Targeted drug delivery by high intensity focused ultrasound mediated hyperthermia combined with temperature-sensitive liposomes: Computational modelling and preliminary in vivovalidation

International Journal of Hyperthermia

Volumn 28, Issue 4, 2012, Pages 337-348

  Gasselhuber, Astrid ^a   Dreher, Matthew R ^b   Partanen, Ari ^b,c,d   Yarmolenko, Pavel S ^b,e   Woods, David ^b   Wood, Bradford J ^b   Haemmerich, Dieter ^a,f  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

^d PHILIPS HEALTHCARE   (United States)

^e USA   (United States)

^f South   (United States)

Author keywords

Drug delivery; Focused ultrasound; Hyperthermia; Liposome; MR HIFU; TSL

Indexed keywords

DOXORUBICIN; LIPOSOME; TEMPERATURE SENSITIVE LIPOSOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL SURVIVAL; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TRANSPORT; DRUG UPTAKE; FLUORESCENCE; HEAT TRANSFER; HEATING; HIGH INTENSITY FOCUSED ULTRASOUND; HYPERTHERMIA MEDIATED DRUG DELIVERY SYSTEM; IN VIVO STUDY; MATHEMATICAL MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION; RABBIT; TEMPERATURE SENSITIVITY; VALIDATION STUDY;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; COMPUTER SIMULATION; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HIGH-INTENSITY FOCUSED ULTRASOUND ABLATION; HYPERTHERMIA, INDUCED; LIPOSOMES; NEOPLASMS; RABBITS; TEMPERATURE;

EID: 84861524634     PISSN: 02656736     EISSN: 14645157     Source Type: Journal    
DOI: 10.3109/02656736.2012.677930     Document Type: Article

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