Pre-natal and post-natal exposure to pet ownership and lung function in children: The Seven Northeastern Cities Study

Indoor Air

Volumn 27, Issue 6, 2017, Pages 1177-1189

  Hu, L W ^a   Qian, Z ^b   Dharmage, S C ^c   Liu, E ^b   Howard, S W ^b   Vaughn, M G ^b   Perret, J ^c   Lodge, C C ^c   Zeng, X W ^a   Yang, B Y ^a   Xu, S L ^a   Zhang, C ^a   Dong, G H ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SAINT LOUIS UNIVERSITY   (United States)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

children; exposure; gender difference; lung function; pets; prevention

Indexed keywords

'CURRENT; CHILD; CONFIDENCE INTERVAL; EXPOSURE; FORCED EXPIRATORY VOLUME IN 1; GENDER-DIFFERENCES; LUNG FUNCTION; ODD RATIOS; PET; PREVENTION;

BIOLOGICAL ORGANS;

ADOLESCENT; ANIMAL; BIRD; CAT; CHILD; CROSS-SECTIONAL STUDY; DOG; FEMALE; HUMAN; LUNG; LUNG FUNCTION TEST; MALE; PET ANIMAL; PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE;

ADOLESCENT; ANIMALS; BIRDS; CATS; CHILD; CROSS-SECTIONAL STUDIES; DOGS; FEMALE; HUMANS; LUNG; MALE; PETS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RESPIRATORY FUNCTION TESTS;

EID: 85021625811     PISSN: 09056947     EISSN: 16000668     Source Type: Journal    
DOI: 10.1111/ina.12401     Document Type: Article

References (92)

