메뉴 건너뛰기




Volumn 10, Issue 2, 2009, Pages 333-343

Lyso-thermosensitive liposomal doxorubicin: A novel approach to enhance efficacy of thermal ablation of liver cancer

Author keywords

Hepatocellular carcinoma; Lyso thermosensitive liposomal doxorubicin; Radiofrequency ablation

Indexed keywords

1 STEAROYL 2 HYDROXY SN GLYCERO 3 PHOSPHOCHOLINE; 1,2 DISTEAROYL SN GLYCERO 3 PHOSPHOETHANOLAMINE N METHOXYPOLYETHYLENEGLYCOL 2000; ACETIC ACID; ALCOHOL; ALPHA2B INTERFERON; CISPLATIN; DIPALMITOYLPHOSPHATIDYLCHOLINE; DOXORUBICIN; FLUOROURACIL; LIPOSOME; NOLATREXED; THERMODOX; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; LYSOPHOSPHATIDYLCHOLINE;

EID: 65649146495     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656560802677874     Document Type: Review
Times cited : (170)

References (86)
  • 1
    • 40549105897 scopus 로고    scopus 로고
    • World Health Organization. Available from: [Last accessed 16 May 2008 ]
    • Revised Global Burden of Disease (GBD) 2002; Estimates. World Health Organization. Available from: http://www.who.int/healthinfo/bodgbd2002;revised/ en/index.html [Last accessed 16 May 2008 ]
    • Revised Global Burden of Disease (GBD) 2002; Estimates
  • 2
    • 0023285403 scopus 로고
    • Cirrhosis and the aetiology of hepatocellular carcinoma
    • Johnson PJ, Williams R. Cirrhosis and the aetiology of hepatocellular carcinoma. J Hepatol 1987;4:140-147
    • (1987) J Hepatol , vol.4 , pp. 140-147
    • Johnson, P.J.1    Williams, R.2
  • 3
    • 67649357648 scopus 로고    scopus 로고
    • Liver cancer. 8th edition
    • Pollock RE, Doroshow JH, Khayat D, et al., editors. Hoboken, NJ: John Wiley & Sons
    • Tang ZY, Curley SA. Liver cancer. 8th edition. In: Pollock RE, Doroshow JH, Khayat D, et al., editors. UICC Manual of Clinical Oncology, Hoboken, NJ: John Wiley & Sons, 2004. p. 405-427
    • (2004) UICC Manual of Clinical Oncology , pp. 405-427
    • Tang, Z.Y.1    Curley, S.A.2
  • 4
    • 0021965806 scopus 로고
    • Natural history of hepatocellular carcinoma and prognosis in relation to treatment
    • Okuda K, Ohtsuki T, Obata H, et al. Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Cancer 1985;56:918-928
    • (1985) Cancer , vol.56 , pp. 918-928
    • Okuda, K.1    Ohtsuki, T.2    Obata, H.3
  • 5
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • DOI 10.1016/S0140-6736(03)14964-1
    • Llovet JM, Burroughs A, Bruix J. Hepatocellular carcinoma. Lancet 2003;362:1907-1917 (Pubitemid 37518510)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 6
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • DOI 10.1002/hep.20933
    • Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005;42:1208-1236 (Pubitemid 43112690)
    • (2005) Hepatology , vol.42 , Issue.5 , pp. 1208-1236
    • Bruix, J.1    Sherman, M.2
  • 7
    • 0015854966 scopus 로고
    • Transection of the oesophagus for bleeding oesophageal varices
    • Pugh RN, Murray-Lyon IM, Dawson JL, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973;60:646-649
    • (1973) Br J Surg , vol.60 , pp. 646-649
    • Pugh, R.N.1    Murray-Lyon, I.M.2    Dawson, J.L.3
  • 8
    • 19644381818 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: The need for progress
    • DOI 10.1200/JCO.2005.03.196
    • Thomas MB, Zhu AX. Hepatocellular carcinoma: the need for progress. J Clin Oncol 2005;23:2892-2899 (Pubitemid 46224106)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.13 , pp. 2892-2899
    • Thomas, M.B.1    Zhu, A.X.2
  • 10
    • 44449085884 scopus 로고    scopus 로고
    • Design and endpoints of clinical trials in hepatocellular carcinoma
    • Llovet JM, Di Bisceglie AM, Bruix M, et al. Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst 2008;100:698-711
    • (2008) J Natl Cancer Inst , vol.100 , pp. 698-711
    • Llovet, J.M.1    Di Bisceglie, A.M.2    Bruix, M.3
  • 13
    • 1942486862 scopus 로고    scopus 로고
