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Volumn 239, Issue , 2018, Pages 268-275

Monitoring protein hydrolysis by pepsin using pH-stat: In vitro gastric digestions in static and dynamic pH conditions

Author keywords

Aspartic proteases; Hydrolysis; In vitro digestion; Pepsin; pH stat; Proteolysis; Titrimetry; Whey proteins

Indexed keywords

BIOLOGICAL MATERIALS; HYDROLYSIS; PH; PROTEOLYSIS;

EID: 85021212541     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2017.06.115     Document Type: Article
Times cited : (70)

References (32)
  • 2
    • 84985222644 scopus 로고
    • Effects of in vitro proteolysis on the allergenicity of major whey proteins
    • Asselin, J., Hébert, J., Amiot, J., Effects of in vitro proteolysis on the allergenicity of major whey proteins. Journal of Food Science 54 (1989), 1037–1039.
    • (1989) Journal of Food Science , vol.54 , pp. 1037-1039
    • Asselin, J.1    Hébert, J.2    Amiot, J.3
  • 3
    • 0029764078 scopus 로고    scopus 로고
    • Stability of food allergens to digestion in vitro
    • Astwood, J.D., Leach, J.N., Fuchs, R.L., Stability of food allergens to digestion in vitro. Nature Biotechnology 14 (1996), 1269–1273.
    • (1996) Nature Biotechnology , vol.14 , pp. 1269-1273
    • Astwood, J.D.1    Leach, J.N.2    Fuchs, R.L.3
  • 6
    • 0022966980 scopus 로고
    • Comparison of canine and human gastrointestinal physiology
    • Dressman, J.B., Comparison of canine and human gastrointestinal physiology. Pharmaceutical Research 3 (1986), 123–131.
    • (1986) Pharmaceutical Research , vol.3 , pp. 123-131
    • Dressman, J.B.1
  • 7
    • 0037145909 scopus 로고    scopus 로고
    • Digestibility of food allergens and nonallergenic proteins in simulated gastric fluid and simulated intestinal fluid – A comparative study
    • Fu, T.J., Abbott, U.R., Hatzos, C., Digestibility of food allergens and nonallergenic proteins in simulated gastric fluid and simulated intestinal fluid – A comparative study. Journal of Agricultural and Food Chemistry 50 (2002), 7154–7160.
    • (2002) Journal of Agricultural and Food Chemistry , vol.50 , pp. 7154-7160
    • Fu, T.J.1    Abbott, U.R.2    Hatzos, C.3
  • 9
    • 85049379632 scopus 로고    scopus 로고
    • Crash course: Gastrointestinal system
    • 4th ed. MOSBY Elsevier
    • Griffiths, M., Crash course: Gastrointestinal system. 4th ed., 2012, MOSBY Elsevier.
    • (2012)
    • Griffiths, M.1
  • 11
    • 0029398314 scopus 로고
    • Susceptibility of β-lactoglobulin and sodium caseinate to proteolysis by pepsin and trypsin
    • Guo, M.R., Fox, P.F., Flynn, A., Kindstedt, P.S., Susceptibility of β-lactoglobulin and sodium caseinate to proteolysis by pepsin and trypsin. Journal of Dairy Science 78 (1995), 2336–2344.
    • (1995) Journal of Dairy Science , vol.78 , pp. 2336-2344
    • Guo, M.R.1    Fox, P.F.2    Flynn, A.3    Kindstedt, P.S.4
  • 12
    • 34848859979 scopus 로고    scopus 로고
    • Peptic and tryptic hydrolysis of native and heated whey protein to reduce its antigenicity
    • Kim, S.B., Ki, K.S., Khan, M.A., Lee, W.S., Lee, H.J., Ahn, B.S., Kim, H.S., Peptic and tryptic hydrolysis of native and heated whey protein to reduce its antigenicity. Journal of Dairy Science 90 (2007), 4043–4050.
    • (2007) Journal of Dairy Science , vol.90 , pp. 4043-4050
    • Kim, S.B.1    Ki, K.S.2    Khan, M.A.3    Lee, W.S.4    Lee, H.J.5    Ahn, B.S.6    Kim, H.S.7
  • 13
    • 0000420114 scopus 로고    scopus 로고
    • Digestibility of bovine milk whey protein and β-lactoglobulin in vitro and in vivo
    • Kitabatake, N., Kinekawa, Y.I., Digestibility of bovine milk whey protein and β-lactoglobulin in vitro and in vivo. Journal of Agricultural and Food Chemistry 46 (1998), 4917–4923.
    • (1998) Journal of Agricultural and Food Chemistry , vol.46 , pp. 4917-4923
    • Kitabatake, N.1    Kinekawa, Y.I.2