1. Stocks J, Hislop A, Sonnappa S. Early lung development: lifelong effect on respiratory health and disease. Lancet Respir Med. 2013;1:728-742.
2. van Putte-Katier N, van der Gugten AC, Uiterwaal CS, et al. Early life lung function and respiratory outcome in the first year of life. Eur Respir J. 2012;40:198-205.
3. Owens L, Laing IA, Zhang G, Le Souëf PN. Infant lung function predicts asthma persistence and remission in young adults. Respirology. 2017;22:289-294.
4. Postma DS, Bush A, van den Berge M. Risk factors and early origins of chronic obstructive pulmonary disease. Lancet. 2015;385:899-909.
5. Haibo X, Guoqun F. Studies on consumption of household pets: a review and perspective. J Mark Sci. 2015;11:1-21.
6. Xie ZY, Zhao D, Chen BR, et al. Association between pet ownership and coronary artery disease in a Chinese population. Medicine (Baltimore). 2017;96:e6466.
7. Simpson A, Lazic N, Belgrave DC, et al. Patterns of IgE responses to multiple allergen components and clinical symptoms at age 11 years. J Allergy Clin Immunol. 2015;136:1224-1231.
8. Ownby DR, Johnson CC, Peterson EL. Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA. 2002;288:963-972.
9. Nelson HS, Szefler SJ, Jacobs J, Huss K, Shapiro G, Sternberg AL. The relationships among environmental allergen sensitization, allergen exposure, pulmonary function, and bronchial hyperresponsiveness in the Childhood Asthma Management Program. J Allergy Clin Immunol. 1999;104:775-785.
10. Lowe LA, Woodcock A, Murray CS, Morris J, Simpson A, Custovic A. Lung function at age 3 years-effect of pet ownership and exposure to indoor allergens. Arch Pediatr Adolesc Med. 2004;158:996-1001.
11. Morrow CB, Raraigh KS, Green DM, et al. Cat and dog exposure and respiratory morbidities in cystic fibrosis. J Pediatr. 2014;165:830-835.
12. Lau S, Illi S, Sommerfeld C, et al. Early exposure to house-dust mite and cat allergens and development of childhood asthma: a cohort study. Lancet. 2000;356:1392-1397.
13. Campbell B, Raherison C, Lodge CJ, et al. The effects of growing up on a farm on adult lung function and allergic phenotypes: an international population-based study. Thorax. 2017;72:236-244.
14. Platts-Mills T, Vaughan J, Squillace S, et al. Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet. 2001;357:752-756.
15. Fuchs O, Genuneit J, Latzin P, et al. Farming environments and childhood atopy, wheeze, lung function, and exhaled nitric oxide. J Allergy Clin Immunol. 2012;130:382-388.
16. Chan-Yeung M, Ferguson A, Watson W, et al. The Canadian childhood asthma primary prevention study: outcomes at 7 years of age. J Allergy Clin Immunol. 2005;116:49-55.
17. Bertelsen RJ, Carlsen KC, Carlsen KH, et al. Childhood asthma and early life exposure to indoor allergens, endotoxin and β(1,3)-glucans. Clin Exp Allergy. 2010;40:307-316.
18. Collin SM, Granell R, Westgarth C, et al. Associations of Pet Ownership with Wheezing and Lung Function in Childhood: findings from a UK Birth Cohort. PLoS ONE. 2015;10:e0127756.
19. Dong GH, Qian ZM, Liu MM, et al. Breastfeeding as a modifier of the respiratory effects of air pollution in children. Epidemiology. 2013;24:387-394.
20. Dong GH, Qian ZM, Wang J, et al. Home renovation, family history of atopy, and respiratory symptoms and asthma among children living in China. Am J Public Health. 2014;104:1920-1927.
21. Qian Z, Dong G-H, Ren W-H, et al. Effect of pet ownership on respiratory responses to air pollution in Chinese children: the Seven Northeastern Cities (SNEC) study. Atmos Environ 2014;87:47-52.
22. Dong GH, Qian Z, Liu MM, et al. Obesity enhanced respiratory health effects of ambient air pollution in Chinese children: the Seven Northeastern Cities study. Int J Obes. 2013;37:94-100.
23. Dong G-H, Qian Z, Liu M-M, et al. Ambient air pollution and the prevalence of obesity in chinese children: the Seven Northeastern Cities study. Obesity. 2014;22:795-800.
24. Dong GH, Qian ZM, Wang J, et al. Residential characteristics and household risk factors and respiratory diseases in Chinese women: the Seven Northeast Cities (SNEC) study. Sci Total Environ. 2013;463–464:389-394.