    • Laparoscopic radiofrequency ablation of hepatic tumors: Prospective clinical evaluation of ablation size comparing two treatment algorithms
    • DOI 10.1007/s00464-003-8911-5
    • Berber E, Herceg NL, Casto KJ, Siperstein AE. Laparoscopic radiofrequency ablation of hepatic tumors: prospective clinical evaluation of ablation size comparing two treatment algorithms. Surg Endosc 2004;18:390-396 (Pubitemid 38524504)
    • (2004) Surgical Endoscopy , vol.18 , Issue.3 , pp. 390-396
    • Berber, E.1    Herceg, N.L.2    Casto, K.J.3    Siperstein, A.E.4
  • 14
    • 28344451050 scopus 로고    scopus 로고
    • Laparoscopic radiofrequency thermal ablation for unusual hepatic tumors: Operative indications and outcomes
    • DOI 10.1007/s00464-005-0236-0
    • Berber E, Ari E, Herceg N, Siperstein A. Laparoscopic radiofrequency thermal ablation for unusual hepatic tumors: operative indications and outcomes. Surg Endosc 2005;19:1613-1617 (Pubitemid 41719530)
    • (2005) Surgical Endoscopy , vol.19 , Issue.12 , pp. 1613-1617
    • Berber, E.1    Ari, E.2    Herceg, N.3    Siperstein, A.4
  • 15
    • 33947316450 scopus 로고    scopus 로고
    • Perioperative outcome after laparoscopic radiofrequency ablation of liver tumors: An analysis of 521 cases
    • DOI 10.1007/s00464-006-9139-y
    • Berber E, Siperstein AE. Perioperative outcome after laparoscopic radiofrequency ablation of liver tumors: an analysis of 521 cases. Surg Endosc 2007;21:613-618 (Pubitemid 46439380)
    • (2007) Surgical Endoscopy , vol.21 , Issue.4 , pp. 613-618
    • Berber, E.1    Siperstein, A.E.2
  • 17
    • 84921622821 scopus 로고    scopus 로고
    • Radiofrequency thermal ablation versus other interventions for hepatocellular carcinoma
    • CD003046
    • Galandi D, Antes G. Radiofrequency thermal ablation versus other interventions for hepatocellular carcinoma. Cochrane Database Syst Rev 2002;3:CD003046
    • (2002) Cochrane Database Syst Rev , vol.3
    • Galandi, D.1    Antes, G.2
  • 19
    • 40949089014 scopus 로고    scopus 로고
    • Radiofrequency ablation of primary and metastatic liver tumors: A critical review of the literature
    • Garrean S, Hering J, Saied A, et al. Radiofrequency ablation of primary and metastatic liver tumors: a critical review of the literature. Am J Surg 2008;195:508-520
    • (2008) Am J Surg , vol.195 , pp. 508-520
    • Garrean, S.1    Hering, J.2    Saied, A.3
  • 20
    • 22644441192 scopus 로고    scopus 로고
    • Randomised controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percutaneous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less
    • DOI 10.1136/gut.2004.045203
    • Lin SM, Lin CJ, Lin CC, et al. Randomized controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percuteanous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less. Gut 2005;54:1151-1156 (Pubitemid 41025911)
    • (2005) Gut , vol.54 , Issue.8 , pp. 1151-1156
    • Lin, S.-M.1    Lin, C.-J.2    Lin, C.-C.3    Hsu, C.-W.4    Chen, Y.-C.5
  • 23
    • 9644265250 scopus 로고    scopus 로고
    • Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma <4 cm
    • DOI 10.1053/j.gastro.2004.09.003, PII S0016508504015720
    • Lin SM, Lin CJ, Lin CC, et al. Radiofrequency ablation improves prognosis compared with ethanol injection for hepatocellular carcinoma < or = 4 cm. Gastroenterology 2004;127:1714-1723 (Pubitemid 39575850)
    • (2004) Gastroenterology , vol.127 , Issue.6 , pp. 1714-1723
    • Lin, S.-M.1    Lin, C.-J.2    Lin, C.-C.3    Hsu, C.-W.4    Chen, Y.-C.5
  • 24
    • 33644662778 scopus 로고    scopus 로고
    • A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma
    • DOI 10.1097/01.sla.0000201480.65519.b8
    • Chen MS, Li JQ, Zheng Y, et al. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg 2006;243:321-8 • Randomized trial showing that, for small/medium hepatocellular carcinoma, percutaneous radiofrequency ablation and surgical resection are not significantly different in overall survival; it also shows that percutaneous radiofrequency ablation is both less toxic and less costly than surgery. (Pubitemid 43327762)
