Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing

Acta Neuropathologica

Volumn 134, Issue 5, 2017, Pages 691-703

  Euskirchen, Philipp ^a,b,c   Bielle, Franck ^a,d,e   Labreche, Karim ^a,f   Kloosterman, Wigard P ^g   Rosenberg, Shai ^a   Daniau, Mailys ^a   Schmitt, Charlotte ^a   Masliah Planchon, Julien ^h   Bourdeaut, Franck ^h   Dehais, Caroline ^d   Marie, Yannick ^a   Delattre, Jean Yves ^a,d   Idbaih, Ahmed ^a,d  

^a SORBONNE UNIVERSITÉ   (France)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c BERLIN INSTITUTE OF HEALTH   (Germany)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e Onconeurotek   (France)

^f INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^g UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^h INSTITUT CURIE   (France)

Author keywords

Brain tumor; Epigenomics; Glioma; Molecular neuropathology; Nanopore sequencing; Whole genome sequencing

Indexed keywords

ADULT; AGED; AMPLICON; ARTICLE; BRAIN METASTASIS; BRAIN TUMOR; CANCER CLASSIFICATION; CHILD; CLINICAL ARTICLE; COPY NUMBER VARIATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE AMPLIFICATION; GENOMICS; GLIOMA; HUMAN; MALE; MEDULLOBLASTOMA; MIDDLE AGED; MOLECULAR DIAGNOSIS; OBSERVATIONAL STUDY; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; RANDOM FOREST; RETROSPECTIVE STUDY; SCHOOL CHILD; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR CLASSIFICATION; TUMOR DIAGNOSIS; TUMOR LOCALIZATION; WHOLE GENOME SEQUENCING; YOUNG ADULT; GENETICS; NANOPORE; PATHOLOGY; PROCEDURES;

BRAIN NEOPLASMS; DNA COPY NUMBER VARIATIONS; DNA METHYLATION; EPIGENOMICS; GENOMICS; GLIOMA; HUMANS; NANOPORES; PROMOTER REGIONS, GENETIC;

EID: 85021149587     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-017-1743-5     Document Type: Article

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