25. Dong GH, Qian Z, Fu Q, et al. A Multiple Indicators Multiple Cause (MIMIC) model of respiratory health and household factors in Chinese children: the Seven Northeastern Cities (SNEC) study. Matern Child Health J. 2014;18:129-137.
26. Wang D, Qian Z, Wang J, et al. Gender-specific differences in associations of overweight and obesity with asthma and asthma-related symptoms in 30 056 children: results from 25 districts of Northeastern China. J Asthma. 2014;51:508-514.
27. Dong GH, Wang J, Liu MM, Wang D, Lee YL, Zhao YD. Allergic predisposition modifies the effects of pet exposure on respiratory disease in boys and girls: the Seven Northeast Cities of China (SNECC) study. Environ Health. 2012;11:50.
28. Zeng XW, Qian ZM, Vaughn MG, et al. Positive association between short-term ambient air pollution exposure and children blood pressure in China -Results from the Seven Northeast Cities (SNEC) study. Environ Pollut. 2017;224:698-705.
29. Xu SL, Trevathan E, Qian Z, et al. Prenatal and postnatal exposure to pet ownership, blood pressure and hypertension in children: the Seven Northeastern Cities study. J Hypertens. 2017;35:259-265.
30. Zeng X-W, Vivian E, Mohammed KA, et al. Long-term ambient air pollution and lung function impairment in Chinese children from a high air pollution range area: the Seven Northeastern Cities (SNEC) study. Atmos Environ. 2016;138:144-151.
31. Dong GH, Wang J, Zeng XW, et al. Interactions between air pollution and obesity on blood pressure and hypertension in Chinese children. Epidemiology. 2015;26:740-747.
32. Dong GH, Qian ZM, Trevathan E, et al. Air pollution associated hypertension and increased blood pressure may be reduced by breastfeeding in Chinese children: the Seven Northeastern Cities Chinese Children's Study. Int J Cardiol. 2014;176:956-961.
33. Yuan P, Qian ZM, Vaughn M, et al. Comparison of body mass index with abdominal obesity for identifying elevated blood pressure in children and adolescents: the SNEC study. Obes Res Clin Pract. 2016. https://doi.org/10.1016/j.orcp.2016.08.006.
34. Mehrparvar AH, Sakhvidi MJ, Mostaghaci M, et al. Spirometry values for detecting a restrictive pattern in occupational health settings. Tanaffos. 2014;13:27-34.
35. Ma YN, Wang J, Dong GH, et al. Predictive equations using regression analysis of pulmonary function for healthy children in Northeast China. PLoS ONE. 2013;8:e63875.
36. Beasley R, Semprini A, Mitchell EA. Risk factors for asthma: is prevention possible? Lancet. 2015;386:1075-1085.
37. Brunekreef B, Von Mutius E, Wong G, et al. Exposure to cats and dogs, and symptoms of asthma, rhinoconjunctivitis, and eczema. Epidemiology. 2012;23:742-750.
38. Dick S, Doust E, Cowie H, Ayres JG, Turner S. Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review. BMJ Open 2014;4:e003827.
39. Eldeirawi K, Kunzweiler C, Combs AM, Persky VW. In utero exposure to pets is associated with asthma and wheezing in Mexican American children. J Asthma. 2016;53:374-381.
40. Lodge CJ, Lowe AJ, Gurrin LC, et al. Pets at birth do not increase allergic disease in at-risk children. Clin Exp Allergy. 2012;42:1377-1385.
41. Takkouche B, González-Barcala FJ, Etminan M, Fitzgerald M. Exposure to furry pets and the risk of asthma and allergic rhinitis: a meta-analysis. Allergy. 2008;63:857-864.
42. Carlsten C, Brauer M, Dimich-Ward H, et al. Combined exposure to dog and indoor pollution: incident asthma in a high-risk birth cohort. Eur Respir J. 2011;37:324-330.
43. Ingram JM, Sporik R, Rose G, et al. Quantitative assessment of exposure to dog (Canf1) and cat (Feld1) allergen: relation to sensitization and asthma among children living in Los Alamos, New Mexico. J Allergy Clin Immunol. 1995;96:449-456.
44. Stevenson MD, Sellins S, Grube E, et al. Aeroallergen sensitization in healthy children: racial and socioeconomic correlates. J Pediatr. 2007;151:187-191.
45. Sandin A, Björkstén B, Bråbäck L. Development of atopy and wheezing symptoms in relation to heredity and early pet keeping in a Swedish birth cohort. Pediatr Allergy Immunol. 2004;15:316-322.