    • (2006) Annals of Surgery , vol.243 , Issue.3 , pp. 321-328
    • Chen, M.-S.1    Li, J.-Q.2    Zheng, Y.3    Guo, R.-P.4    Liang, H.-H.5    Zhang, Y.-Q.6    Lin, X.-J.7    Lau, W.Y.8
  • 26
    • 7444229833 scopus 로고    scopus 로고
    • Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome
    • Chen Q, Tong S, Dewhirst MW, Yuan F. Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome. Mol Cancer Ther 2004;3:1311-1317 (Pubitemid 39440175)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.10 , pp. 1311-1317
    • Chen, Q.1    Tong, S.2    Dewhirst, M.W.3    Yuan, F.4
  • 27
    • 0034834762 scopus 로고    scopus 로고
    • Radiofrequency thermal ablation: Computer analysis of the size of the thermal injury created by overlapping ablations
    • Dodd GD 3rd, Frank Ms, Aribandi M, et al. Radiofrequency thermal ablation: computer analysis of the size of the thermal injury created by overlapping ablations. Am J Roentgenol 2001;177:777-782
    • (2001) Am J Roentgenol , vol.177 , pp. 777-782
    • Dodd III, G.D.1    Frank, Ms.2    Aribandi, M.3
  • 30
    • 20044386501 scopus 로고    scopus 로고
    • Percutaneous radiofrequency ablation for hepatocellular carcinoma. An analysis of 1000 cases
    • Tateishi R, Shiina S, Teratani T, et al. Percutaneous radiofrequency ablation for hepatocellular carcinoma. An analysis of 1000 cases. Cancer 2005;103:1201-1209
    • (2005) Cancer , vol.103 , pp. 1201-1209
    • Tateishi, R.1    Shiina, S.2    Teratani, T.3
  • 31
    • 1442336120 scopus 로고    scopus 로고
    • Effectiveness of Radiofrequency Ablation for Hepatocellular Carcinomas Larger Than 3 cm in Diameter
    • DOI 10.1001/archsurg.139.3.281
    • Poon RT, Ng KK, Lam CM, et al. Effectiveness of radiofrequency ablation for hepatocellular carcinomas larger than 3 cm in diameter. Arch Surg 2004;139:281-287 (Pubitemid 38282669)
    • (2004) Archives of Surgery , vol.139 , Issue.3 , pp. 281-287
    • Poon, R.T.-P.1    Ng, K.K.C.2    Lam, C.-M.3    Ai, V.4    Yuen, J.5    Fan, S.-T.6
  • 32
    • 3042658706 scopus 로고    scopus 로고
    • Surgical resection versus percutaneous radiofrequency ablation in the treatment of hepatocellular carcinoma on cirrhotic liver
    • DOI 10.1097/01.sla.0000129672.51886.44
    • Vivarelli M, Guglielmi A, Ruzzenente A, et al. Surgical resection versus percutaneous radiofrequency ablation in the treatment of hepatocellular carcinoma on cirrhotic liver. Ann Surg 2004;240:102-107 (Pubitemid 38808241)
    • (2004) Annals of Surgery , vol.240 , Issue.1 , pp. 102-107
    • Vivarelli, M.1    Guglielmi, A.2    Ruzzenente, A.3    Cucchetti, A.4    Bellusci, R.5    Cordiano, C.6    Cavallari, A.7
  • 33
    • 28244493625 scopus 로고    scopus 로고
    • Long-term follow-up outcome of patients undergoing radiofrequency ablation for unresectable hepatocellular carcinoma
    • DOI 10.1007/s00268-005-7829-6
    • Machi J, Bueno RS, Wong LL. Long-term follow-up outcome of patients undergoing radiofrequency ablation for unresectable hepatocellular carcinoma. World J Surg 2005;29:1364-1373 (Pubitemid 41712667)
    • (2005) World Journal of Surgery , vol.29 , Issue.11 , pp. 1364-1373
    • Machi, J.1    Bueno, R.S.2    Wong, L.L.3
  • 34
    • 38149091762 scopus 로고    scopus 로고
    • Analysis of recurrence pattern and its influence on survival outcome after radiofrequency ablation of hepatocellular carcinoma
    • Ng KK, Poon RT, Lo CM, et al. Analysis of recurrence pattern and its influence on survival outcome after radiofrequency ablation of hepatocellular carcinoma. J Gastrointest Surg 2008;12:183-191
    • (2008) J Gastrointest Surg , vol.12 , pp. 183-191
    • Ng, K.K.1    Poon, R.T.2    Lo, C.M.3
  • 35
    • 22744441092 scopus 로고    scopus 로고
