Exposure to particulate matter 2.5 (PM2.5) induced macrophage-dependent inflammation, characterized by increased Th1/Th17 cytokine secretion and cytotoxicity

International Immunopharmacology

Volumn 50, Issue , 2017, Pages 139-145

  Ma, Qin Yun ^a   Huang, Da Yu ^a   Zhang, Hui Jun ^a   Wang, Shaohua ^a   Chen, Xiao Feng ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Macrophage; PM2.5; Th1; Th17

Indexed keywords

GAMMA INTERFERON; GRANZYME A; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 4; MESSENGER RNA; INTERLEUKIN DERIVATIVE;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOLYSIS; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MONOCYTE; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; UPREGULATION; ANTIGEN PRESENTATION; APOPTOSIS; BRONCHUS; CELL CULTURE; EPITHELIUM CELL; IMMUNOLOGY; METABOLISM; PATHOLOGY;

ANTIGEN PRESENTATION; APOPTOSIS; BRONCHI; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; EPITHELIAL CELLS; HUMANS; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKINS; MACROPHAGES; PARTICULATE MATTER; TH1 CELLS; TH17 CELLS;

EID: 85021167270     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2017.06.019     Document Type: Article

References (38)

1. Siegel, R., Naishadham, D., Jemal, A., Cancer statistics, 2013. CA Cancer J. Clin. 63 (2013), 11–30, 10.3322/caac.21166.
2. Weichenthal, S.A., Godri-Pollitt, K., Villeneuve, P.J., PM2.5, oxidant defence and cardiorespiratory health: a review. Environ. Health, 12(40), 2013, 10.1186/1476-069X-12-40.
3. Pope, C.A. III, Burnett, R.T., Thun, M.J., Calle, E.E., Krewski, D., Ito, K. et al., Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA 287 (2002), 1132–1141, 10.1001/jama.287.9.1132.
4. Duan, M.-C., Zhong, X.-N., Liu, G.-N., Wei, J.-R., The Treg/Th17 paradigm in lung cancer. J. Immunol. Res., 2014, 730380–(2014)730389, 10.1155/2014/730380.
5. Block, M.L., Calderón-Garcidueñas, L., Air pollution: mechanisms of neuroinflammation and CNS disease. Trends Neurosci. 32 (2009), 506–516, 10.1016/j.tins.2009.05.009.
6. Xing, Y.-F., Xu, Y.-H., Shi, M.-H., Lian, Y.-X., The impact of PM2.5 on the human respiratory system. J. Thorac. Dis. 8 (2016), E69–E74, 10.3978/j.issn.2072-1439.2016.01.19.
7. Turner, M.C., Krewski, D., Pope, C.A., Chen, Y., Gapstur, S.M., Thun, M.J., Long-term ambient fine particulate matter air pollution and lung cancer in a large cohort of never-smokers. Am. J. Respir. Crit. Care Med. 184 (2011), 1374–1381, 10.1164/rccm.201106-1011OC.
8. Lee, G., Walser, T.C., Dubinett, S.M., Chronic inflammation, chronic obstructive pulmonary disease, and lung cancer. Curr. Opin. Pulm. Med. 15 (2009), 303–307, 10.1097/MCP.0b013e32832c975a.
9. Greenwell, L.L., Moreno, T., Jones, T.P., Richards, R.J., Particle-induced oxidative damage is ameliorated by pulmonary antioxidants. Free Radic. Biol. Med. 32 (2002), 898–905.
10. Valavanidis, A., Fiotakis, K., Bakeas, E., Vlahogianni, T., Electron paramagnetic resonance study of the generation of reactive oxygen species catalysed by transition metals and quinoid redox cycling by inhalable ambient particulate matter. Redox Rep. 10 (2005), 37–51, 10.1179/135100005X21606.
11. Park, E.-J., Roh, J., Kim, Y., Park, K., Kim, D.-S., Yu, S.-D., PM 2.5 collected in a residential area induced Th1-type inflammatory responses with oxidative stress in mice. Environ. Res. 111 (2011), 348–355, 10.1016/j.envres.2010.11.001.
12. Martinez, F.O., Gordon, S., The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep., 6(13), 2014, 10.12703/P6-13.
13. Italiani, P., Boraschi, D., From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation. Front. Immunol., 5(514), 2014, 10.3389/fimmu.2014.00514.
14. He, M., Ichinose, T., Yoshida, S., Nishikawa, M., Mori, I., Yanagisawa, R. et al., Urban particulate matter in Beijing, China, enhances allergen-induced murine lung eosinophilia. Inhal. Toxicol. 22 (2010), 709–718, 10.3109/08958371003631608.
15. Yoshizaki, K., Brito, J.M., Toledo, A.C., Nakagawa, N.K., Piccin, V.S., Junqueira, M.S. et al., Subchronic effects of nasally instilled diesel exhaust particulates on the nasal and airway epithelia in mice. Inhal. Toxicol. 22 (2010), 610–617, 10.3109/08958371003621633.
16. Imrich, A., Ning, Y., Kobzik, L., Insoluble components of concentrated air particles mediate alveolar macrophage responses in vitro. Toxicol. Appl. Pharmacol. 167 (2000), 140–150, 10.1006/taap.2000.9002.
