-
1
-
-
84958777155
-
Clinical application: restoration of immune homeostasis by autophagy as a potential therapeutic target in sepsis
-
Zhang, L., Ai, Y., Tsung, A., Clinical application: restoration of immune homeostasis by autophagy as a potential therapeutic target in sepsis. Exp. Ther. Med. 11 (2016), 1159–1167.
-
(2016)
Exp. Ther. Med.
, vol.11
, pp. 1159-1167
-
-
Zhang, L.1
Ai, Y.2
Tsung, A.3
-
2
-
-
84871387550
-
Human macrophage and dendritic cell-specific silencing of high-mobility group protein B1 ameliorates sepsis in a humanized mouse model
-
Ye, C., Choi, J.G., Abraham, S., Wu, H., Diaz, D., Terreros, D., Shankar, P., Manjunath, N., Human macrophage and dendritic cell-specific silencing of high-mobility group protein B1 ameliorates sepsis in a humanized mouse model. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 21052–21057.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 21052-21057
-
-
Ye, C.1
Choi, J.G.2
Abraham, S.3
Wu, H.4
Diaz, D.5
Terreros, D.6
Shankar, P.7
Manjunath, N.8
-
3
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss, R.S., Karl, I.E., The pathophysiology and treatment of sepsis. N. Engl. J. Med. 348 (2003), 138–150.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
4
-
-
84858698598
-
Sepsis immunopathology: perspectives of monitoring and modulation of the immune disturbances
-
Skirecki, T., Borkowska-Zielinska, U., Zlotorowicz, M., Hoser, G., Sepsis immunopathology: perspectives of monitoring and modulation of the immune disturbances. Arch. Immunol. Ther. Exp. (Warsz) 60 (2012), 123–135.
-
(2012)
Arch. Immunol. Ther. Exp. (Warsz)
, vol.60
, pp. 123-135
-
-
Skirecki, T.1
Borkowska-Zielinska, U.2
Zlotorowicz, M.3
Hoser, G.4
-
5
-
-
0032770246
-
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
-
Hotchkiss, R.S., Swanson, P.E., Freeman, B.D., Tinsley, K.W., Cobb, J.P., Matuschak, G.M., Buchman, T.G., Karl, I.E., Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit. Care Med. 27 (1999), 1230–1251.
-
(1999)
Crit. Care Med.
, vol.27
, pp. 1230-1251
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Freeman, B.D.3
Tinsley, K.W.4
Cobb, J.P.5
Matuschak, G.M.6
Buchman, T.G.7
Karl, I.E.8
-
6
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
Hotchkiss, R.S., Nicholson, D.W., Apoptosis and caspases regulate death and inflammation in sepsis. Nat. Rev. Immunol. 6 (2006), 813–822.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
7
-
-
0031809765
-
Proinflammatory mediator activity, endogenous antagonists and the systemic inflammatory response in intra-abdominal sepsis. Scottish sepsis intervention group
-
Wakefield, C.H., Barclay, G.R., Fearon, K.C., Goldie, A.S., Ross, J.A., Grant, I.S., Ramsay, G., Howie, J.C., Proinflammatory mediator activity, endogenous antagonists and the systemic inflammatory response in intra-abdominal sepsis. Scottish sepsis intervention group. Br. J. Surg. 85 (1998), 818–825.
-
(1998)
Br. J. Surg.
, vol.85
, pp. 818-825
-
-
Wakefield, C.H.1
Barclay, G.R.2
Fearon, K.C.3
Goldie, A.S.4
Ross, J.A.5
Grant, I.S.6
Ramsay, G.7
Howie, J.C.8
-
8
-
-
0029903114
-
Sir isaac newton, sepsis, SIRS, and CARS
-
Bone, R.C., Sir isaac newton, sepsis, SIRS, and CARS. Crit. Care Med. 24 (1996), 1125–1128.
-
(1996)
Crit. Care Med.
, vol.24
, pp. 1125-1128
-
-
Bone, R.C.1
-
9
-
-
84860660690
-
Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis
-
Zhu, J., Wang, J., Sheng, Y., Zou, Y., Bo, L., Wang, F., Lou, J., Fan, X., Bao, R., Wu, Y., Chen, F., Deng, X., Li, J., Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis. PLoS One, 7, 2012, e35523.