    • Local recurrence after hepatic radiofrequency coagulation: Multivariate meta-analysis and review of contributing factors
    • DOI 10.1097/01.sla.0000171032.99149.fe
    • Mulier S, Ni Y, Jamart J, et al. Local recurrence after hepatic radiofrequency coagulation: multivariate meta-analysis and review of contributing factors. Ann Surg 2005;242:158-171 (Pubitemid 41033431)
    • (2005) Annals of Surgery , vol.242 , Issue.2 , pp. 158-171
    • Mulier, S.1    Ni, Y.2    Jamart, J.3    Ruers, T.4    Marchal, G.5    Michel, L.6
  • 36
    • 33745802069 scopus 로고    scopus 로고
    • Randomized clinical trial of percutaneous radiofrequency ablation plus absolute ethanol injection compared with radiofrequency ablation alone for small hepatocellular carcinoma
    • Randomized trial showing that, for medium HCC, RFA alone is significantly less effective than RFA plus PEI
    • Chen MS, Zhang YJ, Li JQ, et al. Randomized clinical trial of percutaneous radiofrequency ablation plus absolute ethanol injection compared with radiofrequency ablation alone for small hepatocellular carcinoma. Zhonghua Zhong Liu Za Zhi 2005;27:623-5 • Randomized trial showing that, for medium HCC, RFA alone is significantly less effective than RFA plus PEI.
    • (2005) Zhonghua Zhong Liu Za Zhi , vol.27 , pp. 623-625
    • Chen, M.S.1    Zhang, Y.J.2    Li, J.Q.3
  • 37
    • 34447514076 scopus 로고    scopus 로고
    • Hepatocellular carcinoma treated with radiofrequency ablation with or without ethanol injection: A prospective randomized trial
    • Randomized trial showing that RFA plus PEI is significantly more effective than RFA alone for medium HCC but not for either small HCC or large HCC
    • Zhang YJ, Liang HH, Chen MS, et al. Hepatocellular carcinoma treated with radiofrequency ablation with or without ethanol injection: a prospective randomized trial. Radiology 2007;244:599-607 • Randomized trial showing that RFA plus PEI is significantly more effective than RFA alone for medium HCC but not for either small HCC or large HCC.
    • (2007) Radiology , vol.244 , pp. 599-607
    • Zhang, Y.J.1    Liang, H.H.2    Chen, M.S.3
  • 38
    • 67649309179 scopus 로고    scopus 로고
    • Doxorubicin Product Information, Bedford, OH, USA. Available from: [Last accessed 23 May 2008 ]
    • Doxorubicin Product Information, Bedford Laboratories, Bedford, OH, USA. Available from: http://www.bedfordlabs.com/products/inserts/ADR-P01.pdf [Last accessed 23 May 2008 ]
  • 39
    • 67649370014 scopus 로고    scopus 로고
    • Pfizer Canada Inc., Kirkland, Quebec, Canada, Available from: [Last accessed 16 June 2008 ]
    • Product Monograph- Adriamycin: doxorubicin hydrochloride injection. Pfizer Canada Inc., Kirkland, Quebec, Canada, 2007. Available from: http://www.pfizer.ca/english/our%20products/prescription%20pharmaceuticals/ default.asp?s=1&id=35&doc=enmonograph [Last accessed 16 June 2008 ]
    • (2007) Product Monograph- Adriamycin: Doxorubicin Hydrochloride Injection
  • 40
    • 0023936352 scopus 로고
    • Clinical trials in primary hepatocellular carcinoma: Current status and future directions
    • Nerenstone SR, Inde DC, Friedman MA. Clinical trials in primary hepatocellular carcinoma: current status and future directions. Cancer Treat Rev 1988;15:1-31 (Pubitemid 18137783)
    • (1988) Cancer Treatment Reviews , vol.15 , Issue.1 , pp. 1-31
    • Nerenstone, S.R.1    Ihde, D.C.2    Friedman, M.A.3
  • 41
    • 0023765990 scopus 로고
    • Doxorubicin vs. no antitumor therapy in an inoperable hepatocellular carcinoma: A prospective randomized trial
    • Randomized trial showing that single-agent doxorubicin is superior to no anticancer treatment for HCC
    • Lai CL, Wu PC, Chan GC, et al. Doxorubicin vs. no antitumor therapy in an inoperable hepatocellular carcinoma: a prospective randomized trial. Cancer 1988;62:479-83 • Randomized trial showing that single-agent doxorubicin is superior to no anticancer treatment for HCC.