46. Lau S, Wickman M. Indoor Allergen Exposure: Allergy, Immunity and Tolerance in Early Childhood. London, UK: Academic Press; 2016.
47. Thorne PS, Cohn RD, Mav D, et al. Predictors of endotoxin levels in U.S. housing. Environ Health Perspect. 2009;117:763-771.
48. El Sharif N, Douwes J, Hoet PH, et al. Concentrations of domestic mite and pet allergens and endotoxin in Palestine. Allergy. 2004;59:623-631.
49. Gereda JE, Klinnert MD, Price MR, et al. Metropolitan home living conditions associated with indoor endotoxin levels. J Allergy Clin Immunol. 2001;107:790-796.
50. Gehring U, Bischof W, Borte M, et al. Levels and predictors of endotoxin in mattress dust samples from East and West German homes. Indoor Air. 2004;14:284-292.
51. Platts-Mills JA, Custis NJ, Woodfolk JA, Platts-Mills TA. Airborne endotoxin in homes with domestic animals: implications for cat-specific tolerance. J Allergy Clin Immunol. 2005;116:384-389.
52. Waser M, von Mutius E, Riedler J, et al. Exposure to pets, and the association with hay fever, asthma, and atopic sensitization in rural children. Allergy. 2005;60:177-184.
53. Alexis NE, Lay JC, Almond M, Peden DB. Inhalation of low-dose endotoxin favors local TH2 response and primes airway phagocytes in vivo. J Allergy Clin Immunol. 2004;114:1325-1331.
54. Alexis NE, Lay JC, Almond M, et al. Acute LPS inhalation in healthy volunteers induces dendritic cell maturation in vivo. J Allergy Clin Immunol. 2005;115:345-350.
55. Möller W, Heimbeck I, Hofer TP, et al. Differential inflammatory response to inhaled lipopolysaccharide targeted either to the airways or the alveoli in man. PLoS ONE. 2012;7:e33505.
56. Gereda JE, Leung DY, Thatayatikom A, et al. Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma. Lancet. 2000;355:1680-1683.
57. Lappalainen MH, Huttunen K, Roponen M, et al. Exposure to dogs is associated with a decreased tumour necrosis factor-α-producing capacity in early life. Clin Exp Allergy. 2010;40:1498-1506.
58. von Mutius E, Braun-Fahrländer C, Schierl R, et al. Exposure to endotoxin or other bacterial components might protect against the development of atopy. Clin Exp Allergy. 2000;30:1230-1234.
59. Chen CM, Thiering E, Doekes G, et al. Geographical variation and the determinants of domestic endotoxin levels in mattress dust in Europe. Indoor Air. 2012;22:24-32.
60. Dassonville C, Demattei C, Vacquier B, et al. Indoor airborne exdotoxin assessment in homes of Paris newborn babies. Indoor Air. 2008;18:480-487.
61. Ownby DR, Peterson EL, Wegienka G, et al. Are cats and dogs the major source of endotoxin in homes? Indoor Air. 2013;23:219-226.
62. Grobeis Marketing Research. Dalian pet beauty market survey report. Dalian, China, 2015. (in Chinese).
63. Hodson T, Custovic A, Simpson A, et al. Washing the dog reduces dog allergen levels, but the dog needs to be washed twice a week. J Allergy Clin Immunol. 1999;103:581-585.
64. Clougherty JE, Kubzansky LD. A framework for examining social stress and susceptibility to air pollution in respiratory health. Environ Health Perspect. 2009;117:1351-1358.
65. Gold DR, Wypij D, Wang X, et al. Gender- and race-specific effects of asthma and wheeze on level and growth of lung function in children in six U.S. cities. Am J Respir Crit Care Med. 1994;149:1198-1208.
66. Peters EJ, Esin RA, Immananagha KK, Siziya S, Osim EE. Lung function status of some Nigerian men and women chronically exposed to fish drying using burning firewood. Cent Afr J Med. 1999;45:119-124.
67. Forno E, Han YY, Muzumdar RH, Celedón JC. Insulin resistance, metabolic syndrome, and lung function in US adolescents with and without asthma. J Allergy Clin Immunol. 2015;136:304-311.
68. Frey U, Latzin P, Usemann J, et al. Asthma and obesity in children: current evidence and potential systems biology approaches. Allergy. 2015;70:26-40.
69. Oftedal B, Brunekreef B, Nystad W, et al. Residential outdoor air pollution and lung function in schoolchildren. Epidemiology. 2008;19:129-137.
70. Langley SJ, Goldthorpe S, Craven M, et al. Exposure and sensitization to indoor allergens: association with lung function, bronchial reactivity, and exhaled nitric oxide measures in asthma. J Allergy Clin Immunol. 2003;112:362-368.
