Thermal combination therapies for local drug delivery by magnetic resonance-guided high-intensity focused ultrasound

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 24, 2017, Pages E4802-E4811

  Hijnen, Nicole ^a   Kneepkens, Esther ^a   De Smet, Mariska ^a   Langereis, Sander ^b   Heijman, Edwin ^b,c   Grüll, Holger ^a,c  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b PHILIPS RESEARCH LABORATORIES   (Netherlands)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

Ablation; Drug delivery; Focused ultrasound; Hyperthermia; Temperature sensitive liposomes

Indexed keywords

DOXORUBICIN; GADOTERIDOL; LIPOSOME; SODIUM CHLORIDE; ANTINEOPLASTIC ANTIBIOTIC; INDIUM; MACROGOL DERIVATIVE;

ABLATION THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; FEMALE; FLUORESCENCE MICROSCOPY; HIGH INTENSITY FOCUSED ULTRASOUND; LIPOSOMAL DELIVERY; MULTIMODALITY CANCER THERAPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; RAT MODEL; RHABDOMYOSARCOMA; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY-COMPUTED TOMOGRAPHY; TUMOR GROWTH; ANALOGS AND DERIVATIVES; ANIMAL; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEM; METABOLISM; PROCEDURES; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TEMPERATURE; THERMOTHERAPY; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; HIGH-INTENSITY FOCUSED ULTRASOUND ABLATION; HYPERTHERMIA, INDUCED; INDIUM RADIOISOTOPES; LIPOSOMES; MAGNETIC RESONANCE IMAGING; POLYETHYLENE GLYCOLS; RATS; RHABDOMYOSARCOMA; TEMPERATURE; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 85020800444     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1700790114     Document Type: Article

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