-
(2012)
PLoS One
, vol.7
, pp. e35523
-
-
Zhu, J.1
Wang, J.2
Sheng, Y.3
Zou, Y.4
Bo, L.5
Wang, F.6
Lou, J.7
Fan, X.8
Bao, R.9
Wu, Y.10
Chen, F.11
Deng, X.12
Li, J.13
-
10
-
-
0026016470
-
Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group
-
Ziegler, E.J., Fisher, C.J. Jr., Sprung, C.L., Straube, R.C., Sadoff, J.C., Foulke, G.E., Wortel, C.H., Fink, M.P., Dellinger, R.P., Teng, N.N., et al. Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group. N. Engl. J. Med. 324 (1991), 429–436.
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 429-436
-
-
Ziegler, E.J.1
Fisher, C.J.2
Sprung, C.L.3
Straube, R.C.4
Sadoff, J.C.5
Foulke, G.E.6
Wortel, C.H.7
Fink, M.P.8
Dellinger, R.P.9
Teng, N.N.10
-
11
-
-
0028018567
-
Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial
-
Fisher, C.J. Jr., Slotman, G.J., Opal, S.M., Pribble, J.P., Bone, R.C., Emmanuel, G., Ng, D., Bloedow, D.C., Catalano, M.A., Group, I.-R.S.S.S., Initial evaluation of human recombinant interleukin-1 receptor antagonist in the treatment of sepsis syndrome: a randomized, open-label, placebo-controlled multicenter trial. Crit. Care Med. 22 (1994), 12–21.
-
(1994)
Crit. Care Med.
, vol.22
, pp. 12-21
-
-
Fisher, C.J.1
Slotman, G.J.2
Opal, S.M.3
Pribble, J.P.4
Bone, R.C.5
Emmanuel, G.6
Ng, D.7
Bloedow, D.C.8
Catalano, M.A.9
Group, I.-R.S.S.S.10
-
12
-
-
0029900294
-
Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The soluble TNF receptor sepsis study group
-
Fisher, C.J. Jr., Agosti, J.M., Opal, S.M., Lowry, S.F., Balk, R.A., Sadoff, J.C., Abraham, E., Schein, R.M., Benjamin, E., Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The soluble TNF receptor sepsis study group. N. Engl. J. Med. 334 (1996), 1697–1702.
-
(1996)
N. Engl. J. Med.
, vol.334
, pp. 1697-1702
-
-
Fisher, C.J.1
Agosti, J.M.2
Opal, S.M.3
Lowry, S.F.4
Balk, R.A.5
Sadoff, J.C.6
Abraham, E.7
Schein, R.M.8
Benjamin, E.9
-
13
-
-
59649117667
-
Molecular biology of inflammation and sepsis: a primer
-
Cinel, I., Opal, S.M., Molecular biology of inflammation and sepsis: a primer. Crit. Care Med. 37 (2009), 291–304.
-
(2009)
Crit. Care Med.
, vol.37
, pp. 291-304
-
-
Cinel, I.1
Opal, S.M.2
-
14
-
-
84891645973
-
The changing immune system in sepsis: is individualized immuno-modulatory therapy the answer?
-
Boomer, J.S., Green, J.M., Hotchkiss, R.S., The changing immune system in sepsis: is individualized immuno-modulatory therapy the answer?. Virulence 5 (2014), 45–56.
-
(2014)
Virulence
, vol.5
, pp. 45-56
-
-
Boomer, J.S.1
Green, J.M.2
Hotchkiss, R.S.3
-
15
-
-
84903470168
-
T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-gamma production of natural killer cells via beta-arrestin 2-mediated negative signaling
-
Li, M., Xia, P., Du, Y., Liu, S., Huang, G., Chen, J., Zhang, H., Hou, N., Cheng, X., Zhou, L., Li, P., Yang, X., Fan, Z., T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-gamma production of natural killer cells via beta-arrestin 2-mediated negative signaling. J. Biol. Chem. 289 (2014), 17647–17657.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 17647-17657
-
-
Li, M.1
Xia, P.2
Du, Y.3
Liu, S.4
Huang, G.5
Chen, J.6
Zhang, H.7
Hou, N.8
Cheng, X.9
Zhou, L.10
Li, P.11
Yang, X.12
Fan, Z.13
-
16
-
-
84926151468
-
Nectins and nectin-like molecules in development and disease
-
Mandai, K., Rikitake, Y., Mori, M., Takai, Y., Nectins and nectin-like molecules in development and disease. Curr. Top. Dev. Biol. 112 (2015), 197–231.
