The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1

Nature Cell Biology

Volumn 19, Issue 7, 2017, Pages 820-832

  Yuan, Ji Hang ^a   Liu, Xiao Ning ^a   Wang, Tian Tian ^a   Pan, Wei ^a   Tao, Qi Fei ^a   Zhou, Wei Ping ^a   Wang, Fang ^a   Sun, Shu Han ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AS1 PROTEIN; ISOPROTEIN; LONG UNTRANSLATED RNA; MBNL3 PROTEIN; MESSENGER RNA; MICRORNA 24; OCTAMER TRANSCRIPTION FACTOR 4; ONCOPROTEIN; PXN PROTEIN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ARGONAUTE PROTEIN; CARRIER PROTEIN; EIF2C2 PROTEIN, HUMAN; MBNL3 PROTEIN, HUMAN; MBNL3 PROTEIN, MOUSE; MICRORNA; MIRN24 MICRORNA, HUMAN; NANOG PROTEIN, HUMAN; PAXILLIN; POU5F1 PROTEIN, HUMAN; PROTEIN BINDING; PXN PROTEIN, HUMAN; PXN-AS1 NON-CODING RNA, HUMAN; RNA BINDING PROTEIN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

3' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; ARTICLE; CANCER PROGNOSIS; CARCINOGENESIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; TRANSCRIPTOMICS; TRANSLATION ELONGATION; UPREGULATION; ANIMAL; BINDING SITE; C57BL MOUSE; CELL PROLIFERATION; EXON; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HEP-G2 CELL LINE; HIGH THROUGHPUT SEQUENCING; LIVER TUMOR; MALE; METABOLISM; MOUSE; NUDE MOUSE; PROCEDURES; RNA INTERFERENCE; TIME FACTOR; TUMOR VOLUME;

3' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; ANIMALS; ARGONAUTE PROTEINS; BINDING SITES; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CELL PROLIFERATION; EXONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, NUDE; MICRORNAS; NANOG HOMEOBOX PROTEIN; OCTAMER TRANSCRIPTION FACTOR-3; PAXILLIN; PROTEIN BINDING; RNA INTERFERENCE; RNA, LONG NONCODING; RNA-BINDING PROTEINS; SOXB1 TRANSCRIPTION FACTORS; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; UP-REGULATION;

EID: 85021724151     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3538     Document Type: Article

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