  • 14
    • 84894725094 scopus 로고    scopus 로고
    • Impact of the dairy matrix structure on milk protein digestion kinetics: Mechanistic modelling based on mini-pig in vivo data
    • Le Feunteun, S., Barbé, F., Remond, D., Ménard, O., Le Gouar, Y., Dupont, D., Laroche, B., Impact of the dairy matrix structure on milk protein digestion kinetics: Mechanistic modelling based on mini-pig in vivo data. Food and Bioprocess Technology 7 (2014), 1099–1113.
    • (2014) Food and Bioprocess Technology , vol.7 , pp. 1099-1113
    • Le Feunteun, S.1    Barbé, F.2    Remond, D.3    Ménard, O.4    Le Gouar, Y.5    Dupont, D.6    Laroche, B.7
  • 15
    • 0018356554 scopus 로고
    • Different gastric, pancreatic, and biliary responses to solid-liquid or homogenized meals
    • Malagelada, J.-R., Go, V.L.W., Summerskill, W.H.J., Different gastric, pancreatic, and biliary responses to solid-liquid or homogenized meals. Digestive Diseases and Sciences 24 (1979), 101–110.
    • (1979) Digestive Diseases and Sciences , vol.24 , pp. 101-110
    • Malagelada, J.-R.1    Go, V.L.W.2    Summerskill, W.H.J.3
  • 16
    • 84876804316 scopus 로고    scopus 로고
    • Relationships between gastric emptying, postprandial glycemia, and incretin hormones
    • Marathe, C.S., Rayner, C.K., Jones, K.L., Horowitz, M., Relationships between gastric emptying, postprandial glycemia, and incretin hormones. Diabetes Care 36:5 (2013), 1396–1405.
    • (2013) Diabetes Care , vol.36 , Issue.5 , pp. 1396-1405
    • Marathe, C.S.1    Rayner, C.K.2    Jones, K.L.3    Horowitz, M.4
  • 17
    • 84960870936 scopus 로고    scopus 로고
    • In vitro digestion of foods using pH-stat and the INFOGEST protocol: Impact of matrix structure on digestion kinetics of macronutrients, proteins and lipids
    • Mat, D.J.L., Le Feunteun, S., Michon, C., Souchon, I., In vitro digestion of foods using pH-stat and the INFOGEST protocol: Impact of matrix structure on digestion kinetics of macronutrients, proteins and lipids. Food Research International 88 (2016), 226–233.
    • (2016) Food Research International , vol.88 , pp. 226-233
    • Mat, D.J.L.1    Le Feunteun, S.2    Michon, C.3    Souchon, I.4
  • 18
    • 78049289421 scopus 로고    scopus 로고
    • Structured emulsion-based delivery systems: Controlling the digestion and release of lipophilic food components
    • McClements, D.J., Li, Y., Structured emulsion-based delivery systems: Controlling the digestion and release of lipophilic food components. Advances in Colloid and Interface Science 159 (2010), 213–228.
    • (2010) Advances in Colloid and Interface Science , vol.159 , pp. 213-228
    • McClements, D.J.1    Li, Y.2
  • 20
    • 84901667773 scopus 로고    scopus 로고
    • A standardised static in vitro digestion method suitable for food – An international consensus
    • Minekus, M., Alminger, M., Alvito, P., Ballance, S., Bohn, T., Bourlieu, C.,. Brodkorb, A., A standardised static in vitro digestion method suitable for food – An international consensus. Food & Function 5 (2014), 1113–1124.
    • (2014) Food & Function , vol.5 , pp. 1113-1124
    • Minekus, M.1    Alminger, M.2    Alvito, P.3    Ballance, S.4    Bohn, T.5    Bourlieu, C.6    Brodkorb, A.7
  • 21
    • 85052696733 scopus 로고    scopus 로고
    • Functionality of protein hydrolysates
    • S. Damodaran A. Paraf CRC Press
    • Nielsen, M., Functionality of protein hydrolysates. Damodaran, S., Paraf, A., (eds.) Food proteins and their applications, 1997, CRC Press, 443–472.
    • (1997) Food proteins and their applications , pp. 443-472
    • Nielsen, M.1
  • 23
    • 0013806544 scopus 로고
    • PH stability and activity curves of pepsin with special reference to their clinical importance
    • Piper, D.W., Fenton, B.H., PH stability and activity curves of pepsin with special reference to their clinical importance. Gut 6 (1965), 506–508.