-
(2015)
Curr. Top. Dev. Biol.
, vol.112
, pp. 197-231
-
-
Mandai, K.1
Rikitake, Y.2
Mori, M.3
Takai, Y.4
-
17
-
-
57849101994
-
The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
-
Yu, X., Harden, K., Gonzalez, L.C., Francesco, M., Chiang, E., Irving, B., Tom, I., Ivelja, S., Refino, C.J., Clark, H., Eaton, D., Grogan, J.L., The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells. Nat. Immunol. 10 (2009), 48–57.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 48-57
-
-
Yu, X.1
Harden, K.2
Gonzalez, L.C.3
Francesco, M.4
Chiang, E.5
Irving, B.6
Tom, I.7
Ivelja, S.8
Refino, C.J.9
Clark, H.10
Eaton, D.11
Grogan, J.L.12
-
18
-
-
84960158903
-
Melanoma cells control antimelanoma CTL responses via interaction between TIGIT and CD155 in the effector phase
-
Inozume, T., Yaguchi, T., Furuta, J., Harada, K., Kawakami, Y., Shimada, S., Melanoma cells control antimelanoma CTL responses via interaction between TIGIT and CD155 in the effector phase. J. Invest. Dermatol. 136 (2016), 255–263.
-
(2016)
J. Invest. Dermatol.
, vol.136
, pp. 255-263
-
-
Inozume, T.1
Yaguchi, T.2
Furuta, J.3
Harada, K.4
Kawakami, Y.5
Shimada, S.6
-
19
-
-
61449154547
-
Immunodesign of experimental sepsis by cecal ligation and puncture
-
Rittirsch, D., Huber-Lang, M.S., Flierl, M.A., Ward, P.A., Immunodesign of experimental sepsis by cecal ligation and puncture. Nat. Protoc. 4 (2009), 31–36.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 31-36
-
-
Rittirsch, D.1
Huber-Lang, M.S.2
Flierl, M.A.3
Ward, P.A.4
-
20
-
-
77949759544
-
Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock
-
Zhong, J., Yang, P., Muta, K., Dong, R., Marrero, M., Gong, F., Wang, C.Y., Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock. PLoS One, 5, 2010, e9593.
-
(2010)
PLoS One
, vol.5
, pp. e9593
-
-
Zhong, J.1
Yang, P.2
Muta, K.3
Dong, R.4
Marrero, M.5
Gong, F.6
Wang, C.Y.7
-
21
-
-
84922768204
-
Intrinsic and extrinsic mechanisms of dendritic morphogenesis
-
Dong, X., Shen, K., Bulow, H.E., Intrinsic and extrinsic mechanisms of dendritic morphogenesis. Annu. Rev. Physiol. 77 (2015), 271–300.
-
(2015)
Annu. Rev. Physiol.
, vol.77
, pp. 271-300
-
-
Dong, X.1
Shen, K.2
Bulow, H.E.3
-
22
-
-
0038106475
-
Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells
-
Tinsley, K.W., Grayson, M.H., Swanson, P.E., Drewry, A.M., Chang, K.C., Karl, I.E., Hotchkiss, R.S., Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells. J. Immunol. 171 (2003), 909–914.
-
(2003)
J. Immunol.
, vol.171
, pp. 909-914
-
-
Tinsley, K.W.1
Grayson, M.H.2
Swanson, P.E.3
Drewry, A.M.4
Chang, K.C.5
Karl, I.E.6
Hotchkiss, R.S.7
-
23
-
-
67650500800
-
CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation
-
Zanoni, I., Ostuni, R., Capuano, G., Collini, M., Caccia, M., Ronchi, A.E., Rocchetti, M., Mingozzi, F., Foti, M., Chirico, G., Costa, B., Zaza, A., Ricciardi-Castagnoli, P., Granucci, F., CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation. Nature 460 (2009), 264–268.