    • (1988) Cancer , vol.62 , pp. 479-483
    • Lai, C.L.1    Wu, P.C.2    Chan, G.C.3
  • 44
    • 0021749698 scopus 로고
    • Intraarterial adriamycin for patients with hepatocellular carcinoma and metastatic liver carcinoma
    • Ueoka H, Kuroda S, Ohnoshi T, et al. Intraarterial Adriamycin for patients with hepatocellular carcinoma and metastatic liver carcinoma. Gan To Kagaku Ryoho 1984;11:2579-2584 (Pubitemid 15192078)
    • (1984) Japanese Journal of Cancer and Chemotherapy , vol.11 , Issue.12 , pp. 2579-2584
    • Ueoka, H.1    Kuroda, S.2    Ohnoshi, T.3
  • 46
    • 0025201787 scopus 로고
    • Intraarterial adriamycin and lipiodol for inoperable hepatocellular carcinoma: A comparison with intravenous adriamycin
    • Kalayci C, Johnson PJ, Raby N, et al. Intraarterial adriamycin and lipiodol for inoperable hepatocellular carcinoma: a comparison with intravenous adriamycin. J Hepatol 1990;11:349-353
    • (1990) J Hepatol , vol.11 , pp. 349-353
    • Kalayci, C.1    Johnson, P.J.2    Raby, N.3
  • 48
    • 85132526751 scopus 로고    scopus 로고
    • Nanoscale drug delivery vehicles for solid tumors: A new paradigm for localized drug delivery using temperature sensitive liposomes
    • Amiji M, editor. Boca Raton, FL: CRC Press
    • Needham D, Ponce A. Nanoscale drug delivery vehicles for solid tumors: a new paradigm for localized drug delivery using temperature sensitive liposomes. In: Amiji M, editor. Nanotechnology in Cancer Therapy. Boca Raton, FL: CRC Press; 2006. p. 677-719
    • (2006) Nanotechnology in Cancer Therapy , pp. 677-719
    • Needham, D.1    Ponce, A.2
  • 51
    • 8644276416 scopus 로고    scopus 로고
    • Combination radiofrequency thermal ablation and adjuvant IV liposomal doxorubicin increases tissue coagulation and intratumoural drug accumulation
    • DOI 10.1080/02656730410001711655
    • Ahmed M, Goldberg SN. Combination radiofrequency thermal ablation and adjuvant iv liposomal doxorubicin increases tissue coagulation and intratumoral drug accumulation. Int J Hyperthermia 2004;20:781-802 (Pubitemid 39496856)
    • (2004) International Journal of Hyperthermia , vol.20 , Issue.7 , pp. 781-802
    • Ahmed, M.1    Goldberg, S.N.2
  • 53
    • 17644372748 scopus 로고    scopus 로고
    • Combination radiofrequency ablation with intratumoral liposomal doxorubicin: Effect on drug accumulation and coagulation in multiple tissues and tumor types in animals
    • DOI 10.1148/radiol.2352031856
    • Ahmed M, Liu Z, Lukyanov AN, et al. Combination radiofrequency ablation with intratumoral liposomal doxorubicin: effect on drug accumulation and coagulation in multiple tissues and tumor types in animals. Radiology 2005;235:469-477 (Pubitemid 40571084)
    • (2005) Radiology , vol.235 , Issue.2 , pp. 469-477
    • Ahmed, M.1    Liu, Z.2    Lukyanov, A.N.3    Signoretti, S.4    Horkan, C.5    Monsky, W.L.6    Torchilin, V.P.7    Goldberg, S.N.8
  • 54
    • 0034212346 scopus 로고    scopus 로고
    • Treatment of intrahepatic malignancy with radiofrequency ablation: Radiologic-pathologic correlation
    • DOI 10.1002/1097-0142(20000601)88:11<2452::AID-CNCR5>3.0.CO;2-3
    • Goldberg SN, Gazelle GS, Compton CC, et al. Treatment of intrahepatic malignancy with radiofrequency ablation: radiologic-pathologic correlation. Cancer 2000;88:2452-2463 (Pubitemid 30331950)
    • (2000) Cancer , vol.88 , Issue.11 , pp. 2452-2463
    • Goldberg, S.N.1    Gazelle, G.S.2    Compton, C.C.3    Mueller, P.R.4    Tanabe, K.K.5
  • 56
    • 11144226974 scopus 로고    scopus 로고
    • Liposomal doxorubicin combined with regional hyperthermia: Reducing systemic toxicity and improving locoregional efficacy in the treatment of solid tumors