    • (1965) Gut , vol.6 , pp. 506-508
    • Piper, D.W.1    Fenton, B.H.2
  • 25
    • 0042553279 scopus 로고
    • Smoothing and differentiation of data by simplified least squares procedures
    • Savitzky, A., Golay, M.J.E., Smoothing and differentiation of data by simplified least squares procedures. Analytical Chemistry 36 (1964), 1627–1639.
    • (1964) Analytical Chemistry , vol.36 , pp. 1627-1639
    • Savitzky, A.1    Golay, M.J.E.2
  • 26
    • 0038029531 scopus 로고    scopus 로고
    • Proteinase and exopeptidase hydrolysis of whey protein: Comparison of the TNBS, OPA and pH stat methods for quantification of degree of hydrolysis
    • Spellman, D., McEvoy, E., O'Cuinn, G., FitzGerald, R.J., Proteinase and exopeptidase hydrolysis of whey protein: Comparison of the TNBS, OPA and pH stat methods for quantification of degree of hydrolysis. International Dairy Journal 13 (2003), 447–453.
    • (2003) International Dairy Journal , vol.13 , pp. 447-453
    • Spellman, D.1    McEvoy, E.2    O'Cuinn, G.3    FitzGerald, R.J.4
  • 27
    • 0038203869 scopus 로고
    • Comparaison de trois méthodes pour la mesure du degré d'hydrolyse de protéines laitières modifiées enzymatiquement
    • Turgeon, S.L., Bard, C., Gauthier, S.F., Comparaison de trois méthodes pour la mesure du degré d'hydrolyse de protéines laitières modifiées enzymatiquement. Canadian Institute of Food Science and Technology Journal 24 (1991), 14–18.
    • (1991) Canadian Institute of Food Science and Technology Journal , vol.24 , pp. 14-18
    • Turgeon, S.L.1    Bard, C.2    Gauthier, S.F.3
  • 28
    • 0017272560 scopus 로고
    • Structures and activities of protease inhibitors of microbial origin
    • Umezawa, H., Structures and activities of protease inhibitors of microbial origin. Methods in Enzymology 45 (1976), 678–695.
    • (1976) Methods in Enzymology , vol.45 , pp. 678-695
    • Umezawa, H.1
  • 29
    • 11844280172 scopus 로고
    • Buffer intensities of milk and milk constituents I. The buffer action of casein in milk
    • Whittier, E.O., Buffer intensities of milk and milk constituents I. The buffer action of casein in milk. Journal of Biological Chemistry 83 (1929), 79–88.
    • (1929) Journal of Biological Chemistry , vol.83 , pp. 79-88
    • Whittier, E.O.1
  • 30
    • 69149106437 scopus 로고    scopus 로고
    • In vitro digestion methods for assessing the effect of food structure on allergen breakdown
    • Wickham, M., Faulks, R., Mills, C., In vitro digestion methods for assessing the effect of food structure on allergen breakdown. Molecular Nutrition & Food Research 53 (2009), 952–958.
    • (2009) Molecular Nutrition & Food Research , vol.53 , pp. 952-958
    • Wickham, M.1    Faulks, R.2    Mills, C.3
  • 31
    • 84864051006 scopus 로고    scopus 로고
    • Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations
    • Williams, H.D., Sassene, P., Kleberg, K., Bakala-N'Goma, J.-C., Calderone, M., Jannin, V.,. Pouton, C.W., Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations. Journal of Pharmaceutical Sciences 101 (2012), 3360–3380.
    • (2012) Journal of Pharmaceutical Sciences , vol.101 , pp. 3360-3380
    • Williams, H.D.1    Sassene, P.2    Kleberg, K.3    Bakala-N'Goma, J.-C.4    Calderone, M.5    Jannin, V.6    Pouton, C.W.7
  • 32
    • 84885344193 scopus 로고    scopus 로고
    • Impact of different biopolymer networks on the digestion of gastric structured emulsions
    • Wooster, T.J., Day, L., Xu, M., Golding, M., Oiseth, S., Keogh, J., Clifton, P.M., Impact of different biopolymer networks on the digestion of gastric structured emulsions. Food Hydrocolloids 36 (2014), 102–114.
    • (2014) Food Hydrocolloids , vol.36 , pp. 102-114
    • Wooster, T.J.1    Day, L.2    Xu, M.3    Golding, M.4    Oiseth, S.5    Keogh, J.6    Clifton, P.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.