; GRAFT DYSFUNCTION; GRAFT RECIPIENT; HUMAN; HUMAN TISSUE; HYPERTRANSAMINASEMIA; KIDNEY FAILURE; LEUKOPENIA; LOWER RESPIRATORY TRACT INFECTION; LUNG LAVAGE; LUNG TRANSPLANTATION; MALE; MALIGNANT NEOPLASTIC DISEASE; MYCOSIS; OUTCOME ASSESSMENT; PNEUMONIA; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RECURRENT DISEASE; RETROSPECTIVE STUDY; SPIROMETRY; STAPHYLOCOCCUS AUREUS; TELOMERASE MUTATION; THROMBOCYTOPENIA; TRANSBRONCHIAL BIOPSY; CLINICAL TRIAL; GENETICS; GRAFT REJECTION; MIDDLE AGED; MULTICENTER STUDY; MUTATION; PULMONARY FIBROSIS; TREATMENT OUTCOME;

FEMALE; GRAFT REJECTION; HUMANS; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; MUTATION; PULMONARY FIBROSIS; RETROSPECTIVE STUDIES; TELOMERASE; TREATMENT OUTCOME;

EID: 84943365560     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2015.05.002     Document Type: Article

References (30)

1. P.W. Noble, C.E. Barkauskas, and D. Jiang Pulmonary fibrosis: patterns and perpetrators J Clin Invest 122 2012 2756 2762
2. A. Diaz de Leon, J.T. Cronkhite, A.L. Katzenstein, and et al. Telomere lengths, pulmonary fibrosis and telomerase (TERT) mutations PLoS One 5 2010 e10680
3. R.T. Calado, and N.S. Young Telomere diseases N Engl J Med 361 2009 2353 2365
4. R. Borie, C. Kannengiesser, and B. Crestani Familial forms of nonspecific interstitial pneumonia/idiopathic pulmonary fibrosis: clinical course and genetic background Curr Opin Pulm Med 18 2012 455 461
5. H. Yamaguchi, G.M. Baerlocher, P.M. Lansdorp, and et al. Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome Blood 102 2003 916 918
6. R.T. Calado, J.A. Regal, D.E. Kleiner, and et al. A spectrum of severe familial liver disorders associate with telomerase mutations PLoS One 4 2009 e7926
7. D. Hartmann, U. Srivastava, M. Thaler, and et al. Telomerase gene mutations are associated with cirrhosis formation Hepatology 53 2011 1608 1617
8. M.M. Gramatges, and A.A. Bertuch Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy Transl Res 162 2013 353 363
9. Placebo-controlled study of mycophenolate mofetil combined with cyclosporin and corticosteroids for prevention of acute rejection European Mycophenolate Mofetil Cooperative Study Group Lancet 345 1995 1321 1325
10. A blinded, randomized clinical trial of mycophenolate mofetil for the prevention of acute rejection in cadaveric renal transplantation The Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group Transplantation 61 1996 1029 1037
11. S. Husain, D.L. Paterson, S. Studer, and et al. Voriconazole prophylaxis in lung transplant recipients Am J Transplant 6 2006 3008 3016
12. L.L. Silhan, P.D. Shah, D.C. Chambers, and et al. Lung transplantation in telomerase mutation carriers with pulmonary fibrosis Eur Respir J 44 2014 178 187
13. R. Borie, C. Kannengiesser, S. Hirschi, and et al. Severe hematologic complications after lung transplantation in patients with telomerase complex mutations J Heart Lung Transplant 2015 3458-46
14. N. Giri, R. Lee, A. Faro, and et al. Lung transplantation for pulmonary fibrosis in dyskeratosis congenita: case report and systematic literature review BMC Blood Disord 11 2011 3
15. K.D. Tsakiri, J.T. Cronkhite, P.J. Kuan, and et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase Proc Natl Acad Sci U S A 104 2007 7552 7557
16. G. Raghu, H.R. Collard, J.J. Egan, and et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management Am J Respir Crit Care Med 183 2011 788 824
17. S. Stewart, M.C. Fishbein, G.I. Snell, and et al. Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection J Heart Lung Transplant 26 2007 1229 1242
18. J.D. Christie, M. Carby, R. Bag, and et al. Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part II: definition. A consensus statement of the International Society for Heart and Lung Transplantation J Heart Lung Transplant 24 2005 1454 1459
19. G.M. Verleden, G. Raghu, K.C. Meyer, and et al. A new classification system for chronic lung allograft dysfunction J Heart Lung Transplant 33 2014 127 133
20. J.D. Christie, L.B. Edwards, A.Y. Kucheryavaya, and et al. The Registry of the International Society for Heart and Lung Transplantation: Twenty-eighth Adult Lung and Heart-Lung Transplant Report - 2011 J Heart Lung Transplant 30 2011 1104 1122
21. J.D. Christie, L.B. Edwards, A.Y. Kucheryavaya, and et al. The Registry of the International Society for Heart and Lung Transplantation: 29th Adult Lung and Heart-Lung Transplant Report - 2012 J Heart Lung Transplant 31 2012 1073 1086
22. I.P. Neuringer Posttransplant lymphoproliferative disease after lung transplantation Clin Dev Immunol 2013 2013 430209
23. H. Yamaguchi, R.T. Calado, H. Ly, and et al. Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia N Engl J Med 352 2005 1413 1424
24. George G, Rosas IO, Cui Y, et al. Short telomeres, telomeropathy and subclinical extra-pulmonary organ damage in patients with interstitial lung disease. Chest 2014;147:1549-57.
25. P.J. Hohensinner, J.J. Goronzy, and C.M. Weyand Telomere dysfunction, autoimmunity and aging Aging Dis 2 2011 524 537
26. R.M. Cawthon, K.R. Smith, E. O'Brien, and et al. Association between telomere length in blood and mortality in people aged 60 years or older Lancet 361 2003 393 395
27. J.L. Todd, and S.M. Palmer Bronchiolitis obliterans syndrome: the final frontier for lung transplantation Chest 140 2011 502 508
28. X.J. Zuo, Y. Matsumura, J. Prehn, and et al. Cytokine gene expression in rejecting and tolerant rat lung allograft models: analysis by RT-PCR Transpl Immunol 3 1995 151 161
29. A. Jaramillo, F.G. Fernandez, E.Y. Kuo, and et al. Immune mechanisms in the pathogenesis of bronchiolitis obliterans syndrome after lung transplantation Pediatr Transplant 9 2005 84 93
30. T. Funakoshi, A. Latif, and M.D. Galsky Risk of hematologic toxicities in patients with solid tumors treated with everolimus: a systematic review and meta-analysis Crit Rev Oncol Hematol 88 2013 30 41