-
1
-
-
77949809397
-
Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk
-
PMID: 20308626
-
Malik VS, Popkin BM, Bray GA, Despres JP, Hu FB. Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation. 2010; 121: 1356–1364. https: //doi.org/10.1161/CIRCULATIONAHA.109.876185 PMID: 20308626
-
(2010)
Circulation
, vol.121
, pp. 1356-1364
-
-
Malik, V.S.1
Popkin, B.M.2
Bray, G.A.3
Despres, J.P.4
Hu, F.B.5
-
2
-
-
65349195631
-
The obesity, metabolic syndrome, and type 2 diabetes mellitus pandemic: Part i. increased cardiovascular disease risk and the importance of atherogenic dyslipidemia in persons with the metabolic syndrome and type 2 diabetes mellitus
-
PMID: 19614799
-
Ginsberg HN, MacCallum PR. The obesity, metabolic syndrome, and type 2 diabetes mellitus pandemic: Part I. Increased cardiovascular disease risk and the importance of atherogenic dyslipidemia in persons with the metabolic syndrome and type 2 diabetes mellitus. J Cardiometab Syndr. 2009; 4: 113–119. https: //doi.org/10.1111/j.1559-4572.2008.00044.x PMID: 19614799
-
(2009)
J Cardiometab Syndr
, vol.4
, pp. 113-119
-
-
Ginsberg, H.N.1
MacCallum, P.R.2
-
3
-
-
4444228888
-
-
Geneva (Switzerland): World Health Organization
-
Obesity and overweight. Geneva (Switzerland): World Health Organization; 2014. Available: www.who.int/mediacentre/factsheets/fs311/en/
-
(2014)
Obesity and Overweight
-
-
-
4
-
-
85010930965
-
Evolution of pharmacological obesity treatments: Focus on adverse side-effect profiles
-
PMID: 26936802
-
Krentz AJ, Fujioka K, Hompesch M. Evolution of pharmacological obesity treatments: focus on adverse side-effect profiles. Diabetes Obes Metab. 2016; 18: 558–570. https: //doi.org/10.1111/dom.12657 PMID: 26936802
-
(2016)
Diabetes Obes Metab
, vol.18
, pp. 558-570
-
-
Krentz, A.J.1
Fujioka, K.2
Hompesch, M.3
-
5
-
-
84907018279
-
Characterization of a shortened model of diet alternation in female rats: Effects of the cb1 receptor antagonist rimonabant on food intake and anxiety-like behavior
-
PMID: 25011007
-
Blasio A, Rice KC, Sabino V, Cottone P. Characterization of a shortened model of diet alternation in female rats: effects of the CB1 receptor antagonist rimonabant on food intake and anxiety-like behavior. Behav Pharmacol. 2014; 25: 609–617. https: //doi.org/10.1097/FBP.0000000000000059 PMID: 25011007
-
(2014)
Behav Pharmacol
, vol.25
, pp. 609-617
-
-
Blasio, A.1
Rice, K.C.2
Sabino, V.3
Cottone, P.4
-
6
-
-
33845874637
-
Drug treatments for obesity: Orlistat, sibutramine, and rimonabant
-
PMID: 17208644
-
Padwal RS, Majumdar SR. Drug treatments for obesity: orlistat, sibutramine, and rimonabant. Lancet. 2007; 369: 71–77. https: //doi.org/10.1016/S0140-6736(07)60033-6 PMID: 17208644
-
(2007)
Lancet
, vol.369
, pp. 71-77
-
-
Padwal, R.S.1
Majumdar, S.R.2
-
7
-
-
84890075093
-
Macrocytic anemia and thrombocytopenia induced by orlistat
-
PMID: 24719628
-
Palacios-Martinez D, Garcia-Alvarez JC, Montero-Santamaria N, Villar-Ruiz OP, Ruiz-Garcia A, Diaz-Alonso RA. Macrocytic anemia and thrombocytopenia induced by orlistat. Int J Endocrinol Metab. 2013; 11: e6721. https: //doi.org/10.5812/ijem.6721 PMID: 24719628
-
(2013)
Int J Endocrinol Metab
, vol.11
, pp. e6721
-
-
Palacios-Martinez, D.1
Garcia-Alvarez, J.C.2
Montero-Santamaria, N.3
Villar-Ruiz, O.P.4
Ruiz-Garcia, A.5
Diaz-Alonso, R.A.6
-
8
-
-
84857099986
-
Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models
-
PMID: 22355316
-
Liang Y, Arakawa K, Ueta K, Matsushita Y, Kuriyama C, Martin T, Du F, Liu Y, Xu J, Conway B, et al. Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models. Plos One. 2012; 7: e30555. https: //doi.org/10.1371/journal.pone.0030555 PMID: 22355316
-
(2012)
Plos One