    • Dvorak J, Zoul Z, Melichar B, et al. Liposomal doxorubicin combined with regional hyperthermia: reducing systemic toxicity and improving locoregional efficacy in the treatment of solid tumors. J Chemother 2004;16(Suppl 5):34-36 (Pubitemid 40052986)
    • (2004) Journal of Chemotherapy , vol.16 , Issue.SUPPL. 5 , pp. 34-36
    • Dvorak, J.1    Zoul, Z.2    Melichar, B.3    Petera, J.4    Vesely, P.5    Vosmik, M.6    Dolezel, M.7
  • 57
    • 34047182107 scopus 로고    scopus 로고
    • Enhanced efficacy of anti-tumor liposomal doxorubicin by hyperthermia
    • Liu P, Xu LX, Zhang A. Enhanced efficacy of anti-tumor liposomal doxorubicin by hyperthermia. Conf Proc IEEE Eng Med Biol Soc 2006;1:4354-4357
    • (2006) Conf Proc IEEE Eng Med Biol Soc , vol.1 , pp. 4354-4357
    • Liu, P.1    Xu, L.X.2    Zhang, A.3
  • 60
    • 0020054278 scopus 로고
    • Effect of heating on lethality due to hyperthermia and selected chemotherapeutic drugs
    • Herman TS, Sweets CC, White DM, Gerner EW. Effect of heating on lethality due to hyperthermia and selected chemotherapeutic drugs. J Natl Cancer Inst 1982;68:487-491
    • (1982) J Natl Cancer Inst , vol.68 , pp. 487-491
    • Herman, T.S.1    Sweets, C.C.2    White, D.M.3    Gerner, E.W.4
  • 61
    • 0020664020 scopus 로고
    • Temperature dependence of Adriamycin, cis-diamminedichloroplatinum, bleomycin, and 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in vitro
    • Herman TS. Temperature dependence of adriamycin, cis- diamminedichloroplatinum, bleomycin, and 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in vitro. Cancer Res 1983;43:517-520 (Pubitemid 13193840)
    • (1983) Cancer Research , vol.43 , Issue.2 , pp. 517-520
    • Herman, T.S.1
  • 62
    • 0023002370 scopus 로고
    • Hyperthermia, Adriamycin transport, and cytotoxicity in drug-sensitive and -resistant Chinese hamster ovary cells
    • Bates DA, Mackillop WJ. Hyperthermia, adriamycin transport, and cytotoxicity in drug-sensitive and-resistant Chinese hamster ovary cells. Cancer Res 1986;46:5477-5481 (Pubitemid 17177930)
    • (1986) Cancer Research , vol.46 , Issue.11 , pp. 5477-5481
    • Bates, D.A.1    Mackillop, W.J.2
  • 63
    • 0022642964 scopus 로고
    • Intracellular uptake, retention and cytotoxic effect of adriamycin combined with hyperthermia in vitro
    • Nagaoka S, Kawasaki S, Sasaki K, Nakanishi T. Intracellular uptake, retention and cytotoxic effect of adriamycin combined with hyperthermia in vitro. Jpn J Cancer Res 1986;77:205-211 (Pubitemid 16138117)
    • (1986) Japanese Journal of Cancer Research , vol.77 , Issue.2 , pp. 205-211
    • Nagaoka, S.1    Kawasaki, S.2    Sasaki, K.3    Nakanishi, T.4
  • 64
    • 0023796408 scopus 로고
    • Combined cell killing effects of anticancer drugs and hyperthermia in vitro
    • Nitta M, Hisazumi H, Nakajima K. Combined cell killing effects of anticancer drugs and hyperthermia in vitro. Hinyokika Kiyo 1988;34:1525-1528 (Pubitemid 18242645)
    • (1988) Acta Urologica Japonica , vol.34 , Issue.9 , pp. 1525-1528
    • Nitta, M.1    Hisazumi, H.2    Nakajima, K.3
  • 65
    • 0024512586 scopus 로고
    • In vitro thermo-chemosensitivity screening of spontaneous human tumors: Significant potentiation for cisplatin but not adriamycin
    • Calabro A, Singletary SE, Tucker S, et al. In vitro thermo- chemosensitivity screening of spontaneous human tumors: significant potentiation for cisplatin but not adriamycin. Int J Cancer 1989;43:385-390
    • (1989) Int J Cancer , vol.43 , pp. 385-390
    • Calabro, A.1    Singletary, S.E.2    Tucker, S.3
  • 66
    • 0026431659 scopus 로고