71. Plaschke P, Janson C, Balder B, et al. Adult asthmatics sensitized to cats and dogs: symptoms, severity, and bronchial hyperresponsiveness in patients with furred animals at home and patients without these animals. Allergy. 1999;54:843-850.
72. Asarnoj A, Hamsten C, Wadén K, et al. Sensitization to cat and dog allergen molecules in childhood and prediction of symptoms of cat and dog allergyin adolescence: a BAMSE/MeDALL study. J Allergy Clin Immunol. 2016;137:813-821.
73. Oczypok EA, Milutinovic PS, Alcorn JF, et al. Pulmonary receptor for advanced glycation end-products promotes asthma pathogenesis through IL-33 and accumulation of group 2 innate lymphoid cells. J Allergy Clin Immunol. 2015;136:747-756.
74. Osterlund C, Grönlund H, Gafvelin G, Bucht A. Non-proteolytic aeroallergens from mites, cat and dog exert adjuvant-like activation of bronchial epithelial cells. Int Arch Allergy Immunol. 2011;155:111-118.
75. Parvaneh S, Kronqvist M, Johansson E, van Hage-Hamsten M. Exposure to an abundance of cat (Fel d 1) and dog (Can f 1) allergens in Swedish farming households. Allergy. 1999;54:229-234.
76. Saarne T, Grönlund H, Kull I, Almqvist C, Wickman M, van Hage M. Cat sensitization identified by recombinant Feld1 several years before symptoms–results from the BAMSE cohort. Pediatr Allergy Immunol. 2010;21:277-283.
77. Martinez-Gonzalez I, Steer CA, Takei F. Lung ILC2s link innate and adaptive responses in allergic inflammation. Trends Immunol. 2015;36:189-195.
78. Poulsen LK, Hummelshoj L. Triggers of IgE class switching and allergy development. Ann Med. 2007;39:440-456.
79. Wedemeyer J, Tsai M, Galli SJ. Roles of mast cells and basophils in innate and acquired immunity. Curr Opin Immunol. 2000;12:624-631.
80. Wan H, Winton HL, Soeller C, et al. Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions. J Clin Invest. 1999;104:123-133.
81. Moro K, Yamada T, Tanabe M, et al. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(1)Sca-1(1) lymphoid cells. Nature. 2010;463:540-544.
82. Barlow JL, Peel S, Fox J, et al. IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction. J Allergy Clin Immunol. 2013;132:933-941.
83. Andreasen AS, Krabbe KS, Krogh-Madsen R. Human endotoxemia as a model of systemic inflammation. Curr Med Chem. 2008;15:1697-1705.
84. Derocq JM, Bourrié B, Ségui M, et al. In vivo inhibition of endotoxin- induced pro-inflammatory cytokines production by the sigma ligand SR 31747. J Pharmacol Exp Ther. 1995;272:224-230.
85. Wickens K, Douwes J, Siebers R, et al. Determinants of endotoxin levels in carpets in New Zealand homes. Indoor Air. 2003;13:128-135.
86. Donham KJ, Cumro D, Reynolds SJ, Merchant JA. Dose-response relationships between occupational aerosol exposures and cross-shift declines of lung function in poultry workers: recommendations for exposure limits. J Occup Environ Med. 2000;42:260-269.
87. Schneberger D, Aulakh G, Channabasappa S, Singh B. Toll-like receptor 9 partially regulates lung inflammation induced following exposure to chicken barn air. J Occup Med Toxicol. 2016;11:31.
88. Vogelzang PF, van der Gulden JW, Folgering H, et al. Endotoxin exposure as a major determinant of lung function decline in pig farmers. Am J Respir Crit Care Med. 1998;157:15-18.
89. Fretzayas A, Kotzia D, Moustaki M. Controversial role of pets in the development of atopy in children. World J Pediatr. 2013;9:112-119.
90. Min KB, Min JY. Exposure to household endotoxin and total and allergen-specific IgE in the US population. Environ Pollut. 2015;199:148-154.
91. Zhai L, Dong Y, Bai Y, Wei W, Jia L. Trends in obesity, overweight, and malnutrition among children and adolescents in Shenyang, China in 2010 and 2014: a multiple cross-sectional study. BMC Public Health. 2017;17:151.
92. Wijnhoven TM, van Raaij JM, Yngve A, et al. WHO European Childhood Obesity Surveillance Initiative: health-risk behaviours on nutrition and physical activity in 6-9-year-old schoolchildren. Public Health Nutr. 2015;18:3108-3124.