, vol.7
, pp. e30555
-
-
Liang, Y.1
Arakawa, K.2
Ueta, K.3
Matsushita, Y.4
Kuriyama, C.5
Martin, T.6
Du, F.7
Liu, Y.8
Xu, J.9
Conway, B.10
-
9
-
-
84907884824
-
Diacylglycerol acyltransferase-2 (dgat2) and monoacylglycerol acyltransferase-2 (mgat2) interact to promote triacylglycerol synthesis
-
PMID: 25164810
-
Jin Y, McFie PJ, Banman SL, Brandt C, Stone SJ. Diacylglycerol acyltransferase-2 (DGAT2) and monoacylglycerol acyltransferase-2 (MGAT2) interact to promote triacylglycerol synthesis. J Biol Chem. 2014; 289: 28237–28248. https: //doi.org/10.1074/jbc.M114.571190 PMID: 25164810
-
(2014)
J Biol Chem
, vol.289
, pp. 28237-28248
-
-
Jin, Y.1
McFie, P.J.2
Banman, S.L.3
Brandt, C.4
Stone, S.J.5
-
10
-
-
84875477489
-
Extract of wax gourd peel prevents high-fat diet-induced hyperlipidemia in C57bl/6 mice via the inhibition of the ppargamma pathway
-
PMID: 23533476
-
Gu M, Fan S, Liu G, Guo L, Ding X, Lu Y, Zhang Y, Ji G, Huang C. Extract of Wax Gourd Peel Prevents High-Fat Diet-Induced Hyperlipidemia in C57BL/6 Mice via the Inhibition of the PPARgamma Pathway. Evid Based Complement Alternat Med. 2013; 2013: 342561. https: //doi.org/10.1155/2013/342561 PMID: 23533476
-
(2013)
Evid Based Complement Alternat Med
, vol.2013
, pp. 342561
-
-
Gu, M.1
Fan, S.2
Liu, G.3
Guo, L.4
Ding, X.5
Lu, Y.6
Zhang, Y.7
Ji, G.8
Huang, C.9
-
11
-
-
77957726317
-
Simvastatin inhibited cardiac hypertrophy and fibrosis in apolipoprotein e-deficient mice fed a "western-style diet" by increasing PPAR alpha and gamma expression and reducing tc, mmp-9, and cat s levels
-
PMID: 20835264
-
Qin YW, Ye P, He JQ, Sheng L, Wang LY, Du J. Simvastatin inhibited cardiac hypertrophy and fibrosis in apolipoprotein E-deficient mice fed a "Western-style diet" by increasing PPAR alpha and gamma expression and reducing TC, MMP-9, and Cat S levels. Acta Pharmacol Sin. 2010; 31: 1350–1358. https: //doi.org/10.1038/aps.2010.109 PMID: 20835264
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 1350-1358
-
-
Qin, Y.W.1
Ye, P.2
He, J.Q.3
Sheng, L.4
Wang, L.Y.5
Du, J.6
-
12
-
-
80051522307
-
Murine diacylglycerol acyltransferase-2 (dgat2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum
-
PMID: 21680734
-
McFie PJ, Banman SL, Kary S, Stone SJ. Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum. J Biol Chem. 2011; 286: 28235–28246. https: //doi.org/10.1074/jbc.M111. 256008 PMID: 21680734
-
(2011)
J Biol Chem
, vol.286
, pp. 28235-28246
-
-
McFie, P.J.1
Banman, S.L.2
Kary, S.3
Stone, S.J.4
-
13
-
-
84914689445
-
A safety evaluation of canagliflozin: A first-in-class treatment for type 2 diabetes
-
PMID: 25340618
-
Boyle LD, Wilding JP. A safety evaluation of canagliflozin: a first-in-class treatment for type 2 diabetes. Expert Opin Drug Saf. 2014; 13: 1535–1544. https: //doi.org/10.1517/14740338.2014.959488 PMID: 25340618
-
(2014)
Expert Opin Drug Saf
, vol.13
, pp. 1535-1544
-
-
Boyle, L.D.1
Wilding, J.P.2
-
14
-
-
84888059660
-
Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea: A randomised trial
-
PMID: 24118688
-
Wilding JP, Charpentier G, Hollander P, González-Gálvez G, Mathieu C, Vercruysse F, Usiskin K, Law G, Black S, Canovatchel W, Meininger G. Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea: a randomised trial. Int J Clin Pract. 2013; 67: 1267–1682. https: //doi.org/10.1111/ijcp.12322 PMID: 24118688
-
(2013)
Int J Clin Pract
, vol.67
, pp. 1267-1682
-
-
Wilding, J.P.1
Charpentier, G.2
Hollander, P.3
González-Gálvez, G.4
Mathieu, C.5
Vercruysse, F.6
Usiskin, K.7
Law, G.8
Black, S.9
Canovatchel, W.10
Meininger, G.11
-
15
-
-
84857099986
-
Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models
-
PMID: 22355316
-