-
(2009)
Nature
, vol.460
, pp. 264-268
-
-
Zanoni, I.1
Ostuni, R.2
Capuano, G.3
Collini, M.4
Caccia, M.5
Ronchi, A.E.6
Rocchetti, M.7
Mingozzi, F.8
Foti, M.9
Chirico, G.10
Costa, B.11
Zaza, A.12
Ricciardi-Castagnoli, P.13
Granucci, F.14
-
24
-
-
80655149467
-
Intranodal interaction with dendritic cells dynamically regulates surface expression of the co-stimulatory receptor CD226 protein on murine T cells
-
Seth, S., Qiu, Q., Danisch, S., Maier, M.K., Braun, A., Ravens, I., Czeloth, N., Hyde, R., Dittrich-Breiholz, O., Forster, R., Bernhardt, G., Intranodal interaction with dendritic cells dynamically regulates surface expression of the co-stimulatory receptor CD226 protein on murine T cells. J. Biol. Chem. 286 (2011), 39153–39163.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 39153-39163
-
-
Seth, S.1
Qiu, Q.2
Danisch, S.3
Maier, M.K.4
Braun, A.5
Ravens, I.6
Czeloth, N.7
Hyde, R.8
Dittrich-Breiholz, O.9
Forster, R.10
Bernhardt, G.11
-
25
-
-
33746190736
-
Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality
-
Osuchowski, M.F., Welch, K., Siddiqui, J., Remick, D.G., Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J. Immunol. 177 (2006), 1967–1974.
-
(2006)
J. Immunol.
, vol.177
, pp. 1967-1974
-
-
Osuchowski, M.F.1
Welch, K.2
Siddiqui, J.3
Remick, D.G.4
-
26
-
-
60849114014
-
Compensatory anti-inflammatory response syndrome
-
Adib-Conquy, M., Cavaillon, J.M., Compensatory anti-inflammatory response syndrome. Thromb. Haemost. 101 (2009), 36–47.
-
(2009)
Thromb. Haemost.
, vol.101
, pp. 36-47
-
-
Adib-Conquy, M.1
Cavaillon, J.M.2
-
27
-
-
34250359119
-
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis
-
Delano, M.J., Scumpia, P.O., Weinstein, J.S., Coco, D., Nagaraj, S., Kelly-Scumpia, K.M., O'Malley, K.A., Wynn, J.L., Antonenko, S., Al-Quran, S.Z., Swan, R., Chung, C.S., Atkinson, M.A., Ramphal, R., Gabrilovich, D.I., Reeves, W.H., Ayala, A., Phillips, J., Laface, D., Heyworth, P.G., Clare-Salzler, M., Moldawer, L.L., MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J. Exp. Med. 204 (2007), 1463–1474.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1463-1474
-
-
Delano, M.J.1
Scumpia, P.O.2
Weinstein, J.S.3
Coco, D.4
Nagaraj, S.5
Kelly-Scumpia, K.M.6
O'Malley, K.A.7
Wynn, J.L.8
Antonenko, S.9
Al-Quran, S.Z.10
Swan, R.11
Chung, C.S.12
Atkinson, M.A.13
Ramphal, R.14
Gabrilovich, D.I.15
Reeves, W.H.16
Ayala, A.17
Phillips, J.18
Laface, D.19
Heyworth, P.G.20
Clare-Salzler, M.21
Moldawer, L.L.22
more..
-
28
-
-
43349107987
-
Regulatory T cell populations in sepsis and trauma
-
Venet, F., Chung, C.S., Monneret, G., Huang, X., Horner, B., Garber, M., Ayala, A., Regulatory T cell populations in sepsis and trauma. J. Leukoc. Biol. 83 (2008), 523–535.
-
(2008)
J. Leukoc. Biol.
, vol.83
, pp. 523-535
-
-
Venet, F.1
Chung, C.S.2
Monneret, G.3
Huang, X.4
Horner, B.5
Garber, M.6
Ayala, A.7
-
29
-
-
0035838984
-
Dendritic cells: specialized and regulated antigen processing machines
-
Mellman, I., Steinman, R.M., Dendritic cells: specialized and regulated antigen processing machines. Cell 106 (2001), 255–258.
-
(2001)
Cell
, vol.106
, pp. 255-258
-
-
Mellman, I.1
Steinman, R.M.2
-
30
-
-
16244379546
-
Regulatory T cells and intestinal homeostasis
-
Coombes, J.L., Robinson, N.J., Maloy, K.J., Uhlig, H.H., Powrie, F., Regulatory T cells and intestinal homeostasis. Immunol. Rev. 204 (2005), 184–194.
-
(2005)
Immunol. Rev.
, vol.204
, pp. 184-194
-
-
Coombes, J.L.1
Robinson, N.J.2
Maloy, K.J.3
Uhlig, H.H.4
Powrie, F.5
|