17. Liu, F., Huang, Y., Zhang, F., Chen, Q., Wu, B., Rui, W. et al., Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation. J. Neurochem., 134, 2015, 10.1111/jnc.13135 (315–26).
18. Hombach, A., Köhler, H., Rappl, G., Abken, H., Human CD4 + T cells lyse target cells via granzyme/perforin upon circumvention of MHC class II restriction by an antibody-like immunoreceptor. J. Immunol. 177 (2006), 5668–5675, 10.4049/jimmunol.177.8.5668.
19. Trenn, G., Takayama, H., Sitkovsky, M.V., Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes. Nature 330 (1987), 72–74, 10.1038/330072a0.
20. Ostergaard, H.L., Kane, K.P., Mescher, M.F., Clark, W.R., Cytotoxic T lymphocyte mediated lysis without release of serine esterase. Nature 330 (1987), 71–72, 10.1038/330071a0.
21. Fu, J., Zhang, Z., Zhou, L., Qi, Z., Xing, S., Lv, J. et al., Impairment of CD4 + cytotoxic T cells predicts poor survival and high recurrence rates in patients with hepatocellular carcinoma. Hepatology 58 (2013), 139–149, 10.1002/hep.26054.
22. Maini, M.K., Boni, C., Lee, C.K., Larrubia, J.R., Reignat, S., Ogg, G.S. et al., The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection. J. Exp. Med. 191 (2000), 1269–1280, 10.1084/jem.191.8.1269.
23. He, R., Hou, S., Liu, C., Zhang, A., Bai, Q., Han, M. et al., Follicular CXCR5-expressing CD8(+) T cells curtail chronic viral infection. Nature, 2016, 1–20, 10.1038/nature19317.
24. Thimme, R., Wieland, S., Steiger, C., Ghrayeb, J., Reimann, K.A., Purcell, R.H. et al., CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. J. Virol. 77 (2003), 68–76, 10.1128/JVI.77.1.68-76.2003.
25. Kasaian, M.T., Whitters, M.J., Carter, L.L., Lowe, L.D., Jussif, J.M., Deng, B. et al., IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Immunity 16 (2002), 559–569, 10.1016/S1074-7613(02)00295-9.
26. Hadrup, S., Donia, M., Thor Straten, P., Effector CD4 and CD8 T cells and their role in the tumor microenvironment. Cancer Microenviron., 6, 2013, 10.1007/s12307-012-0127-6 (123–33).
27. Nguyen, H.H., Kim, T., Song, S.Y., Park, S., Cho, H.H., Jung, S.-H. et al., Naïve CD8 + T cell derived tumor-specific cytotoxic effectors as a potential remedy for overcoming TGF-β immunosuppression in the tumor microenvironment. Sci Rep, 6, 2016, 28208, 10.1038/srep28208.
28. Chen, Z.-H., Wu, Y.-F., Wang, P.-L., Wu, Y.-P., Li, Z.-Y., Zhao, Y. et al., Autophagy is essential for ultrafine particle-induced inflammation and mucus hyperproduction in airway epithelium. Autophagy 12 (2016), 297–311, 10.1080/15548627.2015.1124224.
29. Wigle, D.A., Jurisica, I., Radulovich, N., Pintilie, M., Rossant, J., Liu, N. et al., Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Res. 62 (2002), 3005–3008.
30. Bevan, M.J., Helping the CD8 + T-cell response. Nat. Rev. Immunol. 4 (2004), 595–602, 10.1038/nri1413.
31. Phares, T.W., Stohlman, S.A., Hwang, M., Min, B., Hinton, D.R., Bergmann, C.C., CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis. J. Virol. 86 (2012), 2416–2427, 10.1128/JVI.06797-11.
32. Korn, T., Bettelli, E., Oukka, M., Kuchroo, V.K., IL-17 and Th17 cells. Annu. Rev. Immunol. 27 (2009), 485–517, 10.1146/annurev.immunol.021908.132710.
33. Reppert, S., Boross, I., Koslowski, M., Türeci, Ö., Koch, S., Lehr, H.A. et al., A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer. Nat. Commun., 2, 2011, 600, 10.1038/ncomms1609.
34. Coquet, J.M., Skak, K., Davis, I.D., Smyth, M.J., Godfrey, D.I., IL-21 modulates activation of NKT cells in patients with stage IV malignant melanoma. Clin. Transl. Immunol., 2, 2013, e6, 10.1038/cti.2013.7.
35. Trandem, K., Zhao, J., Fleming, E., Perlman, S., Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis. J. Immunol. 186 (2011), 3642–3652, 10.4049/jimmunol.1003292.
36. Emmerich, J., Mumm, J.B., Chan, I.H., LaFace, D., Truong, H., McClanahan, T. et al., IL-10 directly activates and expands tumor-resident CD8 + T cells without de novo infiltration from secondary lymphoid organs. Cancer Res. 72 (2012), 3570–3581, 10.1158/0008-5472.CAN-12-0721.
37. Acosta-Rodriguez, E.V., Napolitani, G., Lanzavecchia, A., Sallusto, F., Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol. 8 (2007), 942–949, 10.1038/ni1496.
38. Jones, K.D., Aoki, Y., Chang, Y., Moore, P.S., Yarchoan, R., Tosato, G., Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi's sarcoma herpesvirus-associated infected primary effusion lymphoma cells. Blood 94 (1999), 2871–2879.