Liang Y, Arakawa K, Ueta K, Matsushita Y, Kuriyama C, Martin T, Du F, Liu Y, Xu J, Conway B, et al. Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models. Plos One. 2012; 7: e30555. https: //doi.org/10.1371/journal.pone.0030555 PMID: 22355316
-
(2012)
Plos One
, vol.7
, pp. e30555
-
-
Liang, Y.1
Arakawa, K.2
Ueta, K.3
Matsushita, Y.4
Kuriyama, C.5
Martin, T.6
Du, F.7
Liu, Y.8
Xu, J.9
Conway, B.10
-
16
-
-
84945958760
-
Canagliflozin treatment in patients with type 2 diabetes mellitus
-
PMID: 26523120
-
Triplitt C, Cornell S. Canagliflozin Treatment in Patients with Type 2 Diabetes Mellitus. Clin Med Insights Endocrinol Diabetes. 2015; 8: 73–81. https: //doi.org/10.4137/CMED.S31526 PMID: 26523120
-
(2015)
Clin Med Insights Endocrinol Diabetes
, vol.8
, pp. 73-81
-
-
Triplitt, C.1
Cornell, S.2
-
17
-
-
0036783050
-
The metabolic abnormalities associated with non-alcoholic fatty liver disease
-
PMID: 12406441
-
Haque M, Sanyal AJ. The metabolic abnormalities associated with non-alcoholic fatty liver disease. Best Pract Res Clin Gastroenterol. 2002; 16: 709–731. PMID: 12406441
-
(2002)
Best Pract Res Clin Gastroenterol
, vol.16
, pp. 709-731
-
-
Haque, M.1
Sanyal, A.J.2
-
18
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
PMID: 12840063
-
Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest. 2003; 112: 91–100. https: //doi.org/10.1172/JCI17797 PMID: 12840063
-
(2003)
J Clin Invest
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
19
-
-
33845542363
-
Weight gain induced by high-fat feeding involves increased liver oxidative stress
-
Milagro FI, Campion J, Martinez JA. Weight gain induced by high-fat feeding involves increased liver oxidative stress. Obesity (Silver Spring). 2006; 14: 1118–1123.
-
(2006)
Obesity silver Spring
, vol.14
, pp. 1118-1123
-
-
Milagro, F.I.1
Campion, J.2
Martinez, J.A.3
-
20
-
-
84945551290
-
Erchen decoction prevents high-fat diet induced metabolic disorders in C57bl/6 mice
-
PMID: 26504476
-
Gao BZ, Chen JC, Liao LH, Xu JQ, Lin XF, Ding SS. Erchen Decoction Prevents High-Fat Diet Induced Metabolic Disorders in C57BL/6 Mice. Evid Based Complement Alternat Med. 2015; 2015: 501272. https: //doi.org/10.1155/2015/501272 PMID: 26504476
-
(2015)
Evid Based Complement Alternat Med
, vol.2015
, pp. 501272
-
-
Gao, B.Z.1
Chen, J.C.2
Liao, L.H.3
Xu, J.Q.4
Lin, X.F.5
Ding, S.S.6
-
21
-
-
84930933375
-
Effects of Vitamin D supplementation and circuit training on indices of obesity and insulin resistance in t2d and Vitamin D deficient elderly women
-
PMID: 25566461
-
Kim HJ, Kang CK, Park H, Lee MG. Effects of vitamin D supplementation and circuit training on indices of obesity and insulin resistance in T2D and vitamin D deficient elderly women. J Exerc Nutrition Bio-chem. 2014; 18: 249–257. https: //doi.org/10.5717/jenb.2014.18.3.249 PMID: 25566461
-
(2014)
J Exerc Nutrition Bio-chem
, vol.18
, pp. 249-257
-
-
Kim, H.J.1
Kang, C.K.2
Park, H.3
Lee, M.G.4
-
22
-
-
84937435530
-
Analysis of renal functions and proteinuria in young obese adults
-
PMID: 25833358
-
You DY, Wu ZY, Wan JX, Cui J, Zou ZH. Analysis of renal functions and proteinuria in young obese adults. J Endocrinol Invest. 2015; 38: 901–908. https: //doi.org/10.1007/s40618-015-0272-0 PMID: 25833358
-
(2015)
J Endocrinol Invest
, vol.38
, pp. 901-908
-
-
You, D.Y.1
Wu, Z.Y.2
Wan, J.X.3
Cui, J.4
Zou, Z.H.5
-
23
-
-
84953791948
-
The selective sglt2 inhibitor ipragliflozin has a therapeutic effect on nonalcoholic steatohepatitis in mice
-
Honda Y, Imajo K, Kato T, Kessoku T, Ogawa Y, Tomeno W, Kato S, Mawatari H, Fujita K, Yoneda M, et al. The selective SGLT2 inhibitor ipragliflozin has a therapeutic effect on nonalcoholic steatohepatitis in mice. Plos One. 2016; 11: e146337.
