Selective photocytotoxicity of anthrols on cancer stem-like cells: The effect of quinone methides or reactive oxygen species

European Journal of Medicinal Chemistry

Volumn 137, Issue , 2017, Pages 558-574

  Uzelac, Lidija ^a   Škalamera, Đani ^a   Mlinarić Majerski, Kata ^a   Basarić, Nikola ^a   Kralj, Marijeta ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

Antiproliferative activity; Cancer stem cells; Photodehydration; Quinone methides; Reactive oxygen species; Singlet oxygen

Indexed keywords

1,2 ANTHRAQUINONE; 3 (ACETOXYMETHYL) 2 ACETOXYANTRACENE; 3 AZIDOMETHYL 2 HYDROXYANTHACENE; 3 HYDROXMETHYL 2 HYDROXYANTHRACENE; 3 HYDROXYMETHYL 1,2 ANTHRAQUINONE; 3 HYDROXYMETHYL 2 METHOXYANTHRACENE; 3 METHOXYANTHRACENE 2 CARBALDEHYDE; 3 METHOXYMETHYL 2 HYDOXYANTHRACENE; ANTHRACENE DERIVATIVE; ANTHRAQUINONE 2 CARBOXYLIC ACID; METHYL N ACETAMIDO [(2 HYDROXYANTHRACEN 3 YL)METHYL]CYSTEINATE; METHYL N ACETAMIDOCYSTEINATE; QUINONE DERIVATIVE; QUINONE METHIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE;

ABSORPTION SPECTROSCOPY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER RESISTANCE; CANCER STEM CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CYCLE M PHASE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIELS ALDER REACTION; DRUG SELECTIVITY; DRUG SYNTHESIS; ENDOPLASMIC RETICULUM; G2 PHASE CELL CYCLE CHECKPOINT; H460 CANCER CELL LINE; HCT 116 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LUNG CANCER CELL LINE; MCF-7 CELL LINE; OXIDATIVE STRESS; PHOTOCHEMISTRY; PHOTOCYTOTOXICITY; PHOTODYNAMIC THERAPY; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; QUANTUM YIELD; RATE CONSTANT; STEADY STATE; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; METABOLISM; PHOTOCHEMOTHERAPY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLEQUINONES; MOLECULAR STRUCTURE; NEOPLASTIC STEM CELLS; PHOTOCHEMOTHERAPY; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 85020917162     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2017.05.063     Document Type: Article

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