    • Effect of adriamycin combined with 40 and 43 degrees C hyperthermia on cultured V79 cells and S-180 tumor and their uptake of the drug
    • Yoshida M. Effect of adriamycin combined with 40 and 43 degrees C hyperthermia on cultured V79 cells and S-180 tumor and their uptake of the drug. Nippon Igaku Hoshasen Gakkai Zasshi 1991;51:1098-1104
    • (1991) Nippon Igaku Hoshasen Gakkai Zasshi , vol.51 , pp. 1098-1104
    • Yoshida, M.1
  • 67
    • 0027768139 scopus 로고
    • Studies of combined treatment of radiofrequency hyperthermia with anticancer agents or irradiation for invasive bladder cancer
    • Uchibayashi T, Lee SW, Hisazumi H, et al. Studies of combined treatment of radiofrequency hyperthermia with anticancer agents or irradiation for invasive bladder cancer. Hinyokika Kiyo 1993;39:1209-1213
    • (1993) Hinyokika Kiyo , vol.39 , pp. 1209-1213
    • Uchibayashi, T.1    Lee, S.W.2    Hisazumi, H.3
  • 68
    • 0028569304 scopus 로고
    • Studies of effects of anticancer agents in combinatian with/without hyperthermia on metastasized human bladder cancer cells in chick embryos using the polymerase chain reaction technique
    • DOI 10.1007/BF00686927
    • Uchibayashi T, Lee SW, Kunimi K, et al. Studies of effects of anticancer agents in combination with/without hyperthermia on metastasized human bladder cancer cells in chick embryos using the polymerase chain reaction technique. Cancer Chemother Pharmacol 1994;35(Suppl): S84-7 (Pubitemid 24357249)
    • (1994) Cancer Chemotherapy and Pharmacology , vol.35 , Issue.SUPPL.
    • Uchibayashi, T.1    Lee, S.-W.2    Kunimi, K.3    Ohkawa, M.4    Endo, Y.5    Noguchi, M.6    Sasaki, T.7
  • 69
    • 0028102971 scopus 로고
    • Interaction between adriamycin cytotoxicity and hyperthermia: Growth-phase-dependent thermal sensitization
    • Urano M, Begley J, Reynolds R. Interaction between adriamycin cytotoxicity and hyperthermia: growth-phase-dependent thermal sensitization. Int J Hyperthermia 1994;10:817-826 (Pubitemid 24352989)
    • (1994) International Journal of Hyperthermia , vol.10 , Issue.6 , pp. 817-826
    • Urano, M.1    Begley, J.2    Reynolds, R.3
  • 70
    • 0035490820 scopus 로고    scopus 로고
    • Modification of thermosensitivity and chemosensitivity induced by combined treatments with hyperthermia and adriamycin
    • Hayashi S, Kano E, Tsuji K, et al. Modification of thermosensitivity and chemosensitivity induced by combined treatments with hyperthermia and adriamycin. Int J Mol Med 2001;8:417-422
    • (2001) Int J Mol Med , vol.8 , pp. 417-422
    • Hayashi, S.1    Kano, E.2    Tsuji, K.3
  • 71
    • 42049089936 scopus 로고    scopus 로고
    • Dose enhancement effect of anticancer drugs associated with increased temperature in vitro
    • Istomin YP, Zhavrid EA, Alexandrova EN, et al. Dose enhancement effect of anticancer drugs associated with increased temperature in vitro. Exp Oncol 2008;30:56-59
    • (2008) Exp Oncol , vol.30 , pp. 56-59
    • Istomin, Y.P.1    Zhavrid, E.A.2    Alexandrova, E.N.3
  • 75
    • 0036775308 scopus 로고    scopus 로고
    • Radiofrequency ablation of liver tumors: Influence of technique and tumor size
    • DOI 10.1067/msy.2002.127545
    • Kuvshinoff BW, Ota DM. Radiofrequency ablation of liver tumors: influence of technique and tumor size. Surgery 2002;132:605-611 (Pubitemid 35247322)
    • (2002) Surgery , vol.132 , Issue.4 , pp. 605-612
    • Kuvshinoff, B.W.1    Ota, D.M.2
  • 76
    • 0002218707 scopus 로고
    • Liver and bile ducts
    • Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE, editors. New York: Churchill Livingstone
    • Curley SA, Levin B, Rich TA. Liver and bile ducts. In: Abeloff MD, Armitage JO, Lichter AS, Niederhuber JE, editors. Clinical Oncology. New York: Churchill Livingstone, 1995