-
(2016)
Plos One
, vol.11
, pp. e146337
-
-
Honda, Y.1
Imajo, K.2
Kato, T.3
Kessoku, T.4
Ogawa, Y.5
Tomeno, W.6
Kato, S.7
Mawatari, H.8
Fujita, K.9
Yoneda, M.10
-
24
-
-
84961615237
-
Ipragliflozin improves hepatic steatosis in obese mice and liver dysfunction in type 2 diabetic patients irrespective of body weight reduction
-
Komiya C, Tsuchiya K, Shiba K, Miyachi Y, Furuke S, Shimazu N, Yamaguchi S, Kanno K, Ogawa Y. Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction. Plos One. 2016; 11: e151511.
-
(2016)
Plos One
, vol.11
, pp. e151511
-
-
Komiya, C.1
Tsuchiya, K.2
Shiba, K.3
Miyachi, Y.4
Furuke, S.5
Shimazu, N.6
Yamaguchi, S.7
Kanno, K.8
Ogawa, Y.9
-
25
-
-
84953791948
-
The selective sglt2 inhibitor ipragliflozin has a therapeutic effect on nonalcoholic steatohepa-titis in mice
-
Honda Y, Imajo K, Kato T, Kessoku T, Ogawa Y, Tomeno W, Kato S, Mawatari H, Fujita K, Yoneda M, et al. The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepa-titis in Mice. Plos One. 2016; 11: e146337.
-
(2016)
Plos One
, vol.11
, pp. e146337
-
-
Honda, Y.1
Imajo, K.2
Kato, T.3
Kessoku, T.4
Ogawa, Y.5
Tomeno, W.6
Kato, S.7
Mawatari, H.8
Fujita, K.9
Yoneda, M.10
-
26
-
-
80051522307
-
Murine diacylglycerol acyltransferase-2 (dgat2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum
-
PMID: 21680734
-
McFie PJ, Banman SL, Kary S, Stone SJ. Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum. J Biol Chem. 2011; 286: 28235–28246. https: //doi.org/10.1074/jbc.M111. 256008 PMID: 21680734
-
(2011)
J Biol Chem
, vol.286
, pp. 28235-28246
-
-
McFie, P.J.1
Banman, S.L.2
Kary, S.3
Stone, S.J.4
-
27
-
-
82955170675
-
Auraptene regulates gene expression involved in lipid metabolism through pparalpha activation in diabetic obese mice
-
PMID: 22038981
-
Takahashi N, Senda M, Lin S, Goto T, Yano M, Sasaki T, Murakami S, Kawada T. Auraptene regulates gene expression involved in lipid metabolism through PPARalpha activation in diabetic obese mice. Mol Nutr Food Res. 2011; 55: 1791–1797. https: //doi.org/10.1002/mnfr.201100401 PMID: 22038981
-
(2011)
Mol Nutr Food Res
, vol.55
, pp. 1791-1797
-
-
Takahashi, N.1
Senda, M.2
Lin, S.3
Goto, T.4
Yano, M.5
Sasaki, T.6
Murakami, S.7
Kawada, T.8
-
28
-
-
60149095012
-
Time-course comparison of xenobiotic activators of car and pparalpha in mouse liver
-
PMID: 19136022
-
Ross PK, Woods CG, Bradford BU, Kosyk O, Gatti DM, Cunningham ML, Rusyn I. Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liver. Toxicol Appl Pharmacol. 2009; 235: 199–207. https: //doi.org/10.1016/j.taap.2008.12.011 PMID: 19136022
-
(2009)
Toxicol Appl Pharmacol
, vol.235
, pp. 199-207
-
-
Ross, P.K.1
Woods, C.G.2
Bradford, B.U.3
Kosyk, O.4
Gatti, D.M.5
Cunningham, M.L.6
Rusyn, I.7
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