    • (1995) Clinical Oncology
    • Curley, S.A.1    Levin, B.2    Rich, T.A.3
  • 77
    • 0022545976 scopus 로고
    • Cytotoxic effects of hyperthermia, 5-fluorouracil and their combination on a human leukemia T-lymphoblast cell line, CCRF-CEM
    • DOI 10.1016/0277-5379(86)90058-1
    • Mini E, Dombrowski J, Moroson BA, Bertino JR. Cytotoxic effects of hyperthermia, 5-fluorouracil and their combination on a human leukemia T-lymphoblast cell line, CCRF-CEM. Eur J Cancer Clin Oncol 1986;22:927-934 (Pubitemid 16035143)
    • (1986) European Journal of Cancer and Clinical Oncology , vol.22 , Issue.8 , pp. 927-934
    • Mini, E.1    Dombrowski, J.2    Moroson, B.A.3    Bertino, J.R.4
  • 78
    • 0026236179 scopus 로고
    • Comparative antitumor activity of 5-fluorouracil and its prodrugs in combination with hyperthermia in vitro
    • Shiiki S, Fuchimoto S, Iwagaki H, et al. Comparative antitumor activity of 5-fluorouracil and its prodrugs in combination with hyperthermia in vitro. Acta Med Okayama 1991;45:339-345
    • (1991) Acta Med Okayama , vol.45 , pp. 339-345
    • Shiiki, S.1    Fuchimoto, S.2    Iwagaki, H.3
  • 79
    • 0026601225 scopus 로고
    • 5-Fluorouracil's cytotoxicity is enhanced both in vitro and in vivo by concomitant treatment with hyperthermia and dipyridamole
    • Maehara Y, Sakaguchi Y, Takahashi I, et al. 5-Fluorouracil's cytotoxicity is enhanced both in vitro and in vivo by concomitant treatment with hyperthermia and dipyridamole. Cancer Chemother Pharmacol 1992;29:257-260
    • (1992) Cancer Chemother Pharmacol , vol.29 , pp. 257-260
    • Maehara, Y.1    Sakaguchi, Y.2    Takahashi, I.3
  • 80
    • 0037680639 scopus 로고    scopus 로고
    • A phase II and pharmacokinetic study of pegylated liposomal doxorubicin in patients with advanced hepatocellular carcinoma
    • Hong RL, Tseng YL. A Phase II and pharmacokinetic study of pegylated liposomal doxorubicin in patients with advanced hepatocellular carcinoma. Cancer Chemother Pharmacol 2003;51:433-438 (Pubitemid 36649142)
    • (2003) Cancer Chemotherapy and Pharmacology , vol.51 , Issue.5 , pp. 433-438
    • Hong, R.-L.1    Tseng, Y.-L.2
  • 81
    • 33847029662 scopus 로고    scopus 로고
    • Efficacy of pegylated liposomal doxorubicin in patients with advanced hepatocellular carcinoma
    • DOI 10.1080/02841860600693473, PII 770503936
    • Lind PA, Naucler G, Holm A, et al. Efficacy of pegylated liposomal doxorubicin in patients with advanced hepatocellular carcinoma. Acta Oncol 2007;46:230-233 (Pubitemid 46272613)
    • (2007) Acta Oncologica , vol.46 , Issue.2 , pp. 230-233
    • Lind, P.A.1    Naucler, G.2    Holm, A.3    Gubanski, M.4    Svensson, C.5
  • 84
    • 67649316780 scopus 로고    scopus 로고
    • International Clinical Trials Registry. Available from: [Last accessed 4 June 2008 ] Will provide definitive test of RFA/LTLD therapy for medium/large HCC
    • International Clinical Trials Registry. World Health Organization. Available from: http://www.who.int/trialsearch/advsearch.aspx; Study ID# NCT00617981 [Last accessed 4 June 2008 ] •• Will provide definitive test of RFA/LTLD therapy for medium/large HCC.
  • 85
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Statist Ass 1958;53:457-481
    • (1958) J Am Statist Ass , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 86
    • 0017365573 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observation of each patient
    • Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Br J Cancer 1977;35:1-39
    • (1977) Br J Cancer , vol.35 , pp. 1-39
    • Peto, R.1    Pike, M.C.2    Armitage, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.